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JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
Potent, selective TrkA inhibitor
Inhibits NGF binding to p75NTR and TrkA
Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC
Inhibits NGF binding to p75NTR
Selective TrkB receptor agonist; neuroprotectant
Potent and selective pan-Trk inhibitor; peripherally restricted