Does the Human VEGF Quantikine® ELISA kit (Catalog # DVE00) detect mouse VEGF?

No, the kit does not detect mouse VEGF. Specificity testing with recombinant mouse VEGF 120 and VEGF 164 showed no cross-reactivity. For the detection of mouse VEGF, please refer to the Mouse VEGF Quantikine® ELISA kit (Catalog # MMV00).

Does the Human VEGF Quantikine® ELISA kit (Catalog # DVE00) detect porcine samples?

Our lab has not tested porcine samples in the kit, however many customers have published use of the kit with porcine samples. Links to these references can be found in the citations tab by selecting for Porcine in the Species filter.

Is the heterodimer VEGF165/PlGF detected by DVE00?

VEGF165/PlGF is not detected by this kit. Recombinant human VEGF165/PlGF was prepared at 50 ng/mL and assayed for cross-reactivity, with negative results.

Is there a protocol for using cell lysates with the Human VEGF Quantikine® ELISA Kit (Catalog # DVE00)?

R&D Systems does not have a validated cell lysate protocol available for this kit. However, many customers have published use of the kit with cell lysates. Links to these references can be found in the citations tab. Generally, the use of detergents in the lysis buffer should be avoided when preparing cell samples. A better option is to lyse the cells via freeze/thaw cycles or by sonication.

Does the Human VEGF Quantikine® ELISA kit (Catalog # DVE00) detect human VEGF121?

Yes, the kit detects VEGF121. In specificity testing, 100% cross-reactivity was observed with recombinant human VEGF121.

How long can samples (cell cultures, serum, and plasma) be stored and still be stable for measuring VEGF using the DVE00 Human VEGF Quantikine® ELISA Kit?

R&D Systems does not evaluate sample stability. Variations in sample collection, processing, and storage may affect stability of samples. It is recommend to assay sample immediately after collection when possible, or aliquot into single use volumes and store samples frozen. Avoid repeat freeze-thaw cycles with the stored samples to avoid protein degradation.

Human VEGF ELISA Kit Kit - Quantikine

Name: Human VEGF Quantikine ELISA Kit
Brand: R&D Systems
SKU: DVE00
Rating: 4.9 (29 reviews)

Catalog #: DVE00
685 Citations 29 Reviews Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
SVE00
PDVE00
DVE00

Control Products Available

QC01-1: Quantikine Immunoassay Control Group 1

Best Seller

Human VEGF ELISA Cell Culture Supernate Standard Curve

3 Images

All VEGF ELISAs

Product Details

Procedure

Citations (685)

FAQs

Supplemental Products

Reviews (29)

Summary Sample Values Precision Recovery Linearity Data Examples Product Datasheets Preparation and Storage Background Related Research Areas

Human VEGF Quantikine ELISA Kit Summary

Assay Type

Solid Phase Sandwich ELISA

Format

96-well strip plate

Assay Length

4.5 hours

Sample Type & Volume Required Per Well

Cell Culture Supernates (200 uL), Serum (100 uL), EDTA Plasma (100 uL), Heparin Plasma (100 uL), Citrate Plasma (100 uL)

Sensitivity

9 pg/mL

Assay Range

15.6 - 1,000 pg/mL (Cell Culture Supernates), 31.3 - 2,000 pg/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma)

Specificity

Natural and recombinant human VEGF. This assay also recognizes recombinant human VEGF_165b.

Cross-reactivity

Cross-reactivity observed with 1 or more available related molecules.Cross-species reactivity observed with 1 or more species tested.

Interference

Interference observed with 1 or more available related molecules.

Sample Values

Serum/Plasma - Samples from apparently healthy volunteers were evaluated for the presence of human VEGF in this assay. No medical histories were available for the donors used in this study.

Sample Type	Mean of detectable (pg/mL)	% Detectable	Range (pg/mL)
Serum (n=37)	220	100	62-707
EDTA plasma (n=37)	61	24	ND-115
Heparin plasma (n=37)	41	22	ND-55
Citrate plasma (n=37)	___	0	ND

ND=Non-Detectable

Cell Culture Supernates:

Human peripheral blood mononuclear cells (10 x 106 cells/mL) were cultured in RPMI supplemented with 5% fetal bovine serum, 50 μM beta -mercaptoethanol, 2 mM L-glutamine, 100 U/mL penicillin, and 100 μg/mL streptomycin sulfate. The cells were cultured unstimulated or stimulated with 10 μg/mL PHA for 5 days. Aliquots of the cell culture supernates were removed, assayed for levels of human VEGF, and measured 87.1 pg/mL and 1041 pg/mL, respectively.

PC-3 human prostate cancer cells were cultured in RPMI supplemented with 10% fetal bovine serum, 2 mM L-glutamine, 100 U/mL penicillin, and 100 μg/mL streptomycin sulfate. The cells were cultured unstimulated or stimulated with 60 nM of PMA for 24 hours. Aliquots of the cell culture supernates were removed, assayed for levels of human VEGF, and measured 3373 pg/mL and 3652 pg/mL, respectively.

JEG-3 human epithelial choriocarcinoma cells were cultured in MEM + NEAA supplemented with 10% fetal bovine serum, 2 mM L-glutamine, 100 U/mL penicillin, and 100 μg/mL streptomycin sulfate. The cells were cultured unstimulated or stimulated with 100 ng/mL of LPS for 1 day. Aliquots of the cell culture supernates were removed, assayed for levels of human VEGF, and measured 1538 pg/mL and 1938 pg/mL, respectively.

Product Summary

The Quantikine Human VEGF Immunoassay is a 4.5 hour solid phase ELISA designed to measure VEGF₁₆₅ levels in cell culture supernates, serum, and plasma. It contains Sf 21-expressed recombinant human VEGF₁₆₅ and antibodies raised against the recombinant protein. Results obtained for naturally occurring human VEGF and recombinant human VEGF₁₂₁ showed linear curves that were parallel to the standard curves obtained using the Quantikine Human VEGF Immunoassay standards. These results indicate that this kit can be used to determine relative mass values for natural human VEGF.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision

Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in forty separate assays to assess inter-assay precision. Assays were performed by at least three technicians using two lots of components

Cell Culture Supernates

	Intra-Assay Precision			Inter-Assay Precision
Sample	1	2	3	1	2	3
n	20	20	20	40	40	40
Mean (pg/mL)	29.1	123	531	32.8	128	495
Standard Deviation	1.9	5	18.4	2.8	6.4	33
CV%	6.5	4.1	3.5	8.5	5	6.7

Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma

	Intra-Assay Precision			Inter-Assay Precision
Sample	1	2	3	1	2	3
n	20	20	20	40	40	40
Mean (pg/mL)	53.7	235	910	64.5	250	1003
Standard Deviation	3.6	10.6	46.2	5.7	17.4	61.7
CV%	6.7	4.5	5.1	8.8	7	6.2

Recovery

The recovery of human VEGF spiked to three different levels throughout the range of the assay in various matrices was evaluated.

Sample Type	Average % Recovery	Range %
Cell Culture Media (n=5)	102	95-111
Citrate Plasma (n=5)	100	88-113
EDTA Plasma (n=5)	97	82-113
Heparin Plasma (n=5)	93	82-102
Serum (n=5)	102	92-115

Linearity

To assess linearity of the assay, samples were spiked with high concentrations of human VEGF and diluted with the appropriate calibrator diluent to produce samples with values within the dynamic range of the assay.

Scientific Data

N/A

View Larger

Human VEGF ELISA Cell Culture Supernate Standard Curve

N/A

View Larger

Human VEGF ELISA Serum/Plasma Standard Curve

Product Datasheets

Product Datasheet

COA

SDS

Preparation and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: VEGF

Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult (1-3). It is a member of the PDGF family that is characterized by the presence of eight conserved cysteine residues in a cystine knot structure and the formation of antiparallel disulfide-linked dimers (4). Humans express alternately spliced isoforms of 121, 145, 165, 183, 189, and 206 amino acids (aa) in length (4). VEGF₁₆₅ appears to be the most abundant and potent isoform, followed by VEGF₁₂₁ and VEGF₁₈₉ (3, 4). Isoforms other than VEGF₁₂₁ contain basic heparin-binding regions and are not freely diffusible (4). Human VEGF₁₆₅ shares 88% aa sequence identity with corresponding regions of mouse and rat VEGF. VEGF is expressed in multiple cells and tissues including skeletal and cardiac muscle (5, 6), hepatocytes (7), osteoblasts (8), neutrophils (9), macrophages (10), keratinocytes (11), brown adipose tissue (12), CD34⁺ stem cells (13), endothelial cells (14), fibroblasts, and vascular smooth muscle cells (15). VEGF expression is induced by hypoxia and cytokines such as IL-1, IL-6, IL-8, oncostatin M, and TNF-alpha (3, 4, 9, 16). VEGF isoforms are differentially expressed during development and in the adult (3).

VEGF dimers bind to two related receptor tyrosine kinases, VEGF R1 (also called Flt-1) and VEGF R2 (Flk-1/KDR), and induce their homodimerization and autophosphorylation (3, 4, 7, 17, 18). These receptors have seven extracellular immunoglobulin-like domains and an intracellular split tyrosine kinase domain. They are expressed on vascular endothelial cells and a range of non-endothelial cells. Although VEGF affinity is highest for binding to VEGF R1, VEGF R2 appears to be the primary mediator of VEGF angiogenic activity (3, 4). VEGF165 also binds the semaphorin receptor, neuropilin-1, which promotes complex formation with VEGF R2 (19).

VEGF is best known for its role in vasculogenesis. During embryogenesis, VEGF regulates the proliferation, migration, and survival of endothelial cells (3, 4), thus regulating blood vessel density and size, but playing no role in determining vascular patterns. VEGF promotes bone formation through osteoblast and chondroblast recruitment and is also a monocyte chemoattractant (20-22). After birth, VEGF maintains endothelial cell integrity and is a potent mitogen for micro- and macro-vascular endothelial cells. In adults, VEGF functions mainly in wound healing and the female reproductive cycle (3). In diseased tissues, VEGF promotes vascular permeability. It is thus thought to contribute to tumor metastasis by promoting both extravasation and tumor angiogenesis (23, 24). Various strategies have been employed therapeutically to antagonize VEGF-mediated tumor angiogenesis (25). Circulating VEGF levels correlate with disease activity in autoimmune diseases such as rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (26).

Long Name:

Vascular Endothelial Growth Factor

Entrez Gene IDs:

7422 (Human); 22339 (Mouse); 83785 (Rat); 281572 (Bovine); 403802 (Canine); 493845 (Feline); 30682 (Zebrafish)

Alternate Names:

MVCD1; VAS; vascular endothelial growth factor A; Vascular permeability factor; Vasculotropin; VEGF; VEGFA; VEGF-A; VEGFMGC70609; VPF; VPFvascular endothelial growth factor

Related Research Areas

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Assay Procedure

Refer to the product datasheet for the complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.

Prepare all reagents, standard dilutions, and samples as directed in the product insert.

Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

For Serum & Plasma Samples: Add 100 µL of Assay Diluent to each well.
For Cell Culture Supernate Samples: Add 50 µL Assay Diluent to each well.

Add Assay Diluent

For Serum & Plasma Samples: Add 100 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
For Cell Culture Supernate Samples: Add 200 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.

Aspirate each well and wash, repeating the process twice for a total of 3 washes.

Add Standard, Control, or Sample

Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.

Aspirate and wash 3 times.

200 µL Conjugate

Add 200 µL Substrate Solution to each well.

For Serum & Plasma Samples: Incubate at room temperature for 25 minutes. PROTECT FROM LIGHT. For Cell Culture Supernate Samples: Incubate at room temperature for 20 minutes.
PROTECT FROM LIGHT.

200 µL Substrate Solution

50 µL Stop Solution

Citations for Human VEGF Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

685 Citations: Showing 1 - 10
Filter your results:

Filter by:

Human bone tissue-derived ECM hydrogels: Controlling physicochemical, biochemical, and biological properties through processing parameters
Authors: Kim, YH;Cidonio, G;Kanczler, JM;Oreffo, RO;Dawson, JI;
Bioactive materials
Species: Human
Sample Types: Bone Extracts
Heme: A link between hemorrhage and retinopathy of prematurity progression
Authors: Gáll, T;Peth?, D;Erdélyi, K;Egri, V;Balla, JG;Nagy, A;Nagy, A;Póliska, S;Gram, M;Gábriel, R;Nagy, P;Balla, J;Balla, G;
Redox biology
Species: Human
Sample Types: Cell Culture Supernates
Anti-Inflammatory and Anti-(Lymph)angiogenic Properties of an ABCB5+ Limbal Mesenchymal Stem Cell Population
Authors: Meshko, B;Volatier, TLA;Mann, J;Kluth, MA;Ganss, C;Frank, MH;Frank, NY;Ksander, BR;Cursiefen, C;Notara, M;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
Effects of dexmedetomidine and ketorolac applied for patient?controlled analgesia on the balance of Th1/Th2 and level of VEGF in patients undergoing laparoscopic surgery for cervical cancer: A randomized controlled trial
Authors: Ao, L;Shi, J;Gan, J;Yu, W;Du, H;
Oncology letters
Species: Human
Sample Types: Serum
Tumor necrosis factor-?-treated human adipose-derived stem cells enhance inherent radiation tolerance and alleviate in vivo radiation-induced capsular contracture
Authors: Sutthiwanjampa, C;Kang, SH;Kim, MK;Hwa Choi, J;Kim, HK;Woo, SH;Bae, TH;Kim, WJ;Kang, SH;Park, H;
Journal of advanced research
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA
Bioactive baicalin rhamno-nanocapsules as phytotherapeutic platform for treatment of acute myeloid leukemia
Authors: Heikal, LA;El-Habashy, SE;El-Kamel, AH;Mehanna, RA;Ashour, AA;
International journal of pharmaceutics
Species: Human
Sample Types: Cell Culture Supernates
Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells
Authors: Donnelly, H;Ross, E;Xiao, Y;Hermantara, R;Taqi, AF;Doherty-Boyd, WS;Cassels, J;Tsimbouri, PM;Dunn, KM;Hay, J;Cheng, A;Meek, RMD;Jain, N;West, C;Wheadon, H;Michie, AM;Peault, B;West, AG;Salmeron-Sanchez, M;Dalby, MJ;
Nature communications
Species: Human
Sample Types: Cell Culture Supernates
Development of composite functional tissue sheets using hiPSC-CMs and hADSCs to improve the cardiac function after myocardial infarction
Authors: Zhang, J;Li, J;Qu, X;Liu, Y;Sun, L;Harada, A;Hua, Y;Sougawa, N;Tabata, A;Liu, L;Miyagawa, S;
Bioactive materials
Species: Human
Sample Types: Cell Culture Supernates
Delineating three-dimensional behavior of uveal melanoma cells under anchorage independent or dependent conditions
Authors: Goyeneche, AA;Lasiste, JME;Abdouh, M;Bustamante, P;Burnier, JV;Burnier, MN;
Cancer cell international
Species: Human
Sample Types: Cell Culture Supernates
Doxazosin inhibits vasculogenic mimicry in human non?small cell lung cancer through inhibition of the VEGF?A/VE?cadherin/mTOR/MMP pathway
Authors: Hsu, JL;Leu, WJ;Hsu, LC;Hsieh, CH;Guh, JH;
Oncology letters
Species: Human
Sample Types: Cell Culture Supernates

Thrombospondin-1, BIM and CFH polymorphisms and response to anti-VEGF treatment in neovascular age- related macular degeneration patients
Authors: Sorenson, CM;Gurel, Z;Song, YS;Peterson, KD;Blodi, BA;Sheibani, N;
PloS one
Species: Human
Sample Types: Plasma

C1q/Tumor Necrosis Factor-Related Protein-9 Is a Novel Vasculoprotective Cytokine That Restores High Glucose-Suppressed Endothelial Progenitor Cell Functions by Activating the Endothelial Nitric Oxide Synthase
Authors: Hu, Q;Qu, W;Zhang, T;Feng, J;Dong, X;Nie, R;Chen, J;Wang, X;Peng, C;Ke, X;
Journal of the American Heart Association
Species: Human
Sample Types: Cell Culture Supernates

Human induced pluripotent stem cell-derived planar neural organoids assembled on synthetic hydrogels
Authors: Majumder, J;Torr, EE;Aisenbrey, EA;Lebakken, CS;Favreau, PF;Richards, WD;Yin, Y;Chang, Q;Murphy, WL;
Journal of tissue engineering
Species: Human
Sample Types: Cell Lysates

Unravelling heterogeneous effects of cancer?associated fibroblasts on poor prognosis markers in breast cancer EM?G3 cell line: In vitro?targeted treatment (anti?IL-6, anti?VEGF-A, anti?MFGE8) based on transcriptomic profiling
Authors: Urban, L;Novák, ;?oma, M;Dvo?ánková, B;Lacina, L;áchová, J;Hradilová, M;Svato?ová, P;Kolá?, M;Strnad, H;B?ezinová, J;Smetana, K;Gál, P;Szabo, P;
Oncology reports
Species: Human
Sample Types: Cell Culture Supernates

Genetic Variability in VEGFA Gene Influences the Effectiveness of Tennis Elbow Therapy with PRP: A Two-Year Prospective Cohort Study
Authors: Niemiec, P;Jarosz, A;Balcerzyk-Mati?, A;Iwanicka, J;Nowak, T;Iwanicki, T;Gierek, M;Kalita, M;Garczorz, W;Francuz, T;Górczy?ska-Kosiorz, S;Kania, W;Szyluk, K;
International journal of molecular sciences
Species: Human
Sample Types: Plasma

Moderate intensity walking exercises reduce the body mass index and vascular inflammatory factors in postmenopausal women with obesity: a randomized controlled trial
Authors: Son, WH;Park, HT;Jeon, BH;Ha, MS;
Scientific reports
Species: Human
Sample Types: Serum

Mesenchymal stem cell-derived secretomes-enriched alginate/ extracellular matrix hydrogel patch accelerates skin wound healing
Authors: Kwon, JW;Savitri, C;An, B;Yang, SW;Park, K;
Biomaterials research
Species: Human
Sample Types: Cell Culture Supernates

Kaposi's sarcoma-associated herpesvirus viral protein kinase augments cell survival
Authors: Wu, XJ;Zhang, Z;Wong, JP;Rivera-Soto, R;White, MC;Rai, AA;Damania, B;
Cell death & disease
Species: Human
Sample Types: Cell Culture Supernates

Development of potent isoflavone-based formyl peptide receptor 1 (FPR1) antagonists and their effects in gastric cancer cell models
Authors: Francavilla, F;Sarcina, F;Schepetkin, IA;Kirpotina, LN;Contino, M;Schirizzi, A;De Leonardis, G;Khlebnikov, AI;D'Alessandro, R;Quinn, MT;Lacivita, E;Leopoldo, M;
European journal of medicinal chemistry
Species: Human
Sample Types: Cell Culture Supernates

Growth Factors Released from Advanced Platelet-Rich Fibrin in the Presence of Calcium-Based Silicate Materials and Their Impact on the Viability and Migration of Stem Cells of Apical Papilla
Authors: Smoczer, C;Yuth, KR;Askar, MA;Young, LA;Paurazas, SB;
Dentistry journal
Species: Human
Sample Types: Cell Culture Supernates

Periodontal Tissue Regeneration by Transplantation of Autologous Adipose Tissue-Derived Multi-Lineage Progenitor Cells With Carbonate Apatite
Authors: Takedachi, M;Kawasaki, K;Sawada, K;Sakura, K;Murata, M;Shimomura, J;Kawakami, K;Morimoto, C;Miki, K;Takeshita, N;Iwayama, T;Okura, H;Matsuyama, A;Saito, M;Kitamura, M;Murakami, S;
Cell transplantation
Species: Human
Sample Types: Cell Culture Supernates

A Novel Dual-Function Redox Modulator Relieves Oxidative Stress and Anti-Angiogenic Response in Placental Villus Explant Exposed to Hypoxia-Relevance for Preeclampsia Therapy
Authors: Pintye, D;Sziva, RE;Mastyugin, M;Young, BC;Jacas, S;Török, M;Salahuddin, S;Jagtap, P;Southan, GJ;Zsengellér, ZK;
Biology
Species: Human
Sample Types: Cell Culture Supernates

The TGF-?/UCHL5/Smad2 Axis Contributes to the Pathogenesis of Placenta Accreta
Authors: Hashimoto, K;Miyagawa, Y;Watanabe, S;Takasaki, K;Nishizawa, M;Yatsuki, K;Takahashi, Y;Kamata, H;Kihira, C;Hiraike, H;Sasamori, Y;Kido, K;Ryo, E;Nagasaka, K;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates

Circulating Soluble EPCR Levels Are Reduced in Patients with Ischemic Peripheral Artery Disease and Associated with Markers of Endothelial and Vascular Function
Authors: Krug, J;Bochenek, ML;Gogiraju, R;Laubert-Reh, D;Lackner, KJ;Münzel, T;Wild, PS;Espinola-Klein, C;Schäfer, K;
Biomedicines
Species: Human
Sample Types: Plasma

Fibroblasts are the most suitable cell source for regenerative medicine due to their high intracellular fibroblast growth factor 2 content
Authors: Yanagihara, M;Matsuno, Y;Ueno, K;Kurazumi, H;Suzuki, R;Tanaka, T;Hamano, K;
Biochemistry and biophysics reports
Species: Human
Sample Types: Cell Culture Supernates

Girdin regulates both migration and angiogenesis in pancreatic cancer cell lines
Authors: Hayashi, Y;Matsuo, Y;Denda, Y;Nonoyama, K;Murase, H;Ueda, G;Aoyama, Y;Kato, T;Omi, K;Imafuji, H;Saito, K;Morimoto, M;Ogawa, R;Takahashi, H;Mitsui, A;Kimura, M;Takiguchi, S;
Oncology reports
Species: Human
Sample Types: Cell Culture Supernates

Unraveling the Angiogenic Puzzle: Pre-Treatment sVEGFR1 and sVEGFR2 Levels as Promising Prognostic Indicators in Early-Stage Breast Cancer Patients
Authors: Zarychta, E;Bielawski, K;Wrzeszcz, K;Rhone, P;Ruszkowska-Ciastek, B;
International journal of molecular sciences
Species: Human
Sample Types: Plasma

Human Cord Blood-Endothelial Progenitor Cells Alleviate Intimal Hyperplasia of Arterial Damage in a Rat Stroke Model
Authors: Sun, H;Morihara, R;Feng, T;Bian, Z;Yu, H;Hu, X;Hu, X;Bian, Y;Sasaki, R;Fukui, Y;Takemoto, M;Yunoki, T;Nakano, Y;Abe, K;Yamashita, T;
Cell transplantation
Species: Human
Sample Types: Cell Culture Supernates

SYVN1 Promotes STAT3 Protein Ubiquitination and Exerts Antiangiogenesis Effects in Retinopathy of Prematurity Development
Authors: Chen, S;Zhang, J;Sun, D;Wu, Y;Fang, J;Wan, X;Li, S;Zhang, S;Gu, Q;Shao, Q;Dong, J;Xu, X;Wei, F;Sun, Q;
Investigative ophthalmology & visual science
Species: Human
Sample Types: Cell Culture Supernates

The splicing factor YBX1 promotes the progression of osteosarcoma by upregulating VEGF165 and downregulating VEGF165b
Authors: Quan, B;Li, Z;Yang, H;Li, S;Yan, X;Wang, Y;
Heliyon
Species: Human
Sample Types: Cell Culture Supernates

Increased Interleukin-36 beta Expression Promotes Angiogenesis in Japanese Atopic Dermatitis
Authors: Komaki, R;Miyagaki, T;Tanaka, M;Nakajima, K;Okano, T;Takeuchi, S;Kadono, T;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates, Serum

Alterations in choroidal vascular structures due to serum levels of vascular endothelial growth factor in patients with POEMS syndrome
Authors: Yokouchi, H;Nagasato, D;Mitamura, Y;Egawa, M;Tabuchi, H;Misawa, S;Kuwabara, S;Baba, T;
Scientific reports
Species: Human
Sample Types: Serum

Hypoxia induced responses are reflected in the stromal proteome of breast cancer
Authors: Kjølle, S;Finne, K;Birkeland, E;Ardawatia, V;Winge, I;Aziz, S;Knutsvik, G;Wik, E;Paulo, JA;Vethe, H;Kleftogiannis, D;Akslen, LA;
Nature communications
Species: Human
Sample Types: Cell Culture Supernates

Nailfold Videocapillaroscopic Alterations as Markers of Microangiopathy in COVID-19 Patients
Authors: Gualtierotti, R;Fox, SE;Da Silva Lameira, F;Giachi, A;Valenti, L;Borghi, MO;Meroni, PL;Cugno, M;Peyvandi, F;On Behalf Of The Capcovid Study Group, ;
Journal of clinical medicine
Species: Human
Sample Types:

Exploring the Therapeutic Potential of Elastase Inhibition in Age-Related Macular Degeneration in Mouse and Human
Authors: Navneet, S;Brandon, C;Simpson, K;Rohrer, B;
Cells
Species: Human
Sample Types: Cell Culture Supernates

sFlt-1-enriched exosomes induced endothelial cell dysfunction and a preeclampsia-like phenotype in mice
Authors: X Huang, L Jia, Y Jia, X Xu, R Wang, M Wei, H Li, H Peng, Y Wei, Q He, K Wang
Cytokine, 2023-04-14;166(0):156190.
Species: Human, Mouse
Sample Types: Cell Culture Supernates, Serum

L-type calcium channel blocker increases VEGF concentrations in retinal cells and human serum
Authors: A Kumar, S Mutter, EB Parente, V Harjutsalo, R Lithovius, S Mathavan, M Lehto, TP Hiltunen, KK Kontula, PH Groop
PLoS ONE, 2023-04-13;18(4):e0284364.
Species: Human
Sample Types: Serum

VEGF-A165 is the predominant VEGF-A isoform in platelets, while VEGF-A121 is abundant in serum and plasma from healthy individuals
Authors: M Yamakuchi, M Okawa, K Takenouchi, A Bibek, S Yamada, K Inoue, K Higurashi, A Tabaru, K Tanoue, Y Oyama, S Higashi, C Fujisaki, H Kanda, H Terasaki, T Sakamoto, Y Soga, T Hashiguchi
PLoS ONE, 2023-04-07;18(4):e0284131.
Species: Human
Sample Types: Serum

Reduced FRG1 expression promotes angiogenesis via activation of the FGF2-mediated ERK/AKT pathway
Authors: B Mukherjee, P Brahma, T Mohapatra, S Chawla, M Dixit
FEBS Open Bio, 2023-03-31;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Mesenchymal Stem/Stromal Cells in Skeletal Muscle Are Pro-Angiogenic, and the Effect Is Potentiated by Erythropoietin
Authors: Y Iso, S Usui, H Suzuki
Pharmaceutics, 2023-03-24;15(4):.
Species: Human
Sample Types: Cell Culture Supernates

Interaction between PD-L1 and soluble VEGFR1 in glioblastoma-educated macrophages
Authors: X Liu, Z Li, J Sun, Z Zhang, W Li
BMC Cancer, 2023-03-20;23(1):259.
Species: Human
Sample Types: Serum

Rapid and effective preparation of clonal bone marrow-derived mesenchymal stem/stromal cell sheets to reduce renal fibrosis
Authors: S Kameishi, CM Dunn, M Oka, K Kim, YK Cho, SU Song, DW Grainger, T Okano
Scientific Reports, 2023-03-17;13(1):4421.
Species: Human
Sample Types: Cell Culture Supernates

Endothelial Progenitor Cells Promote Osteosarcoma Progression and Invasiveness via AKT/PI3K Signaling
Authors: O Doppelt-Fl, A Younis, T Tamari, O Ginesin, T Shentzer-K, D Nikomarov, G Bar-Sela, BR Coyac, YG Assaraf, H Zigdon-Gil
Cancers, 2023-03-17;15(6):.
Species: Human
Sample Types: Cell Culture Supernates

Effects of hypoxia on bronchial and alveolar epithelial cells linked to pathogenesis in chronic lung disorders
Authors: R Berggren-N, M Ryde, A Löfdahl, A Ibáñez-Fon, M Kåredal, G Westergren, E Tufvesson, AK Larsson-Ca
Frontiers in Physiology, 2023-03-13;14(0):1094245.
Species: Human
Sample Types: Cell Culture Supernates

Stromal Vascular Fraction Cells from Individuals Who Have Previously Undergone Radiotherapy Retain Their Pro-Wound Healing Properties
Authors: LV Trevor, K Riches-Sum, AL Mahajan, MJ Thornton
Journal of Clinical Medicine, 2023-03-04;12(5):.
Species: Human
Sample Types: Cell Culture Supernates

Toll-like Receptor 2 Mediates VEGF Overexpression and Mesothelial Hyperpermeability in Tuberculous Pleural Effusion
Authors: WL Chen, KL Lee, KS Lai, JH Tsai, SH Hsiao, CL Chung
International Journal of Molecular Sciences, 2023-02-02;24(3):.
Species: Human
Sample Types: Pleural Fluid

High-Capacity Mesoporous Silica Nanocarriers of siRNA for Applications in Retinal Delivery
Authors: A Ultimo, M Orzaez, MJ Santos-Mar, R Martínez-M, MD Marcos, F Sancenón, E Ruiz-Herná
International Journal of Molecular Sciences, 2023-02-01;24(3):.
Species: Human
Sample Types: Cell Culture Supernates

Towards integration of time-resolved confocal microscopy of a 3D in vitro microfluidic platform with a hybrid multiscale model of tumor angiogenesis
Authors: CM Phillips, EABF Lima, M Gadde, AM Jarrett, MN Rylander, TE Yankeelov
PLoS computational biology, 2023-01-18;19(1):e1009499.
Species: Human
Sample Types: Cell Culture Supernates

Targeting tumor-stroma communication by blocking endothelin-1 receptors sensitizes high-grade serous ovarian cancer to PARP inhibition
Authors: P Tocci, C Roman, R Sestito, V Di Castro, A Sacconi, I Molineris, F Paolini, M Carosi, G Tonon, G Blandino, A Bagnato
Cell Death & Disease, 2023-01-05;14(1):5.
Species: Human
Sample Types: Cell Culture Supernates

VEGF-A165 is the predominant VEGF-A isoform in platelets, while VEGF-A121 is abundant in serum and plasma from healthy individuals
Authors: M Yamakuchi, M Okawa, K Takenouchi, A Bibek, S Yamada, K Inoue, K Higurashi, A Tabaru, K Tanoue, Y Oyama, S Higashi, C Fujisaki, H Kanda, H Terasaki, T Sakamoto, Y Soga, T Hashiguchi
PLoS ONE, 2023;18(4):e0284131.
Species: Human
Sample Types: Serum

L-type calcium channel blocker increases VEGF concentrations in retinal cells and human serum
Authors: A Kumar, S Mutter, EB Parente, V Harjutsalo, R Lithovius, S Mathavan, M Lehto, TP Hiltunen, KK Kontula, PH Groop
PLoS ONE, 2023;18(4):e0284364.
Species: Human
Sample Types: Serum

PARP Inhibitor Inhibits the Vasculogenic Mimicry through a NF-kappaB-PTX3 Axis Signaling in Breast Cancer Cells
Authors: J Chivot, N Ferrand, A Fert, P Van Dreden, R Morichon, M Sabbah
International Journal of Molecular Sciences, 2022-12-18;23(24):.
Species: Human
Sample Types: Cell Culture Supernates

Vitreous protein networks around ANG2 and VEGF in proliferative diabetic retinopathy and the differential effects of aflibercept versus bevacizumab pre-treatment
Authors: I Klaassen, P Avery, RO Schlingema, DHW Steel
Scientific Reports, 2022-12-06;12(1):21062.
Species: Human
Sample Types: Vitreous Humor

MiR-302d inhibits TGFB-induced EMT and promotes MET in primary human RPE cells
Authors: X Hu, M Binter, K Hufendiek, J Tode, C Framme, H Fuchs
PLoS ONE, 2022-11-28;17(11):e0278158.
Species: Human
Sample Types: Cell Culture Supernates

Oncosuppressive miRNAs loaded in lipid nanoparticles potentiate targeted therapies in BRAF-mutant melanoma by inhibiting core escape pathways of resistance
Authors: L Fattore, G Cafaro, M Di Martile, V Campani, A Sacconi, D Liguoro, E Marra, S Bruschini, D Stoppoloni, R Cirombella, F De Nicola, M Pallocca, CF Ruggiero, V Castaldo, A Catizone, D Del Bufalo, G Viglietto, A Vecchione, G Blandino, L Aurisicchi, M Fanciulli, PA Ascierto, G De Rosa, R Mancini, G Ciliberto
Oncogene, 2022-11-23;0(0):1-15.
Species: Human
Sample Types: Cell Culture Supernates

Biomarkers for anti-vascular endothelial growth factor drugs
Authors: S Kuriyama, T Yamada, A Matsuda, G Takahashi, T Iwai, K Takeda, K Ueda, T Miyasaka, Y Yokoyama, S Shinji, H Sonoda, R Ohta, K Yonaga, S Kanaka, H Yoshida
Oncology Letters, 2022-11-07;24(6):463.
Species: Human
Sample Types: Plasma

COX-2/PGE2/VEGF signaling promotes ERK-mediated BMSCs osteogenic differentiation under hypoxia by the paracrine action of ECs
Authors: Y Wu, M Liu, H Zhou, X He, W Shi, Q Yuan, Y Zuo, B Li, Q Hu, Y Xie
Cytokine, 2022-10-07;161(0):156058.
Species: Rat
Sample Types: Cell Culture Supernates

Retinal Pigment Epithelium-Secreted VEGF-A Induces Alpha-2-Macroglobulin Expression in Endothelial Cells
Authors: GL Lehmann, M Ginsberg, DJ Nolan, C Rodríguez, J Martínez-G, S Zeng, AP Voigt, RF Mullins, S Rafii, E Rodriguez-, I Benedicto
Cells, 2022-09-24;11(19):.
Species: Human
Sample Types: Cell Culture Supernates

Upregulation of the oestrogen target gene SIX1 is associated with higher growth speed and decreased survival in HCV-positive women with hepatocellular carcinoma
Authors: RM Critelli, F Milosa, A Romanzi, S Lasagni, G Marcelli, L Di Marco, A Pivetti, F Schepis, D Romagnoli, S Mancarella, F Dituri, ML Martinez-C, G Giannelli, E Villa
Oncology Letters, 2022-09-21;24(5):395.
Species: Human
Sample Types: Serum

Lung Ultrasound Findings and Endothelial Perturbation in a COVID-19 Low-Intensity Care Unit
Authors: R Gualtierot, F Tafuri, R Rossio, M Rota, P Bucciarell, B Ferrari, A Giachi, C Suffritti, M Cugno, F Peyvandi, On Behalf
Journal of Clinical Medicine, 2022-09-15;11(18):.
Species: Human
Sample Types: Serum

Mesenchymal Stem Cell Sheet Centrifuge-Assisted Layering Augments Pro-Regenerative Cytokine Production
Authors: S Bou-Ghanna, K Kim, M Kondo, DW Grainger, T Okano
Cells, 2022-09-12;11(18):.
Species: Human
Sample Types: Cell Culture Supernates

Novel Potency Assay for MSC Secretome-Based Treatment of Idiopathic Male Infertility Employed Leydig Cells and Revealed Vascular Endothelial Growth Factor as a Promising Potency Marker
Authors: A Monakova, G Sagaradze, N Basalova, V Popov, V Balabanyan, A Efimenko
International Journal of Molecular Sciences, 2022-08-20;23(16):.
Species: Human
Sample Types: Cell Culture Supernates

The blunted vascular endothelial growth factor-A (VEGF-A) response to high-altitude hypoxia and genetic variants in the promoter region of the VEGFA gene in Sherpa highlanders
Authors: Y Droma, M Hanaoka, T Kinjo, N Kobayashi, M Yasuo, Y Kitaguchi, M Ota
PeerJ, 2022-08-17;10(0):e13893.
Species: Human
Sample Types: Plasma

Role of Autotaxin in High Glucose-Induced Human ARPE-19 Cells
Authors: Y Liu, R Yamagishi, M Honjo, M Kurano, Y Yatomi, K Igarashi, M Aihara
International Journal of Molecular Sciences, 2022-08-16;23(16):.
Species: Human
Sample Types: Cell Culture Supernates

Further Evidence of Neuroprotective Effects of Recombinant Human Erythropoietin and Growth Hormone in Hypoxic Brain Injury in Neonatal Mice
Authors: S Klepper, S Jung, L Dittmann, CI Geppert, A Hartmann, N Beier, R Trollmann
International Journal of Molecular Sciences, 2022-08-04;23(15):.
Species: Human
Sample Types: Plasma

Oxidative stress differentially impacts apical and basolateral secretion of angiogenic factors from human iPSC-derived retinal pigment epithelium cells
Authors: L Chen, ND Perera, AJ Karoukis, KL Feathers, RR Ali, DA Thompson, AT Fahim
Scientific Reports, 2022-07-26;12(1):12694.
Species: Human
Sample Types: Cell Culture Supernates

Early increase of plasma soluble VEGFR-2 is associated with clinical benefit from second-line treatment of paclitaxel and ramucirumab in advanced gastric cancer
Authors: L Fornaro, G Musettini, P Orlandi, I Pecora, C Vivaldi, M Banchi, F Salani, E Fini, V Massa, S Catanese, F Cucchiara, M Lencioni, G Masi, E Vasile, G Bocci
American journal of cancer research, 2022-07-15;12(7):3347-3356.
Species: Human
Sample Types: Plasma

Serum Concentration of Selected Angiogenesis-Related Molecules Differs among Molecular Subtypes, Body Mass Index and Menopausal Status in Breast Cancer Patients
Authors: D Balalis, D Tsakogiann, E Kalogera, S Kokkali, E Tripodaki, A Ardavanis, D Manatakis, D Dimas, N Koufopoulo, F Fostira, D Korkolis, I Misitzis, N Vassos, C Spiliopoul, D Vlachodimi, G Bletsa, N Arkadopoul
Oncogene, 2022-07-14;11(14):.
Species: Human
Sample Types: Serum

Neutrophils and Circulating Inflammatory Biomarkers in Diabetes Mellitus and Heart Failure With Preserved Ejection Fraction
Authors: D Chaar, BL Dumont, B Vulesevic, PE Neagoe, A Räkel, M White, MG Sirois
The American journal of cardiology, 2022-07-08;0(0):.
Species: Human
Sample Types: Serum

ANGPTL4 influences the therapeutic response of neovascular age-related macular degeneration patients by promoting choroidal neovascularization
Authors: Y Qin, A Dinabandhu, X Cao, JC Sanchez, K Jee, M Rodrigues, C Guo, J Zhang, J Vancel, D Menon, NS Khan, T Ma, SY Tzeng, YJ Daoud, JJ Green, GL Semenza, S Montaner, A Sodhi
JCI Insight, 2022-07-08;0(0):.
Species: Human
Sample Types: Aqueous Humor

Dual STAT?3 and IL?6R inhibition with stattic and tocilizumab decreases migration, invasion and proliferation of prostate cancer cells by targeting the IL?6/IL?6R/STAT?3 axis
Authors: A Méndez-Cle, A Bravo-Cuel, S González-O, M Santiago-M, L Palafox-Ma, L Jave-Suáre, F Solorzano-, M Villaseñor, P Ortiz-Laza, G Hernández-
Oncology reports, 2022-06-15;48(2):.
Species: Human
Sample Types: Cell Culture Supernates

Cholecalciferol supplementation and angiogenic markers in chronic kidney disease
Authors: J Kaur, K Kamboj, AK Yadav, P Kaur, V Kumar, V Jha
PLoS ONE, 2022-06-03;17(6):e0268946.
Species: Human
Sample Types: Serum

Simultaneous Spray Drying for Combination Dry Powder Inhaler Formulations
Authors: KB Shepard, AM Pluntze, DT Vodak
Pharmaceutics, 2022-05-26;14(6):.
Species: Human
Sample Types: Protein

Effect of Manual Therapy Compared to Ibuprofen on Primary Dysmenorrhea in Young Women-Concentration Assessment of C-Reactive Protein, Vascular Endothelial Growth Factor, Prostaglandins and Sex Hormones
Authors: Z Barcikowsk, ME Grzybowska, P W??, M Jaskulak, M Kurpas, M Sotomski, M Starzec-Pr, E Rajkowska-, R Hansdorfer, K Zorena
Journal of Clinical Medicine, 2022-05-10;11(10):.
Species: Human
Sample Types: Serum

Endothelial PRMT5 plays a crucial role in angiogenesis after acute ischemic injury
Authors: Q Ye, J Zhang, C Zhang, B Yi, K Kazama, W Liu, X Sun, Y Liu, J Sun
JCI Insight, 2022-05-09;7(9):.
Species: Human
Sample Types: Cell Culture Supernates

Serum Levels of Stromal Cell-Derived Factor-1alpha and Vascular Endothelial Growth Factor Predict Clinical Outcomes in Head and Neck Squamous Cell Carcinoma Patients Receiving TPF Induction Chemotherapy
Authors: YH Chen, CY Chien, YM Wang, SH Li
Biomedicines, 2022-03-29;10(4):.
Species: Human
Sample Types: Serum

Increased angiogenic factors in the aqueous and vitreous humors after disinsertion of extraocular muscle and the effects of triamcinolone acetate injection
Authors: H Suk-Gyu, B Kang, JS Song
Scientific Reports, 2022-03-28;12(1):5276.
Species: Rabbit
Sample Types: Aqueous Humor

Placental lesions and differential expression of pro-and anti-angiogenic growth mediators and oxidative DNA damage marker in placentae of Ghanaian suboptimal and optimal health status pregnant women who later developed preeclampsia
Authors: EO Anto, DA Coall, EA Asiamah, OO Afriyie, O Addai-Mens, YA Wiafe, W Owiredu, C Obirikoran, ME Annani-Ako, NA Titiloye, E Adua, E Acheampong, EA Adu, S Opoku, AO Anto, A Tawiah, Y Wang, W Wang
PLoS ONE, 2022-03-21;17(3):e0265717.
Species: Human
Sample Types: Plasma

Nectin cell adhesion molecule 4 regulates angiogenesis through Src signaling and serves as a novel therapeutic target in angiosarcoma
Authors: Y Tanaka, M Murata, K Tanegashim, Y Oda, T Ito
Scientific Reports, 2022-03-07;12(1):4031.
Species: Human
Sample Types: Cell Culture Supernates

Molecular Biological Comparison of Dental Pulp- and Apical Papilla-Derived Stem Cells
Authors: M Smeda, KM Galler, M Woelflick, A Rosendahl, C Moehle, B Lenhardt, W Buchalla, M Widbiller
International Journal of Molecular Sciences, 2022-02-27;23(5):.
Species: Human
Sample Types: Cell Culture Supernates

The value of plasma hypoxia markers for predicting imaging-based hypoxia in patients with head-and-neck cancers undergoing definitive chemoradiation
Authors: A Rühle, AL Grosu, N Wiedenmann, J Ruf, B Bieber, R Stoian, AR Thomsen, E Gkika, P Vaupel, D Baltas, WA Weber, M Mix, NH Nicolay
Clinical and translational radiation oncology, 2022-02-21;33(0):120-127.
Species: Human
Sample Types: Plasma

Effect of Revascularization on Intramuscular Vascular Endothelial Growth Factor Levels in Peripheral Arterial Disease
Authors: L Schawe, B Raude, JC Carstens, I Hintersehe, RD Hein, S Omran, G Berger, NA Hering, M Buerger, A Greiner, JP Frese
Biomedicines, 2022-02-17;10(2):.
Species: Human
Sample Types: Cell Lysates

Inhibition of the VEGF signaling pathway attenuates tumor?associated macrophage activity in liver cancer
Authors: S Okikawa, Y Morine, Y Saito, S Yamada, K Tokuda, H Teraoku, K Miyazaki, S Yamashita, T Ikemoto, S Imura, M Shimada
Oncology reports, 2022-02-16;47(4):.
Species: Human
Sample Types: Cell Culture Supernates

Long non-coding RNA PAARH promotes hepatocellular carcinoma progression and angiogenesis via upregulating HOTTIP and activating HIF-1alpha/VEGF signaling
Authors: H Wei, Z Xu, L Chen, Q Wei, Z Huang, G Liu, W Li, J Wang, Q Tang, J Pu
Cell Death & Disease, 2022-02-02;13(2):102.
Species: Human
Sample Types: Cell Culture Supernates

Baseline serum biomarkers of inflammation, bone turnover and adipokines predict spinal radiographic progression in ankylosing spondylitis patients on TNF inhibitor therapy
Authors: J Rademacher, M Siderius, L Gellert, FR Wink, M Verba, F Maas, LM Tietz, D Poddubnyy, A Spoorenber, S Arends
Seminars in arthritis and rheumatism, 2022-02-02;53(0):151974.
Species: Human
Sample Types: Serum

Impact of Chronic Kidney Disease on the Associations of Cardiovascular Biomarkers With Adverse Outcomes in Patients With Suspected or Known Coronary Artery Disease: The EXCEED-J Study
Authors: H Wada, T Shinozaki, M Suzuki, S Sakagami, Y Ajiro, J Funada, M Matsuda, M Shimizu, T Takenaka, Y Morita, K Yonezawa, H Matsubara, Y Ono, T Nakamura, K Fujimoto, A Ninomiya, T Kato, T Unoki, D Takagi, K Wada, M Wada, M Iguchi, H Yamakage, T Kusakabe, A Yasoda, A Shimatsu, K Kotani, N Satoh-Asah, M Abe, M Akao, K Hasegawa, EXCEED?J S
Journal of the American Heart Association, 2022-01-20;11(3):e023464.
Species: Human
Sample Types: Serum

Dubious effects of methadone as an "anticancer" drug on ovarian cancer cell-lines and patient-derived tumor-spheroids
Authors: H Fiegl, J Hagenbuchn, C Kyvelidou, B Seeber, S Sopper, I Tsibulak, V Wieser, E Reiser, J Roessler, K Huhtinen, O Carpén, W Parson, S Sprung, C Marth, MJ Ausserlech, AG Zeimet
Gynecologic oncology, 2022-01-13;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

10Z?Hymenialdisine inhibits angiogenesis by suppressing NF?kappaB activation in pancreatic cancer cell lines
Authors: G Ueda, Y Matsuo, H Murase, Y Aoyama, T Kato, K Omi, Y Hayashi, H Imafuji, K Saito, K Tsuboi, M Morimoto, R Ogawa, H Takahashi, A Mitsui, M Kimura, S Takiguchi
Oncology reports, 2022-01-11;47(3):.
Species: Human
Sample Types: Cell Culture Supernates

BSG (CD147) Serum Level and Genetic Variants Are Associated with Overall Survival in Acute Myeloid Leukaemia
Authors: P ?acina, A Butrym, E Turlej, M Stachowicz, J Wietrzyk, G Mazur, K Bogunia-Ku
Journal of Clinical Medicine, 2022-01-10;11(2):.
Species: Human
Sample Types: Serum

Potential Anti-Metastatic Role of the Novel miR-CT3 in Tumor Angiogenesis and Osteosarcoma Invasion
Authors: L Raimondi, A Gallo, N Cuscino, A De Luca, V Costa, V Carina, D Bellavia, M Bulati, R Alessandro, M Fini, PG Conaldi, G Giavaresi
International Journal of Molecular Sciences, 2022-01-09;23(2):.
Species: Human
Sample Types: Cell Culture Supernates

Plasmatic MMP9 released from tumor-infiltrating neutrophils is predictive for bevacizumab efficacy in glioblastoma patients: an AVAglio ancillary study
Authors: C Jiguet-Jig, S Boissonnea, E Denicolai, V Hein, R Lasseur, J Garcia, S Romain, R Appay, T Graillon, W Mason, AF Carpentier, AA Brandes, L' Ouafik, W Wick, A Baaziz, JP Gigan, RJ Argüello, D Figarella-, O Chinot, E Tabouret
Acta neuropathologica communications, 2022-01-03;10(1):1.
Species: Human
Sample Types: Plasma

Effects of P4 Antagonist RU486 on VEGF and Its Receptors' Signaling during the In Vivo Transition from the Preovulatory to Periovulatory Phase of Ovarian Follicles
Authors: A Mauro, P Berardinel, V Russo, N Bernabò, A Martelli, D Nardinocch, O Di Giacint, M Turriani, B Barboni
International Journal of Molecular Sciences, 2021-12-16;22(24):.
Species: Porcine
Sample Types: Tissue Homogenates

Effects of Intravitreal Aflibercept on the Systemic Insulin-like Growth Factor-I and Vascular Endothelial Growth Factor-A in Patients with Diabetic Retinopathy and Age-Related Macular Degeneration
Authors: AL Huber, R Angermann, Y Nowosielsk, C Seifarth, MT Kralinger, C Zehetner
Journal of Ophthalmology, 2021-12-15;2021(0):7058505.
Species: Human
Sample Types: Plasma

Effect of the Renin-Angiotensin-Aldosterone System Reactivity on Endothelial Function and Modulative Role of Valsartan in Male Subjects with Essential Hypertension
Authors: J Jasiczek, M Trocha, A Derkacz, E Szahidewic, A Doroszko
Journal of Clinical Medicine, 2021-12-13;10(24):.
Species: Human
Sample Types: Plasma

Nano-Sized Extracellular Matrix Particles Lead to Therapeutic Improvement for Cutaneous Wound and Hindlimb Ischemia
Authors: SS Ha, JH Kim, C Savitri, D Choi, K Park
International Journal of Molecular Sciences, 2021-12-09;22(24):.
Species: Human
Sample Types: Cell Culture Supernates

Plasma Levels and Diagnostic Utility of VEGF in a Three-Year Follow-Up of Patients with Breast Cancer
Authors: GE B?dkowska, E Gacuta, M Zbucka-Kr?, P ?awicki, M Szmitkowsk, A Lemancewic, J Motyka, A Kobus, M Chor??y, M Paniczko, S ?awicki
Journal of Clinical Medicine, 2021-11-22;10(22):.
Species: Human
Sample Types: Plasma

Angiogenic factors measured in aspirated placental tissue between the 10?+?6 and 18?+?3 weeks of gestation
Authors: J Sikovanyec, M Vincze, I Földesi, G Németh, Z Kozinszky
Reproductive biology, 2021-11-16;21(4):100572.
Species: Human
Sample Types: Tissue Homogenates

LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy
Authors: P Li, Q Li, N Biswas, H Xin, T Diemer, L Liu, L Perez Guti, G Paternostr, C Piermarocc, S Domanskyi, RK Wang, N Ferrara
Embo Molecular Medicine, 2021-11-15;0(0):e14511.
Species: Human
Sample Types: Cell Culture Supernates

In Vitro Hair Growth Promoting Effect of a Noncrosslinked Hyaluronic Acid in Human Dermal Papilla Cells
Authors: N Zerbinati, S Sommatis, C Maccario, MC Capillo, S Di Frances, R Rauso, M Protasoni, E D'Este, DD Gasperina, R Mocchi
BioMed Research International, 2021-10-31;2021(0):5598110.
Species: Human
Sample Types: Cell Culture Supernates

Inhibition of FABP6 Reduces Tumor Cell Invasion and Angiogenesis through the Decrease in MMP-2 and VEGF in Human Glioblastoma Cells
Authors: FC Pai, HW Huang, YL Tsai, WC Tsai, YC Cheng, HH Chang, Y Chen
Cells, 2021-10-17;10(10):.
Species: Human
Sample Types: Cell Culture Supernates

Analysis focusing on plasma von Willebrand factor in pachychoroid neovasculopathy and age-related macular degeneration
Authors: H Hirai, M Yamashita, M Matsumoto, M Hayakawa, K Sakai, T Ueda, N Ogata
Scientific Reports, 2021-10-07;11(1):19987.
Species: Human
Sample Types: Plasma

Retinal VEGF-A Overexpression Is Not Sufficient to Induce Lymphangiogenesis Regardless of VEGF-C Upregulation and Lyve1+ Macrophage Infiltration
Authors: I Wada, S Nakao, M Yamaguchi, Y Kaizu, M Arima, S Sawa, KH Sonoda
Investigative Ophthalmology & Visual Science, 2021-10-04;62(13):17.
Species: Human
Sample Types: Vitreous Humor

Triamcinolone acetonide modulates TGF?beta2?induced angiogenic and tissue?remodeling effects in cultured human retinal pigment epithelial cells
Authors: CC Hsiao, YC Chang, YT Hsiao, PH Chen, MC Hsieh, WC Wu, YH Kao
Molecular Medicine Reports, 2021-09-15;24(5):.
Species: Human
Sample Types: Cell Culture Supernates

Possible role of HPV/EBV coinfection in anoikis resistance and development in prostate cancer
Authors: JS Nahand, K Khanaliha, H Mirzaei, M Moghoofei, HB Baghi, M Esghaei, AR Khatami, M Fatemipour, F Bokharaei-
BMC Cancer, 2021-08-17;21(1):926.
Species: Human
Sample Types: Serum

CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance
Authors: S Ma, LS Mangala, W Hu, E Bayaktar, A Yokoi, W Hu, S Pradeep, S Lee, PD Piehowski, A Villar-Pra, SY Wu, MH McGuire, OD Lara, C Rodriguez-, CJ LaFargue, NB Jennings, KD Rodland, T Liu, V Kundra, PT Ram, S Ramakrishn, G Lopez-Bere, RL Coleman, AK Sood
Cell Reports, 2021-08-17;36(7):109549.
Species: Human
Sample Types: Cell Lysates

Antitumor effects of bevacizumab in combination with fluoropyrimidine drugs on human oral squamous cell carcinoma
Authors: Y Itashiki, K Harada, T Takenawa, T Ferdous, Y Ueyama, K Mishima
Oncology Letters, 2021-08-11;22(4):730.
Species: Human
Sample Types: Cell Culture Supernates

Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo
Authors: T Mashima, T Wakatsuki, N Kawata, MK Jang, A Nagamori, H Yoshida, K Nakamura, T Migita, H Seimiya, K Yamaguchi
Scientific Reports, 2021-07-23;11(1):15125.
Species: Human
Sample Types: Tissue Homogenates

Adipose-derived mesenchymal stem cells preserve cardiac function via ANT-1 in dilated cardiomyopathy hamster model
Authors: D Mori, S Miyagawa, T Kido, H Hata, T Ueno, K Toda, T Kuratani, M Oota, K Kawai, H Kurata, H Nishida, Y Sawa
Regenerative Therapy, 2021-07-09;18(0):182-190.
Species: Human
Sample Types: Cell Culture Supernates

CD146/Soluble CD146 Pathway Is a Novel Biomarker of Angiogenesis and Inflammation in Proliferative Diabetic Retinopathy
Authors: AM Abu El-Asr, MI Nawaz, A Ahmad, MM Siddiquei, E Allegaert, PW Gikandi, G De Hertogh, G Opdenakker
Investigative Ophthalmology & Visual Science, 2021-07-01;62(9):32.
Species: Human
Sample Types: Cell Culture Supernates

Vascular endothelial growth factor concentrations in the cerebrospinal fluid of dogs with neoplastic or inflammatory central nervous system disorders
Authors: CL Mariani, ZE Niman, LB Boozer, LK Ruterborie, PJ Early, KR Muñana, NJ Olby
Journal of veterinary internal medicine, 2021-06-09;0(0):.
Species: Human
Sample Types: Serum

JunB is a key regulator of multiple myeloma bone marrow angiogenesis
Authors: F Fan, S Malvestiti, S Vallet, J Lind, JM Garcia-Man, E Morelli, Q Jiang, A Seckinger, D Hose, H Goldschmid, A Stadlbauer, C Sun, H Mei, M Pecherstor, L Bakiri, EF Wagner, G Tonon, M Sattler, Y Hu, P Tassone, D Jaeger, K Podar
Leukemia, 2021-05-18;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Residual alterations of cardiac and endothelial function in patients who recovered from Takotsubo cardiomyopathy
Authors: L Zilberman, A Zalik, I Fugenfirov, S Shimoni, J George, S Goland
Clinical cardiology, 2021-05-06;0(0):.
Species: Human
Sample Types: Serum

Interleukin-36&alpha suppresses growth of non-small cell lung cancer in vitro by reducing angiogenesis
Authors: X Xie, H Hu, J He, Y Liu, F Guo, F Luo, M Jiang, L Wang
FEBS Open Bio, 2021-05-02;11(5):1353-1363.
Species: Human
Sample Types: Cell Culture Supernates

Defined MSC exosome with high yield and purity to improve regenerative activity
Authors: JY Kim, WK Rhim, YI Yoo, DS Kim, KW Ko, Y Heo, CG Park, DK Han
Journal of tissue engineering, 2021-04-20;12(0):2041731421100.
Species: Human
Sample Types: Cell Lysates

Myeloid-resident neuropilin-1 promotes choroidal neovascularization while mitigating inflammation
Authors: EMMA Andriessen, F Binet, F Fournier, M Hata, A Dejda, G Mawambo, S Crespo-Gar, F Pilon, M Buscarlet, K Beauchemin, V Bougie, G Cumberlidg, AM Wilson, S Bourgault, FA Rezende, N Beaulieu, JS Delisle, P Sapieha
Embo Molecular Medicine, 2021-04-19;0(0):e11754.
Species: Human
Sample Types: Vitreous Humor

3D cell sheet structure augments mesenchymal stem cell cytokine production
Authors: S Bou-Ghanna, K Kim, DW Grainger, T Okano
Scientific Reports, 2021-04-14;11(1):8170.
Species: Human
Sample Types: Cell Culture Supernates

Endurance Training Depletes Antioxidant System but Does Not Affect Endothelial Functions in Women with Abdominal Obesity: A Randomized Trial with a Comparison to Endurance-Strength Training
Authors: M Jamka, P Bogda?ski, P Krzy?anows, A Mi?kiewicz, J Karolkiewi, M Du?-?uchow, R M?dry, A Lisowska, A Gotz-Wi?ck, S Iskakova, J Walkowiak, E M?dry
Journal of Clinical Medicine, 2021-04-12;10(8):.
Species: Human
Sample Types: Whole Blood

Interleukin-6 as an enhancer of anti-angiogenic therapy for ovarian clear cell carcinoma
Authors: T Seki, N Yanaihara, JS Shapiro, M Saito, J Tabata, R Yokomizo, D Noguchi, T Kuroda, A Kawabata, J Suzuki, K Takahashi, H Matsuzawa, M Miyake, M Takenaka, Y Iida, S Yanagida, A Okamoto
Scientific Reports, 2021-04-08;11(1):7689.
Species: Human
Sample Types: Cell Culture Supernates

Exosomes Secreted from Hypoxia-Preconditioned Mesenchymal Stem Cells Prevent Steroid-Induced Osteonecrosis of the Femoral Head by Promoting Angiogenesis in Rats
Authors: N Yuan, Z Ge, W Ji, J Li
BioMed Research International, 2021-04-07;2021(0):6655225.
Species: Human
Sample Types: Cell Culture Supernates

Probiotic-Derived Polyphosphate Accelerates Intestinal Epithelia Wound Healing through Inducing Platelet-Derived Mediators
Authors: S Isozaki, H Konishi, M Fujiya, H Tanaka, Y Murakami, S Kashima, K Ando, N Ueno, K Moriichi, T Okumura
Mediators of Inflammation, 2021-03-29;2021(0):5582943.
Species: Human
Sample Types: Plasma

3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration
Authors: KV Manian, CA Galloway, S Dalvi, AA Emanuel, JA Mereness, W Black, L Winschel, C Soto, Y Li, Y Song, W DeMaria, A Kumar, I Slukvin, MP Schwartz, WL Murphy, B Anand-Apte, M Chung, DSW Benoit, R Singh
Cell Stem Cell, 2021-03-29;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

In Ovarian Cancer Multicellular Spheroids, Platelet Releasate Promotes Growth, Expansion of ALDH+ and CD133+ Cancer Stem Cells, and Protection against the Cytotoxic Effects of Cisplatin, Carboplatin and Paclitaxel
Authors: N Casagrande, C Borghese, F Agostini, C Durante, M Mazzucato, A Colombatti, D Aldinucci
International Journal of Molecular Sciences, 2021-03-16;22(6):.
Species: Human
Sample Types: Plasma

Apelin promotes blood and lymph vessel formation and the growth of melanoma lung metastasis
Authors: J Berta, S Török, J Tárnoki-Zá, O Drozdovszk, J Tóvári, S Paku, I Kovács, A Czirók, B Masri, Z Megyesfalv, H Oskolás, J Malm, C Ingvar, G Markó-Varg, B Döme, V László
Scientific Reports, 2021-03-11;11(1):5798.
Species: Human
Sample Types: Plasma

Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis
Authors: D Gan, W Cheng, L Ke, AR Sun, Q Jia, J Chen, J Lin, J Li, Z Xu, P Zhang
Frontiers in Pharmacology, 2021-03-05;12(0):631891.
Species: Rat
Sample Types: Cell Culture Supernates

15-Deoxy-&delta12,14-prostaglandin J2 Upregulates VEGF Expression via NRF2 and Heme Oxygenase-1 in Human Breast Cancer Cells
Authors: EH Kim, SJ Kim, HK Na, W Han, NJ Kim, YG Suh, YJ Surh
Cells, 2021-03-02;10(3):.
Species: Human
Sample Types: Cell Culture Supernates

The psychoactive drug of abuse mephedrone differentially disrupts blood-brain barrier properties
Authors: TP Buzhdygan, CR Rodrigues, HM McGary, JA Khan, AM Andrews, SM Rawls, SH Ramirez
Journal of Neuroinflammation, 2021-03-01;18(1):63.
Species: Human
Sample Types: Cell Culture Supernates

Epigenetic Regulation of Processes Related to High Level of Fibroblast Growth Factor 21 in Obese Subjects
Authors: T P?atek, A Polus, J Góralska, U Ra?ny, A Dziewo?ska, A Micek, A Dembi?ska-, B Solnica, M Malczewska
Genes, 2021-02-21;12(2):.
Species: Human
Sample Types: Serum

Expansion and characterization of bone marrow derived human mesenchymal stromal cells in serum-free conditions
Authors: S Bhat, P Viswanatha, S Chandanala, SJ Prasanna, RN Seetharam
Scientific Reports, 2021-02-09;11(1):3403.
Species: Human
Sample Types: Cell Culture Supernates

Syndecan-1 Overexpressing Mesothelioma Cells Inhibit Proliferation, Wound Healing, and Tube Formation of Endothelial Cells
Authors: J Javadi, G Heidari-Ha, A Schmalzl, T Szatmári, M Metintas, P Aspenström, A Hjerpe, K Dobra
Cancers, 2021-02-06;13(4):.
Species: Human
Sample Types: Cell Culture Supernates

The ER stress response mediator ERO1 triggers cancer metastasis by favoring the angiogenic switch in hypoxic conditions
Authors: E Varone, A Decio, A Chernoruds, L Minoli, L Brunelli, F Ioli, A Piotti, R Pastorelli, M Fratelli, M Gobbi, R Giavazzi, E Zito
Oncogene, 2021-02-02;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Crosstalk between Mast Cells and Lung Fibroblasts Is Modified by Alveolar Extracellular Matrix and Influences Epithelial Migration
Authors: M Bagher, O Rosmark, L Elowsson R, A Nybom, S Wasserstro, C Müller, XH Zhou, G Dellgren, O Hallgren, L Bjermer, AK Larsson-Ca, G Westergren
International Journal of Molecular Sciences, 2021-01-06;22(2):.
Species: Human
Sample Types: Cell Culture Supernates

Significantly high concentrations of vascular endothelial growth factor in chronic subdural hematoma with trabecular formation
Authors: J Takei, T Tanaka, Y Yamamoto, K Hatano, D Ichinose, F Maruyama, S Tochigi, Y Hasegawa, Y Murayama
Clinical neurology and neurosurgery, 2021-01-06;202(0):106458.
Species: Human
Sample Types: Hematoma Fluid

Adaptive response triggered by the repeated SCUBA diving is reflected in cardiovascular, muscular, and immune biomarkers
Authors: M Žarak, A Perovi?, M Njire Brat, S Šupraha Go, J Dumi?
Physiological Reports, 2021-01-01;9(2):e14691.
Species: Human
Sample Types: Plasma

Long Noncoding RNA SNHG12 Promotes Prostate Tumor Occurrence and Progression via AKT Regulation
Authors: Z Chen, T Qi, XP Qin, J Wang, ZS Huang, XY Hu, G Chen, LJ Qu, YM Zhuo
BioMed Research International, 2020-12-22;2020(0):8812923.
Species: Human
Sample Types: Cell Culture Supernates

Therapeutic Angiogenesis by a "Dynamic Duo": Simultaneous Expression of HGF and VEGF165 by Novel Bicistronic Plasmid Restores Blood Flow in Ischemic Skeletal Muscle
Authors: E Slobodkina, M Boldyreva, M Karagyaur, R Eremichev, N Alexandrus, V Balabanyan, Z Akopyan, Y Parfyonova, V Tkachuk, P Makarevich
Pharmaceutics, 2020-12-18;12(12):.
Species: Human
Sample Types: Cell Culture Supernates

Vanucizumab mode of action: Serial biomarkers in plasma, tumor, and skin-wound-healing biopsies
Authors: F Heil, G Babitzki, A Julien-Laf, CH Ooi, M Hidalgo, C Massard, M Martinez-G, C Le Tournea, M Kockx, P Gerber, S Rossomanno, O Krieter, A Lahr, N Wild, SV Harring, K Lechner
Translational Oncology, 2020-12-15;14(2):100984.
Species: Human
Sample Types: Plasma

Quercetin Induces Apoptosis via Downregulation of Vascular Endothelial Growth Factor/Akt Signaling Pathway in Acute Myeloid Leukemia Cells
Authors: H Shi, XY Li, Y Chen, X Zhang, Y Wu, ZX Wang, PH Chen, HQ Dai, J Feng, S Chatterjee, ZJ Li, XW Huang, HQ Wei, J Wang, GD Lu, J Zhou
Frontiers in Pharmacology, 2020-12-10;11(0):534171.
Species: Human
Sample Types: Cell Culture Supernates

The inhibitory effect of TU-100 on hepatic stellate cell activation in the tumor microenvironment
Authors: Y Wada, K Tokuda, Y Morine, S Okikawa, S Yamashita, T Ikemoto, S Imura, Y Saito, S Yamada, M Shimada
Oncotarget, 2020-12-08;11(49):4593-4604.
Species: Human
Sample Types: Cell Culture Supernates

Association between continuous decrease of plasma VEGF-A levels and the efficacy of chemotherapy in combination with anti-programmed cell death 1 antibody in non-small cell lung cancer patients
Authors: T Tozuka, N Yanagitani, H Sakamoto, H Yoshida, Y Amino, S Uematsu, T Yoshizawa, T Hasegawa, R Ariyasu, K Uchibori, S Kitazono, M Seike, A Gemma, M Nishio
Cancer Treat Res Commun, 2020-11-21;25(0):100249.
Species: Human
Sample Types: Plasma

Hyperoxia sensitizes hypoxic HeLa cells to ionizing radiation by downregulating HIF?1&alpha and VEGF expression
Authors: D Dong, Y Fu, F Chen, J Zhang, H Jia, J Li, H Wang, J Wen
Mol Med Rep, 2020-11-20;23(1):.
Species: Human
Sample Types: Cell Culture Supernates

Matrix Metalloproteinases MMP-2 and MMP-9, Their Inhibitors TIMP-1 and TIMP-2, Vascular Endothelial Growth Factor and sVEGFR-2 as Predictive Markers of Ischemic Retinopathy in Patients with Systemic Sclerosis-Case Series Report
Authors: A Waszczykow, M Podgórski, M Waszczykow, Z Gerlicz-Ko, P Jurowski
Int J Mol Sci, 2020-11-18;21(22):.
Species: Human
Sample Types: Serum

Prognosis of metastasis based on age and serum analytes after follow-up of non-metastatic lung cancer patients
Authors: MMS Balla, S Patwardhan, PK Melwani, P Purwar, A Kumar, CS Pramesh, S Laskar, BN Pandey
Transl Oncol, 2020-11-11;14(1):100933.
Species: Human
Sample Types: Serum

Characterisation of osteogenic and vascular responses of hMSCs to Ti-Co doped phosphate glass microspheres using a microfluidic perfusion platform
Authors: C Peticone, DS Thompson, N Dimov, B Jevans, N Glass, M Micheletti, JC Knowles, HW Kim, JJ Cooper-Whi, IB Wall
Journal of tissue engineering, 2020-10-24;11(0):2041731420954.
Species: Human
Sample Types: Cell Culture Supernates

NGF/TRKA Decrease miR-145-5p Levels in Epithelial Ovarian Cancer Cells
Authors: MP Garrido, I Torres, A Avila, J Chnaiderma, M Valenzuela, J Aramburo, L Oróstica, E Durán-Jara, L Lobos-Gonz, C Romero
Int J Mol Sci, 2020-10-16;21(20):.
Species: Human
Sample Types: Cell Culture Supernates

Patient-Derived, Drug-Resistant Colon Cancer Cells Evade Chemotherapeutic Drug Effects via the Induction of Epithelial-Mesenchymal Transition-Mediated Angiogenesis
Authors: JH Lim, KH Choi, SY Kim, CS Park, SM Kim, KC Park
Int J Mol Sci, 2020-10-10;21(20):.
Species: Human
Sample Types: Cell Culture Supernates

Higher level of acute serum VEGF and larger infarct volume are more frequently associated with post-stroke cognitive impairment
Authors: A Prodjohard, AN Vidyanti, NA Susianti, Sudarmanta, S Sutarni, I Setyoprano
PLoS ONE, 2020-10-05;15(10):e0239370.
Species: Human
Sample Types: Plasma

Effects of Moderate Combined Resistance- and Aerobic-Exercise for 12 Weeks on Body Composition, Cardiometabolic Risk Factors, Blood Pressure, Arterial Stiffness, and Physical Functions, among Obese Older Men: A Pilot Study
Authors: W Park, WS Jung, K Hong, YY Kim, SW Kim, HY Park
Int J Environ Res Public Health, 2020-10-03;17(19):.
Species: Human
Sample Types: Serum

Clinical value of selected markers of angiogenesis, inflammation, insulin resistance and obesity in type 1 endometrial cancer
Authors: KM Terlikowsk, B Dobrzycka, R Terlikowsk, A Sienkiewic, M Kinalski, SJ Terlikowsk
BMC Cancer, 2020-09-25;20(1):921.
Species: Human
Sample Types: Serum

MARTX Toxin-Stimulated Interplay between Human Cells and Vibrio vulnificus
Authors: BS Kim, JH Kim, S Choi, S Park, EY Lee, S Koh, CM Ryu, SY Kim, MH Kim
mSphere, 2020-08-12;5(4):.
Species: Human
Sample Types: Cell Culture Supernates

Exhaled Biomarkers in Idiopathic Pulmonary Fibrosis-A Six-Month Follow-Up Study in Patients Treated with Pirfenidone
Authors: K Jaskiewicz, K Mycroft, M Maskey-War, K Paralusz, N Siemiez, P Nejman-Gry, M Barnas, R Krenke, K Gorska
J Clin Med, 2020-08-05;9(8):.
Species: Human
Sample Types: EBC, Exhaled Breath Condensate (EBC)

Serum vascular endothelial growth factor as a biomarker for prognosis of minor ischemic stroke
Authors: Y Zhang, T Ma, H Hu, J Wang, S Zhou
Clin Neurol Neurosurg, 2020-07-01;196(0):106060.
Species: Human
Sample Types: Serum

Renal cell tumors convert natural killer cells to a proangiogenic phenotype
Authors: Y Guan, CB Chambers, T Tabatabai, H Hatley, KR Delfino, K Robinson, SR Alanee, S Ran, DS Torry, A Wilber
Oncotarget, 2020-06-30;11(26):2571-2585.
Species: Human
Sample Types: Cell Culture Supernates

Divergent Impact of Breast Cancer Laterality on Clinicopathological, Angiogenic, and Hemostatic Profiles: A Potential Role of Tumor Localization in Future Outcomes
Authors: RC Barbara, R Piotr, B Kornel, Z El?bieta, R Danuta, N Eduardo
J Clin Med, 2020-06-02;9(6):.
Species: Human
Sample Types: Plasma

Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth
Authors: HA Oh, J Kwak, BJ Kim, HJ Jin, WS Park, SJ Choi, W Oh, S Um
Cells, 2020-05-28;9(6):.
Species: Human
Sample Types: Cell Culture Supernates

Pharmacogenetics in Model-Based Optimization of Bevacizumab Therapy for Metastatic Colorectal Cancer
Authors: A Papachrist, E Karatza, H Kalofonos, G Sivolapenk
Int J Mol Sci, 2020-05-26;21(11):.
Species: Human
Sample Types: Serum

Supervillin promotes tumor angiogenesis in liver cancer
Authors: C Zhao, Z Zhao, Z Wang, L Hu, H Wang, Z Fang
Oncol. Rep., 2020-05-25;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Effects of FTMT Expression by Retinal Pigment Epithelial Cells on Features of Angiogenesis
Authors: U Buyandelge, DG Walker, D Yanagisawa, T Morimura, I Tooyama
Int J Mol Sci, 2020-05-21;21(10):.
Species: Human
Sample Types: Cell Culture Supernates

Effect of Chemically Induced Hypoxia on Osteogenic and Angiogenic Differentiation of Bone Marrow Mesenchymal Stem Cells and Human Umbilical Vein Endothelial Cells in Direct Coculture
Authors: VT Nguyen, B Canciani, F Cirillo, L Anastasia, GM Peretti, L Mangiavini
Cells, 2020-03-19;9(3):.
Species: Human
Sample Types: Cell Culture Supernates

In Vitro Biophysical and Biological Characterization of Lipid Nanoparticles Co-Encapsulating Oncosuppressors miR-199b-5p and miR-204-5p as Potentiators of Target Therapy in Metastatic Melanoma
Authors: L Fattore, V Campani, CF Ruggiero, V Salvati, D Liguoro, L Scotti, G Botti, PA Ascierto, R Mancini, G De Rosa, G Ciliberto
Int J Mol Sci, 2020-03-12;21(6):.
Species: Human
Sample Types: Cell Culture Supernates

Aqueous humour proteins and treatment outcomes of anti-VEGF therapy in neovascular age-related macular degeneration
Authors: Y Arai, H Takahashi, S Inoda, X Tan, S Sakamoto, Y Inoue, Y Fujino, H Kawashima, Y Yanagi
PLoS ONE, 2020-03-10;15(3):e0229342.
Species: Human
Sample Types: Aqueous Humor

RRM2 elicits the metastatic potential of breast cancer cells by regulating cell invasion, migration and VEGF expression via the PI3K/AKT signaling
Authors: S Zhuang, L Li, Y Zang, G Li, F Wang
Oncol Lett, 2020-03-03;19(4):3349-3355.
Species: Human
Sample Types: Cell Culture Supernates

Protease-activated receptor-2 accelerates intestinal tumor formation through activation of nuclear factor-&kappaB signaling and tumor angiogenesis in ApcMin/+ mice
Authors: M Kawaguchi, K Yamamoto, H Kataoka, A Izumi, F Yamashita, T Kiwaki, T Nishida, E Camerer, T Fukushima
Cancer Sci., 2020-02-24;111(4):1193-1202.
Species: Human
Sample Types: Cell Culture Superantes

Predictive Value of Soluble PD-1, PD-L1, VEGFA, CD40 Ligand and CD44 for Nivolumab Therapy in Advanced Non-Small Cell Lung Cancer: A Case-Control Study
Authors: M Tiako Meyo, A Jouinot, E Giroux-Lep, E Fabre, M Wislez, M Alifano, K Leroy, P Boudou-Rou, C Tlemsani, N Khoudour, J Arrondeau, A Thomas-Sch, H Blons, A Mansuet-Lu, D Damotte, M Vidal, F Goldwasser, J Alexandre, B Blanchet
Cancers (Basel), 2020-02-18;12(2):.
Species: Human
Sample Types: Plasma

Dynamics of Early Signalling Events during Fracture Healing and Potential Serum Biomarkers of Fracture Non-Union in Humans
Authors: AN Burska, PV Giannoudis, BH Tan, D Ilas, E Jones, F Ponchel
J Clin Med, 2020-02-11;9(2):.
Species: Human
Sample Types: Serum

Angiogenic Effects of Human Dental Pulp and Bone Marrow-Derived Mesenchymal Stromal Cells and their Extracellular Vesicles
Authors: G Merckx, B Hosseinkha, S Kuypers, S Deville, J Irobi, I Nelissen, L Michiels, I Lambrichts, A Bronckaers
Cells, 2020-01-28;9(2):.
Species: Human
Sample Types: Serum

The effect of prednisolone on endometrial VGEF concentrations, Gene polymorphisms and pregnancy outcome in women with polycystic ovary syndrome: A retrospective cohort study
Authors: H Bi, FM Aldakheel, M Sawsan Alo
J. Reprod. Immunol., 2020-01-15;137(0):103081.
Species: Human
Sample Types: Serum

Co-cultured spheroids of human periodontal ligament mesenchymal stem cells and vascular endothelial cells enhance periodontal tissue regeneration
Authors: K Sano, M Usui, Y Moritani, K Nakazawa, T Hanatani, H Kondo, M Nakatomi, S Onizuka, T Iwata, T Sato, A Togari, W Ariyoshi, T Nishihara, K Nakashima
Regen Ther, 2020-01-14;14(0):59-71.
Species: Human
Sample Types: Cell Culture Supernates

Castration-induced stromal remodeling disrupts the reconstituted prostate epithelial structure
Authors: S Kajiwara, K Ishii, T Sasaki, M Kato, K Nishikawa, H Kanda, K Arima, M Watanabe, Y Sugimura
Lab. Invest., 2019-12-19;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

PEG grafted chitosan scaffold for dual growth factor delivery for enhanced wound healing
Authors: A Vijayan, S A, GSV Kumar
Sci Rep, 2019-12-16;9(1):19165.
Species: Human
Sample Types: Hydrogel Supernates

Neurocognition and social cognition in remitted first-episode schizophrenia: correlation with VEGF serum levels
Authors: Y Zhao, W Xiao, K Chen, Q Zhan, F Ye, X Tang, X Zhang
BMC Psychiatry, 2019-12-16;19(1):403.
Species: Human
Sample Types: Serum

Exosomes from conditioned media of bone marrow-derived mesenchymal stem cells promote bone regeneration by enhancing angiogenesis
Authors: R Takeuchi, W Katagiri, S Endo, T Kobayashi
PLoS ONE, 2019-11-21;14(11):e0225472.
Species: Human
Sample Types: Cell Culture Supernates

A novel therapeutic approach using peripheral blood mononuclear cells preconditioned by oxygen-glucose deprivation
Authors: M Hatakeyama, M Kanazawa, I Ninomiya, K Omae, Y Kimura, T Takahashi, O Onodera, M Fukushima, T Shimohata
Sci Rep, 2019-11-14;9(1):16819.
Species: Human
Sample Types: Cell Culture Supernates

Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering
Authors: D Hao, C He, B Ma, L Lankford, L Reynaga, DL Farmer, F Guo, A Wang
Stem Cells Int, 2019-11-12;2019(0):9695239.
Species: Human
Sample Types: Cell Culture Supernates

Colorectal cancer cells differentially impact migration and microRNA expression in endothelial cells
Authors: DY Kim, SS Lee, YK Bae
Oncol Lett, 2019-11-05;18(6):6361-6370.
Species: Human
Sample Types: Cell Culture Supernates

Non-proteolytic calpain-6 interacts with VEGFA and promotes angiogenesis by increasing VEGF secretion
Authors: M Oh, SB Rho, C Son, K Park, SY Song
Sci Rep, 2019-10-31;9(1):15771.
Species: Human
Sample Types: Whole Cells

Patient-Specific iPSC Model of a Genetic Vascular Dementia Syndrome Reveals Failure of Mural Cells to Stabilize Capillary Structures
Authors: J Kelleher, A Dickinson, S Cain, Y Hu, N Bates, A Harvey, J Ren, W Zhang, FC Moreton, KW Muir, C Ward, RM Touyz, P Sharma, Q Xu, SJ Kimber, T Wang
Stem Cell Reports, 2019-10-31;13(5):817-831.
Species: Human
Sample Types: Cell Culture Supernates

Blue-violet light decreases VEGFa production in an in vitro model of AMD
Authors: M Marie, P Gondouin, D Pagan, C Barrau, T Villette, J Sahel, S Picaud
PLoS ONE, 2019-10-23;14(10):e0223839.
Species: Porcine
Sample Types: Cell Culture Supernates

VWF/ADAMTS13 ratio as a potential biomarker for early detection of hepatocellular carcinoma
Authors: H Takaya, T Namisaki, M Kitade, K Kaji, K Nakanishi, Y Tsuji, N Shimozato, K Moriya, K Seki, Y Sawada, S Saikawa, S Sato, H Kawaratani, T Akahane, R Noguchi, M Matsumoto, H Yoshiji
BMC Gastroenterol, 2019-10-21;19(1):167.
Species: Human
Sample Types: Serum

Overexpression of Limb-Bud and Heart (LBH) promotes angiogenesis in human glioma via VEGFA-mediated ERK signalling under hypoxia
Authors: Y Jiang, J Zhou, D Zou, D Hou, H Zhang, J Zhao, L Li, J Hu, Y Zhang, Z Jing
EBioMedicine, 2019-10-17;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Hydroxytyrosol Modulates Adipocyte Gene and miRNA Expression Under Inflammatory Condition
Authors: E Scoditti, S Carpi, M Massaro, M Pellegrino, B Polini, MA Carluccio, M Wabitsch, T Verri, P Nieri, R De Caterin
Nutrients, 2019-10-17;11(10):.
Species: Human
Sample Types: Cell Culture Supernates

Ionizing radiation increases the endothelial permeability and the transendothelial migration of tumor cells through ADAM10-activation and subsequent degradation of VE-cadherin
Authors: PN Kouam, GA Rezniczek, IA Adamietz, H Bühler
BMC Cancer, 2019-10-16;19(1):958.
Species: Human
Sample Types: Cell Culture Supernates

Beta-blockers exert potent anti-tumor effects in cutaneous and uveal melanoma
Authors: P Bustamante, D Miyamoto, A Goyeneche, PG de Alba Gr, E Jin, T Tsering, AB Dias, MN Burnier, JV Burnier
Cancer Med, 2019-10-07;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Molecular Basis of The Retinal Pigment Epithelial Changes That Characterize The Ocular Lesion in Toxoplasmosis
Authors: S Lie, BR Vieira, S Arruda, M Simões, LM Ashander, JM Furtado, JR Smith
Microorganisms, 2019-09-29;7(10):.
Species: Human
Sample Types: Cell Culture Supernates

Effects of Sulfated Fucans from Laminaria hyperborea Regarding VEGF Secretion, Cell Viability, and Oxidative Stress and Correlation with Molecular Weight
Authors: P Dörschmann, G Kopplin, J Roider, A Klettner
Mar Drugs, 2019-09-25;17(10):.
Species: Porcine
Sample Types: Cell Culture Supernates

Bioinspired Self-assembling Peptide Hydrogel with Proteoglycan-assisted Growth Factor Delivery for Therapeutic Angiogenesis
Authors: LC Huang, HC Wang, LH Chen, CY Ho, PH Hsieh, MY Huang, HC Wu, TW Wang
Theranostics, 2019-09-21;9(23):7072-7087.
Species: Human
Sample Types: Hydrogel Supernates

Effect of lipopolysaccharide on cell proliferation and vascular endothelial growth factor secretion of periodontal ligament stem cells
Authors: JY Keong, LW Low, JM Chong, YY Ong, SJ Pulikkotil, G Singh, V Nagendraba, SR Banavar, SP Khoo
Saudi Dent J, 2019-08-23;32(3):148-154.
Species: Human
Sample Types: Cell Culture Supernates

LIPUS vs. reaming in non-union treatment: Cytokine expression course as a tool for evaluation and differentiation of non-union therapy
Authors: J Doll, A Moghaddam, V Daniel, B Biglari, R Heller, G Schmidmaie, TF Raven
J Orthop, 2019-08-13;17(0):208-214.
Species: Human
Sample Types: Serum

Multilevel defects in the hematopoietic niche in essential thrombocythemia
Authors: T Sun, M Ju, X Dai, H Dong, W Gu, Y Gao, R Fu, X Liu, Y Huang, W Liu, Y Chi, W Wang, H Li, Y Zhou, L Shi, R Yang, L Zhang
Haematologica, 2019-07-09;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1) is associated with bevacizumab resistance in colorectal cancer via regulation of vascular endothelial growth factor A
Authors: E Burgermeis, F Battaglin, F Eladly, W Wu, F Herweck, N Schulte, J Betge, N Härtel, JN Kather, CA Weis, T Gaiser, A Marx, C Weiss, R Hofheinz, IS Miller, F Loupakis, HJ Lenz, AT Byrne, MP Ebert
EBioMedicine, 2019-07-09;45(0):139-154.
Species: Human
Sample Types: Cell Culture Supernates

Circulating pro- and anti-angiogenic factors in multi-stage liver disease and hepatocellular carcinoma progression
Authors: YY Joo, JW Jang, SW Lee, SH Yoo, JH Kwon, SW Nam, SH Bae, JY Choi, SK Yoon
Sci Rep, 2019-06-24;9(1):9137.
Species: Human
Sample Types: Serum

Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy
Authors: I Uribesalgo, D Hoffmann, Y Zhang, A Kavirayani, J Lazovic, J Berta, M Novatchkov, TP Pai, RA Wimmer, V László, D Schramek, R Karim, L Tortola, S Deswal, L Haas, J Zuber, M Sz?cs, K Kuba, B Dome, Y Cao, BJ Haubner, JM Penninger
EMBO Mol Med, 2019-06-24;0(0):e9266.
Species: Human
Sample Types: Serum

Systemic Inflammation Precedes Microalbuminuria in Diabetes
Authors: FG Scurt, J Menne, S Brandt, A Bernhardt, PR Mertens, H Haller, C Chatzikyrk
Kidney Int Rep, 2019-06-21;4(10):1373-1386.
Species: Human
Sample Types: Serum

Extracellular lipid loading augments hypoxic paracrine signaling and promotes glioma angiogenesis and macrophage infiltration
Authors: S Offer, JA Menard, JE Pérez, KG de Oliveir, VI Chandran, MC Johansson, A Bång-Ruden, P Siesjö, A Ebbesson, I Hedenfalk, PC Sundgren, A Darabi, M Belting
J. Exp. Clin. Cancer Res., 2019-06-07;38(1):241.
Species: Human
Sample Types: Cell Culture Supernates

Longitudinal Changes of PAI-1, MMP-2, and VEGF in Peritoneal Effluents and Their Associations with Peritoneal Small-Solute Transfer Rate in New Peritoneal Dialysis Patients
Authors: N Hao, TT Chiou, CH Wu, YY Lei, PL Liang, MC Chao, H Yang, JB Chen
Biomed Res Int, 2019-05-05;2019(0):2152584.
Species: Human
Sample Types: Peritoneal Fluid

Plasma levels of M-CSF and VEGF in laboratory diagnostics and differentiation of selected histological types of cervical cancers
Authors: I Sidorkiewi, M Zbucka-Kr?, K Zar?ba, E Lubowicka, M Zajkowska, M Szmitkowsk, E Gacuta, S ?awicki
BMC Cancer, 2019-04-29;19(1):398.
Species: Human
Sample Types: Plasma

TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment
Authors: P Zizza, R Dinami, M Porru, C Cingolani, E Salvati, A Rizzo, C D'Angelo, E Petti, CA Amoreo, M Mottolese, I Sperduti, A Chambery, R Russo, P Ostano, G Chiorino, G Blandino, A Sacconi, J Cherfils-V, C Leonetti, E Gilson, A Biroccio
Nucleic Acids Res., 2019-04-23;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Distribution and Activity of Lenvatinib in Brain Tumor Models of Human Anaplastic Thyroid Cancer Cells in Severe Combined Immune Deficient Mice
Authors: R Wang, T Yamada, S Arai, K Fukuda, H Taniguchi, A Tanimoto, A Nishiyama, S Takeuchi, K Yamashita, K Ohtsubo, J Matsui, N Onoda, E Hirata, S Taira, S Yano
Mol. Cancer Ther., 2019-03-29;18(5):947-956.
Species: Human
Sample Types: Cell Culture Supernates

In-vitro binding analysis of anti-human vascular endothelial growth factor antibodies bevacizumab and aflibercept with canine, feline, and equine vascular endothelial growth factor
Authors: LM Muellerlei, B Buxbaum, B Nell, DA Fux
Res. Vet. Sci., 2019-03-22;124(0):233-238.
Species: Human
Sample Types: Recombinant Protein

Spatiotemporal release of VEGF from biodegradable polylactic-co-glycolic acid microspheres induces angiogenesis in chick chorionic allantoic membrane assay
Authors: O Qutachi, AJ Bullock, G Gigliobian, S MacNeil
Int J Pharm, 2019-03-08;561(0):236-243.
Species: Human
Sample Types: Beads

OVA66 promotes tumour angiogenesis and progression through enhancing autocrine VEGF-VEGFR2 signalling
Authors: F Song, Q Chen, W Rao, R Zhang, Y Wang, H Ge, Q Wei
EBioMedicine, 2019-03-01;41(0):156-166.
Species: Human
Sample Types: Cell Culture Supernates

Anti-angiogenic efficacy in invasive breast carcinoma patients depends on clinicopathological determinants
Authors: E Zarychta, P Rhone, K Bielawski, M Michalska, D Ro??, B Ruszkowska
Adv Med Sci, 2019-02-26;64(2):216-223.
Species: Human
Sample Types: Plasma

Ginsenoside Rg1 Accelerates Paracrine Activity and Adipogenic Differentiation of Human Breast Adipose-Derived Stem Cells in a Dose-Dependent Manner In Vitro
Authors: ZJ Liang, X Lu, DD Zhu, XL Yi, FX Wu, N He, C Tang, CY Wei, HM Li
Cell Transplant, 2019-01-24;0(0):9636897198256.
Species: Human
Sample Types: Cell Culture Supernates

Impairment of hypoxia-induced angiogenesis by LDL involves a HIF-centered signaling network linking inflammatory TNF? and angiogenic VEGF
Authors: F Jin, X Zheng, Y Yang, G Yao, L Ye, TR Doeppner, DM Hermann, H Wang, Y Dai
Aging (Albany NY), 2019-01-18;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Selectively activated PRP exerts differential effects on tendon stem/progenitor cells and tendon healing
Authors: J Zhang, D Nie, K Williamson, JL Rocha, MV Hogan, JH Wang
J Tissue Eng, 2019-01-16;10(0):2.04173E+15.
Species: Human
Sample Types: Cell Culture Supernates

Epithelial Membrane Protein-2 (EMP2) Antibody Blockade Reduces Corneal Neovascularization in an In Vivo Model
Authors: MM Sun, AM Chan, SM Law, S Duarte, D Diaz-Aguil, M Wadehra, LK Gordon
Invest. Ophthalmol. Vis. Sci., 2019-01-02;60(1):245-254.
Species: Human
Sample Types: Cell Culture Supernates

A genetically engineered microRNA-34a prodrug demonstrates anti-tumor activity in a canine model of osteosarcoma
Authors: F Alegre, AR Ormonde, KM Snider, K Woolard, AM Yu, LA Wittenburg
PLoS ONE, 2018-12-31;13(12):e0209941.
Species: Canine
Sample Types: Cell Culture Supernates

Changes in brain white matter structure are associated with urine proteins in urologic chronic pelvic pain syndrome (UCPPS): A MAPP Network study
Authors: DC Woodworth, A Dagher, A Curatolo, M Sachdev, C Ashe-McNal, BD Naliboff, JS Labus, JR Landis, JJ Kutch, EA Mayer, RS Lee, MA Moses, BM Ellingson
PLoS ONE, 2018-12-05;13(12):e0206807.
Species: Human
Sample Types: Urine

Growth Differentiation Factor 11 treatment leads to neuronal and vascular improvements in the hippocampus of aged mice
Authors: C Ozek, RC Krolewski, SM Buchanan, LL Rubin
Sci Rep, 2018-11-23;8(1):17293.
Species: Human
Sample Types: Cell Culture Supernates

Comparison of the efficacy of cryopreserved human platelet lysate and refrigerated lyophilized human platelet lysate for wound healing
Authors: SC Notodihard, N Morimoto, N Kakudo, T Mitsui, TM Le, Y Tabata, K Kusumoto
Regen Ther, 2018-11-20;10(0):1-9.
Species: Human
Sample Types: Cell Lysates

Woodchuck VEGF (wVEGF) characteristics: Model for angiogenesis and human hepatocellular carcinoma directed therapies
Authors: H Huang, O Salavaggio, L Rivera, S Mukherjee, R Brekken, B Tennant, R Iyer, A Adjei
Arch. Biochem. Biophys., 2018-11-13;0(0):.
Species: Primate
Sample Types: Cell Lysates

Inhibition of oncogenic cap-dependent translation by 4EGI-1 reduces growth, enhances chemosensitivity and alters genome-wide translation in non-small cell lung cancer
Authors: A De, BA Jacobson, MS Peterson, ME Stelzner, J Jay-Dixon, MG Kratzke, MR Patel, PB Bitterman, RA Kratzke
Cancer Gene Ther., 2018-11-12;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Knockdown of CHCHD2 inhibits migration and angiogenesis of human renal cell carcinoma: A potential molecular marker for treatment of RCC
Authors: Q Cheng, D Qu, Z Lu, L Zhang
Oncol Lett, 2018-11-12;17(1):765-772.
Species: Human
Sample Types: Cell Culture Supernates

Quantitative proteomic analysis of aqueous humor from patients with drusen and reticular pseudodrusen in age-related macular degeneration
Authors: JH Baek, D Lim, KH Park, JB Chae, H Jang, J Lee, H Chung
BMC Ophthalmol, 2018-11-07;18(1):289.
Species: Human
Sample Types: Cell Culture Supernates

Evaluation of methodologies to determine the effect of specific active immunotherapy on VEGF levels in phase I clinical trial patients with advanced solid tumors
Authors: J Sánchez Ra, M Bequet-Rom, Y Morera Día, F Hernández-, A de la Torr, KH Selman-Hou, Y Martín Bau, CH Bermúdez B, M Limonta Fe, M Ayala Avil
Heliyon, 2018-11-02;4(11):e00906.
Species: Human
Sample Types: Serum

Properties of viable lyopreserved amnion are equivalent to viable cryopreserved amnion with the convenience of ambient storage
Authors: S Dhall, M Sathyamoor, JQ Kuang, T Hoffman, M Moorman, A Lerch, V Jacob, SM Sinclair, A Danilkovit
PLoS ONE, 2018-10-02;13(10):e0204060.
Species: Human
Sample Types: Tissue Homogenates

Diagnostic power of VEGF, MMP-9 and TIMP-1 in patients with breast cancer. A multivariate statistical analysis with ROC curve
Authors: M Zajkowska, E Gacuta, S Koz?owska, E Lubowicka, EK G?a?ewska, L Chrostek, M Szmitkowsk, P Paw?owski, M Zbucka-Kr?, S ?awicki
Adv Med Sci, 2018-09-15;64(1):1-8.
Species: Human
Sample Types: Plasma

The STAT3 inhibitor S3I-201 suppresses fibrogenesis and angiogenesis in liver fibrosis
Authors: Z Wang, J Li, W Xiao, J Long, H Zhang
Lab. Invest., 2018-09-11;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

VEGF165b, a splice variant of VEGF-A, promotes lung tumor progression and escape from anti-angiogenic therapies through a ?1 integrin/VEGFR autocrine loop
Authors: A Boudria, C Abou Fayca, T Jia, S Gout, M Keramidas, C Didier, N Lemaître, S Manet, JL Coll, AC Toffart, D Moro-Sibil, C Albiges-Ri, V Josserand, E Faurobert, C Brambilla, E Brambilla, S Gazzeri, B Eymin
Oncogene, 2018-09-07;0(0):.
Species: Human
Sample Types: Serum

1H-NMR and MALDI-TOF MS as metabolomic quality control tests to classify platelet derived medium additives for GMP compliant cell expansion procedures
Authors: F Agostini, M Ruzza, D Corpillo, L Biondi, E Acquadro, B Canepa, A Viale, M Battiston, F Serra, S Aime, M Mazzucato
PLoS ONE, 2018-09-06;13(9):e0203048.
Species: Human
Sample Types: Cell Culture Supernates

Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth
Authors: DH Bak, MJ Choi, SR Kim, BC Lee, JM Kim, ES Jeon, W Oh, ES Lim, BC Park, MJ Kim, J Na, BJ Kim
Korean J. Physiol. Pharmacol., 2018-08-27;22(5):555-566.
Species: Human
Sample Types: Cell Culture Supernates

The crucial role of blood VEGF kinetics in patients with locally advanced esophageal squamous cell carcinoma receiving curative concurrent chemoradiotherapy
Authors: YH Chen, HI Lu, CM Lo, YM Wang, SY Chou, CC Hsiao, CC Huang, LH Shih, SW Chen, SH Li
BMC Cancer, 2018-08-20;18(1):837.
Species: Human
Sample Types: Serum

Comments on Assays Used to Measure VEGF in the Presence of Anti-VEGF Therapeutics
Authors: E Wakshull, R Avery, M Maia
Invest. Ophthalmol. Vis. Sci., 2018-08-01;59(10):4106.
Species: Human
Sample Types: Serum

A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia
Authors: DE Foxler, KS Bridge, JG Foster, P Grevitt, S Curry, KM Shah, KM Davidson, A Nagano, E Gadaleta, HI Rhys, PT Kennedy, MA Hermida, TY Chang, PE Shaw, LE Reynolds, TR McKay, HW Wang, PS Ribeiro, MJ Plevin, D Lagos, NR Lemoine, P Rajan, TA Graham, C Chelala, KM Hodivala-D, I Spendlove, TV Sharp
EMBO Mol Med, 2018-08-01;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Host Immunological Effects of Partial Splenic Embolization in Patients with Liver Cirrhosis
Authors: Y Matsukiyo, H Nagai, T Matsui, Y Igarashi
J Immunol Res, 2018-07-15;2018(0):1746391.
Species: Human
Sample Types: Serum

StaPLs: versatile genetically encoded modules for engineering drug-inducible proteins
Authors: CL Jacobs, RK Badiee, MZ Lin
Nat. Methods, 2018-07-02;15(7):523-526.
Species: Human
Sample Types: Cell Culture Supernates

Long non-coding RNA UBE2CP3 enhances HCC cell secretion of VEGFA and promotes angiogenesis by activating ERK1/2/HIF-1?/VEGFA signalling in hepatocellular carcinoma
Authors: J Lin, S Cao, Y Wang, Y Hu, H Liu, J Li, J Chen, P Li, J Liu, Q Wang, L Zheng
J. Exp. Clin. Cancer Res., 2018-06-04;37(1):113.
Species: Human
Sample Types: Cell Culture Supernates

miR-10a rejuvenates aged human mesenchymal stem cells and improves heart function after myocardial infarction through KLF4
Authors: J Dong, Z Zhang, H Huang, P Mo, C Cheng, J Liu, W Huang, C Tian, C Zhang, J Li
Stem Cell Res Ther, 2018-05-30;9(1):151.
Species: Human
Sample Types: Cell Culture Supernates

Different patterns of inflammatory and angiogenic factors are associated with peritoneal small solute transport and peritoneal protein clearance in peritoneal dialysis patients
Authors: Y Shi, H Yan, J Yuan, H Zhang, J Huang, Z Ni, J Qian, W Fang
BMC Nephrol, 2018-05-23;19(1):119.
Species: Human
Sample Types: Serum

Matrix metalloproteinase-14 is a biomarker of angiogenic activity in proliferative diabetic retinopathy
Authors: AM Abu El-Asr, G Mohammad, E Allegaert, A Ahmad, MM Siddiquei, K Alam, PW Gikandi, G De Hertogh, G Opdenakker
Mol. Vis., 2018-05-18;24(0):394-406.
Species: Human
Sample Types: Vitreous Humor

Induction of chemokine (C-C motif) ligand 5 by Epstein-Barr virus infection enhances tumor angiogenesis in nasopharyngeal carcinoma
Authors: W Ma, L Feng, S Zhang, H Zhang, X Zhang, X Qi, Y Zhang, Q Feng, T Xiang, YX Zeng
Cancer Sci., 2018-04-28;109(5):1710-1722.
Species: Human
Sample Types: Cell Culture Supernates

Prognostic value of serum vascular endothelial growth factor and hematological responses in patients with newly-diagnosed POEMS syndrome
Authors: H Zhao, H Cai, C Wang, XF Huang, XX Cao, L Zhang, DB Zhou, J Li
Blood Cancer J, 2018-04-04;8(4):37.
Species: Human
Sample Types: Serum

Anti-inflammatory cytokine and angiogenic factors levels in vitreous samples of diabetic retinopathy patients
Authors: T Tsai, S Kuehn, N Tsiampalis, MK Vu, V Kakkassery, G Stute, HB Dick, SC Joachim
PLoS ONE, 2018-03-27;13(3):e0194603.
Species: Human
Sample Types: Vitreous Humor

Baseline serum vascular endothelial growth factor levels predict treatment response to antipsychotic medication in patients with schizophrenia
Authors: W Xiao, Q Zhan, F Ye, X Tang, J Li, H Dong, W Sha, X Zhang
Eur Neuropsychopharmacol, 2018-03-27;0(0):.
Species: Human
Sample Types: Serum

Association between the ratio of anti-angiogenic isoform of VEGF-A to total VEGF-A and adverse clinical outcomes in patients after acute myocardial infarction
Authors: K Harada, R Kikuchi, H Ishii, Y Shibata, S Suzuki, A Tanaka, A Suzuki, K Hirayama, T Murohara
Int J Cardiol Heart Vasc, 2018-03-22;19(0):3-7.
Species: Human
Sample Types: Serum

Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H2S Production
Authors: A Longchamp, T Mirabella, A Arduini, MR MacArthur, A Das, JH Treviño-Vi, C Hine, I Ben-Sahra, NH Knudsen, LE Brace, J Reynolds, P Mejia, M Tao, G Sharma, R Wang, JM Corpataux, JA Haefliger, KH Ahn, CH Lee, BD Manning, DA Sinclair, CS Chen, CK Ozaki, JR Mitchell
Cell, 2018-03-22;173(1):117-129.e14.
Species: Human
Sample Types: Cell Culture Supernates

Association of VEGFA variants with altered VEGF secretion and type 2 diabetes: A case-control study
Authors: N Sellami, LB Lamine, A Turki, S Sarray, M Jailani, AK Al-Ansari, M Ghorbel, T Mahjoub, WY Almawi
Cytokine, 2018-03-10;106(0):29-34.
Species: Human
Sample Types: Serum

Physical Exercise and Spatial Training: A Longitudinal Study of Effects on Cognition, Growth Factors, and Hippocampal Plasticity
Authors: L Woost, PL Bazin, M Taubert, R Trampel, CL Tardif, A Garthe, G Kempermann, U Renner, G Stalla, DVM Ott, V Rjosk, H Obrig, A Villringer, E Roggenhofe, TA Klein
Sci Rep, 2018-03-09;8(1):4239.
Species: Human
Sample Types: Serum

A safety and immunogenicity study of immunization with hVEGF26-104/RFASE in cynomolgus monkeys
Authors: MQ Wentink, HMW Verheul, AW Griffioen, KA Schafer, S McPherson, RJ Early, HJ van der Vl, TD de Gruijl
Vaccine, 2018-03-05;0(0):.
Species: Primate - Macaca fascicularis (Cynomolgus)
Sample Types: Serum

Comparing Alternative Ranibizumab Dosages for Safety and Efficacy in Retinopathy of Prematurity: A Randomized Clinical Trial
Authors: A Stahl, TU Krohne, N Eter, I Oberacher-, R Guthoff, S Meltendorf, O Ehrt, S Aisenbrey, J Roider, H Gerding, C Jandeck, LEH Smith, JM Walz
JAMA Pediatr, 2018-03-01;0(0):.
Species: Human
Sample Types: Plasma

Enhanced rapamycin delivery to hemangiomas by lipid polymer nanoparticles coupled with anti-VEGFR antibody
Authors: H Li, Y Teng, X Xu, J Liu
Int. J. Mol. Med., 2018-02-28;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Combinations of Bevacizumab and Erlotinib show activity in colorectal cancer independent of RAS status
Authors: P Mésange, A Bouygues, N Ferrand, M Sabbah, AE Escargueil, A Savina, B Chibaudel, C Tournigand, T Andre, A de Gramont, AK Larsen
Clin. Cancer Res., 2018-02-28;0(0):.
Species: Human
Sample Types: Whole Cells

VEGF and GLUT1 are highly heritable, inversely correlated and affected by dietary fat intake: Consequences for cognitive function in humans
Authors: R Schüler, N Seebeck, MA Osterhoff, V Witte, A Flöel, A Busjahn, A Jais, JC Brüning, T Frahnow, S Kabisch, O Pivovarova, S Hornemann, M Kruse, AFH Pfeiffer
Mol Metab, 2018-02-12;0(0):.
Species: Human
Sample Types: Serum

Hypoxia induces miR-153 through the IRE1?-XBP1 pathway to fine tune the HIF1?/VEGFA axis in breast cancer angiogenesis
Authors: H Liang, J Xiao, Z Zhou, J Wu, F Ge, Z Li, H Zhang, J Sun, F Li, R Liu, C Chen
Oncogene, 2018-01-25;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Intravitreal injection of aflibercept, an anti-VEGF antagonist, down-regulates plasma von Willebrand factor in patients with age-related macular degeneration
Authors: M Yamashita, M Matsumoto, M Hayakawa, K Sakai, Y Fujimura, N Ogata
Sci Rep, 2018-01-24;8(1):1491.
Species: Human
Sample Types: Plasma

A2E-associated cell death and inflammation in retinal pigmented epithelial cells from human induced pluripotent stem cells
Authors: VM Parmar, T Parmar, E Arai, L Perusek, A Maeda
Stem Cell Res, 2018-01-12;27(0):95-104.
Species: Human
Sample Types: Cell Culture Supernates

Effect of intensive multifactorial treatment on vascular progenitor cells in hypertensive patients
Authors: C Maroun-Eid, A Ortega-Her, J Modrego, M Abad-Cardi, JA García-Don, L Reinares, N Martell-Cl, D Gómez-Garr
PLoS ONE, 2018-01-05;13(1):e0190494.
Species: Human
Sample Types: Plasma

Elevated serum levels of cardiovascular biomarkers are associated with progression of renal cancer
Authors: T Kamai, Y Tokura, T Uematsu, K Sakamoto, I Suzuki, K Takei, T Narimatsu, T Kambara, H Yuki, H Betsunoh, H Abe, Y Fukabori, M Yashi, KI Yoshida
Open Heart, 2018-01-03;5(1):e000666.
Species: Human
Sample Types: Serum

Apolipoprotein M Inhibits Angiogenic and Inflammatory Response by Sphingosine 1-Phosphate on Retinal Pigment Epithelium Cells
Authors: R Terao, M Honjo, M Aihara
Int J Mol Sci, 2017-12-31;19(1):.
Species: Human
Sample Types: Cell Lysates

Cooperation between ZEB2 and Sp1 promotes cancer cell survival and angiogenesis during metastasis through induction of survivin and VEGF
Authors: D Ko, S Kim
Oncotarget, 2017-12-11;9(1):726-742.
Species: Human
Sample Types: Cell Culture Supernates

Significant inhibition of infantile hemangioma growth by sustained delivery of urea from liposomes-in-microspheres
Authors: X Zhu, X Guo, D Liu, Y Gong, J Sun, C Dong
Oncol. Rep., 2017-11-20;39(1):109-118.
Species: Human
Sample Types: Cell Culture Supernates

miRNA profiling of NurOwnï¿½: mesenchymal stem cells secreting neurotrophic factors
Authors: Y Gothelf, H Kaspi, N Abramov, R Aricha
Stem Cell Res Ther, 2017-11-07;8(1):249.
Species: Human
Sample Types: Cell Culture Supernates

Epigallocatechin gallate & curcumin prevent transforming growth factor beta 1-induced epithelial to mesenchymal transition in ARPE-19 cells
Authors: S Shanmugana, VN Sumantran, N Angayarkan
Indian J. Med. Res., 2017-11-01;146(0):S85-S96.
Species: Human
Sample Types: Cell Culture Supernates

Serum Vascular Endothelial Growth Factor (VEGF) as a Biomarker for Disease Activity in Lupus Nephritis
Authors: WSW Ghazali, R Iberahim, NSM Ashari
Malays J Med Sci, 2017-10-31;24(5):62-72.
Species: Human
Sample Types: Serum

Phenformin has anti-tumorigenic effects in human ovarian cancer cells and in an orthotopic mouse model of serous ovarian cancer
Authors: AL Jackson, W Sun, J Kilgore, H Guo, Z Fang, Y Yin, HM Jones, TP Gilliam, C Zhou, VL Bae-Jump
Oncotarget, 2017-10-24;8(59):100113-100127.
Species: Mouse
Sample Types: Serum

Comparative analyses of industrial-scale human platelet lysate preparations.
Authors: Jan Pierce, Eric Benedetti, Amber Preslar, Pam Jacobson, Ping Jin, David F Stroncek, Jo-Anna Reems
Transfusion, 2017-10-08;0(0):1537-2995.
Species: Human
Sample Types: Plasma

Corneal Mesenchymal Stromal Cells Are Directly Antiangiogenic via PEDF and sFLT-1
Authors: M Eslani, I Putra, X Shen, J Hamouie, N Afsharkham, S Besharat, MI Rosenblatt, R Dana, P Hematti, AR Djalilian
Invest. Ophthalmol. Vis. Sci., 2017-10-01;58(12):5507-5517.
Species: Human
Sample Types: Cell Culture Supernates

Inhibitory Effects of Total Triterpenoid Saponins Isolated from the Seeds of the Tea Plant (Camellia sinensis) on Human Ovarian Cancer Cells
Authors: LY Jia, XJ Wu, Y Gao, GO Rankin, A Pigliacamp, H Bucur, B Li, YY Tu, YC Chen
Molecules, 2017-09-30;22(10):.
Species: Human
Sample Types: Cell Culture Supernates

EGF regulation of proximal tubule cell proliferation and VEGF-A secretion
Authors: D Zepeda-Oro, HM Wen, BA Hamilton, NS Raikwar, CP Thomas
Physiol Rep, 2017-09-27;5(18):.
Species: Human
Sample Types: Cell Culture Supernates

Expression of the angiogenic mediator, angiopoietin-like 4, in the eyes of patients with proliferative sickle retinopathy
Authors: K Jee, M Rodrigues, F Kashiwabuc, BP Applewhite, I Han, G Lutty, MF Goldberg, GL Semenza, S Montaner, A Sodhi
PLoS ONE, 2017-08-23;12(8):e0183320.
Species: Human
Sample Types: Aqueous Humor

Gestational diabetes mellitus is associated with increased pro-migratory activation of vascular endothelial growth factor receptor 2 and reduced expression of vascular endothelial growth factor receptor 1
Authors: F Troncoso, J Acurio, K Herlitz, C Aguayo, P Bertoglia, E Guzman-Gut, M Loyola, M Gonzalez, M Rezgaoui, G Desoye, C Escudero
PLoS ONE, 2017-08-17;12(8):e0182509.
Species: Human
Sample Types: Cell Culture Supernates

Angiogenic T cell expansion correlates with severity of peripheral vascular damage in systemic sclerosis
Authors: M Manetti, S Pratesi, E Romano, S Bellando-R, I Rosa, S Guiducci, BS Fioretto, L Ibba-Manne, E Maggi, M Matucci-Ce
PLoS ONE, 2017-08-10;12(8):e0183102.
Species: Human
Sample Types: Serum

Secretome profiles of immortalized dental follicle cells using iTRAQ-based proteomic analysis
Authors: L Dou, Y Wu, Q Yan, J Wang, Y Zhang, P Ji
Sci Rep, 2017-08-04;7(1):7300.
Species: Human
Sample Types: Cell Culture Supernates

Tetrahydrocurcumin induces mesenchymal-epithelial transition and suppresses angiogenesis by targeting HIF-1? and autophagy in human osteosarcoma
Authors: Y Zhang, Y Liu, J Zou, L Yan, W Du, Y Zhang, H Sun, P Lu, S Geng, R Gu, H Zhang, Z Bi
Oncotarget, 2017-08-03;8(53):91134-91149.
Species: Human
Sample Types: Cell Culture Supernates

15-Lipoxygenase-1 re-expression in colorectal cancer alters endothelial cell features through enhanced expression of TSP-1 and ICAM-1
Authors: S Tunçer, AG Ke?kü?, M Çolako?lu, I Çimen, C Yener, Ö Konu, S Banerjee
Cell. Signal., 2017-07-28;39(0):44-54.
Species: Human
Sample Types: Cell Culture Supernates

Characteristics of the specific humoral response in patients with advanced solid tumors after active immunotherapy with a VEGF vaccine, at different antigen doses and using two distinct adjuvants
Authors: J Sánchez Ra, Y Morera Día, M Bequet-Rom, F Hernández-, KH Selman-Hou, A de la Torr, ER Santiesteb, Y Martín Bau, CH Bermúdez B, J de la Torr, JV Gavilondo, M Ayala Avil
BMC Immunol., 2017-07-26;18(1):39.
Species: Human
Sample Types: Serum

Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing
Authors: A Voissiere, E Jouberton, E Maubert, F Degoul, C Peyrode, JM Chezal, É Miot-Noira
PLoS ONE, 2017-07-13;12(7):e0181340.
Species: Human
Sample Types: Cell Culture Supernates

Improvement in asymmetric dimethylarginine and oxidative stress in patients with limb salvage after autologous mononuclear stem cell application for critical limb ischemia
Authors: J Madaric, M Valachovic, L Paulis, J Pribojova, R Mateova, K Sebekova, L Postulkova, T Madaricova, M Bucova, M Mistrik, I Vulev
Stem Cell Res Ther, 2017-07-12;8(1):165.
Species: Human
Sample Types: Cell Culture Supernates

Profiling of cytokines, chemokines and other soluble proteins as a potential biomarker in colorectal cancer and polyps
Authors: NA Johdi, L Mazlan, I Sagap, R Jamal
Cytokine, 2017-07-06;99(0):35-42.
Species: Human
Sample Types: Serum

Catecholamines facilitate VEGF-dependent angiogenesis via ?2-adrenoceptor-induced Epac1 and PKA activation
Authors: J Garg, YX Feng, SR Jansen, J Friedrich, F Lezoualc'h, M Schmidt, T Wieland
Oncotarget, 2017-07-04;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

MicroRNA Expression in Malignant Pleural Mesothelioma and Asbestosis: A Pilot Study
Authors: P Mozzoni, L Ampollini, M Goldoni, R Alinovi, M Tiseo, L Gnetti, P Carbognani, M Rusca, A Mutti, A Percesepe, M Corradi
Dis. Markers, 2017-07-03;2017(0):9645940.
Species: Human
Sample Types: Plasma

Effects of Secreted Mast Cell Mediators on Retinal Pigment Epithelial Cells: Focus on Mast Cell Tryptase
Authors: R Arai, A Usui-Ouchi, Y Ito, K Mashimo, A Murakami, N Ebihara
Mediators Inflamm., 2017-06-29;2017(0):3124753.
Species: Human
Sample Types: Cell Culture Supernates

Prognostic impact of blood and urinary angiogenic factor levels at diagnosis and during treatment in patients with osteosarcoma: a prospective study
Authors: MD Tabone, L Brugières, S Piperno-Ne, MA Selva, P Marec-Béra, H Pacquement, C Lervat, N Corradini, JC Gentet, R Couderc, A Chevance, C Mahier-Ait, N Entz-Werle, JY Blay, MC Le Deley
BMC Cancer, 2017-06-15;17(1):419.
Species: Human
Sample Types: Serum

Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1? and VEGF receptors
Authors: N Mahfouz, R Tahtouh, N Alaaeddine, J El Hajj, R Sarkis, R Hachem, I Raad, G Hilal
PLoS ONE, 2017-06-08;12(6):e0179202.
Species: Human
Sample Types: Cell Culture Supernates

Osteoprotegerin Is a New Regulator of Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy
Authors: AM Abu El-Asr, S Struyf, G Mohammad, M Gouwy, P Rytinx, MM Siddiquei, C Hernández, K Alam, A Mousa, G De Hertogh, G Opdenakker, R Simó
Invest. Ophthalmol. Vis. Sci., 2017-06-01;58(7):3189-3201.
Species: Human
Sample Types: Vitreous Humor

Monitoring response to anti-angiogenic mTOR inhibitor therapy in vivo using (111)In-bevacizumab
Authors: N Patel, S Able, D Allen, E Fokas, B Cornelisse, FV Gleeson, AL Harris, KA Vallis
EJNMMI Res, 2017-05-30;7(1):49.
Species: Xenograft
Sample Types: Tissue Homogenates

Clinical usefulness of videocapillaroscopy and selected endothelial cell activation markers in people with Type 1 diabetes mellitus complicated by microangiopathy
Authors: A Kuryliszyn, W Zarzycki, A Dubicki, D Moskal, B Koszty?a-H, A Hryniewicz
Adv Med Sci, 2017-05-23;62(2):368-373.
Species: Human
Sample Types: Serum

In smokers, Sonic hedgehog modulates pulmonary endothelial function through vascular endothelial growth factor
Authors: P Henno, S Grassin-De, E Belle, M Brollo, E Naline, E Sage, P Devillier, D Israël-Bie
Respir. Res., 2017-05-23;18(1):102.
Species: Human
Sample Types: Tissue Homogenates

Specific humoral and cellular immune responses in cancer patients undergoing chronic immunization with a VEGF-based therapeutic vaccine
Authors: Y Morera, J Sánchez, M Bequet-Rom, KH Selman-Hou, A de la Torr, F Hernández-, Y Martín, A Garabito, J Piñero, C Bermúdez, J de la Torr, M Ayala, JV Gavilondo
Vaccine, 2017-05-20;0(0):.
Species: Human
Sample Types: Serum

Pancreatic Cyst Fluid Vascular Endothelial Growth Factor A and Carcinoembryonic Antigen: A Highly Accurate Test for the Diagnosis of Serous Cystic Neoplasm
Authors: RA Carr, MT Yip-Schnei, S Dolejs, BA Hancock, H Wu, M Radovich, CM Schmidt
J. Am. Coll. Surg., 2017-05-18;0(0):.
Species: Human
Sample Types: Pancreatic Fluid

Circulating tumor cells and serum levels of MMP-2, MMP-9 and VEGF as markers of the metastatic process in patients with high risk of metastatic progression
Authors: M Skerenova, V Mikulova, O Capoun, T Zima, P Tesarova
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 2017-05-16;0(0):.
Species: Human
Sample Types: Serum

Extracellular matrix nitration alters growth factor release and activates bioactive complement in human retinal pigment epithelial cells
Authors: MA Fields, HE Bowrey, J Gong, EF Moreira, H Cai, LV Del Priore
PLoS ONE, 2017-05-15;12(5):e0177763.
Species: Human
Sample Types: Cell Culture Supernates

Ulcer healing effect of autologous mixed sheets consisting of fibroblasts and peripheral blood mononuclear cells in rabbit ischemic hind limb
Authors: Y Takeuchi, K Ueno, T Mizoguchi, M Samura, T Harada, A Oga, T Murata, T Hosoyama, N Morikage, K Hamano
Am J Transl Res, 2017-05-15;9(5):2340-2351.
Species: Human
Sample Types: Cell Culture Supernates

Synthetic Receptors Induce Anti Angiogenic and Stress Signaling on Human First Trimester Cytotrophoblast Cells
Authors: AF Pantho, M Price, AZ Ashraf, U Wajid, ME Khansari, A Jahan, SH Afroze, MM Rhaman, CR Johnson, TJ Kuehl, MA Hossain, MN Uddin
Int J Environ Res Public Health, 2017-05-11;14(5):.
Species: Human
Sample Types: Cell Culture Supernates

Polyethylene glycol-poly(?-benzyloxycarbonyl-l-lysine)-conjugated VEGF siRNA for antiangiogenic gene therapy in hepatocellular carcinoma
Authors: G Wang, X Gao, G Gu, Z Shao, M Li, P Wang, J Yang, X Cai, Y Li
Int J Nanomedicine, 2017-05-09;12(0):3591-3603.
Species: Human
Sample Types: Tissue Homogenates

The repressive effect of miR-148a on Wnt/?-catenin signaling involved in Glabridin-induced anti-angiogenesis in human breast cancer cells
Authors: J Mu, D Zhu, Z Shen, S Ning, Y Liu, J Chen, Y Li, Z Li
BMC Cancer, 2017-05-02;17(1):307.
Species: Human
Sample Types: Cell Culture Supernates

The production method affects the efficacy of platelet derivatives to expand mesenchymal stromal cells in vitro
Authors: M Bernardi, F Agostini, K Chieregato, E Amati, C Durante, M Rassu, M Ruggeri, S Sella, E Lombardi, M Mazzucato, G Astori
J Transl Med, 2017-05-01;15(1):90.
Species: Human
Sample Types: Cell Lysates

Evaluation of autologous skeletal muscle-derived factors for regenerative medicine applications
Authors: M Yoshikawa, T Nakasa, M Ishikawa, N Adachi, M Ochi
Bone Joint Res, 2017-05-01;6(5):277-283.
Species: Human
Sample Types: Tissue Homogenates

Neoalbaconol inhibits angiogenesis and tumor growth by suppressing EGFR-mediated VEGF production
Authors: Xinfang Yu
Mol. Carcinog, 2017-05-01;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

CXCL1 is critical for pre-metastatic niche formation and metastasis in colorectal cancer
Authors: D Wang, H Sun, J Wei, B Cen, RN DuBois
Cancer Res., 2017-04-28;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates

The Effects of Taekwondo Training on Peripheral Neuroplasticity-Related Growth Factors, Cerebral Blood Flow Velocity, and Cognitive Functions in Healthy Children: A Randomized Controlled Trial
Authors: SY Cho, WY So, HT Roh
Int J Environ Res Public Health, 2017-04-25;14(5):.
Species: Human
Sample Types: Serum

Biodegradable poly (lactic acid-co-glycolic acid) scaffolds as carriers for genetically-modified fibroblasts
Authors: T Perisic, Z Zhang, P Foehr, U Hopfner, K Klutz, RH Burgkart, A Slobodians, M Goeldner, HG Machens, AF Schilling
PLoS ONE, 2017-04-05;12(4):e0174860.
Species: Human
Sample Types: Cell Culture Supernates

C-X-C motif chemokine ligand 8 promotes endothelial cell homing via the Akt-signal transducer and activator of transcription pathway to accelerate healing of ischemic and hypoxic skin ulcers
Authors: L Shen, P Zhang, S Zhang, L Xie, L Yao, W Lang, J Lian, W Qin, M Zhang, L Ji
Exp Ther Med, 2017-04-05;13(6):3021-3031.
Species: Human
Sample Types: Cell Culture Supernates

Targeting NRAS(Q61K) mutant delays tumor growth and angiogenesis in non-small cell lung cancer
Authors: Z Song, F Liu, J Zhang
Am J Cancer Res, 2017-04-01;7(4):831-844.
Species: Human
Sample Types: Cell Culture Supernates

Vitamin D Decreases Serum VEGF Correlating with Clinical Improvement in Vitamin D-Deficient Women with PCOS: A Randomized Placebo-Controlled Trial
Authors: M Irani, DB Seifer, RV Grazi, S Irani, Z Rosenwaks, R Tal
Nutrients, 2017-03-28;9(4):.
Species: Human
Sample Types: Serum

Angiogenesis in newly regenerated bone by secretomes of human mesenchymal stem cells
Authors: W Katagiri, T Kawai, M Osugi, Y Sugimura-W, K Sakaguchi, T Kojima, T Kobayashi
Maxillofac Plast Reconstr Surg, 2017-03-25;39(1):8.
Species: Human
Sample Types: Cell Culture Supernates

High Plasma Lipid Levels Reduce Efficacy of Adenovirus-Mediated Gene Therapy
Authors: AM Kivelä, J Huusko, E Gurzeler, A Laine, MH Dijkstra, G Dragneva, CB Andersen, SK Moestrup, S Ylä-Herttu
Sci Rep, 2017-03-24;7(1):386.
Species: Human
Sample Types: Plasma

Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome
Authors: KC Clark, FA Fierro, EM Ko, NJ Walker, B Arzi, CG Tepper, H Dahlenburg, A Cicchetto, A Kol, L Marsh, WJ Murphy, N Fazel, DL Borjesson
Stem Cell Res Ther, 2017-03-20;8(1):69.
Species: Human
Sample Types: Cell Culture Supernates

Serum VEGF Levels in Helicobacter pylori Infection and Correlation with Helicobacter pylori cagA and vacA Genes
Authors: G Siregar, D Sari, T Sungkar
Open Access Maced J Med Sci, 2017-03-19;5(2):137-141.
Species: Human
Sample Types: Serum

IL-17 induces reactive astrocytes and up-regulation of vascular endothelial growth factor (VEGF) through JAK/STAT signaling
Authors: T You, Y Bi, J Li, M Zhang, X Chen, K Zhang, J Li
Sci Rep, 2017-03-10;7(0):41779.
Species: Human
Sample Types: Whole Cells

Efficacy of aflibercept (EYLEA(ï¿½)) on inhibition of human VEGF in vitro
Authors: M Schicht, K Hesse, H Schröder, E Naschberge, W Lamprecht, F Garreis, FP Paulsen, L Bräuer
Ann. Anat, 2017-03-07;0(0):.

Motor neurons control blood vessel patterning in the developing spinal cord
Authors: P Himmels, I Paredes, H Adler, A Karakatsan, R Luck, HH Marti, O Ermakova, E Rempel, ET Stoeckli, C Ruiz de Al
Nat Commun, 2017-03-06;8(0):14583.
Species: Mouse
Sample Types: Tissue Homogenates

Combination of the histone deacetylase inhibitor vorinostat with bevacizumab in patients with clear-cell renal cell carcinoma: a multicentre, single-arm phase I/II clinical trial
Authors: R Pili, G Liu, S Chintala, H Verheul, S Rehman, K Attwood, MA Lodge, R Wahl, JI Martin, KM Miles, S Paesante, R Adelaiye, A Godoy, S King, J Zwiebel, MA Carducci
Br. J. Cancer, 2017-02-21;0(0):.
Species: Human
Sample Types: Serum

Genome surgery using Cas9 ribonucleoproteins for the treatment of age-related macular degeneration
Authors: K Kim, SW Park, JH Kim, SH Lee, D Kim, T Koo, KE Kim, JH Kim, JS Kim
Genome Res, 2017-02-16;27(3):419-426.
Species: Human
Sample Types: Cell Culture Supernates

Hypoxic preconditioning of human cardiosphere-derived cell sheets enhances cellular functions via activation of the PI3K/Akt/mTOR/HIF-1? pathway
Authors: Y Tanaka, T Hosoyama, A Mikamo, H Kurazumi, A Nishimoto, K Ueno, B Shirasawa, K Hamano
Am J Transl Res, 2017-02-15;9(2):664-673.
Species: Human
Sample Types: Cell Culture Supernates

The Effect of Sunitinib Treatment in Human Melanoma Xenografts: Associations with Angiogenic Profiles
Authors: JV Gaustad, TG Simonsen, LM Andersen, EK Rofstad
Transl Oncol, 2017-02-03;10(2):158-167.
Species: Human
Sample Types: Cell Culture Supernates

Decreased REG1? expression suppresses growth, invasion and angiogenesis of bladder cancer
Authors: J Geng, J Fan, Q Wang, XP Zhang, L Kang, QY Li, YF Xu, B Peng, JH Zheng, XD Yao
Eur J Surg Oncol, 2017-02-02;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Effects of Histone Deacetylase Inhibitor (Valproic Acid) on the Expression of Hypoxia-inducible Factor-1 Alpha in Human Retinal Mï¿½ller Cells
Authors: YJ Kim, SJ Park, NR Kim, HS Chin
Korean J Ophthalmol, 2017-02-02;31(1):80-85.
Species: Human
Sample Types: Cell Lysates

Apolipoprotein E2 and E3, but Not E4, Promote Retinal Pathologic Neovascularization
Authors: T Masuda, M Shimazawa, Y Hashimoto, A Kojima, S Nakamura, S Suemori, K Mochizuki, H Kawakami, K Kawase, H Hara
Invest. Ophthalmol. Vis. Sci., 2017-02-01;58(2):1208-1217.
Species: Human
Sample Types: Vitreous Humor

Changes in Retinal Microcirculation After Intravitreal Ranibizumab Injection in Eyes With Macular Edema Secondary to Branch Retinal Vein Occlusion
Authors: M Fukami, T Iwase, K Yamamoto, H Kaneko, S Yasuda, H Terasaki
Invest. Ophthalmol. Vis. Sci, 2017-02-01;58(2):1246-1255.
Species: Human
Sample Types: Aqueous Humor

Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina
EMBO Mol Med, 2017-02-01;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Signal Factors Secreted by 2D and Spheroid Mesenchymal Stem Cells and by Cocultures of Mesenchymal Stem Cells Derived Microvesicles and Retinal Photoreceptor Neurons
Authors: L Xie, M Mao, L Zhou, L Zhang, B Jiang
Stem Cells Int, 2017-01-18;2017(0):2730472.
Species: Human
Sample Types: Cell Culture Supernates

Beneficial Effects of Reconstituted High-Density Lipoprotein (rHDL) on Circulating CD34+ Cells in Patients after an Acute Coronary Syndrome
Authors: C Gebhard, E Rh‚aume, C Berry, G Brand, AE Kernalegue, G Th‚berge-J, MA Alam, CY Lee, L Boileau, M Chabot-Bla, MC Guertin, MA Lavoie, J Gr‚goire, R Ibrahim, P L'Allier, JC Tardif
PLoS ONE, 2017-01-06;12(1):e0168448.
Species: Human
Sample Types: Serum

Antitumor therapeutic application of self-assembled RNAi-AuNP nanoconstructs: Combination of VEGF-RNAi and photothermal ablation
Theranostics, 2017-01-01;7(1):9-22.
Species: Human
Sample Types: Cell Culture Supernates

HTRA1 and TGF-?1 Concentrations in the Aqueous Humor of Patients With Neovascular Age-Related Macular Degeneration
Authors: GM Tosi, E Caldi, G Neri, E Nuti, D Marigliani, S Baiocchi, C Traversi, G Cevenini, A Tarantello, F Fusco, F Nardi, M Orlandini, F Galvagni
Invest. Ophthalmol. Vis. Sci, 2017-01-01;58(1):162-167.
Species: Human
Sample Types: Aqueous Humor

Inhibition of Hypoxia-Induced Retinal Angiogenesis by Specnuezhenide, an Effective Constituent of Ligustrum lucidum Ait., through Suppression of the HIF-1?/VEGF Signaling Pathway
Molecules, 2016-12-21;21(12):.
Species: Human
Sample Types: Cell Culture Supernates

Angiopoietin-2, Angiopoietin-1 and subclinical cardiovascular disease in Chronic Kidney Disease
Sci Rep, 2016-12-19;6(0):39400.
Species: Human
Sample Types: Serum

Impact of Hyperglycemia and Low Oxygen Tension on Adipose-Derived Stem Cells Compared with Dermal Fibroblasts and Keratinocytes: Importance for Wound Healing in Type 2 Diabetes
PLoS ONE, 2016-12-19;11(12):e0168058.
Species: Human
Sample Types: Cell Culture Supernates

The anti-angiogenic role of soluble-form VEGF receptor in malignant gliomas
Authors: Shingo Takano
Int. J. Oncol, 2016-12-19;0(0):.
Species: Human
Sample Types: Tissue Homogenates

Decreased levels of sRAGE in follicular fluid from patients with PCOS
Authors: BiJun Wang
Reproduction, 2016-12-13;0(0):.
Species: Human
Sample Types: Aspirated Follicle Fluid

No effect of yeast-like fungi on lipid metabolism and vascular endothelial growth factor level in children and adolescents with type 1 diabetes mellitus
Authors: Katarzyna Zorena
Ital J Pediatr, 2016-12-12;42(1):107.
Species: Human
Sample Types: Serum

ELK3 promotes the migration and invasion of liver cancer stem cells by targeting HIF-1?
Oncol. Rep, 2016-12-07;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Spectrum of Factors Triggering Endothelial Dysfunction in PIH
Authors: VS Jammalamad, P Abraham
J Clin Diagn Res, 2016-12-01;10(12):BC14-BC17.
Species: Human
Sample Types: Serum

Cell therapy in critical limb ischemia: A comprehensive analysis of two cell therapy products
Authors: Claire Tournois
Cytotherapy, 2016-11-30;0(0):.
Species: Human
Sample Types: Plasma

Desflurane inhalation before ischemia increases ischemia-reperfusion-induced vascular leakage in isolated rabbit lungs
Authors: Yoshiaki Oshima
Springerplus, 2016-11-29;5(1):2031.
Species: Human
Sample Types: BALF

Overcoming the bottleneck of platelet lysate supply in large-scale clinical expansion of adipose-derived stem cells: A comparison of fresh versus three types of platelet lysates from outdated buffy coat-derived platelet concentrates
Authors: Anne Fischer-Ni
Cytotherapy, 2016-11-22;0(0):.
Species: Human
Sample Types: Cell Cultue Supernates

Effect of OSA on hypoxic and inflammatory markers during CPAP withdrawal: Further evidence from three randomized control trials
Authors: Malcolm Kohler
Respirology, 2016-11-18;0(0):.
Species: Human
Sample Types: Plasma

VEGF released by deferoxamine preconditioned mesenchymal stem cells seeded on collagen-GAG substrates enhances neovascularization
Sci Rep, 2016-11-10;6(0):36879.
Species: Human
Sample Types: Cell Culture Supernates

(18)F-FLT PET/CT imaging in patients with advanced solid malignancies treated with axitinib on an intermittent dosing regimen
Authors: Glenn Liu
Cancer Chemother. Pharmacol., 2016-11-05;0(0):.
Species: Human
Sample Types: Plasma

Differential diagnosis of lung cancer, its metastasis and chronic obstructive pulmonary disease based on serum Vegf, Il-8 and MMP-9
Sci Rep, 2016-11-04;6(0):36065.
Species: Human
Sample Types: Serum

Comparison of change in end tidal carbon dioxide after three minutes of step exercise between systemic sclerosis patients with and without pulmonary hypertension
Authors: Elana J Bernstein
Rheumatology (Oxford), 2016-10-25;56(1):87-94.
Species: Human
Sample Types: Serum

Paracrine Mechanisms of Intravenous Bone Marrow-Derived Mononuclear Stem Cells in Chronic Ischemic Stroke
Authors: Rohit Bhatia
Cerebrovasc Dis Extra, 2016-10-19;6(3):107-119.
Species: Human
Sample Types: Serum

Vascular endothelial growth factor A is associated with the subsequent development of moderate or severe cardiac allograft vasculopathy in pediatric heart transplant recipients
Authors: David M Briscoe
J. Heart Lung Transplant., 2016-10-03;0(0):.
Species: Human
Sample Types: Plasma

Albuminuria Is Associated with Endothelial Dysfunction and Elevated Plasma Endothelin-1 in Sickle Cell Anemia
PLoS ONE, 2016-09-26;11(9):e0162652.
Species: Human
Sample Types: Plasma

Biological effects of plasma rich in growth factors (PRGF) on human endometrial fibroblasts
Authors: Gorka Orive
Eur. J. Obstet. Gynecol. Reprod. Biol., 2016-09-22;206(0):125-130.
Species: Human
Sample Types: Plasma

Unaltered Angiogenesis-Regulating Activities of Platelets in Mild Type 2 Diabetes Mellitus despite a Marked Platelet Hyperreactivity
PLoS ONE, 2016-09-09;11(9):e0162405.
Species: Human
Sample Types: Cell Culture Supernates

The Antiproliferative Effect of Bevacizumab on Human Tenon Fibroblasts Is Not Mediated by Vascular Endothelial Growth Factor Inhibition
Invest Ophthalmol Vis Sci, 2016-09-01;57(11):4970-4977.
Species: Human
Sample Types: Cell Culture Supernates

Innovative Flow Cytometry Allows Accurate Identification of Rare Circulating Cells Involved in Endothelial Dysfunction
PLoS ONE, 2016-08-25;11(8):e0160153.
Species: Human
Sample Types: Plasma

Growth factor and pro-inflammatory cytokine contents in platelet-rich plasma (PRP), plasma rich in growth factors (PRGF), advanced platelet-rich fibrin (A-PRF), and concentrated growth factors (CGF)
Authors: Hideo Masuki
Int J Implant Dent, 2016-08-22;2(1):19.
Species: Human
Sample Types: Platelet Rich Plasma (PRP)

Melanomas prevent endothelial cell death under restrictive culture conditions by signaling through AKT and p38 MAPK/ ERK-1/2 cascades
Authors: Asha M Das
Oncoimmunology, 2016-08-12;5(10):e1219826.
Species: Human
Sample Types: Cell Culture Supernates

Comparison of Anticancer Effects of Carbamazepine and Valproic Acid
Authors: L Akbarzadeh, T Moini Zanj, M Sabetkasae
Iran Red Crescent Med J, 2016-08-04;18(10):e37230.
Species: Human
Sample Types: Cell Culture Supernates

Serum Interleukin-18, Fetuin-A, Soluble Intercellular Adhesion Molecule-1, and Endothelin-1 in Ankylosing Spondylitis, Psoriatic Arthritis, and SAPHO Syndrome
Int J Mol Sci, 2016-08-03;17(8):.
Species: Human
Sample Types: Serum

Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling
Sci Rep, 2016-07-04;6(0):29029.
Species: Human
Sample Types: Cell Culture Supernates

LXY6090 - a novel manassantin A derivative - limits breast cancer growth through hypoxia-inducible factor-1 inhibition
Onco Targets Ther, 2016-06-24;9(0):3829-40.
Species: Human
Sample Types: Whole Cells

Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia
Authors: Ingrid C Weel
PLoS ONE, 2016-06-17;11(6):e0157584.
Species: Human
Sample Types: Tissue Homogenates

FGFR-Dependent and -Independent Paracrine Signaling by Sunitinib-Resistant RCC
Mol Cell Biol, 2016-06-15;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Prognostic study for overall survival in patients with newly diagnosed POEMS syndrome
Authors: C Wang
Leukemia, 2016-06-13;0(0):.
Species: Human
Sample Types: Serum

Activation of EGFR/p38/HIF-1? is pivotal for angiogenesis and tumorigenesis of malignantly transformed cells induced by hexavalent chromium
J Biol Chem, 2016-05-25;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Expression of Heat Shock Protein 27 in Melanoma Metastases Is Associated with Overall Response to Bevacizumab Monotherapy: Analyses of Predictive Markers in a Clinical Phase II Study
PLoS ONE, 2016-05-11;11(5):e0155242.
Species: Human
Sample Types: Plasma

Combined EGFR- and notch inhibition display additive inhibitory effect on glioblastoma cell viability and glioblastoma-induced endothelial cell sprouting in vitro.
Authors: Mikkel Staberg, Signe Regner Michaelse, Louise Stobbe Olsen, Mette Kjølhede Nedergaar, Mette Villingsh, Marie-Thérése Stockhaus, Petra Hamerlik, Hans Skovgaard Poulsen
Cancer Cell International, 2016-04-26;0(0):1475-2867.
Species: Human
Sample Types: Cell Culture Supernates

VEGF potentiates GD3-mediated immune suppression by human ovarian cancer cells
Authors: IV Tiper, SM Temkin, S Spiegel, SE Goldblum, RL Giuntoli, M Oelke, JP Schneck, TJ Webb
Clin Cancer Res, 2016-04-13;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Human lung fibroblasts may modulate dendritic cell phenotype and function: results from a pilot in vitro study
Authors: O Freynet, J Marchal-So, F Jean-Louis, A Mailleux, B Crestani, P Soler, L Michel
Respir Res, 2016-04-04;17(1):36.
Species: Human
Sample Types: Cell Culture Supernates

Lysyl Oxidase (LOX) transcriptionally regulates SNAI2 expression and TIMP4 secretion in human cancers
Authors: M Boufraqech, L Zhang, N Nilubol, SM Sadowski, S Kotian, MM Quezado, E Kebebew
Clin Cancer Res, 2016-03-30;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Effect of Glucose on Retinal Endothelial Cell Viability and VEGF Secretion
Authors: Keli Wright
HSOA J Cell Biol Cell Metabol, 2016-03-25;3(1):.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Cell Culture Supernates

A promising scaffold with excellent cytocompatibility and pro-angiogenesis action for dental tissue engineering: Strontium-doped calcium polyphosphate
Authors: H Qin, Z Yang, L Li, X Yang, J Liu, X Chen, X Yu
Dent Mater J, 2016-01-01;35(2):241-9.
Species: Human
Sample Types: Cell Culture Supernates

Intertumor heterogeneity in vascularity and invasiveness of artificial melanoma brain metastases.
Authors: Simonsen T, Gaustad J, Rofstad E
J Exp Clin Cancer Res, 2015-12-15;34(0):150.
Species: Human
Sample Types: Cell Culture Supernates

Identification of tumour-reactive lymphatic endothelial cells capable of inducing progression of gastric cancer.
Authors: Tokumoto M, Tanaka H, Tauchi Y, Kasashima H, Kurata K, Yashiro M, Sakurai K, Toyokawa T, Kubo N, Amano R, Kimura K, Muguruma K, Maeda K, Ohira M, Hirakawa K
Br J Cancer, 2015-09-10;113(7):1046-54.
Species: Human
Sample Types: Cell Culture Supernates

Rac1 Regulates Endometrial Secretory Function to Control Placental Development.
Authors: Davila J, Laws M, Kannan A, Li Q, Taylor R, Bagchi M, Bagchi I
PLoS Genet, 2015-08-25;11(8):e1005458.
Species: Human
Sample Types: Cell Culture Supernates

miR-126-3p Inhibits Thyroid Cancer Cell Growth and Metastasis, and Is Associated with Aggressive Thyroid Cancer.
Authors: Xiong Y, Kotian S, Zeiger M, Zhang L, Kebebew E
PLoS ONE, 2015-08-05;10(8):e0130496.
Species: Human
Sample Types: Cell Culture Supernates

Significant Correlation between Retinal Venous Tortuosity and Aqueous Vascular Endothelial Growth Factor Concentration in Eyes with Central Retinal Vein Occlusion.
Authors: Yasuda S, Kachi S, Kondo M, Ueno S, Kaneko H, Terasaki H
PLoS ONE, 2015-07-27;10(7):e0134267.
Species: Human
Sample Types: Aqueous Humor

STAT3 Protein Regulates Vascular Smooth Muscle Cell Phenotypic Switch by Interaction with Myocardin.
Authors: Liao X, Wang N, Zhao D, Zheng D, Zheng L, Xing W, Ma W, Bao L, Dong J, Zhang T
J Biol Chem, 2015-06-22;290(32):19641-52.
Species: Human
Sample Types: Cell Culture Supernates

MEK Inhibitor PD-0325901 Overcomes Resistance to PI3K/mTOR Inhibitor PF-5212384 and Potentiates Antitumor Effects in Human Head and Neck Squamous Cell Carcinoma.
Authors: Mohan S, Vander Broek R, Shah S, Eytan D, Pierce M, Carlson S, Coupar J, Zhang J, Cheng H, Chen Z, Van Waes C
Clin Cancer Res, 2015-05-14;21(17):3946-56.
Species: Human
Sample Types: Cell Culture Supernates

Selective Interference Targeting of Lnk in Umbilical Cord-Derived Late Endothelial Progenitor Cells Improves Vascular Repair, Following Hind Limb Ischemic Injury, via Regulation of JAK2/STAT3 Signaling.
Authors: Lee, Sang Hun, Lee, Kyeung B, Lee, Jun Hee, Kang, Songhwa, Kim, Hwi Gon, Asahara, Takayuki, Kwon, Sang Mo
Stem Cells, 2015-05-01;33(5):1490-500.
Species: Human
Sample Types: Cell Culture Supernates

High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFkappaB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts.
Authors: Rudisch A, Dewhurst M, Horga L, Kramer N, Harrer N, Dong M, van der Kuip H, Wernitznig A, Bernthaler A, Dolznig H, Sommergruber W
PLoS ONE, 2015-04-28;10(4):e0124283.
Species: Human
Sample Types: Cell Culture Supernates

Production of IL-8, VEGF and Elastase by Circulating and Intraplaque Neutrophils in Patients with Carotid Atherosclerosis.
Authors: Marino F, Tozzi M, Schembri L, Ferraro S, Tarallo A, Scanzano A, Legnaro M, Castelli P, Cosentino M
PLoS ONE, 2015-04-20;10(4):e0124565.
Species: Human
Sample Types: Cell Culture Supernates

Deleted in malignant brain tumors 1 (DMBT1) elicits increased VEGF and decreased IL-6 production in type II lung epithelial cells.
Authors: Muller H, Nagel C, Weiss C, Mollenhauer J, Poeschl J
BMC Pulm Med, 2015-04-08;15(0):32.
Species: Human
Sample Types: Tissue Secretion

VEGF in patients with advanced hepatocellular carcinoma receiving intra-arterial chemotherapy.
Authors: Matsui D, Nagai H, Mukozu T, Ogino Y, Sumino Y
Anticancer Res, 2015-04-01;35(4):2205-10.
Species: Human
Sample Types: Serum

Obstructive sleep apnoea syndrome, endothelial function and markers of endothelialization. Changes after CPAP.
Authors: Munoz-Hernandez R, Vallejo-Vaz A, Sanchez Armengol A, Moreno-Luna R, Caballero-Eraso C, Macher H, Villar J, Merino A, Castell J, Capote F, Stiefel P
PLoS ONE, 2015-03-27;10(3):e0122091.
Species: Human
Sample Types: Serum

The tyrosine phosphatase SHP-1 regulates hypoxia inducible factor-1alpha (HIF-1alpha) protein levels in endothelial cells under hypoxia.
Authors: Alig S, Stampnik Y, Pircher J, Rotter R, Gaitzsch E, Ribeiro A, Wornle M, Krotz F, Mannell H
PLoS ONE, 2015-03-23;10(3):e0121113.
Species: Human
Sample Types: Cell Culture Supernates

Ruthenium polypyridyl complex inhibits growth and metastasis of breast cancer cells by suppressing FAK signaling with enhancement of TRAIL-induced apoptosis.
Authors: Cao, Wenqiang, Zheng, Wenjie, Chen, Tianfeng
Sci Rep, 2015-03-17;5(0):9157.
Species: Human
Sample Types: Cell Culture Supernates

A randomized phase II study of capecitabine-based chemoradiation with or without bevacizumab in resectable locally advanced rectal cancer: clinical and biological features.
Authors: Salazar R, Capdevila J, Laquente B, Manzano J, Pericay C, Villacampa M, Lopez C, Losa F, Safont M, Gomez A, Alonso V, Escudero P, Gallego J, Sastre J, Gravalos C, Biondo S, Palacios A, Aranda E
BMC Cancer, 2015-02-26;15(0):60.
Species: Human
Sample Types: Plasma

Tanshinone IIA inhibits HIF-1alpha and VEGF expression in breast cancer cells via mTOR/p70S6K/RPS6/4E-BP1 signaling pathway.
Authors: Li G, Shan C, Liu L, Zhou T, Zhou J, Hu X, Chen Y, Cui H, Gao N
PLoS ONE, 2015-02-06;10(2):e0117440.
Species: Human
Sample Types: Cell Culture Supernates

In situ normoxia enhances survival and proliferation rate of human adipose tissue-derived stromal cells without increasing the risk of tumourigenesis.
Authors: Choi, Jane Ru, Pingguan-Murphy, Belinda, Wan Abas, Wan Abu, Yong, Kar Wey, Poon, Chi Tat, Noor Azmi, Mat Aden, Omar, Siti Zaw, Chua, Kien Hui, Xu, Feng, Wan Safwani, Wan Kama
PLoS ONE, 2015-01-23;10(1):e0115034.
Species: Human
Sample Types: Cell Culture Supernates

The anti-angiogenic and cytotoxic effects of the boswellic acid analog BA145 are potentiated by autophagy inhibitors.
Authors: Pathania A, Wani Z, Guru S, Kumar S, Bhushan S, Korkaya H, Seals D, Kumar A, Mondhe D, Ahmed Z, Chandan B, Malik F
Mol Cancer, 2015-01-21;14(1):6.
Species: Human
Sample Types: Cell Culture Supernates

Gain of HIF-1alpha under normoxia in cancer mediates immune adaptation through the AKT/ERK and VEGFA axes.
Authors: Lee Y, Bae H, Noh K, Song K, Ye S, Mao C, Lee K, Wu T, Kim T
Clin Cancer Res, 2015-01-14;21(6):1438-46.
Species: Human
Sample Types: Cell Culture Supernates

Prognostic significance of pretreatment VEGF, survivin, and Smac/DIABLO serum levels in patients with serous ovarian carcinoma.
Authors: Dobrzycka B, Mackowiak-Matejczyk B, Terlikowska K, Kulesza-Bronczyk B, Kinalski M, Terlikowski S
Tumour Biol, 2015-01-12;0(0):4157.
Species: Human
Sample Types: Serum

Inhibition of placental growth factor in renal cell carcinoma.
Authors: Bessho H, Wong B, Huang D, Siew E, Huang D, Tan J, Ong C, Tan S, Matsumoto K, Iwamura M, Teh B
Anticancer Res, 2015-01-01;35(1):531-41.
Species: Human
Sample Types: Cell Culture Supernates

Gene electro transfer of plasmid encoding vascular endothelial growth factor for enhanced expression and perfusion in the ischemic swine heart.
Authors: Hargrave, Barbara, Strange, Robert J, Navare, Sagar, Stratton, Michael, Burcus, Nina, Murray, Len, Lundberg, Cathryn, Bulysheva, Anna, Li, Fanying, Heller, Richard
PLoS ONE, 2014-12-29;9(12):e115235.
Species: Human
Sample Types: Tissue Homogenates

Selecting bioactive phenolic compounds as potential agents to inhibit proliferation and VEGF expression in human ovarian cancer cells.
Authors: He Z, Li B, Rankin G, Rojanasakul Y, Chen Y
Oncol Lett, 2014-12-22;9(3):1444-1450.
Species: Human
Sample Types: Cell Culture Supernates

Effects of a single intravitreal injection of aflibercept and ranibizumab on glomeruli of monkeys.
Authors: Tschulakow A, Christner S, Julien S, Ludinsky M, van der Giet M, Schraermeyer U
PLoS ONE, 2014-11-21;9(11):e113701.
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Plasma

O-GlcNAc modification of transcription factor Sp1 mediates hyperglycemia-induced VEGF-A upregulation in retinal cells.
Authors: Donovan K, Alekseev O, Qi X, Cho W, Azizkhan-Clifford J
Invest Ophthalmol Vis Sci, 2014-10-28;55(12):7862-73.
Species: Human
Sample Types: Cell Culture Supernates

Anti-angiogenic pathway associations of the 3p21.3 mapped BLU gene in nasopharyngeal carcinoma.
Authors: Cheng Y, Ho R, Chan K, Kan R, Tung E, Lung H, Yau W, Cheung A, Ko J, Zhang Z, Luo D, Feng Z, Chen S, Guan X, Kwong D, Stanbridge E, Lung M
Oncogene, 2014-10-27;34(32):4219-28.
Species: Human
Sample Types: Cell Culture Supernates

Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer.
Authors: Sallinen H, Heikura T, Koponen J, Kosma V, Heinonen S, Yla-Herttuala S, Anttila M
BMC Cancer, 2014-09-23;14(0):696.
Species: Human
Sample Types: Serum

Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced beta-catenin/Tcf-Lef dependent transcription.
Authors: Fernandez J, Rodriguez D, Valenzuela M, Calderon C, Urzua U, Munroe D, Rosas C, Lemus D, Diaz N, Wright M, Leyton L, Tapia J, Quest A
Mol Cancer, 2014-09-09;13(0):209.
Species: Human
Sample Types: Cell Culture Supernates

Engineering the human thymic microenvironment to support thymopoiesis in vivo.
Authors: Chung B, Montel-Hagen A, Ge S, Blumberg G, Kim K, Klein S, Zhu Y, Parekh C, Balamurugan A, Yang O, Crooks G
Stem Cells, 2014-09-01;32(9):2386-96.
Species: Human
Sample Types: Whole Cells

Interferon-beta inhibits glioma angiogenesis through downregulation of vascular endothelial growth factor and upregulation of interferon inducible protein 10.
Authors: Takano S, Ishikawa E, Matsuda M, Yamamoto T, Matsumura A
Int J Oncol, 2014-08-25;45(5):1837-46.
Species: Human
Sample Types: Cell Culture Supernates

Evaluation of a new recombinant oncolytic vaccinia virus strain GLV-5b451 for feline mammary carcinoma therapy.
Authors: Adelfinger M, Gentschev I, Grimm de Guibert J, Weibel S, Langbein-Laugwitz J, Hartl B, Murua Escobar H, Nolte I, Chen N, Aguilar R, Yu Y, Zhang Q, Frentzen A, Szalay A
PLoS ONE, 2014-08-05;9(8):e104337.
Species: Feline
Sample Types: Cell Culture Supernates

Effects of pitavastatin versus atorvastatin on the peripheral endothelial progenitor cells and vascular endothelial growth factor in high-risk patients: a pilot prospective, double-blind, randomized study.
Authors: Lin L, Huang C, Chen J, Wu T, Leu H, Huang P, Chang T, Lin S, Chen J
Cardiovasc Diabetol, 2014-07-16;13(0):111.
Species: Human
Sample Types: Serum

Interleukin 4, interleukin 6 and osteopontin-serological markers of head and neck malignancy in primary diagnostics: A pilot study.
Authors: Aderhold C, Grobschmidt G, Sauter A, Faber A, Hormann K, Schultz J
Oncol Lett, 2014-07-04;8(3):1112-1118.
Species: Human
Sample Types: Serum

Establishment of a novel clear cell sarcoma cell line (Hewga-CCS), and investigation of the antitumor effects of pazopanib on Hewga-CCS.
Authors: Outani, Hidetats, Tanaka, Takaaki, Wakamatsu, Toru, Imura, Yoshinor, Hamada, Kenichir, Araki, Nobuhito, Itoh, Kazuyuki, Yoshikawa, Hideki, Naka, Norifumi
BMC Cancer, 2014-06-19;14(0):455.
Species: Human
Sample Types: Cell Culture Supernates

Ex vivo expansion of bovine corneal endothelial cells in xeno-free medium supplemented with platelet releasate.
Authors: Chou M, Burnouf T, Wang T
PLoS ONE, 2014-06-19;9(6):e99145.
Species: Human
Sample Types: Cell Culture Supernates

Metabolic impact of anti-angiogenic agents on U87 glioma cells.
Authors: Mesti T, Savarin P, Triba M, Le Moyec L, Ocvirk J, Banissi C, Carpentier A
PLoS ONE, 2014-06-12;9(6):e99198.
Species: Human
Sample Types: Cell Culture Supernates

SHARP1 suppresses angiogenesis of endometrial cancer by decreasing hypoxia-inducible factor-1alpha level.
Authors: Liao Y, Lu W, Che Q, Yang T, Qiu H, Zhang H, He X, Wang J, Qiu M, Zou Y, Gu W, Wan X
PLoS ONE, 2014-06-11;9(6):e99907.
Species: Human
Sample Types: Cell Culture Supernates

Molecular patterns in deficient mismatch repair colorectal tumours: results from a French prospective multicentric biological and genetic study.
Authors: Etienne-Grimaldi M, Mahamat A, Chazal M, Laurent-Puig P, Olschwang S, Gaub M, Formento J, Formento P, Sudaka A, Boige V, Abderrahim-Ferkoune A, Benchimol D, Andre T, Houry S, Faucheron J, Letoublon C, Gilly F, Delpero J, Lasser P, Pradere B, Pezet D, Penault-Llorca F, Milano G
Br J Cancer, 2014-05-06;110(11):2728-37.
Species: Human
Sample Types: Tissue Homogenates

Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye.
Authors: Michael, Iacovos, Westenskow, Peter D, Hacibekiroglu, Sabiha, Greenwald, Alissa C, Ballios, Brian G, Kurihara, Toshihid, Li, Zhijie, Warren, Carmen M, Zhang, Puzheng, Aguilar, Edith, Donaldson, Laura, Marchetti, Valentin, Baba, Takeshi, Hussein, Samer M, Sung, Hoon-Ki, Iruela-Arispe, M Luisa, Rini, James M, van der Kooy, Derek, Friedlander, Martin, Nagy, Andras
EMBO Mol Med, 2014-05-01;6(5):604-23.
Species: Human
Sample Types: Cell Culture Supernates

Net platelet angiogenic activity (NPAA) correlates with progression and prognosis of non-small cell lung cancer.
Authors: Yao L, Dong H, Luo Y, Du J, Hu W
PLoS ONE, 2014-04-30;9(4):e96206.
Species: Human
Sample Types: Cell Lysates

Peroxisome proliferator-activated receptor gamma ligands inhibit VEGF-mediated vasculogenic mimicry of prostate cancer through the AKT signaling pathway.
Authors: Qin L, Ren Y, Chen A, Guo F, Xu F, Gong C, Cheng P, Du Y, Liao H
Mol Med Rep, 2014-04-29;10(1):276-82.
Species: Human
Sample Types: Cell Culture Supernates

Epidithiodiketopiperazines (ETPs) exhibit in vitro antiangiogenic and in vivo antitumor activity by disrupting the HIF-1alpha/p300 complex in a preclinical model of prostate cancer.
Authors: Reece K, Richardson E, Cook K, Campbell T, Pisle S, Holly A, Venzon D, Liewehr D, Chau C, Price D, Figg W
Mol Cancer, 2014-04-28;13(0):91.
Species: Human
Sample Types: Cell Culture Supernates

WNT5A induces release of exosomes containing pro-angiogenic and immunosuppressive factors from malignant melanoma cells.
Authors: Ekstrom E, Bergenfelz C, von Bulow V, Serifler F, Carlemalm E, Jonsson G, Andersson T, Leandersson K
Mol Cancer, 2014-04-26;13(0):88.
Species: Human
Sample Types: Cell Culture Supernates

Reduction of maternal circulating endothelial progenitor cells in human pregnancies with intrauterine growth restriction.
Authors: Calcaterra F, Taddeo A, Colombo E, Cappelletti M, Martinelli A, Calabrese S, Mavilio D, Cetin I, Della Bella S
Placenta, 2014-04-26;35(7):431-6.
Species: Human
Sample Types: Plasma

Effects of high intensity training and high volume training on endothelial microparticles and angiogenic growth factors.
Authors: Wahl P, Jansen F, Achtzehn S, Schmitz T, Bloch W, Mester J, Werner N
PLoS ONE, 2014-04-25;9(4):e96024.
Species: Human
Sample Types: Serum

Oestrogen-induced angiogenesis promotes adenomyosis by activating the Slug-VEGF axis in endometrial epithelial cells.
Authors: Huang T, Chen Y, Chou T, Chen C, Li H, Huang B, Tsai H, Lan H, Chang C, Twu N, Yen M, Wang P, Chao K, Lee C, Yang M
J Cell Mol Med, 2014-04-24;18(7):1358-71.
Species: Human
Sample Types: Cell Culture Supernates

A method to assess target gene involvement in angiogenesis in vitro and in vivo using lentiviral vectors expressing shRNA.
Authors: Blosser, Wayne, Vakana, Eliza, Wyss, Lisa V, Swearingen, Michelle, Stewart, Julie, Stancato, Louis, Tate, Courtney
PLoS ONE, 2014-04-23;9(4):e96036.
Species: Human
Sample Types: Cell Culture Supernates

Sunitinib suppress neuroblastoma growth through degradation of MYCN and inhibition of angiogenesis.
Authors: Calero R, Morchon E, Johnsen J, Serrano R
PLoS ONE, 2014-04-23;9(4):e95628.
Species: Human
Sample Types: Cell Culture Supernates

Rapamycin inhibits Toll-like receptor 4-induced pro-oncogenic function in head and neck squamous cell carcinoma.
Authors: Ren G, Hu J, Wang R, Han W, Zhao M, Zhou G, Zhang C, Zhang Z
Oncol Rep, 2014-04-11;31(6):2804-10.
Species: Human
Sample Types: Whole Cells

Surgical sutures filled with adipose-derived stem cells promote wound healing.
Authors: Reckhenrich A, Kirsch B, Wahl E, Schenck T, Rezaeian F, Harder Y, Foehr P, Machens H, Egana J
PLoS ONE, 2014-03-13;9(3):e91169.
Species: Human
Sample Types: Cell Culture Supernates

Hepatitis C virus core protein induces hypoxia-inducible factor 1alpha-mediated vascular endothelial growth factor expression in Huh7.5.1 cells.
Authors: Zhu C, Liu X, Wang S, Yan X, Tang Z, Wu K, Li Y, Liu F
Mol Med Rep, 2014-03-11;9(5):2010-4.
Species: Human
Sample Types: Cell Culture Supernates

alpha6-Integrin is required for the adhesion and vasculogenic potential of hemangioma stem cells.
Authors: Smadja D, Guerin C, Boscolo E, Bieche I, Mulliken J, Bischoff J
Stem Cells, 2014-03-01;32(3):684-93.
Species: Human
Sample Types: Cell Culture Supernates

Temsirolimus inhibits proliferation and migration in retinal pigment epithelial and endothelial cells via mTOR inhibition and decreases VEGF and PDGF expression.
Authors: Liegl, Raffael, Koenig, Susanna, Siedlecki, Jakob, Haritoglou, Christos, Kampik, Anselm, Kernt, Marcus
PLoS ONE, 2014-02-26;9(2):e88203.
Species: Human
Sample Types: Cell Culture Supernates

COX-2 silencing enhances tamoxifen antitumor activity in breast cancer in vivo and in vitro.
Authors: Du Y, Shi A, Han B, Li S, Wu D, Jia H, Zheng C, Ren L, Fan Z
Int J Oncol, 2014-02-12;44(4):1385-93.
Species: Human
Sample Types: Cell Culture Supernates

Pathogen-free, plasma-poor platelet lysate and expansion of human mesenchymal stem cells.
Authors: Iudicone, Paola, Fioravanti, Daniela, Bonanno, Giuseppi, Miceli, Michelin, Lavorino, Claudio, Totta, Pierange, Frati, Luigi, Nuti, Marianna, Pierelli, Luca
J Transl Med, 2014-01-27;12(0):28.
Species: Human
Sample Types: Cell Culture Supernates

Role of RUNX3 in suppressing metastasis and angiogenesis of human prostate cancer.
Authors: Chen, Feifei, Wang, Meng, Bai, Jin, Liu, Qinghua, Xi, Yaguang, Li, Wang, Zheng, Junnian
PLoS ONE, 2014-01-24;9(1):e86917.
Species: Human
Sample Types: Cell Culture Supernates

Systemic upregulation of PDGF-B in patients with neovascular AMD.
Authors: Zehetner C, Kirchmair R, Neururer S, Kralinger M, Bechrakis N, Kieselbach G
Invest Ophthalmol Vis Sci, 2014-01-20;55(1):337-44.
Species: Human
Sample Types: Plasma

A synthetic dl-nordihydroguaiaretic acid (Nordy), inhibits angiogenesis, invasion and proliferation of glioma stem cells within a zebrafish xenotransplantation model.
Authors: Yang X, Cui W, Yu S, Xu C, Chen G, Gu A, Li T, Cui Y, Zhang X, Bian X
PLoS ONE, 2014-01-15;9(1):e85759.
Species: Human
Sample Types: Cell Culture Supernates

Cbx4 governs HIF-1alpha to potentiate angiogenesis of hepatocellular carcinoma by its SUMO E3 ligase activity.
Authors: Li J, Xu Y, Long X, Wang W, Jiao H, Mei Z, Yin Q, Ma L, Zhou A, Wang L, Yao M, Xia Q, Chen G
Cancer Cell, 2014-01-13;25(1):118-31.
Species: Human
Sample Types: Cell Culture Supernates

Role of serum VEGFA, TIMP2, MMP2 and MMP9 in monitoring response to adjuvant radiochemotherapy in patients with primary cervical cancer--results of a companion protocol of the randomized NOGGO-AGO phase III clinical trial.
Authors: Braicu E, Gasimli K, Richter R, Nassir M, Kummel S, Blohmer J, Yalcinkaya I, Chekerov R, Ignat I, Ionescu A, Mentze M, Fotopoulou C, Pop C, Lichtenegger W, Sehouli J
Anticancer Res, 2014-01-01;34(1):385-91.
Species: Human
Sample Types: Serum

Relationship between vitreous levels of matrix metalloproteinases and vascular endothelial growth factor in proliferative diabetic retinopathy.
Authors: Abu El-Asrar, Ahmed M, Mohammad, Ghulam, Nawaz, Mohd Imt, Siddiquei, Mohammad, Van den Eynde, Kathleen, Mousa, Ahmed, De Hertogh, Gert, Opdenakker, Ghislain
PLoS ONE, 2013-12-31;8(12):e85857.
Species: Human
Sample Types: Vitreous Humor

Inhibition of STAT3 reduces astrocytoma cell invasion and constitutive activation of STAT3 predicts poor prognosis in human astrocytoma.
Authors: Liang, Qinchuan, Ma, Chenkai, Zhao, Yang, Gao, Guodong, Ma, Jie
PLoS ONE, 2013-12-30;8(12):e84723.
Species: Human
Sample Types: Cell Culture Supernates

Effect of platelet lysate on human cells involved in different phases of wound healing.
Authors: Barsotti M, Losi P, Briganti E, Sanguinetti E, Magera A, Al Kayal T, Feriani R, Di Stefano R, Soldani G
PLoS ONE, 2013-12-27;8(12):e84753.
Species: Human
Sample Types: Cell Lysates

Designing nanotopographical density of extracellular matrix for controlled morphology and function of human mesenchymal stem cells.
Authors: Kim J, Kim H, Lim K, Kim Y, Seonwoo H, Park S, Lim H, Kim D, Suh K, Choung P, Choung Y, Chung J
Sci Rep, 2013-12-19;3(0):3552.
Species: Human
Sample Types: Cell Culture Supernates

Endoplasmic reticulum (ER) stress and hypoxia response pathways interact to potentiate hypoxia-inducible factor 1 (HIF-1) transcriptional activity on targets like vascular endothelial growth factor (VEGF).
Authors: Pereira, Ethel R, Frudd, Karen, Awad, Walid, Hendershot, Linda M
J Biol Chem, 2013-12-17;289(6):3352-64.
Species: Human
Sample Types: Cell Culture Supernates

Caspase 3 involves in neuroplasticity, microglial activation and neurogenesis in the mice hippocampus after intracerebral injection of kainic acid.
Authors: Tzeng, Tsai-Ten, Tsay, Huey-Jen, Chang, Luping, Hsu, Chia-Lin, Lai, Tzu-Hsua, Huang, Fong-Lee, Shiao, Young-Ji
J Biomed Sci, 2013-12-06;20(0):90.
Species: Human
Sample Types: Cell Culture Supernates

Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination.
Authors: Zhan Z, Xie X, Cao H, Zhou X, Zhang X, Fan H, Liu Z
Autophagy, 2013-12-04;10(2):257-68.
Species: Human
Sample Types: Cell Culture Supernates

A metabolic shift favoring sphingosine 1-phosphate at the expense of ceramide controls glioblastoma angiogenesis.
Authors: Abuhusain, Hazem J, Matin, Azadeh, Qiao, Qiao, Shen, Han, Kain, Nupur, Day, Bryan W, Stringer, Brett W, Daniels, Benjamin, Laaksonen, Maarit A, Teo, Charlie, McDonald, Kerrie L, Don, Anthony
J Biol Chem, 2013-11-21;288(52):37355-64.
Species: Human
Sample Types: Cell Culture Supernates

Long-term survival and biomarker correlates of tasquinimod efficacy in a multicenter randomized study of men with minimally symptomatic metastatic castration-resistant prostate cancer.
Authors: Armstrong A, Haggman M, Stadler W, Gingrich J, Assikis V, Polikoff J, Damber J, Belkoff L, Nordle O, Forsberg G, Carducci M, Pili R
Clin Cancer Res, 2013-11-19;19(24):6891-901.
Species: Human
Sample Types: Plasma

The contributions of HIF-target genes to tumor growth in RCC.
Authors: Zhang, Ting, Niu, Xiaohua, Liao, Lili, Cho, Eun-Ah, Yang, Haifeng
PLoS ONE, 2013-11-18;8(11):e80544.
Species: Human
Sample Types: Cell Lysates

Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy.
Authors: Necchi A, Pennati M, Zaffaroni N, Landoni E, Giannatempo P, Raggi D, Schwartz L, Morosi C, Crippa F, Fare E, Nicolai N, Lanocita R, Sava T, Sacco C, Messina C, Ortega C, De Braud F, Salvioni R, Daidone M, Gianni A, Mariani L
Br J Cancer, 2013-11-14;110(1):26-33.
Species: Human
Sample Types: Plasma

Zerumbone inhibits tumor angiogenesis via NF-kappaB in gastric cancer.
Authors: Tsuboi K, Matsuo Y, Shamoto T, Shibata T, Koide S, Morimoto M, Guha S, Sung B, Aggarwal B, Takahashi H, Takeyama H
Oncol Rep, 2013-11-11;31(1):57-64.
Species: Human
Sample Types: Cell Culture Supernates

The role of SDF-1-CXCR4/CXCR7 axis in biological behaviors of adipose tissue-derived mesenchymal stem cells in vitro.
Authors: Li Q, Zhang A, Tao C, Li X, Jin P
Biochem Biophys Res Commun, 2013-10-30;441(3):675-80.
Species: Human
Sample Types: Cell Culture Supernates

Osteosarcoma cells promote the production of pro-tumor cytokines in mesenchymal stem cells by inhibiting their osteogenic differentiation through the TGF-beta/Smad2/3 pathway.
Authors: Tu B, Peng Z, Fan Q, DU L, Yan W, Tang T
Exp Cell Res, 2013-10-30;320(1):164-73.
Species: Human
Sample Types: Cell Culture Supernates

Mobilization of circulating endothelial progenitor cells correlates with the clinical course of hantavirus disease.
Authors: Krautkramer E, Grouls S, Hettwer D, Rafat N, Tonshoff B, Zeier M
J Virol, 2013-10-23;88(1):483-9.
Species: Human
Sample Types: Plasma

DeltaNp63 promotes pediatric neuroblastoma and osteosarcoma by regulating tumor angiogenesis.
Authors: Bid, Hemant K, Roberts, Ryan D, Cam, Maren, Cam M, Audino, Anthony, Audino A, Kurmasheva, Raushan, Lin, Jiayuh, Houghton, Peter J, Cam, Hakan, Cam H
Cancer Res, 2013-10-23;74(1):320-9.
Species: Human
Sample Types: Cell Culture Supernates

Heat shock protein 27 attenuates neointima formation and accelerates reendothelialization after arterial injury and stent implantation: importance of vascular endothelial growth factor up-regulation.
Authors: Ma X, Hibbert B, McNulty M, Hu T, Zhao X, Ramirez F, Simard T, de Belleroche J, O'Brien E
FASEB J, 2013-10-18;28(2):594-602.
Species: Human
Sample Types: Cell Culture Supernates

Effects of sFlt-1 and alpha 2-macroglobulin on vascular endothelial growth factor-induced endothelin-1 upregulation in human microvascular endothelial cells.
Authors: Yi K, Jung S, Cho G, Seol H, Hong S, Oh M, Kim H
Placenta, 2013-09-25;35(1):64-9.
Species: Human
Sample Types: Cell Culture Supernates

Anticoagulation inhibits tumor cell-mediated release of platelet angiogenic proteins and diminishes platelet angiogenic response.
Authors: Battinelli, Elisabet, Markens, Beth A, Kulenthirarajan, Rajesh A, Machlus, Kellie R, Flaumenhaft, Robert, Italiano, Joseph E
Blood, 2013-09-24;123(1):101-12.
Species: Human
Sample Types: Whole Cells

BMP4/Thrombospondin-1 loop paracrinically inhibits tumor angiogenesis and suppresses the growth of solid tumors.
Authors: Tsuchida, R, Osawa, T, Wang, F, Nishii, R, Das, B, Tsuchida, S, Muramatsu, M, Takahashi, T, Inoue, T, Wada, Y, Minami, T, Yuasa, Y, Shibuya, M
Oncogene, 2013-09-09;33(29):3803-11.
Species: Human
Sample Types: Cell Culture Supernates

Advanced oxidation protein products enhances soluble Fms-like tyrosine kinase 1 expression in trophoblasts: a possible link between oxidative stress and preeclampsia.
Authors: Huang Q, Wang S, Zhang M, Huang L, Tian J, Yu Y, Wang Z, Zhong M
Placenta, 2013-07-27;34(10):949-52.
Species: Human
Sample Types: Cell Culture Supernates

Clinical outcome, proteome kinetics and angiogenic factors in serum after thermoablation of colorectal liver metastases.
Authors: Wertenbroek, Marieke, Schepers, Marianne, Kamminga-Rasker, Hannetta, Bottema, Jan T, Muller Kobold, Anneke C, Roelofsen, Han, de Jong, Koert P
BMC Cancer, 2013-05-30;13(1):266.
Species: Human
Sample Types: Serum

Dose selection trial of metronomic oral vinorelbine monotherapy in patients with metastatic cancer: a hellenic cooperative oncology group clinical translational study.
Authors: Briasoulis, Evangelo, Aravantinos, Gerasimo, Kouvatseas, George, Pappas, Periklis, Biziota, Eirini, Sainis, Ioannis, Makatsoris, Thomas, Varthalitis, Ioannis, Xanthakis, Ioannis, Vassias, Antonios, Klouvas, George, Boukovinas, Ioannis, Fountzilas, George, Syrigos, Kostanti, Kalofonos, Haralamb, Samantas, Epaminon
BMC Cancer, 2013-05-29;13(1):263.
Species: Human
Sample Types: Plasma

Subcellular localization and mechanism of secretion of vascular endothelial growth factor in human skeletal muscle.
Authors: Hoier B, Prats C, Qvortrup K, Pilegaard H, Bangsbo J, Hellsten Y
FASEB J, 2013-05-24;27(9):3496-504.
Species: Human
Sample Types: Dialysate

RUNX3 inhibits hypoxia-inducible factor-1alpha protein stability by interacting with prolyl hydroxylases in gastric cancer cells.
Authors: Lee S, Bae S, Kim K, Lee Y
Oncogene, 2013-04-01;33(11):1458-67.
Species: Human
Sample Types: Whole Cells

Epithelial membrane protein 2 controls VEGF expression in ARPE-19 cells.
Authors: Morales, Shawn A, Telander, David G, Leon, Deanna, Forward, Krisztin, Braun, Jonathan, Wadehra, Madhuri, Gordon, Lynn K
Invest Ophthalmol Vis Sci, 2013-03-28;54(3):2367-72.
Species: Human
Sample Types: Cell Culture Supernates

Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells.
Authors: Andre T, Meuleman N, Stamatopoulos B, De Bruyn C, Pieters K, Bron D, Lagneaux L
PLoS ONE, 2013-03-21;8(3):e59756.
Species: Human
Sample Types: Cell Culture Supernates

The mechanism through which octreotide inhibits hepatic stellate cell activity.
Authors: Wang J, Wang L, Song G, Han B
Mol Med Rep, 2013-03-20;7(5):1559-64.
Species: Human
Sample Types: Cell Culture Supernates

A novel splice variant of calcium and integrin-binding protein 1 mediates protein kinase D2-stimulated tumour growth by regulating angiogenesis.
Authors: Armacki, M, Joodi, G, Nimmagadda, S C, de Kimpe, L, Pusapati, G V, Vandoninck, S, Van Lint, J, Illing, A, Seufferlein, T
Oncogene, 2013-03-18;33(9):1167-80.
Species: Human
Sample Types: Cell Culture Supernates

Inhibitory effect of baicalin and baicalein on ovarian cancer cells.
Authors: Chen J, Li Z, Chen A, Ye X, Luo H, Rankin G, Chen Y
Int J Mol Sci, 2013-03-15;14(3):6012-25.
Species: Human
Sample Types: Cell Culture Supernates

Detection of rapalog-mediated therapeutic response in renal cancer xenografts using (6)(4)Cu-bevacizumab immunoPET.
Authors: Chang A, Sohn R, Lu Z, Arbeit J, Lapi S
PLoS ONE, 2013-03-14;8(0):U821.
Species: Human
Sample Types: Cell Culture Supernates

Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors.
Authors: Cerdeira A, Rajakumar A, Royle C, Lo A, Husain Z, Thadhani R, Sukhatme V, Karumanchi S, Kopcow H
J Immunol, 2013-03-13;190(8):3939-48.
Species: Human
Sample Types: Cell Culture Supernates

Angiogenic and vasculogenic factors in the vitreous from patients with proliferative diabetic retinopathy.
Authors: Abu El-Asrar, Ahmed M, Nawaz, Mohd Imt, Kangave, Dustan, Mairaj Siddiquei, Mohammed, Geboes, Karel
J Diabetes Res, 2013-03-10;0(0):539658.
Species: Human
Sample Types: Vitreous Humor

Prognostic and predictive value of VEGF, sVEGFR-2 and CEA in mCRC studies comparing cediranib, bevacizumab and chemotherapy.
Authors: Jurgensmeier J, Schmoll H, Robertson J, Brooks L, Taboada M, Morgan S, Wilson D, Hoff P
Br J Cancer, 2013-02-28;108(6):1316-23.
Species: Human
Sample Types: Plasma

Combination of albendazole and 2-methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice.
Authors: Ehteda, Anahid, Galettis, Peter, Pillai, Krishna, Morris, David L
BMC Cancer, 2013-02-23;13(0):86.
Species: Mouse
Sample Types: Plasma

Selective blockade of matrix metalloprotease-14 with a monoclonal antibody abrogates invasion, angiogenesis, and tumor growth in ovarian cancer.
Authors: Kaimal R, Aljumaily R, Tressel S, Pradhan R, Covic L, Kuliopulos A, Zarwan C, Kim Y, Sharifi S, Agarwal A
Cancer Res, 2013-02-19;73(8):2457-67.
Species: Human
Sample Types: Cell Culture Supernates

Role of serum concentration of VEGFR1 and TIMP2 on clinical outcome in primary cervical cancer: results of a companion protocol of the randomized, NOGGO-AGO phase III adjuvant trial of simultaneous cisplatin-based radiochemotherapy vs. carboplatin and paclitaxel containing sequential radiotherapy.
Authors: Braicu E, Fotopoulou C, Chekerov R, Richter R, Blohmer J, Kummel S, Stamatian F, Yalcinkaya I, Mentze M, Lichtenegger W, Sehouli J
Cytokine, 2013-02-14;61(3):755-8.
Species: Human
Sample Types: Serum

Dasatinib plus capecitabine for advanced breast cancer: safety and efficacy in phase I study CA180004.
Authors: Somlo G, Atzori F, Strauss L, Geese W, Specht J, Gradishar W, Rybicki A, Sy O, Vahdat L, Cortes J
Clin Cancer Res, 2013-02-12;19(7):1884-93.
Species: Human
Sample Types: Plasma

Impaired long-term expansion and self-renewal potential of pediatric acute myeloid leukemia-initiating cells by PTK787/ZK 222584.
Authors: Weidenaar A, Ter Elst A, Kampen K, Meeuwsen-de Boer T, Kamps W, Schuringa J, de Bont E
Mol Cancer Res, 2013-02-07;11(4):339-48.
Species: Human
Sample Types: Cell Culture Supernates

Study of the quantitative, functional, cytogenetic, and immunoregulatory properties of bone marrow mesenchymal stem cells in patients with B-cell chronic lymphocytic leukemia.
Authors: Pontikoglou C, Kastrinaki M, Klaus M, Kalpadakis C, Katonis P, Alpantaki K, Pangalis G, Papadaki H
Stem Cells Dev, 2013-02-01;22(9):1329-41.
Species: Human
Sample Types: Cell Culture Supernates

MicroRNA-16 affects key functions of human endothelial progenitor cells.
Authors: Goretti E, Rolland-Turner M, Leonard F, Zhang L, Wagner D, Devaux Y
J Leukoc Biol, 2013-01-16;93(5):645-55.
Species: Human
Sample Types: Cell Culture Supernates

Inhibition of formyl peptide receptor in high-grade astrocytoma by CHemotaxis Inhibitory Protein of S. aureus.
Authors: Boer, J C, Domanska, U M, Timmer-Bosscha, H, Boer, I G J, de Haas, C J C, Joseph, J V, Kruyt, F A E, de Vries, E G E, den Dunnen, W F A, van Strijp, J A G, Walenkamp, A M E
Br J Cancer, 2013-01-15;108(3):587-96.
Species: Human
Sample Types: Cell Culture Supernates

Transcriptional repression of VEGF by ZNF24: mechanistic studies and vascular consequences in vivo.
Authors: Jia, Di, Hasso, Sean M, Chan, Joanne, Filingeri, Domenic, D'Amore, Patricia, Rice, Lori, Pampo, Christin, Siemann, Dietmar, Zurakowski, David, Rodig, Scott J, Moses, Marsha A
Blood, 2012-12-03;121(4):707-15.
Species: Human
Sample Types: Cell Culture Supernates

Neurotensin and CRH interactions augment human mast cell activation.
Authors: Alysandratos K, Asadi S, Angelidou A, Zhang B, Sismanopoulos N, Yang H, Critchfield A, Theoharides T
PLoS ONE, 2012-11-14;7(11):e48934.
Species: Human
Sample Types: Cell Culture Supernates

A phase I trial and pharmacokinetic study of sorafenib in children with refractory solid tumors or leukemias: a Children's Oncology Group Phase I Consortium report.
Authors: Widemann B, Kim A, Fox E, Baruchel S, Adamson P, Ingle A, Glade Bender J, Burke M, Weigel B, Stempak D, Balis F, Blaney S
Clin Cancer Res, 2012-09-07;18(21):6011-22.
Species: Human
Sample Types: Plasma

Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer.
Clin. Cancer Res., 2012-07-24;18(18):5031-42.
Species: Human
Sample Types: Plasma

Met Receptor Tyrosine Kinase Signaling Induces Secretion of the Angiogenic Chemokine Interleukin-8/CXCL8 in Pancreatic Cancer.
Authors: Hill KS, Gaziova I, Harrigal L
PLoS ONE, 2012-07-17;7(7):e40420.
Species: Human
Sample Types: Cell Culture Supernates

XELIRI-bevacizumab versus FOLFIRI-bevacizumab as first-line treatment in patients with metastatic colorectal cancer: a Hellenic Cooperative Oncology Group phase III trial with collateral biomarker analysis.
BMC Cancer, 2012-06-29;12(0):271.
Species: Human
Sample Types: Plasma

Measuring urinary tubular biomarkers in type 2 diabetes does not add prognostic value beyond established risk factors.
Kidney Int, 2012-06-20;82(7):812-8.
Species: Human
Sample Types: Serum

Phase I trial of combretastatin A4 phosphate (CA4P) in combination with bevacizumab in patients with advanced cancer.
Clin. Cancer Res., 2012-05-29;18(12):3428-39.
Species: Human
Sample Types: Plasma

Comparison of the levels of the growth factors in umbilical cord serum and human milk and its clinical significance.
Authors: Patki S, Patki U, Patil R, Indumathi S, Kaingade P, Bulbule A, Nikam A, Pishte A
Cytokine, 2012-05-19;59(2):305-8.
Species: Human
Sample Types: Serum

Serum neurotensin (NT) is increased in psoriasis and NT induces vascular endothelial growth factor release from human mast cells.
Authors: Vasiadi M, Therianou A, Alysandratos KD, Katsarou-Katsari A, Petrakopoulou T, Theoharides A, Papadavid E, Stavrianeas N, Antoniou C, Kalogeromitros D, Theoharides TC
Br. J. Dermatol., 2012-05-14;166(6):1349-52.
Species: Human
Sample Types: Cell Culture Supernates

Cardiac angiogenic imbalance leads to peripartum cardiomyopathy.
Authors: Patten IS, Rana S, Shahul S, Rowe GC, Jang C, Liu L, Hacker MR, Rhee JS, Mitchell J, Mahmood F, Hess P, Farrell C, Koulisis N, Khankin EV, Burke SD, Tudorache I, Bauersachs J, del Monte F, Hilfiker-Kleiner D, Karumanchi SA, Arany Z
Nature, 2012-05-09;485(7398):333-8.
Species: Human
Sample Types: Plasma

Semaphorin 4A exerts a proangiogenic effect by enhancing vascular endothelial growth factor-A expression in macrophages.
Authors: Meda C, Molla F, De Pizzol M
J. Immunol., 2012-03-21;188(8):4081-92.
Species: Human
Sample Types: Cell Culture Supernates

Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma.
Authors: Llovet JM, Pena CE, Lathia CD, Shan M, Meinhardt G, Bruix J, Pallota MG, Zarba JJ, Boyer M, Riordan S, Strickland A, Tebbutt N, Thomson B, Borbath I, De Greve J, Van Laethem J-, Van Steenbergen W, Van Vlierberghe H, Barrios C, Cosme de Oliveira A, Kotzev I, Takov D, Tchernev K, Burak K, Ma M, Metrakos P, Olweny C, Sherman M, Gamargo Garate C, Martinez-Castillo J, Beaugrand M, Bennouna J, Blanc J-, Bronowicki J-, Degos F, Dominguez S, Grange J-, Hillon P, Raoul J-, Seitz J-, Blum H, Buggisch P, Caspary W, Dollinger M, Gerken G, Goke B, Gregor M, Greten T, Haussinger D, Hilgard P, ScherÃƒÂ¼bl J, Scheulen M, Schmid R, Spengler U, Wiest R, Zeuzem S, Arvanitakis C, Germanidis G, Katsos I, Figer A, Stemmer S, Amadori D, Bolondi L, Cognetti F, Craxi A, Farinati F, Gridelli C, Martoni A, Mazzaferro V, Porta C, Ricci S, Sangiovanni A, Santoro A, Trevisani F, Cisnero Garza LE, Gane E, O'Donnell A, Leon J, Lozano A, Jassem J, Rydzewska G, Szawlowski A, Tomczak P, Badulescu F, Miron L, Kubyshkin V, Bruix J, Forner A, Bustamante Schneider J, Diago M, Montero Alvarez JL, Pascual S, RuÃƒÂz del Arbol L, Sangro B, SolÃƒÂ¡ R, Tabernero J, Muellhaupt B, Roth A, Jeffry Evans TR, Falk S, Meyer T, Reeves H, Ross P, Befeler A, Boyer T, Britten C, Byrne T, Garcia-Tsao G, Gold P, Goldenberg A, Heuman D, Kennedy P, Koch A, Llovet JM, Marrero J, Schilsky M, Schwartz J, Schwartz M
Clin. Cancer Res., 2012-02-28;18(8):2290-300.
Species: Human
Sample Types: Plasma

Biomarkers for antitumor activity of bevacizumab in gastric cancer models.
Authors: Yamashita-Kashima Y, Fujimoto-Ouchi K, Yorozu K, Kurasawa M, Yanagisawa M, Yasuno H, Mori K
BMC Cancer, 2012-01-25;12(0):37.
Species: Human
Sample Types: Tissue Homogenates

Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.
Authors: Dupuy S, Lambert M, Zucman D, Choukem SP, Tognarelli S, Pages C, Lebbe C, Caillat-Zucman S
PLoS Pathog., 2012-01-12;8(1):e1002486.
Species: Human
Sample Types: Cell Culture Supernates

Late SV40 factor (LSF) enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (MMP-9).
Authors: Santhekadur PK, Gredler R, Chen D
J. Biol. Chem., 2011-12-13;287(5):3425-32.
Species: Human
Sample Types: Cell Culture Supernates

Bevacizumab attenuates major signaling cascades and eIF4E translation initiation factor in multiple myeloma cells.
Authors: Attar-Schneider O, Drucker L, Zismanov V
Lab. Invest., 2011-11-14;92(2):178-90.
Species: Human
Sample Types: Cell Culture Supernates

Stromal interaction essential for vascular endothelial growth factor A-induced tumour growth via transforming growth factor-beta signalling.
Authors: Weidenaar AC, Ter Elst A, Kampen KR, Meeuwsen-de Boer TG, de Jonge HJ, Scherpen FJ, den Dunnen WF, Kamps WA, de Bont ES
Br. J. Cancer, 2011-11-01;105(12):1856-63.
Species: Human
Sample Types: Cell Culture Supernates

Thrombospondin-1 triggers cell migration and development of advanced prostate tumors.
Authors: Firlej V, Mathieu JR, Gilbert C, Lemonnier L, Nakhle J, Gallou-Kabani C, Guarmit B, Morin A, Prevarskaya N, Delongchamps NB, Cabon F
Cancer Res., 2011-10-28;71(24):7649-58.
Species: Human
Sample Types: Cell Lysates

Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells.
Authors: McGuire TR, Brusnahan SK, Bilek LD, Jackson JD, Kessinger MA, Berger AM, Garvin KL, O'Kane BJ, Tuljapurkar SR, Sharp JG
Obesity (Silver Spring), 2011-09-08;19(11):2130-6.
Species: Human
Sample Types: Plasma

Prognostic significance of angiogenic factors in uterine cervical cancer.
Authors: Landt S, Wehling M, Heidecke H, Jeschke S, Korlach S, Stoblen F, Schmid P, Blohmer JU, Lichtenegger W, Sehouli J, Kummel S
Anticancer Res., 2011-08-01;31(8):2589-95.
Species: Human
Sample Types: Serum

In vitro vascular tube formation testing as a tool for treatment individualisation in patients with cervical cancer.
Authors: Landt S, Heidecke H, Korlach S, Reuter C, Schwidde I, Barinoff J, Thill M, Sehouli J, Kummel S
Anticancer Res., 2011-08-01;31(8):2609-15.
Species: Human
Sample Types: Serum

Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib.
Authors: Harmon CS, DePrimo SE, Raymond E, Cheng AL, Boucher E, Douillard JY, Lim HY, Kim JS, Lechuga MJ, Lanzalone S, Lin X, Faivre S
J Transl Med, 2011-07-25;9(0):120.
Species: Human
Sample Types: Plasma

Macrophage infiltration predicts a poor prognosis for human ewing sarcoma.
Authors: Fujiwara T, Fukushi J, Yamamoto S, Matsumoto Y, Setsu N, Oda Y, Yamada H, Okada S, Watari K, Ono M, Kuwano M, Kamura S, Iida K, Okada Y, Koga M, Iwamoto Y
Am. J. Pathol., 2011-07-21;179(3):1157-70.
Species: Human
Sample Types: Cell Culture Supernates

Pertuzumab in combination with trastuzumab shows significantly enhanced antitumor activity in HER2-positive human gastric cancer xenograft models.
Authors: Yamashita-Kashima Y, Iijima S, Yorozu K, Furugaki K, Kurasawa M, Ohta M, Fujimoto-Ouchi K
Clin. Cancer Res., 2011-06-23;17(15):5060-70.
Species: Human
Sample Types: Tissue Homogenates

Serum levels of beta-catenin as a potential marker for genotype 4/hepatitis C-associated hepatocellular carcinoma.
Authors: Zekri A, Bahnassy A, Alam El-Din H, Morsy H, Shaarawy S, Moharram N, Daoud S
Oncol Rep, 2011-06-21;26(4):825-31.
Species: Human
Sample Types: Serum

Phase I and pharmacokinetic study of sunitinib in pediatric patients with refractory solid tumors: a children's oncology group study.
Authors: Dubois SG, Shusterman S, Ingle AM, Ahern CH, Reid JM, Wu B, Baruchel S, Glade-Bender J, Ivy P, Grier HE, Adamson PC, Blaney SM
Clin. Cancer Res., 2011-06-20;17(15):5113-22.
Species: Human
Sample Types: Plasma

Leptin administered in physiological or pharmacological doses does not regulate circulating angiogenesis factors in humans.
Authors: Aronis KN, Diakopoulos KN, Fiorenza CG
Diabetologia, 2011-06-10;54(9):2358-67.
Species: Human
Sample Types: Serum

Myeloid Biomarkers Associated with Glioblastoma Response to Anti-VEGF Therapy with Aflibercept.
Authors: de Groot JF, Piao Y, Tran H, Gilbert M, Wu HK, Liu J, Bekele BN, Cloughesy T, Mehta M, Robins HI, Lassman A, Deangelis L, Camphausen K, Chen A, Yung W, Prados M, Wen PY, Heymach JV
Clin. Cancer Res., 2011-06-01;17(14):4872-4881.
Species: Human
Sample Types: Plasma

Vascular endothelial growth factor-A (VEGF-A) and chemokine ligand-2 (CCL2) in Amyotrophic Lateral Sclerosis (ALS) patients.
Authors: Gupta PK, Prabhakar S
J Neuroinflammation, 2011-05-13;8(1):47.
Species: Human
Sample Types: Serum

CD34+ progenitor cells likely are involved in the good functional recovery after intracerebral hemorrhage in humans.
Authors: Sobrino T, Arias S, Perez-Mato M, Agulla J, Brea D, Rodriguez-Yanez M, Castillo J
J. Neurosci. Res., 2011-04-12;89(7):979-85.
Species: Human
Sample Types: Serum

Pharmacodynamic and pharmacogenetic angiogenesis-related markers of first-line FOLFOXIRI plus bevacizumab schedule in metastatic colorectal cancer.
Authors: Loupakis F, Cremolini C, Fioravanti A
Br. J. Cancer, 2011-03-15;104(8):1262-9.
Species: Human
Sample Types: Plasma

Levels of circulating CD45(dim)CD34(+)VEGFR2(+) progenitor cells correlate with outcome in metastatic renal cell carcinoma patients treated with tyrosine kinase inhibitors.
Authors: Farace F, Gross-Goupil M, Tournay E, Taylor M, Vimond N, Jacques N, Billiot F, Mauguen A, Hill C, Escudier B
Br. J. Cancer, 2011-03-08;104(7):1144-50.
Species: Human
Sample Types: Plasma

Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities.
Authors: Farha S, Asosingh K, Xu W, Sharp J, George D, Comhair S, Park M, Tang WH, Loyd JE, Theil K, Tubbs R, Hsi E, Lichtin A, Erzurum SC
Blood, 2011-01-21;117(13):3485-93.
Species: Human
Sample Types: Plasma

Hypoxia potentiates glioma-mediated immunosuppression.
Authors: Wei J, Wu A, Kong LY, Wang Y, Fuller G, Fokt I, Melillo G, Priebe W, Heimberger AB
PLoS ONE, 2011-01-20;6(1):e16195.
Species: Human
Sample Types: Cell Culture Supernates

Synergistic effects of imatinib and carboplatin on VEGF, PDGF and PDGF-Ralpha/beta expression in squamous cell carcinoma of the head and neck in vitro.
Authors: Schultz JD, Rotunno S, Riedel F, Anders C, Erben P, Hofheinz RD, Faber A, Thorn C, Sommer JU, Hormann K, Sauter A
Int. J. Oncol., 2011-01-18;38(4):1001-12.
Species: Human
Sample Types: Cell Lysates

Alternatives to the use of fetal bovine serum: human platelet lysates as a serum substitute in cell culture media.
Authors: Rauch C, Feifel E, Amann EM, Spotl HP, Schennach H, Pfaller W, Gstraunthaler G
ALTEX, 2011-01-01;28(4):305-16.
Species: Human
Sample Types: Cell Lysates

Association of angiopoietin-2, C-reactive protein and markers of obesity and insulin resistance with survival outcome in colorectal cancer.
Authors: Volkova E, Willis JA, Wells JE, Robinson BA, Dachs GU, Currie MJ
Br. J. Cancer, 2010-11-16;104(1):51-9.
Species: Human
Sample Types: Serum

Endocrine gland-derived vascular endothelial growth factor concentrations in follicular fluid and serum may predict ovarian hyperstimulation syndrome in women undergoing controlled ovarian hyperstimulation.
Authors: Gao MZ, Zhao XM, Sun ZG
Fertil. Steril., 2010-11-10;95(2):673-8.
Species: Human
Sample Types: Serum

Placental growth factor neutralising antibodies give limited anti-angiogenic effects in an in vitro organotypic angiogenesis model.
Authors: Brave SR, Eberlein C, Shibuya M, Wedge SR, Barry ST
Angiogenesis, 2010-10-16;13(4):337-47.
Species: Human
Sample Types: Cell Culture Supernates

Stromal cell-derived factor-1 is essential for photoreceptor cell protection in retinal detachment.
Authors: Otsuka H, Arimura N, Sonoda S
Am. J. Pathol., 2010-10-01;177(5):2268-77.
Species: Human
Sample Types: Vitreous Humor

Plasma haemoxygenase-1 in coronary artery disease. A comparison with angiogenin, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1 and vascular endothelial growth factor.
Authors: Idriss NK, Lip GY, Balakrishnan B
Thromb. Haemost., 2010-09-13;104(5):1029-37.
Species: Human
Sample Types: Plasma

Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair.
Authors: Li TS, Cheng K, Malliaras K, Matsushita N, Sun B, Marban L, Zhang Y, Marban E
Cardiovasc. Res., 2010-07-29;89(1):157-65.
Species: Human
Sample Types: Cell Culture Supernates

The transcription factor E2F1 and the SR protein SC35 control the ratio of pro-angiogenic versus antiangiogenic isoforms of vascular endothelial growth factor-A to inhibit neovascularization in vivo.
Authors: Merdzhanova G, Gout S, Keramidas M, Edmond V, Coll JL, Brambilla C, Brambilla E, Gazzeri S, Eymin B
Oncogene, 2010-07-19;29(39):5392-403.
Species: Human
Sample Types: Cell Culture Supernates

Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch.
Authors: Ding W, Knox TR, Tschumper RC
Blood, 2010-07-06;116(16):2984-93.
Species: Human
Sample Types: Platelet Poor Plasma

Dissecting the effects of lipopolysaccharides from nonlipopolysaccharide molecules in experimental porcine meningococcal sepsis.
Authors: Hellerud BC, Nielsen EW, Thorgersen EB, Lindstad JK, Pharo A, Tonnessen TI, Castellheim A, Mollnes TE, Brandtzaeg P
Crit. Care Med., 2010-06-01;38(6):1467-74.
Species: Porcine
Sample Types: Plasma

Macrophage inhibitory cytokine-1 regulates melanoma vascular development.
Authors: Huh SJ, Chung CY, Sharma A
Am. J. Pathol., 2010-04-29;176(6):2948-57.
Species: Human
Sample Types: Serum

Angiopoietin-2 plasma dosage predicts time to first treatment and overall survival in chronic lymphocytic leukemia.
Authors: Maffei R, Martinelli S, Santachiara R
Blood, 2010-04-09;116(4):584-92.
Species: Human
Sample Types: Plasma

Cationic liposome coupled endostatin gene for treatment of peritoneal colon cancer.
Authors: Lan KL, Ou-Yang F, Yen SH, Shih HL, Lan KH
Clin. Exp. Metastasis, 2010-04-07;27(5):307-18.
Species: Human
Sample Types: Ascites Fluid

Extended ischemia prevents HIF1alpha degradation at reoxygenation by impairing prolyl-hydroxylation: role of Krebs cycle metabolites.
Authors: Serra-Perez A, Planas AM, NÃºÃ±ez-O'Mara A, Berra E, Garcia-Villoria J, Ribes A, Santalucia T
J. Biol. Chem., 2010-04-05;285(24):18217-24.
Species: Human
Sample Types: Cell Culture Supernates

Phase 1/2 study of preoperative docetaxel and mitoxantrone for high-risk prostate cancer.
Authors: Garzotto M, Higano CS, O'Brien C, Rademacher BL, Janeba N, Fazli L, Lange PH, Lieberman S, Beer TM
Cancer, 2010-04-01;116(7):1699-708.
Species: Human
Sample Types: Plasma

Differential effect of ischaemic preconditioning on mobilisation and recruitment of haematopoietic and mesenchymal stem cells in porcine myocardial ischaemia-reperfusion.
Authors: Gyongyosi M, Posa A, Pavo N, Hemetsberger R, Kvakan H, Steiner-Boker S, Petrasi Z, Manczur F, Pavo IJ, Edes IF, Wojta J, Glogar D, Huber K
Thromb. Haemost., 2010-03-29;104(2):376-84.
Species: Human
Sample Types: Plasma

Defective angiogenesis in hypoplastic human fetal lungs correlates with nitric oxide synthase deficiency that occurs despite enhanced angiopoietin-2 and VEGF.
Authors: Boucherat O, Franco-Montoya ML, Delacourt C, Martinovic J, Masse V, Elie C, Thebaud B, Benachi A, Bourbon JR
Am. J. Physiol. Lung Cell Mol. Physiol., 2010-03-26;298(6):L849-56.
Species: Human
Sample Types: Tissue Homogenates

Human pregnancy specific beta-1-glycoprotein 1 (PSG1) has a potential role in placental vascular morphogenesis.
Authors: Ha CT, Wu JA, Irmak S, Lisboa FA, Dizon AM, Warren JW, Ergun S, Dveksler GS
Biol. Reprod., 2010-03-24;83(1):27-35.
Species: Human
Sample Types: Cell Culture Supernates

Inhibition of EGFR pathway signaling and the metastatic potential of breast cancer cells by PA-MSHA mediated by type 1 fimbriae via a mannose-dependent manner.
Authors: Liu ZB, Hou YF, Zhu J
Oncogene, 2010-03-15;29(20):2996-3009.
Species: Human
Sample Types: Cell Culture Supernates

Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.
Authors: Nilsson MB, Zage PE, Zeng L, Xu L, Cascone T, Wu HK, Saigal B, Zweidler-McKay PA, Heymach JV
Oncogene, 2010-03-08;29(20):2938-49.
Species: Human
Sample Types: Cell Culture Supernates

VEGF-mediated angiogenesis stimulates neural stem cell proliferation and differentiation in the premature brain.
Authors: Sun J, Sha B, Zhou W, Yang Y
Biochem. Biophys. Res. Commun., 2010-02-24;394(1):146-52.
Species: Human
Sample Types: Cell Culture Supernates

Inhibition of cancer cell proliferation and metastasis by insulin receptor downregulation.
Authors: Zhang H, Fagan DH, Zeng X
Oncogene, 2010-02-15;29(17):2517-27.
Species: Human
Sample Types: Cell Culture Supernates

Effect of intensive lifestyle changes on endothelial function and on inflammatory markers of atherosclerosis.
Authors: Dod HS, Bhardwaj R, Sajja V, Weidner G, Hobbs GR, Konat GW, Manivannan S, Gharib W, Warden BE, Nanda NC, Beto RJ, Ornish D, Jain AC
Am. J. Cardiol., 2010-02-01;105(3):362-7.
Species: Human
Sample Types: Serum

VEGF-A promotes lymphoma tumour growth by activation of STAT proteins and inhibition of p27(KIP1) via paracrine mechanisms.
Authors: Roorda BD, Ter Elst A, Scherpen FJ, Meeuwsen-de Boer TG, Kamps WA, de Bont ES
Eur. J. Cancer, 2010-01-22;46(5):974-82.
Species: Human
Sample Types: Plasma

A phase I trial of bortezomib with temozolomide in patients with advanced melanoma: toxicities, antitumor effects, and modulation of therapeutic targets.
Authors: Su Y, Amiri KI, Horton LW
Clin. Cancer Res., 2009-12-22;16(1):348-57.
Species: Human
Sample Types: Serum

Vitreous VEGF clearance is increased after vitrectomy.
Authors: Lee SS, Ghosn C, Yu Z, Zacharias LC, Kao H, Lanni C, Abdelfattah N, Kuppermann B, Csaky KG, D'Argenio DZ, Burke JA, Hughes PM, Robinson MR
Invest. Ophthalmol. Vis. Sci., 2009-12-17;51(4):2135-8.
Species: Rabbit
Sample Types: Vitreous Humor

Soluble Flt-1 gene therapy ameliorates albuminuria but accelerates tubulointerstitial injury in diabetic mice.
Authors: Kosugi T, Nakayama T, Li Q, Chiodo VA, Zhang L, Campbell-Thompson M, Grant M, Croker BP, Nakagawa T
Am. J. Physiol. Renal Physiol., 2009-12-16;298(3):F609-16.
Species: Human
Sample Types: Serum

The change of cytokines in tear and blood after different pterygium operation.
Authors: Lee JK, Song YS, Shin JS, Kwon YS, Shin MS, Kim JC
Cytokine, 2009-12-08;49(2):148-54.
Species: Human
Sample Types: Tears

Sensitive plasma protein analysis by microparticle-based proximity ligation assays.
Authors: Darmanis S, Nong RY, Hammond M, Gu J, Alderborn A, Vanelid J, Siegbahn A, Gustafsdottir S, Ericsson O, Landegren U, Kamali-Moghaddam M
Mol. Cell Proteomics, 2009-11-27;9(2):327-35.
Species: Human
Sample Types: Plasma

Distraction osteogenesis induces endothelial progenitor cell mobilization without inflammatory response in man.
Authors: Lee DY, Cho TJ, Lee HR, Park MS, Yoo WJ, Chung CY, Choi IH
Bone, 2009-10-22;46(3):673-9.
Species: Human
Sample Types: Plasma

CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs.
Authors: Thorgersen EB, Hellerud BC, Nielsen EW, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Fosse E, Tonnessen TI, Johansen HT, Castellheim A, Mollnes TE
FASEB J., 2009-10-19;24(3):712-22.
Species: Porcine
Sample Types: Plasma

Vascular endothelial growth factor as an autocrine survival factor for retinal pigment epithelial cells under oxidative stress via the VEGF-R2/PI3K/Akt.
Authors: Byeon SH, Lee SC, Choi SH, Lee HK, Lee JH, Chu YK, Kwon OW
Invest. Ophthalmol. Vis. Sci., 2009-10-15;51(2):1190-7.
Species: Human
Sample Types: Cell Culture Supernates

Vascular endothelial growth factor drives autocrine epithelial cell proliferation and survival in chronic rhinosinusitis with nasal polyposis.
Authors: Lee HS, Myers A, Kim J
Am. J. Respir. Crit. Care Med., 2009-09-17;180(11):1056-67.
Species: Human
Sample Types: Nasal Lavage Fluid

Hyperoxia disrupts vascular endothelial growth factor-nitric oxide signaling and decreases growth of endothelial colony-forming cells from preterm infants.
Authors: Fujinaga H, Baker CD, Ryan SL, Markham NE, Seedorf GJ, Balasubramaniam V, Abman SH
Am. J. Physiol. Lung Cell Mol. Physiol., 2009-09-04;297(6):L1160-9.
Species: Human
Sample Types: Cell Culture Supernates

Age-dependent mobilization of circulating endothelial progenitor cells in infants and young children undergoing cardiac surgery with cardiopulmonary bypass.
Authors: Sun Y, Yi D, Wang Y, Zheng R, Sun G, Wang J, Liu Y, Ren J, Wang Y, Zhang S, Gu C, Pei J
Cytokine, 2009-07-24;47(3):206-13.
Species: Human
Sample Types: Plasma

Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy.
Authors: Lucio-Eterovic AK, Piao Y, de Groot JF
Clin. Cancer Res., 2009-06-30;15(14):4589-99.
Species: Human
Sample Types: Cell Culture Supernates

Effects of the menstrual cycle on lung function variables in women with asthma.
Authors: Farha S, Asosingh K, Laskowski D, Hammel J, Dweik RA, Wiedemann HP, Erzurum SC
Am. J. Respir. Crit. Care Med., 2009-06-11;180(4):304-10.
Species: Human
Sample Types: Serum

Colorectal resection is associated with persistent proangiogenic plasma protein changes: postoperative plasma stimulates in vitro endothelial cell growth, migration, and invasion.
Authors: Shantha Kumara HM, Feingold D, Kalady M, Dujovny N, Senagore A, Hyman N, Cekic V, Whelan RL
Ann. Surg., 2009-06-01;249(6):973-7.
Species: Human
Sample Types: Plasma

Inhibition of vascular endothelial growth factor reduces scar formation after glaucoma filtration surgery.
Authors: Li Z, Van Bergen T, Van de Veire S, Van de Vel I, Moreau H, Dewerchin M, Maudgal PC, Zeyen T, Spileers W, Moons L, Stalmans I
Invest. Ophthalmol. Vis. Sci., 2009-05-27;50(11):5217-25.
Species: Human
Sample Types: Aqueous Humor

A phase II trial of single agent bevacizumab in patients with relapsed, aggressive non-Hodgkin lymphoma: Southwest oncology group study S0108.
Authors: Stopeck AT, Unger JM, Rimsza LM, Bellamy WT, Iannone M, Persky DO, Leblanc M, Fisher RI, Miller TP
Leuk. Lymphoma, 2009-05-01;50(5):728-35.
Species: Human
Sample Types: Urine

Signs of reduced angiogenic activity after surgical removal of deeply infiltrating endometriosis.
Authors: Bourlev V, Iljasova N, Adamyan L, Larsson A, Olovsson M
Fertil. Steril., 2009-03-25;94(1):52-7.
Species: Human
Sample Types: Serum

Cytokine secretion by human mesenchymal stem cells cocultured with damaged corneal epithelial cells.
Authors: Oh JY, Kim MK, Shin MS, Wee WR, Lee JH
Cytokine, 2009-02-14;46(1):100-3.
Species: Human
Sample Types: Cell Culture Supernates

Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes.
Authors: Rodriguez PC, Ernstoff MS, Hernandez C, Atkins M, Zabaleta J, Sierra R, Ochoa AC
Cancer Res., 2009-02-05;69(4):1553-60.
Species: Human
Sample Types: Plasma

Are plasma VEGF and its soluble receptor sFlt-1 atherogenic risk factors? Cross-sectional data from the SAPHIR study.
Authors: Sandhofer A, Tatarczyk T, Kirchmair R, Iglseder B, Paulweber B, Patsch JR, Schratzberger P
Atherosclerosis, 2009-02-03;206(1):265-9.
Species: Human
Sample Types: Plasma

A small-molecule triptolide suppresses angiogenesis and invasion of human anaplastic thyroid carcinoma cells via down-regulation of the nuclear factor-kappa B pathway.
Authors: Zhu W, Ou Y, Li Y, Xiao R, Shu M, Zhou Y, Xie J, He S, Qiu P, Yan G
Mol. Pharmacol., 2009-01-21;75(4):812-9.
Species: Human
Sample Types: Cell Culture Supernates

Interleukin-32 promotes osteoclast differentiation but not osteoclast activation.
Authors: Mabilleau G, Sabokbar A
PLoS ONE, 2009-01-12;4(1):e4173.
Species: Human
Sample Types: Cell Culture Supernates

Changes in vascular endothelial growth factor, angiopoietins, and Tie-2 levels with G-CSF stimulation in healthy donors.
Authors: Serefhanoglu S, Goker H, Buyukasik Y, Turgut M, Sayinalp N, Haznedaroglu IC, Aksu S, Akman U, Ozcebe OI
Ann. Hematol., 2008-12-11;88(7):667-71.
Species: Human
Sample Types: Plasma

Inhibition of complement and CD14 attenuates the Escherichia coli-induced inflammatory response in porcine whole blood.
Authors: Thorgersen EB, Pharo A, Haverson K, Axelsen AK, Gaustad P, Kotwal GJ, Sfyroera G, Mollnes TE
Infect. Immun., 2008-12-01;77(2):725-32.
Species: Porcine
Sample Types: Whole Blood

Differential regulation of VEGF after final oocyte maturation with GnRH agonist versus hCG: a rationale for OHSS reduction.
Authors: Cerrillo M, Rodriguez S, Mayoral M, Pacheco A, Martinez-Salazar J, Garcia-Velasco JA
Fertil. Steril., 2008-11-05;91(4):1526-8.
Species: Human
Sample Types: Plasma

Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria.
Authors: Yeo TW, Lampah DA, Gitawati R, Tjitra E, Kenangalem E, Piera K, Price RN, Duffull SB, Celermajer DS, Anstey NM
Proc. Natl. Acad. Sci. U.S.A., 2008-10-28;105(44):17097-102.
Species: Human
Sample Types: Plasma

Endothelial progenitor cell levels in obese men with the metabolic syndrome and the effect of simvastatin monotherapy vs. simvastatin/ezetimibe combination therapy.
Authors: Westerweel PE, Visseren FL, Hajer GR, Olijhoek JK, Hoefer IE, de Bree P, Rafii S, Doevendans PA, Verhaar MC
Eur. Heart J., 2008-09-28;29(22):2808-17.
Species: Human
Sample Types: Serum

Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents.
Authors: Shaked Y, Henke E, Roodhart JM, Mancuso P, Langenberg MH, Colleoni M, Daenen LG, Man S, Xu P, Emmenegger U, Tang T, Zhu Z, Witte L, Strieter RM, Bertolini F, Voest EE, Benezra R, Kerbel RS
Cancer Cell, 2008-09-09;14(3):263-73.
Species: Human
Sample Types: Plasma

Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma.
Authors: Rini BI, Michaelson MD, Rosenberg JE, Bukowski RM, Sosman JA, Stadler WM, Hutson TE, Margolin K, Harmon CS, DePrimo SE, Kim ST, Chen I, George DJ
J. Clin. Oncol., 2008-08-01;26(22):3743-8.
Species: Human
Sample Types: Plasma

Endometrial NK cells are special immature cells that await pregnancy.
Authors: Manaster I, Mizrahi S, Goldman-Wohl D, Sela HY, Stern-Ginossar N, Lankry D, Gruda R, Hurwitz A, Bdolah Y, Haimov-Kochman R, Yagel S, Mandelboim O
J. Immunol., 2008-08-01;181(3):1869-76.
Species: Human
Sample Types: Cell Culture Supernates

Plasma levels of soluble Tie2 and vascular endothelial growth factor distinguish critical limb ischemia from intermittent claudication in patients with peripheral arterial disease.
Authors: Findley CM, Mitchell RG, Duscha BD, Annex BH, Kontos CD
J. Am. Coll. Cardiol., 2008-07-29;52(5):387-93.
Species: Human
Sample Types: Plasma

Pulmonary arterial hypertension and left-sided heart disease in sickle cell disease: clinical characteristics and association with soluble adhesion molecule expression.
Authors: Klings ES, Anton Bland D, Rosenman D, Princeton S, Odhiambo A, Li G, Bernard SA, Steinberg MH, Farber HW
Am. J. Hematol., 2008-07-01;83(7):547-53.
Species: Human
Sample Types: Plasma

Angiopoietin-2, permeability oedema, occurrence and severity of ALI/ARDS in septic and non-septic critically ill patients.
Authors: van der Heijden M, van Nieuw Amerongen GP, Koolwijk P, van Hinsbergh VW, Groeneveld AB
Thorax, 2008-06-17;63(10):903-9.
Species: Human
Sample Types: Plasma

Aggressive melanoma cells escape from BMP7-mediated autocrine growth inhibition through coordinated Noggin upregulation.
Authors: Hsu MY, Rovinsky SA, Lai CY, Qasem S, Liu X, How J, Engelhardt JF, Murphy GF
Lab. Invest., 2008-06-16;88(8):842-55.
Species: Human
Sample Types: Cell Lysates

Oncogenic and angiogenic growth factors accumulate during routine storage of apheresis platelet concentrates.
Authors: Kanter J, Khan SY, Kelher M, Gore L, Silliman CC
Clin. Cancer Res., 2008-06-15;14(12):3942-7.
Species: Human
Sample Types: Platelet Poor Plasma

Improved prediction of disease relapse after radical prostatectomy through a panel of preoperative blood-based biomarkers.
Authors: Shariat SF, Karam JA, Walz J, Roehrborn CG, Montorsi F, Margulis V, Saad F, Slawin KM, Karakiewicz PI
Clin. Cancer Res., 2008-06-15;14(12):3785-91.
Species: Human
Sample Types: Plasma

VEGF-D promotes tumor growth and lymphatic spread in a mouse model of hepatocellular carcinoma.
Authors: Thelen A, Scholz A, Benckert C, Von Marschall Z, Schroder M, Wiedenmann B, Neuhaus P, Rosewicz S, Jonas S
Int. J. Cancer, 2008-06-01;122(11):2471-81.
Species: Human
Sample Types: Cell Culture Supernates

Late outgrowth endothelial progenitor cells in patients with age-related macular degeneration.
Authors: Thill M, Strunnikova NV, Berna MJ, Gordiyenko N, Schmid K, Cousins SW, Thompson DJ, Csaky KG
Invest. Ophthalmol. Vis. Sci., 2008-06-01;49(6):2696-708.
Species: Human
Sample Types: Plasma

Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.
Authors: Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, Fatica A, Negrini M, Peschle C, Valtieri M
Exp. Hematol., 2008-05-27;36(8):1035-46.
Species: Human
Sample Types: Cell Culture Supernates

Vascular endothelial growth factor-A stimulates Snail expression in breast tumor cells: implications for tumor progression.
Authors: Wanami LS, Chen HY, Peiro S, Garcia de Herreros A, Bachelder RE
Exp. Cell Res., 2008-05-17;314(13):2448-53.
Species: Human
Sample Types: Cell Lysates

Tamoxifen and aromatase inhibitors differentially affect vascular endothelial growth factor and endostatin levels in women with breast cancer.
Authors: Holmes CE, Huang JC, Pace TR, Howard AB, Muss HB
Clin. Cancer Res., 2008-05-15;14(10):3070-6.
Species: Human
Sample Types: Plasma

Neural stem/progenitor cells promote endothelial cell morphogenesis and protect endothelial cells against ischemia via HIF-1alpha-regulated VEGF signaling.
Authors: Roitbak T, Li L, Cunningham LA
J. Cereb. Blood Flow Metab., 2008-05-14;28(9):1530-42.
Species: Human
Sample Types: Cell Culture Supernates

Hypoxia induces leptin gene expression and secretion in human preadipocytes: differential effects of hypoxia on adipokine expression by preadipocytes.
Authors: Wang B, Wood IS, Trayhurn P
J. Endocrinol., 2008-05-07;198(1):127-34.
Species: Human
Sample Types: Cell Culture Supernates

Structural stability of neoangiogenic intramyocardial microvessels supports functional recovery in chronic ischemic myocardium.
Authors: Shim WS, Lim SY, Li SQ, Gu Y, Ong HC, Song IC, Chuah SC, Wong P
J. Mol. Cell. Cardiol., 2008-04-27;45(1):70-80.
Species: Porcine
Sample Types: Tissue Homogenates

Comparison of bevacizumab, ranibizumab, and pegaptanib in vitro: efficiency and possible additional pathways.
Authors: Klettner A, Roider J
Invest. Ophthalmol. Vis. Sci., 2008-04-25;49(10):4523-7.
Species: Porcine
Sample Types: Cell Culture Supernates

Urinary biomarkers predict brain tumor presence and response to therapy.
Authors: Smith ER, Zurakowski D, Saad A, Scott RM, Moses MA
Clin. Cancer Res., 2008-04-15;14(8):2378-86.
Species: Human
Sample Types: Urine

Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane.
Authors: Burstein HJ, Elias AD, Rugo HS, Cobleigh MA, Wolff AC, Eisenberg PD, Lehman M, Adams BJ, Bello CL, DePrimo SE, Baum CM, Miller KD
J. Clin. Oncol., 2008-03-17;26(11):1810-6.
Species: Human
Sample Types: Plasma

Regulation of vascular endothelial growth factor-A and its soluble receptor sFlt-1 by luteinizing hormone in vivo: implication for ovarian follicle angiogenesis.
Authors: Gutman G, Barak V, Maslovitz S, Amit A, Lessing JB, Geva E
Fertil. Steril., 2008-03-17;89(4):922-6.
Species: Human
Sample Types: Serum

Hypoxia-induced epithelial VEGF-C/VEGFR-3 upregulation in carcinoma cell lines.
Authors: Simiantonaki N, Jayasinghe C, Michel-Schmidt R, Peters K, Hermanns MI, Kirkpatrick CJ
Int. J. Oncol., 2008-03-01;32(3):585-92.
Species: Human
Sample Types: Cell Culture Supernates

Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function.
Authors: Marcondes AM, Mhyre AJ, Stirewalt DL, Kim SH, Dinarello CA, Deeg HJ
Proc. Natl. Acad. Sci. U.S.A., 2008-02-19;105(8):2865-70.
Species: Human
Sample Types: Bone Marrow Fluid

Tissue inhibitor of metalloproteinase-3 via oncolytic herpesvirus inhibits tumor growth and vascular progenitors.
Authors: Mahller YY, Vaikunth SS, Ripberger MC, Baird WH, Saeki Y, Cancelas JA, Crombleholme TM, Cripe TP
Cancer Res., 2008-02-15;68(4):1170-9.
Species: Human
Sample Types: Plasma

Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma?
Authors: Ganter MT, Cohen MJ, Brohi K, Chesebro BB, Staudenmayer KL, Rahn P, Christiaans SC, Bir ND, Pittet JF
Ann. Surg., 2008-02-01;247(2):320-6.
Species: Human
Sample Types: Plasma

Vascular endothelial growth factor-mediated decrease in plasma soluble vascular endothelial growth factor receptor-2 levels as a surrogate biomarker for tumor growth.
Authors: Ebos JM, Lee CR, Bogdanovic E, Alami J, Van Slyke P, Francia G, Xu P, Mutsaers AJ, Dumont DJ, Kerbel RS
Cancer Res., 2008-01-15;68(2):521-9.
Species: Human
Sample Types: Cell Culture Supernates

Relationship of soluble CD40 ligand to vascular endothelial growth factor, angiopoietins, and tissue factor in atrial fibrillation: a link among platelet activation, angiogenesis, and thrombosis?
Authors: Choudhury A, Freestone B, Patel J, Lip GY
Chest, 2007-12-01;132(6):1913-9.
Species: Human
Sample Types: Plasma

The levels of steroid hormones and cytokines in individual follicles are not associated with the fertilization outcome after intracytoplasmic sperm injection.
Authors: Asimakopoulos B, Abu-Hassan D, Metzen E, Al-Hasani S, Diedrich K, Nikolettos N
Fertil. Steril., 2007-11-05;90(1):60-4.
Species: Human
Sample Types: Follicular Fluid

Plasma angiogenin levels in acute coronary syndromes: implications for prognosis.
Authors: Tello-Montoliu A, Marin F, Patel J, Roldan V, Mainar L, Vicente V, Sogorb F, Lip GY
Eur. Heart J., 2007-11-02;28(24):3006-11.
Species: Human
Sample Types: Plasma

Vascular endothelial growth factor is up-regulated after status epilepticus and protects against seizure-induced neuronal loss in hippocampus.
Authors: Nicoletti JN, Shah SK, McCloskey DP, Goodman JH, Elkady A, Atassi H, Hylton D, Rudge JS, Scharfman HE, Croll SD
Neuroscience, 2007-10-26;151(1):232-41.
Species: Rat
Sample Types: Tissue Homogenates

Phase II trial of sunitinib in patients with metastatic colorectal cancer after failure of standard therapy.
Authors: Saltz LB, Rosen LS, Marshall JL, Belt RJ, Hurwitz HI, Eckhardt SG, Bergsland EK, Haller DG, Lockhart AC, Rocha Lima CM, Huang X, DePrimo SE, Chow-Maneval E, Chao RC, Lenz HJ
J. Clin. Oncol., 2007-10-20;25(30):4793-9.
Species: Human
Sample Types: Plasma

Tumor necrosis factor alpha as a new target for renal cell carcinoma: two sequential phase II trials of infliximab at standard and high dose.
Authors: Harrison ML, Obermueller E, Maisey NR, Hoare S, Edmonds K, Li NF, Chao D, Hall K, Lee C, Timotheadou E, Charles K, Ahern R, King DM, Eisen T, Corringham R, DeWitte M, Balkwill F, Gore M
J. Clin. Oncol., 2007-10-10;25(29):4542-9.
Species: Human
Sample Types: Plasma

Where is VEGF in the body? A meta-analysis of VEGF distribution in cancer.
Authors: Kut C, Mac Gabhann F, Popel AS
Br. J. Cancer, 2007-10-02;97(7):978-85.
Species: Human
Sample Types: Serum

Airway remodeling and lack of bronchodilator response in steroid-resistant asthma.
Authors: Goleva E, Hauk PJ, Boguniewicz J, Martin RJ, Leung DY
J. Allergy Clin. Immunol., 2007-09-27;120(5):1065-72.
Species: Human
Sample Types: BALF

Hypoxia-induced mediators of stem/progenitor cell trafficking are increased in children with hemangioma.
Authors: Kleinman ME, Greives MR, Churgin SS, Blechman KM, Chang EI, Ceradini DJ, Tepper OM, Gurtner GC
Arterioscler. Thromb. Vasc. Biol., 2007-09-13;27(12):2664-70.
Species: Human
Sample Types: Plasma

The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiogenesis.
Authors: Colla S, Tagliaferri S, Morandi F, Lunghi P, Donofrio G, Martorana D, Mancini C, Lazzaretti M, Mazzera L, Ravanetti L, Bonomini S, Ferrari L, Miranda C, Ladetto M, Neri TM, Neri A, Greco A, Mangoni M, Bonati A, Rizzoli V, Giuliani N
Blood, 2007-09-11;110(13):4464-75.
Species: Human
Sample Types: Plasma

Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia.
Authors: Lee CY, Tien HF, Hu CY, Chou WC, Lin LI
Br. J. Cancer, 2007-09-11;97(7):877-82.
Species: Human
Sample Types: Plasma

Tissue engineering for full-thickness burns: a dermal substitute from bench to bedside.
Authors: Kellouche S, Martin C, Korb G, Rezzonico R, Bouard D, Benbunan M, Dubertret L, Soler C, Legrand C, Dosquet C
Biochem. Biophys. Res. Commun., 2007-09-04;363(3):472-8.
Species: Human
Sample Types: Cell Culture Supernates

Vascular remodeling is a feature of asthma and nonasthmatic eosinophilic bronchitis.
Authors: Siddiqui S, Sutcliffe A, Shikotra A, Woodman L, Doe C, McKenna S, Wardlaw A, Bradding P, Pavord I, Brightling C
J. Allergy Clin. Immunol., 2007-07-05;120(4):813-9.
Species: Human
Sample Types: Sputum

Increased circulating endothelial progenitor cells in septic patients: correlation with survival.
Authors: Rafat N, Hanusch C, Brinkkoetter PT, Schulte J, Brade J, Zijlstra JG, van der Woude FJ, van Ackern K, Yard BA, Beck GCh
Crit. Care Med., 2007-07-01;35(7):1677-84.
Species: Human
Sample Types: Serum

Serum concentrations of angiogenic cytokines in Waldenstrom macroglobulinaemia: the ration of angiopoietin-1 to angiopoietin-2 and angiogenin correlate with disease severity.
Authors: Anagnostopoulos A, Eleftherakis-Papaiakovou V, Kastritis E, Tsionos K, Bamias A, Meletis J, Dimopoulos MA, Terpos E
Br. J. Haematol., 2007-06-01;137(6):560-8.
Species: Human
Sample Types: Serum

Phase I clinical and pharmacodynamic evaluation of oral CI-1033 in patients with refractory cancer.
Authors: Zinner RG, Nemunaitis J, Eiseman I, Shin HJ, Olson SC, Christensen J, Huang X, Lenehan PF, Donato NJ, Shin DM
Clin. Cancer Res., 2007-05-15;13(10):3006-14.
Species: Human
Sample Types: Plasma

Serum angiopoietin-2 as a clinical marker for lung cancer.
Authors: Park JH, Park KJ, Kim YS, Sheen SS, Lee KS, Lee HN, Oh YJ, Hwang SC
Chest, 2007-05-15;132(1):200-6.
Species: Human
Sample Types: Serum

Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor.
Authors: Norden-Zfoni A, Desai J, Manola J, Beaudry P, Force J, Maki R, Folkman J, Bello C, Baum C, DePrimo SE, Shalinsky DR, Demetri GD, Heymach JV
Clin. Cancer Res., 2007-05-01;13(9):2643-50.
Species: Human
Sample Types: Plasma

Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts.
Authors: Riccioni R, Diverio D, Mariani G, Buffolino S, Riti V, Saulle E, Petrucci E, Cedrone M, Lo-Coco F, Foa R, Peschle C, Testa U
Stem Cells, 2007-04-19;25(8):1862-71.
Species: Human
Sample Types: Cell Culture Supernates

Roles of angiopoietin-1 and angiopoietin-2 on airway microvascular permeability in asthmatic patients.
Authors: Kanazawa H, Nomura S, Asai K
Chest, 2007-04-01;131(4):1035-41.
Species: Human
Sample Types: Sputum

Expression and release of soluble HLA-E is an immunoregulatory feature of endothelial cell activation.
Authors: Coupel S, Moreau A, Hamidou M, Horejsi V, Soulillou JP, Charreau B
Blood, 2007-04-01;109(7):2806-14.
Species: Human
Sample Types: Serum

Mesenchymal stem cells support migration, extracellular matrix invasion, proliferation, and survival of endothelial cells in vitro.
Authors: Potapova IA, Gaudette GR, Brink PR, Robinson RB, Rosen MR, Cohen IS, Doronin SV
Stem Cells, 2007-03-29;25(7):1761-8.
Species: Human
Sample Types: Cell Culture Supernates

Evaluation of a xenogeneic VEGF vaccine in dogs with soft tissue sarcoma.
Authors: Kamstock D, Elmslie R, Thamm D
Cancer Immunol. Immunother., 2007-02-14;56(8):1299-309.
Species: Canine
Sample Types: Plasma

Significant decrease in angiopoietin-1 and angiopoietin-2 after radical prostatectomy in prostate cancer patients.
Authors: Caine GJ, Ryan P, Lip GY, Blann AD
Cancer Lett., 2007-01-19;251(2):296-301.
Species: Human
Sample Types: Plasma

Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth.
Authors: Laakkonen P, Waltari M, Holopainen T, Takahashi T, Pytowski B, Steiner P, Hicklin D, Persaud K, Tonra JR, Witte L, Alitalo K
Cancer Res., 2007-01-15;67(2):593-9.
Species: Human
Sample Types: Cell Culture Supernates

Angiogenic growth factors in maternal and fetal serum in pregnancies complicated by intrauterine growth restriction.
Authors: Wallner W, Sengenberger R, Strick R, Strissel PL, Meurer B, Beckmann MW, Schlembach D
Clin. Sci., 2007-01-01;112(1):51-7.
Species: Human
Sample Types: Serum

Platelet-derived growth factor-BB controls epithelial tumor phenotype by differential growth factor regulation in stromal cells.
Authors: Lederle W, Stark HJ, Skobe M, Fusenig NE, Mueller MM
Am. J. Pathol., 2006-11-01;169(5):1767-83.
Species: Human
Sample Types: Cell Culture Supernates

Oncostatin M induces angiogenesis and cartilage degradation in rheumatoid arthritis synovial tissue and human cartilage cocultures.
Authors: Fearon U, Mullan R, Markham T, Connolly M, Sullivan S, Poole AR, FitzGerald O, Bresnihan B, Veale DJ
Arthritis Rheum., 2006-10-01;54(10):3152-62.
Species: Human
Sample Types: Cell Culture Supernates

Early vascular and neuronal changes in a VEGF transgenic mouse model of retinal neovascularization.
Authors: van Eeden PE, Tee LB, Lukehurst S, Lai CM, Rakoczy EP, Beazley LD, Dunlop SA
Invest. Ophthalmol. Vis. Sci., 2006-10-01;47(10):4638-45.
Species: Human
Sample Types: Aqueous Humor

Endostatin variations in childhood acute lymphoblastic leukaemia--comparison with basic fibroblast growth factor and vascular endothelial growth factor.
Authors: Schneider P, Vasse M, Corbiere C, Legrand E, Marie-Cardine A, Boquet C, Cazin L, Vannier JP
Leuk. Res., 2006-09-29;31(5):629-38.
Species: Human
Sample Types: Plasma

A phase I biological and pharmacologic study of the heparanase inhibitor PI-88 in patients with advanced solid tumors.
Authors: Basche M, Gustafson DL, Holden SN, O'Bryant CL, Gore L, Witta S, Schultz MK, Morrow M, Levin A, Creese BR, Kangas M, Roberts K, Nguyen T, Davis K, Addison RS, Moore JC, Eckhardt SG
Clin. Cancer Res., 2006-09-15;12(18):5471-80.
Species: Human
Sample Types: Plasma

Humoral and cellular factors responsible for coronary collateral formation.
Authors: Sherman JA, Hall A, Malenka DJ, De Muinck ED, Simons M
Am. J. Cardiol., 2006-08-31;98(9):1194-7.
Species: Human
Sample Types: Plasma

Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer.
Authors: Caine GJ, Stonelake PS, Lip GY, Blann AD
Cancer Lett., 2006-08-07;248(1):131-6.
Species: Human
Sample Types: Plasma

Phase II study of recombinant human endostatin in patients with advanced neuroendocrine tumors.
Authors: Kulke MH, Bergsland EK, Ryan DP, Enzinger PC, Lynch TJ, Zhu AX, Meyerhardt JA, Heymach JV, Fogler WE, Sidor C, Michelini A, Kinsella K, Venook AP, Fuchs CS
J. Clin. Oncol., 2006-08-01;24(22):3555-61.
Species: Human
Sample Types: Urine

Dendritic cells can turn CD4+ T lymphocytes into vascular endothelial growth factor-carrying cells by intercellular neuropilin-1 transfer.
Authors: Bourbie-Vaudaine S, Blanchard N, Hivroz C, Romeo PH
J. Immunol., 2006-08-01;177(3):1460-9.
Species: Human
Sample Types: Cell Culture Supernates

Quantitative assessment of growth factors in reaming aspirate, iliac crest, and platelet preparation.
Authors: Herrmann S, Green J, Weber T, Scharfenberger A
Bone, 2006-07-25;39(5):1156-63.
Species: Human
Sample Types: Tissue Homogenates

Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice.
Authors: Rofstad EK, Mathiesen B, Kindem K, Galappathi K
Cancer Res., 2006-07-01;66(13):6699-707.
Species: Human
Sample Types: Cell Culture Supernates

Erythropoietin enhances neovascularization of ischemic myocardium and improves left ventricular dysfunction after myocardial infarction in dogs.
Authors: Hirata A, Minamino T, Asanuma H, Fujita M, Wakeno M, Myoishi M, Tsukamoto O, Okada K, Koyama H, Komamura K, Takashima S, Shinozaki Y, Mori H, Shiraga M, Kitakaze M, Hori M
J. Am. Coll. Cardiol., 2006-06-21;48(1):176-84.
Species: Canine
Sample Types: Plasma

Thiol regulation of vascular endothelial growth factor-A and its receptors in human retinal pigment epithelial cells.
Authors: Sreekumar PG, Kannan R, de Silva AT, Burton R, Ryan SJ, Hinton DR
Biochem. Biophys. Res. Commun., 2006-06-12;346(4):1200-6.
Species: Human
Sample Types: Cell Culture Supernates

Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells.
Authors: Moreno MJ, Ball M, Andrade MF, McDermid A, Stanimirovic DB
Glia, 2006-06-01;53(8):845-57.
Species: Human
Sample Types: Cell Culture Supernates

Effects of simvastatin on angiogenic growth factors released at the site of microvascular injury.
Authors: Undas A, Celinska-Lowenhoff M, Stepien E, Nizankowski R, Tracz W, Szczeklik A
Thromb. Haemost., 2006-06-01;95(6):1045-7.
Species: Human
Sample Types: Plasma

Serum levels of syndecan-1 in B-cell chronic lymphocytic leukemia: correlation with the extent of angiogenesis and disease-progression risk in early disease.
Authors: Molica S, Vitelli G, Mirabelli R, Digiesu G, Giannarelli D, Cuneo A, Ribatti D, Vacca A
Leuk. Lymphoma, 2006-06-01;47(6):1034-40.
Species: Human
Sample Types: Serum

Over-expression of p53 mutants in LNCaP cells alters tumor growth and angiogenesis in vivo.
Authors: Perryman LA, Blair JM, Kingsley EA, Szymanska B, Ow KT, Wen VW, MacKenzie KL, Vermeulen PB, Jackson P, Russell PJ
Biochem. Biophys. Res. Commun., 2006-05-11;345(3):1207-14.
Species: Human
Sample Types: Cell Culture Supernates

Vascular endothelial growth factor modulates matrix metalloproteinase-9 expression in asthma.
Authors: Lee KS, Min KH, Kim SR, Park SJ, Park HS, Jin GY, Lee YC
Am. J. Respir. Crit. Care Med., 2006-04-27;174(2):161-70.
Species: Human
Sample Types: BALF

Celecoxib up-regulates the expression of the zeta chain of T cell receptor complex in tumor-infiltrating lymphocytes in human cervical cancer.
Authors: Ferrandina G, Ranelletti FO, Legge F, Salutari V, Martinelli E, Fattorossi A, Lorusso D, Zannoni G, Vellone V, Paglia A, Scambia G
Clin. Cancer Res., 2006-04-01;12(7):2055-60.
Species: Human
Sample Types: Serum

The potential of adiponectin in driving arthritis.
Authors: Ehling A, Schaffler A, Herfarth H, Tarner IH, Anders S, Distler O, Paul G, Distler J, Gay S, Scholmerich J, Neumann E, Muller-Ladner U
J. Immunol., 2006-04-01;176(7):4468-78.
Species: Human
Sample Types: Cell Culture Supernates

Cardiac expression of placental growth factor predicts the improvement of chronic phase left ventricular function in patients with acute myocardial infarction.
Authors: Iwama H, Uemura S, Naya N, Imagawa K, Takemoto Y, Asai O, Onoue K, Okayama S, Somekawa S, Kida Y, Takeda Y, Nakatani K, Takaoka M, Kawata H, Horii M, Nakajima T, Doi N, Saito Y
J. Am. Coll. Cardiol., 2006-03-27;47(8):1559-67.
Species: Human
Sample Types: Plasma

Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities.
Authors: Pang L, Nie M, Corbett L, Sutcliffe A, Knox AJ
J. Immunol., 2006-03-15;176(6):3788-95.
Species: Human
Sample Types: Cell Culture Supernates

Changes in the circulating plasma levels of VEGF and VEGF-D after adjuvant chemotherapy in patients with breast cancer and 1 to 3 positive lymph nodes.
Authors: Kummel S, Eggemann H, Luftner D, Thomas A, Jeschke S, Zerfel N, Heilmann V, Emons G, Zeiser T, Ulm K, Kobl M, Korlach S, Schmid P, Sehouli J, Elling D, Blohmer JU
Anticancer Res., 2006-03-01;26(2):1719-26.
Species: Human
Sample Types: Plasma

Circulating angiogenic factors in preeclampsia, gestational proteinuria, and preeclampsia superimposed on chronic glomerulonephritis.
Authors: Masuyama H, Suwaki N, Nakatsukasa H, Masumoto A, Tateishi Y, Hiramatrsu Y
Am. J. Obstet. Gynecol., 2006-02-01;194(2):551-6.
Species: Human
Sample Types: Serum

Relation of various plasma growth factor levels in patients with stable angina pectoris and total occlusion of a coronary artery to the degree of coronary collaterals.
Authors: Briguori C, Testa U, Colombo A, Petrucci E, Condorelli G, Airoldi F, Peschle C, Condorelli G
Am. J. Cardiol., 2005-12-20;97(4):472-6.
Species: Human
Sample Types: Serum

IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis.
Authors: Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H
J. Immunol., 2005-11-01;175(9):6177-89.
Species: Human
Sample Types: Cell Culture Supernates

Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis.
Authors: Iversen PO, Wiig H
Clin. Cancer Res., 2005-10-01;11(19):6793-9.
Species: Human
Sample Types: Bone Marrow Fluid

Evaluating hypoxia-inducible factor-1alpha as a cancer therapeutic target via inducible RNA interference in vivo.
Authors: Li L, Lin X, Staver M, Shoemaker A, Semizarov D, Fesik SW, Shen Y
Cancer Res., 2005-08-15;65(16):7249-58.
Species: Human
Sample Types: Cell Culture Supernates

Platelet-derived growth factor-AA is an essential and autocrine regulator of vascular endothelial growth factor expression in non-small cell lung carcinomas.
Authors: Shikada Y, Yonemitsu Y, Koga T, Onimaru M, Nakano T, Okano S, Sata S, Nakagawa K, Yoshino I, Maehara Y, Sueishi K
Cancer Res., 2005-08-15;65(16):7241-8.
Species: Human
Sample Types: Cell Culture Supernates

Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours.
Authors: Mross K, Drevs J, Muller M, Medinger M, Marme D, Hennig J, Morgan B, Lebwohl D, Masson E, Ho YY, Gunther C, Laurent D, Unger C
Eur. J. Cancer, 2005-06-01;41(9):1291-9.
Species: Human
Sample Types: Plasma

Genetic and clinical factors influence the baseline permeability of the peritoneal membrane.
Authors: Gillerot G, Goffin E, Michel C, Evenepoel P, Biesen WV, Tintillier M, Stenvinkel P, Heimburger O, Lindholm B, Nordfors L, Robert A, Devuyst O
Kidney Int., 2005-06-01;67(6):2477-87.
Species: Human
Sample Types: Plasma

Vascular endothelial growth factor in pleural effusions of different origin.
Authors: Sack U, Hoffmann M, Zhao XJ, Chan KS, Hui DS, Gosse H, Engelmann L, Schauer J, Emmrich F, Hoheisel G
Eur. Respir. J., 2005-04-01;25(4):600-4.
Species: Human
Sample Types: Serum

Vitreous levels of angiopoietin 2 and vascular endothelial growth factor in patients with proliferative diabetic retinopathy.
Authors: Watanabe D, Suzuma K, Suzuma I, Ohashi H, Ojima T, Takagi H
Am. J. Ophthalmol., 2005-03-01;139(3):476-81.
Species: Human
Sample Types: Vitreous Humor

Antibody neutralization of vascular endothelial growth factor (VEGF) fails to attenuate vascular permeability and brain edema in experimental pneumococcal meningitis.
Authors: van der Flier M, Coenjaerts FE, Mwinzi PN, Rijkers E, Ruyken M, Scharringa J, Kimpen JL, Hoepelman AI, Geelen SP
J. Neuroimmunol., 2005-03-01;160(1):170-7.
Species: Rabbit
Sample Types: CSF

Urinary angiogenic factors cluster hypertensive disorders and identify women with severe preeclampsia.
Authors: Buhimschi CS, Norwitz ER, Funai E, Richman S, Guller S, Lockwood CJ, Buhimschi IA
Am. J. Obstet. Gynecol., 2005-03-01;192(3):734-41.
Species: Human
Sample Types: Urine

A potential role for vascular endothelial growth factor-D as an autocrine growth factor for human breast carcinoma cells.
Authors: Akahane M, Akahane T, Shah A, Okajima E, Thorgeirsson UP
Anticancer Res., 2005-03-01;25(2):701-7.
Species: Human
Sample Types: Cell Culture Supernates

Urinary placental growth factor and risk of preeclampsia.
Authors: Levine RJ, Thadhani R, Qian C, Lam C, Lim KH, Yu KF, Blink AL, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA
JAMA, 2005-01-05;293(1):77-85.
Species: Human
Sample Types: Urine

Hyperbaric oxygen and ovarian follicular stimulation for in vitro fertilization: a pilot study.
Authors: Van Voorhis BJ, Greensmith JE, Dokras A, Sparks AE, Simmons ST, Syrop CH
Fertil. Steril., 2005-01-01;83(1):226-8.
Species: Human
Sample Types: Follicular Fluid

A potential pro-angiogenic cell therapy with human placenta-derived mesenchymal cells.
Authors: Nishishita T, Ouchi K, Zhang X, Inoue M, Inazawa T, Yoshiura K, Kuwabara K, Nakaoka T, Watanabe N, Igura K, Takahashi TA, Yamashita N
Biochem. Biophys. Res. Commun., 2004-12-03;325(1):24-31.
Species: Human
Sample Types: Cell Lysates

Vitreous levels of vascular endothelial growth factor and stromal-derived factor 1 in patients with diabetic retinopathy and cystoid macular edema before and after intraocular injection of triamcinolone.
Authors: Brooks HL, Caballero S, Newell CK, Steinmetz RL, Watson D, Segal MS, Harrison JK, Scott EW, Grant MB
Arch. Ophthalmol., 2004-12-01;122(12):1801-7.
Species: Human
Sample Types: Vitreous Humor

Bi-directional cell contact-dependent regulation of gene expression between endothelial cells and osteoblasts in a three-dimensional spheroidal coculture model.
Authors: Stahl A, Wenger A, Weber H, Stark GB, Augustin HG, Finkenzeller G
Biochem. Biophys. Res. Commun., 2004-09-17;322(2):684-92.
Species: Human
Sample Types: Cell Culture Supernates

Estrogen enhances angiogenesis through a pathway involving platelet-activating factor-mediated nuclear factor-kappaB activation.
Authors: Seo KH, Lee HS, Jung B, Ko HM, Choi JH, Park SJ, Choi IH, Lee HK, Im SY
Cancer Res., 2004-09-15;64(18):6482-8.
Species: Human
Sample Types: Cell Culture Supernates

The histone deacetylase inhibitor NVP-LAQ824 inhibits angiogenesis and has a greater antitumor effect in combination with the vascular endothelial growth factor receptor tyrosine kinase inhibitor PTK787/ZK222584.
Authors: Qian DZ, Wang X, Kachhap SK, Kato Y, Wei Y, Zhang L, Atadja P, Pili R
Cancer Res., 2004-09-15;64(18):6626-34.
Species: Human
Sample Types: Cell Culture Supernates

PEDF derived from glial Muller cells: a possible regulator of retinal angiogenesis.
Authors: Eichler W, Yafai Y, Keller T, Wiedemann P, Reichenbach A
Exp. Cell Res., 2004-09-10;299(1):68-78.
Species: Guinea Pig
Sample Types: Cell Culture Supernates

Vascular endothelial growth factor (VEGF) levels as a tool to discriminate between malignant and nonmalignant ascites.
Authors: Nascimento I, Schaer R, Lemaire D, Freire S, Paule B, Carvalho S, Meyer R, Schaer-Barbosa H
APMIS, 2004-09-01;112(9):585-7.
Species: Human
Sample Types: Ascites Fluid

Cerebrospinal fluid vascular endothelial growth factor in patients with amyotrophic lateral sclerosis.
Authors: Ilzecka J
Clin Neurol Neurosurg, 2004-09-01;106(4):289-93.
Species: Human
Sample Types: CSF

Follicular blood flow is a better predictor of the outcome of in vitro fertilization-embryo transfer than follicular fluid vascular endothelial growth factor and nitric oxide concentrations.
Authors: Kim KH, Oh DS, Jeong JH, Shin BS, Joo BS, Lee KS
Fertil. Steril., 2004-09-01;82(3):586-92.
Species: Human
Sample Types: Follicular Fluid

Follicular fluid concentrations of vascular endothelial growth factor, inhibin A and inhibin B in IVF cycles: are they markers for ovarian response and pregnancy outcome?
Authors: Ocal P, Aydin S, Cepni I, Idil S, Idil M, Uzun H, Benian A
Eur. J. Obstet. Gynecol. Reprod. Biol., 2004-08-10;115(2):194-9.
Species: Human
Sample Types: Follicular Fluid

High altitude training of dogs results in elevated erythropoietin and endothelin-1 serum levels.
Authors: Glaus TM, Grenacher B, Koch D, Reiner B, Gassmann M
Comp. Biochem. Physiol., Part A Mol. Integr. Physiol., 2004-07-01;138(3):355-61.
Species: Canine
Sample Types: Serum

Antioxidant intervention prevents renal neovascularization in hypercholesterolemic pigs.
Authors: Chade AR, Bentley MD, Zhu X, Rodriguez-Porcel M, Niemeyer S, Amores-Arriaga B, Napoli C, Ritman EL, Lerman A, Lerman LO
J. Am. Soc. Nephrol., 2004-07-01;15(7):1816-25.
Species: Porcine
Sample Types: Tissue Homogenates

Amniotic levels of nitric oxide and vascular endothelial growth factor in pregnancy with subsequent intrauterine fetal death.
Authors: Tranquilli AL, Giannubilo SR, Bezzeccheri V, Ciavattini A, Scagnoli C, Mazzanti L
Eur. J. Obstet. Gynecol. Reprod. Biol., 2004-06-15;114(2):162-5.
Species: Human
Sample Types: Amniotic Fluid

Urine vascular endothelial growth factor-A is not a useful marker for endometriosis.
Authors: Potlog-Nahari C, Stratton P, Winkel C, Widra E, Sinaii N, Connors S, Nieman LK
Fertil. Steril., 2004-06-01;81(6):1507-12.
Species: Human
Sample Types: Urine

Plasma and urinary vascular endothelial growth factor and diabetic nephropathy in Type 2 diabetes mellitus.
Authors: Kim NH, Kim KB, Kim DL, Kim SG, Choi KM, Baik SH, Choi DS, Kang YS, Han SY, Han KH, Ji YH, Cha DR
Diabet. Med., 2004-06-01;21(6):545-51.
Species: Human
Sample Types: Plasma

Hypoxia activates matrix metalloproteinase expression and the VEGF system in monkey choroid-retinal endothelial cells: Involvement of cytosolic phospholipase A2 activity.
Authors: Ottino P, Finley J, Rojo E, Ottlecz A, Lambrou GN, Bazan HE, Bazan NG
Mol. Vis., 2004-05-17;10(0):341-50.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Cell Culture Supernates

Effects of pranlukast administration on vascular endothelial growth factor levels in asthmatic patients.
Authors: Kanazawa H, Yoshikawa T, Hirata K, Yoshikawa J
Chest, 2004-05-01;125(5):1700-5.
Species: Human
Sample Types: Saliva

Reduced pericardial levels of endostatin correlate with collateral development in patients with ischemic heart disease.
Authors: Panchal VR, Rehman J, Nguyen AT, Brown JW, Turrentine MW, Mahomed Y, March KL
J. Am. Coll. Cardiol., 2004-04-21;43(8):1383-7.
Species: Human
Sample Types: Pericardial Fluid

Elevated erythropoietin in vitreous with ischemic retinal diseases.
Authors: Inomata Y, Hirata A, Takahashi E, Kawaji T, Fukushima M, Tanihara H
Neuroreport, 2004-04-09;15(5):877-9.
Species: Human
Sample Types: Serum

Clinicopathologic correlation of progressive fibrovascular proliferation associated with occult choroidal neovascularization in age-related macular degeneration.
Authors: Csaky K, Baffi J, Chan CC, Byrnes GA
Arch. Ophthalmol., 2004-04-01;122(4):650-2.
Species: Human
Sample Types: Subretinal Fluid

Vascular endothelial growth factor is increased in cerebrospinal fluid after traumatic brain injury in infants and children.
Authors: Shore PM, Jackson EK, Wisniewski SR, Clark RS, Adelson PD, Kochanek PM
Neurosurgery, 2004-03-01;54(3):605-11; discu.
Species: Human
Sample Types: CSF

Vascular endothelial growth factor (VEGF) concentration in sera and tumor effusions from patients with ovarian carcinoma.
Authors: Harlozinska A, Sedlaczek P, Kulpa J, Grybos M, Wojcik E, Van Dalen A, Einarsson R
Anticancer Res., 2004-03-01;24(2):1149-57.
Species: Human
Sample Types: Serum

Circulating angiogenic factors and the risk of preeclampsia.
Authors: Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, Yu KF, Schisterman EF, Thadhani R, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA
N. Engl. J. Med., 2004-02-05;350(7):672-83.
Species: Human
Sample Types: Serum

Neoadjuvant therapy and biliary decompression lower biliary and pancreatic juice vascular endothelial growth factor levels in patients with periampullary adenocarcinoma.
Authors: Berger AC, Watson JC, Ross EA, Zalatoris A, Hoffman JP
Am Surg, 2004-02-01;70(2):169-73; discu.
Species: Human
Sample Types: Plasma

Conduction performance of collateral vessels induced by vascular endothelial growth factor or basic fibroblast growth factor.
Authors: Kondoh K, Koyama H, Miyata T, Takato T, Hamada H, Shigematsu H
Cardiovasc. Res., 2004-01-01;61(1):132-42.
Species: Rabbit
Sample Types: Cell Culture Supernates

Hepatocyte growth factor in the vitreous fluid of patients with proliferative diabetic retinopathy: its relationship with vascular endothelial growth factor and retinopathy activity.
Authors: Simo R, Lecube A, Garcia-Arumi J, Carrasco E, Hernandez C
Diabetes Care, 2004-01-01;27(1):287-8.
Species: Human
Sample Types: Vitreous Humor

Expansion of human SCID-repopulating cells under hypoxic conditions.
Authors: Danet GH, Pan Y, Luongo JL, Bonnet DA, Simon MC
J. Clin. Invest., 2003-07-01;112(1):126-35.
Species: Human
Sample Types: Cell Culture Supernates

Have urinary levels of the angiogenic factors, basic fibroblast growth factor and vascular endothelial growth factor, a prognostic value in childhood acute lymphoblastic leukaemia?
Authors: Schneider P, Vasse M, Legrand E, Callat MP, Vannier JP
Br. J. Haematol., 2003-07-01;122(1):163-4.
Species: Human
Sample Types: Urine

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia.
Authors: Maynard SE, Min JY, Merchan J, Lim KH, Mondal S, Stillman IE, Epstein FH, Karumanchi SA
J. Clin. Invest., 2003-03-01;111(5):649-58.
Species: Human
Sample Types: Serum

Correlation of increased vascular endothelial growth factor with neovascularization and permeability in ischemic central vein occlusion.
Authors: Boyd SR, Zachary I, Chakravarthy U, Allen GJ, Wisdom GB, Cree IA, Martin JF, Hykin PG
Arch. Ophthalmol., 2002-12-01;120(12):1644-50.
Species: Human
Sample Types: Plasma

Flaxseed inhibits metastasis and decreases extracellular vascular endothelial growth factor in human breast cancer xenografts.
Authors: Dabrosin C, Chen J, Wang L, Thompson LU
Cancer Lett., 2002-11-08;185(1):31-7.
Species: Human
Sample Types: Tumor Interstitial Fluid

Intraperitoneal bispecific antibody (HEA125xOKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma.
Authors: Marme A, Strauss G, Bastert G, Grischke EM, Moldenhauer G
Int. J. Cancer, 2002-09-10;101(2):183-9.
Species: Human
Sample Types: Ascites Fluid

Unbalanced vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in diabetic retinopathy.
Authors: Ogata N, Nishikawa M, Nishimura T, Mitsuma Y, Matsumura M
Am. J. Ophthalmol., 2002-09-01;134(3):348-53.
Species: Human
Sample Types: Vitreous Humor

Ovariectomy increases mitogens and platelet-induced proliferation of arterial smooth muscle.
Authors: Bracamonte MP, Rud KS, Owen WG, Miller VM
Am. J. Physiol. Heart Circ. Physiol., 2002-09-01;283(3):H853-60.
Species: Porcine
Sample Types: Cell Lysates

Free insulin growth factor-I and vascular endothelial growth factor in the vitreous fluid of patients with proliferative diabetic retinopathy.
Authors: Simo R, Lecube A, Segura RM, Garcia Arumi J, Hernandez C
Am. J. Ophthalmol., 2002-09-01;134(3):376-82.
Species: Human
Sample Types: Vitreous Humor

Nitric oxide and vascular endothelial growth factor concentrations are increased but not related in vitreous fluid of patients with proliferative diabetic retinopathy.
Authors: Hernandez C, 2019, Lecube A, Segura RM, Sararols L, Simo R
eaav9040, 2002-08-01;19(8):655-60.
Species: Human
Sample Types: Vitreous Humor

Human chorionic gonadotropin-induced ovarian hyperstimulation syndrome is associated with up-regulation of vascular endothelial growth factor.
Authors: Wang TH, 14, Horng SG, Chang CL, Wu HM, Tsai YJ, Wang HS, Soong YK
The biggest risk factor for obesity and its associated comorbidities is a Western diet. This Western diet induces adipose tissue (AT) inflammation, which causes an AT dysfunction. Since AT is a vital, 2002-07-01;87(7):3300-8.
Species: Human
Sample Types: Serum

High basic fibroblast growth factor levels in nipple aspirate fluid are correlated with breast cancer.
Authors: Hsiung R, Zhu W, Klein G, Qin W, Rosenberg A, Park P, Rosato E, Sauter E
Cancer J, 2002-07-01;8(4):303-10.
Species: Human
Sample Types: Tissue Secretion

Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome.
Authors: Zhou Y, 2019, McMaster M, Woo K, Janatpour M, Perry J, Karpanen T, Alitalo K, Damsky C, Fisher SJ
2002-04-01;160(4):1405-23.
Species: Human
Sample Types: Cell Culture Supernates

Vascular endothelial growth factor concentrations in body cavity effusions in dogs.
Authors: Clifford CA, Hughes D, Beal MW, Henry CJ, Drobatz KJ, Sorenmo KU
J. Vet. Intern. Med., 2002-03-01;16(2):164-8.
Species: Canine
Sample Types: Complex Sample Type

VEGF-A, VEGF-C, and VEGF-D in colorectal cancer progression.
Authors: George ML, Tutton MG, Janssen F, Arnaout A, Abulafi AM, Eccles SA, Swift RI
Neoplasia, 2001-09-01;3(5):420-7.
Species: Human
Sample Types: Tissue Homogenates

Clinical factors related to the aqueous levels of vascular endothelial growth factor and hepatocyte growth factor in proliferative diabetic retinopathy.
Authors: Shinoda K, Ishida S, Kawashima S, Wakabayashi T, Uchita M, Matsuzaki T, Takayama M, Shinmura K, Yamada M
Curr. Eye Res., 2000-08-01;21(2):655-61.
Species: Human
Sample Types: Aqueous Humor

Angiogenic balance in human melanoma: expression of VEGF, bFGF, IL-8, PDGF and angiostatin in relation to vascular density of xenografts in vivo.
Authors: Westphal JR, Van't Hullenaar R, Peek R, Willems RW, Crickard K, Crickard U, Askaa J, Clemmensen I, Ruiter DJ, De Waal RM
Int. J. Cancer, 2000-06-15;86(6):768-76.
Species: Human
Sample Types: Cell Culture Supernates

Electromagnetic guidance for catheter-based transendocardial injection: a platform for intramyocardial angiogenesis therapy. Results in normal and ischemic porcine models.
Authors: Kornowski R, Leon MB, Fuchs S, Vodovotz Y, Flynn MA, Gordon DA, Pierre A, Kovesdi I, Keiser JA, Epstein SE
J. Am. Coll. Cardiol., 2000-03-15;35(4):1031-9.
Species: Porcine
Sample Types: Tissue Homogenates

Vascular endothelial growth factor (VEGF) and angiopoietin regulation by gonadotrophin and steroids in macaque granulosa cells during the peri-ovulatory interval.
Authors: Hazzard TM, 49529, Molskness TA, Chaffin CL, Stouffer RL
The therapeutic HIV Env C5/gp41 vaccine candidate Vacc-C5 induces specific T cell regulation in a phase I/II clinical study, 1999-12-01;5(12):1115-21.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Follicular Fluid

Growth factors and proinflammatory cytokines in the renal involvement of POEMS syndrome.
Authors: Soubrier M, Sauron C, Souweine B, Larroche C, Wechsler B, Guillevin L, Piette JC, Rousset H, Deteix P
Am. J. Kidney Dis., 1999-10-01;34(4):633-8.
Species: Human
Sample Types: Serum

Adenosine upregulates VEGF expression in cultured myocardial vascular smooth muscle cells.
Authors: Gu JW, Brady AL, Anand V, Moore MC, Kelly WC, Adair TH
Am. J. Physiol., 1999-08-01;277(2):H595-602.
Species: Canine
Sample Types: Cell Culture Supernates

Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I.
Authors: Akagi Y, Liu W, Zebrowski B, Xie K, Ellis LM
Cancer Res., 1998-09-01;58(17):4008-14.
Species: Human
Sample Types: Cell Lysates

Hypoxia-induced expression of VEGF is reversible in myocardial vascular smooth muscle cells.
Authors: Gu JW, Adair TH
Am. J. Physiol., 1997-08-01;273(2):H628-33.
Species: Canine
Sample Types: Cell Culture Supernates

FAQs

Does the Human VEGF Quantikine^® ELISA kit (Catalog # DVE00) detect mouse VEGF?
- No, the kit does not detect mouse VEGF. Specificity testing with recombinant mouse VEGF 120 and VEGF 164 showed no cross-reactivity. For the detection of mouse VEGF, please refer to the Mouse VEGF Quantikine^® ELISA kit (Catalog # MMV00).
Does the Human VEGF Quantikine^®ELISA kit (Catalog # DVE00) detect porcine samples?
- Our lab has not tested porcine samples in the kit, however many customers have published use of the kit with porcine samples. Links to these references can be found in the citations tab by selecting for Porcine in the Species filter.
Is the heterodimer VEGF₁₆₅/PlGF detected by DVE00?
- VEGF₁₆₅/PlGF is not detected by this kit. Recombinant human VEGF₁₆₅/PlGF was prepared at 50 ng/mL and assayed for cross-reactivity, with negative results.
Is there a protocol for using cell lysates with the Human VEGF Quantikine^® ELISA Kit (Catalog # DVE00)?
- R&D Systems does not have a validated cell lysate protocol available for this kit. However, many customers have published use of the kit with cell lysates. Links to these references can be found in the citations tab. Generally, the use of detergents in the lysis buffer should be avoided when preparing cell samples. A better option is to lyse the cells via freeze/thaw cycles or by sonication.
Does the Human VEGF Quantikine^® ELISA kit (Catalog # DVE00) detect human VEGF₁₂₁?
- Yes, the kit detects VEGF₁₂₁. In specificity testing, 100% cross-reactivity was observed with recombinant human VEGF₁₂₁.
How long can samples (cell cultures, serum, and plasma) be stored and still be stable for measuring VEGF using the DVE00 Human VEGF Quantikine^® ELISA Kit?
- R&D Systems does not evaluate sample stability. Variations in sample collection, processing, and storage may affect stability of samples. It is recommend to assay sample immediately after collection when possible, or aliquot into single use volumes and store samples frozen. Avoid repeat freeze-thaw cycles with the stored samples to avoid protein degradation.

View all ELISA FAQs

Reviews for Human VEGF Quantikine ELISA Kit

Average Rating: 4.9 (Based on 29 Reviews)

5 Star

86.21%

4 Star

13.79%

3 Star

2 Star

1 Star

Have you used Human VEGF Quantikine ELISA Kit?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by: