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Highly selective GSK-3 inhibitor; acts as Wnt activator
CHIR 99021 synthesized to cGMP guidelines
Potent and selective inhibitor of TGF-βRI
Potent inhibitor of MEK1/2
Histone deacetylase inhibitor
p53 inhibitor. Also aryl hydrocarbon receptor agonist
Retinoic acid analog; RAR agonist
Potent histone deacetylase inhibitor
Irreversible inhibitor of LSD1; also inhibits MAO
RepSox synthesized to Ancillary Material Grade
Non-nucleoside DNA methyltransferase inhibitor
DNA methyltransferase inhibitor
Highly potent and selective GSK-3 inhibitor
GSK-3β inhibitor; also inhibits cdks
Inhibitor of p53-mitochondrial binding
Oct3/4 inducer; induces expression of pluripotent-associated genes
Potent PDGFRα and PDGFRβ inhibitor; also inhibits c-Abl, Lck, c-Src and Fyn kinases
Sterile-filtered 10 mM solution of CHIR 99021 pre-dissolved in DMSO