This protocol outlines methods and tips to improve mouse xenograft studies using Cultrex® Basement Membrane Extract (BME). Some specific tips and considerations you can find in this protocol include:
- Tumor tissue processing and injection tips to improve initiation of tumor cells in mouse xenografts
- Considerations for xenograft injection site, optimizing cell number, and identifying mouse strains
- Use of Cultrex BME to enhance the tumor cell take and growth in xenograft studies in mice