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Cell-permeable, irreversible caspase inhibitor
E2 ubiquitin (Ub) conjugating enzymes inhibitor
Potent NLRP3 inflammasome inhibitor; inhibits IL-1β production
Caspase-1 and NLRP3 inflammasome inhibitor
Irreversible NLRP3 inhibitor
NLRP3 inhibitor; active in vivo
Potent NLRP3 inflammasome inhibitor
NLRP3 inflammasome inhibitor
Suppresses ROS-induced activation of the NLRP3 inflammasome; antimalarial
NLRP3 inflammasome inhibitor; disrupts inflammasome formation
NLRP3 inflammasome inhibitor
Potent NLRP3 inflammasome inhibitor