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O4I2

Catalog #: 5664 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5664/10
5664/50
O4I2 | CAS No. 165682-93-9 | Additional Stem Cell Dedifferentiation Products
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Description: Oct3/4 inducer; induces expression of pluripotent-associated genes

Chemical Name: Ethyl 2-[(4-chlorophenyl)amino]-4-thiazolecarboxylate

Purity: ≥98%

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Biological Activity

O4I2 is an Oct3/4 inducer; promotes Oct3/4 expression and stabilizes the Oct3/4 protein in HEK293 cells. Induces expression of pluripotent-associated genes Lin28, Sox2 and Nanog, and suppresses Rex1. Induces 15-fold increase in Oct3/4 expression in human primary fibroblasts.

Technical Data

M.Wt:
282.75
Formula:
C12H11ClN2O2S
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
165682-93-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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