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Potent and selective ATM kinase inhibitor
Potent and selective DNA-PK inhibitor
Inhibitor of PI 3-kinase, mTOR and DNA-PK
Potent and selective inhibitor of Chk1 and Wee1
Selective DNA-PK inhibitor
Potent Src inhibitor; also inhibits FGFR1, PDGFRβ and Wee1
Potent and selective Mps1 kinase inhibitor
Cdk inhibitor; potently inhibits cdk9; also inhibits MK2
MRN-ATM pathway inhibitor
Dual DNA-PK and PI 3-K inhibitor
Selective Mps1 kinase inhibitor
Potent and selective BUB1 kinase inhibitor
Potent and selective Wee1 inhibitor