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Potent and selective NMDA receptor antagonist; more active form of DL-AP5
Potent and selective NMDA antagonist
Non-competitive NMDA antagonist; acts at ion channel site
Potent and selective NMDA antagonist; sodium salt of DL-AP5
Potent and selective non-NMDA iGluR antagonist
GluN2B-selective NMDA antagonist
Potent kynurenine 3-monooxygenase (KMO) inhibitor
NMDA antagonist; acts at ion channel site
Potent competitive inhibitor of L-glutamate uptake
Potent NMDA antagonist; more active enantiomer of (RS)-CPP
Potent NMDA antagonist; acts at glycine site
Non-competitive NMDA antagonist; also σ ligand
Highly potent NMDA antagonist
Potent and selective NMDA antagonist; acts at glycine site
NMDA antagonist; less active enantiomer of (+)-MK 801
Potent and selective NMDA antagonist; less active form of DL-AP5
NMDA antagonist; acts at glycine site
Peripherally acting μ agonist; Ca2+ channel blocker
NMDA antagonist; acts at glycine site
Potent competitive NMDA antagonist
Competitive NMDA antagonist
Potent competitive NMDA antagonist
Potent, selective and competitive NMDA antagonist
Potent and selective NMDA antagonist
Potent non-competitive NMDA antagonist; antinociceptive
Potent and selective NMDA antagonist; acts at the glycine site
GluN2B-selective NMDA antagonist
GluN2C/GluN2D-selective NMDA antagonist
Non-competitive NMDA antagonist
KV7 channel activator; also GABAA modulator and indirect NMDA antagonist
Non-competitive NMDA receptor antagonist
Potent competitive inhibitor of L-glutamate uptake. Sodium salt of 7-Chlorokynurenic acid (Cat. No. 0237)
Potent NMDA antagonist, acts at glycine site; sodium salt of 5,7-Dichlorokynurenic acid
GluN1/GluN2A-selective NMDA antagonist
NMDA receptor antagonist; enantiomer of ketamine hydrochloride (Cat. No. 3131); neuroprotective
GluN2C/GluN2D-selective NMDA antagonist
Potent and noncompetitive NMDA antagonist
Non-competitive and GluN2C/GluN2D-selective NMDA antagonist
Potent and GluN2A-selective NMDA antagonist
NMDA antagonist; antidepressant; may not display psychotomimetic or addictive side effects of (S)-ketamine