Products for Angiogenesis Research

1. Saharinen, P. et al. (2008) Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts. Nat. Cell Biol. 10:527.

   Recombinant Human Angiopoietin-1 (Catalog # 923-AN)

   Recombinant Human Angiopoietin-2 (Catalog # 623-AN)

   Sample: Mouse b-END3 brain-derived microvascular endothelial cells, human umbilical vein, and human EA.hy926 endothelial cells
   Application: Bioassay- signaling

   Recombinant Human Tie-2/Fc Chimera (Catalog # 313-TI)

   Sample: Human umbilical vein endothelial cells
   Application: Pull-down and Cell adhesion assays

   Recombinant Human VEGF R3/Flt-4/Fc Chimera (Catalog # 349-F4)

   Recombinant Human Tie-1/Fc Chimera (Catalog # 619-TI)

   Sample: Human umbilical vein endothelial cells
   Application: Pull-down and Bead aggregation assays

   Phospho-Tie-2 (Y992) Polyclonal Antibody (Catalog # AF2720)

   Human Tie-2 Polyclonal Antibody (Catalog # AF313)

   Sample: Human umbilical vein, human pulmonary microvascular, and human EA.hy926 endothelial cells
   Applications: Western Blot, Immunohistochemistry
2. Shim, W. et al. (2008) Structural stability of neoangiogenic intramyocardial microvessels supports functional recovery in chronic ischemic myocardium.
   J. Mol. Cell. Cardiol. 45:70.

   Human Angiopoietin-1 Quantikine® ELISA Kit (Catalog # DANG10)

   Human Angiopoietin-2 Quantikine ELISA Kit (Catalog # DANG20)

   Human VEGF Quantikine ELISA Kit (Catalog # DVE00)

   Sample: Porcine myocardium homogenate
   Application: ELISA
3. Bae, Y. et al. (2009) Upregulation of fibroblast growth factor-2 by visfatin that promotes endothelial angiogenesis. Biochem. Biophys. Res. Commun. 379:206.

   Human FGF basic Quantikine ELISA Kit (Catalog # DFB50)

   Sample: Human microvascular endothelial cell supernates
   Application: ELISA

   Human FGF basic Polyclonal Antibody (Catalog # AF-233-NA)

   Sample: Rat aortic ring explant
   Application: Neutralization
4. Crawford, Y. et al. (2009) PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. Cancer Cell 15:21.

   Recombinant Human PDGF-DD (Catalog # 1159-SB)

   Recombinant Mouse VEGF 164 (Catalog # 493-MV)

   Recombinant Human PDGF-CC (Catalog # 1687-CC)

   Application: Western blot specificity control

   Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha (Catalog # 350-NS)

   Sample: Mouse normal skin and tumor-associated fibroblasts
   Applications: In vivo Matrigel® plug assay, Western blot specificity control

   Recombinant Mouse PDGF-CC (Catalog # 1447-PC)

   Sample: Mouse normal skin and tumor-associated fibroblasts and endothelial cells
   Applications: In vivo Matrigel plug assay, Bioassay- migration, Western blot positive control

   Mouse PDGF-C Polyclonal Antibody (Catalog # AF1447)

   Sample: Mouse normal skin and tumor-associated fibroblasts; Recombinant mouse PDGF-CC
   Applications: Neutralization of In vivo Matrigel plug assay, Western blot

   Mouse VEGF Quantikine ELISA Kit (Catalog # MMV00)

   Sample: Mouse normal skin and tumor-associated fibroblast tumor supernates
   Application: ELISA
5. Zacchigna, S. et al. (2008) Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice. J. Clin. Invest. 118:2062.

   Rat Neuropilin-1 Polyclonal Antibody (Catalog # AF566)

   Rat Neuropilin-2 Polyclonal Antibody (Catalog # AF567)

   Sample: Mouse muscle
   Application: Immunohistochemistry

   Recombinant Human VEGF 165 (Catalog # 293-VE)

   Recombinant Human VEGF (aa 207-318) (Catalog # 298-VS)

   Recombinant Human Semaphorin 3A/Fc Chimera (Catalog # 1250-S3)

   Sample: Human smooth muscle and endothelial cells
   Application: Bioassay- migration
6. Tammela, T. et al. (2008) Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature 454:656.

   Mouse VEGF R3/Flt-4 Polyclonal Antibody (Catalog # AF743)

   Mouse VEGF R2/Flk-1 Polyclonal Antibody (Catalog # AF644)

   Mouse DLL4 Polyclonal Antibody (Catalog # AF1389)

   Sample: Mouse retina and skin
   Application: Immunohistochemistry
7. Zhang, Z. et al. (2008) a2b1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner. Blood 111:1980.

   Recombinant Mouse VEGF 164 (Catalog # 493-MV)

   Recombinant Human PlGF (Catalog # 264-PG)

   Sample: Mouse and mouse thoracic aortal explant
   Application: In vivo Matrigel plug assay, Bioassay- aortic ring assay

   Recombinant Human VEGF-C (Catalog # 2179-VC)

   Sample: Mouse
   Application: In vivo Matrigel plug assay

   Mouse VEGF R2/Flk-1 Monoclonal Antibody (Catalog # MAB4431)

   Mouse VEGF R1/Flt-1 Polyclonal Antibody (Catalog # AF471)

   Sample: Tumor, pulmonary endothelial cells, and lysates
   Application: Immunohistochemistry, Neutralization, Western blot

   Mouse PlGF-2 Quantikine ELISA Kit (Catalog # MP200)

   Mouse VEGF Quantikine ELISA Kit (Catalog # MMV00)

   Sample: Mouse Lewis lung carcinoma and B16-F10 melanoma cell line supernates
   Application: ELISA
8. Devy, L et al. (2009) Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis. Cancer Res. 69:1517.

   Recombinant Human MMP-14 (Catalog # 918-MP)

   Sample: Human Fab displaying phage library
   Application: Library screening and selection

   Human VEGF Monoclonal Antibody (Catalog # MAB293)

   Sample: Human umbilical vein endothelial cells
   Application: Neutralization

   Human MMP-14 Monoclonal Antibody (Catalog # MAB9181)

   Sample: Human umbilical vein endothelial, HT-1080 fibrosarcoma, MDA-MB-231, and MCF-7 breast cancer cell lysates
   Application: Western Blot

Matrigel is a registereds trademark of Becton, Dickinson and Company.
Quantikine is a registered trademark of R&D Systems, Inc.