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DNA cross-linking antitumor agent
JNK, SAPK and p38 activator
Protein synthesis inhibitor
mRNA splicing inhibitor; antitumor
Inhibitor of protein synthesis
Thymidylate synthetase inhibitor
DNA cross-linking antitumor agent
Inhibitor of DNA and RNA polymerase
DNA cross-linking antitumor agent
Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive
Purine analog; inhibits DNA synthesis
Nucleoside analog; inhibits DNA replication
DNA topoisomerase II inhibitor
Inhibitor of protein synthesis; antileukemic agent
Selective telomerase inhibitor
Antibiotic; inhibits bacterial DNA synthesis
Antibiotic; inhibits protein, DNA and RNA synthesis in gram-positive bacteria
Inhibits eIF4E:eIF4G subunit interaction
DNA polymerase α, δ and ε inhibitor
Pre-mRNA splicing inhibitor; cell permeable
Cx36 and Cx50 gap channel blocker; also antimalarial and antischistosomal
Antibiotic; inhibits protein synthesis in gram-positive bacteria
Topoisomerase II inhibitor
Antibiotic; inhibits bacterial DNA synthesis
Inhibitor of RNA polymerase II
Inhibitor of RNA helicase A (RHA)
Aminoglycoside antibiotic; used in cell culture
Cytotoxic nucleoside analog; inhibits RNA synthesis
Blocks eIF4E activity; antiviral guanosine analog
Werner syndrome helicase (WRN) inhibitor
RNA polymerase I inhibitor; also p53 pathway activator
Allosteric inhibitor of RAD52; also APE1 inhibitor
High affinity competitive prolyl-tRNA synthetase inhibitor
RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor
Purine nuceloside analog; inhibits DNA synthesis
RAD51 recombinase inhibitor
Inhibits formation of miR-210
Thymidine analog for labeling DNA; can be linked to a fluorophore by click chemistry
Inhibits coronavirus RNA replication; impairs double membrane vesicle (DMV) formation
Prodrug of antiviral nucleoside analog; inhibits SARS-CoV, SARS-CoV-2 and MERS-CoV infection