5,7-Dichlorokynurenic acid sodium salt

Catalog # Availability Size / Price Qty
3698/10
3698/50
5,7-Dichlorokynurenic acid sodium salt | CAS No. 1184986-70-6 | NMDA Receptor Antagonists
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Description: Potent NMDA antagonist, acts at glycine site; sodium salt of 5,7-Dichlorokynurenic acid

Chemical Name: 5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid sodium salt

Purity: ≥98%

Product Details
Citations (2)
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Biological Activity

5,7-Dichlorokynurenic acid sodium salt is a sodium salt of 5,7-Dichlorokynurenic acid (Cat. No. 0286), a potent antagonist at the glycine site of the NMDA receptor (Ki = 79 nM vs. [3H]-glycine).

Technical Data

M.Wt:
280.04
Formula:
C10H4Cl2NNaO3
Solubility:
Soluble to 100 mM in 1eq. NaOH
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
1184986-70-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Activity of 5,7-dichlorokynurenic acid. A potent antagonist at the NMDA receptor-associated glycine binding site.
    Baron et al.
    Mol.Pharmacol., 1990;38:554
  2. Substituted kynurenic acid derivatives. Potent and selective antagonists at the glycine site on the NMDA receptor.
    Moore et al.
    Eur.Fed.Med.Chem. (under auspices of IUPAC) XIth I, 1990;

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Citations for 5,7-Dichlorokynurenic acid sodium salt

The citations listed below are publications that use Tocris products. Selected citations for 5,7-Dichlorokynurenic acid sodium salt include:

2 Citations: Showing 1 - 2

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