HMG-CoA Reductase Inhibitors: Products
A transmembrane enzyme, 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMG-CoA reductase) catalyzes the rate limiting step in cholesterol biosynthesis - conversion of 3-hydroxy-3-methyl-glutaryl-CoA to mevalonic acid. It is bound to endoplasmic reticulum.
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