Home / Inflammasomes Inhibitors / INF 39

INF 39

Catalog #: 6341 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6341/10
INF 39 | CAS No. 866028-26-4 | Inflammasomes Inhibitors
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Description: Irreversible NLRP3 inhibitor

Chemical Name: Ethyl 2-(2-chlorobenzyl)acrylate

Purity: ≥98%

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Biological Activity

INF 39 is an irreversible NLRP3 inhibitor (exhibits 52% inhibition of NLRP3 ATPase at 100 μM). Inhibits IL-1β release, caspase activation and pyroptosis in THP-1 cells. Reduces inflammation in a rat colitis model. Exhibits low cytotoxicity.

Technical Data

M.Wt:
224.68
Formula:
C12H13ClO2
Solubility:
Soluble in DMSO (supplied pre-dissolved in DMSO, 10mg/ml)
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
866028-26-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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