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GAPDH inhibitor; neuroprotective
Succinate dehydrogenase inhibitor
Inosine monophosphatase dehydrogenase (IMPDH) inhibitor
Inosine monophosphate dehydrogenase (IMPDH) inhibitor
Inosine monophosphatase dehydrogenase (IMPDH) inhibitor
High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation
Malate dehydrogenase-2 (MDH2) inhibitor; also inhibits HIF-1α
Negative allosteric modulator of 3-phosphoglycerate dehydrogenase (PHGDH)
Negative allosteric modulator of 3-Phosphoglycerate dehydrogenase (PHGDH)
Potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1)
Potent, reversible glucose-6-phosphate dehydrogenase (G6PD) inhibitor
Potent inhibitor of mutant isocitrate dehydrogenase (mIDH1)
Potent and selective hydroxysteroid 17β dehydrogenase 13 (HSD17B13) inhibitor