Mouse Noggin Biotinylated Antibody

Catalog #: BAF719 Datasheet / COA / SDS

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BAF719

All Noggin Antibodies

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Mouse Noggin Biotinylated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Noggin in Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Noggin
Leu20-Cys232
Accession # P97466

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse Noggin (Catalog # 1967-NG)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Noggin

Noggin is a 232 amino acid (aa), ~31 kDa homodimer-forming glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Noggin is expressed in defined areas during development and in the adult central nervous system and peripheral tissues such as lung, skeletal muscle, and skin. It is important for neural tube, somite and cardiomyocyte growth and patterning, and for limiting chondrocyte growth. Noggin is secreted but probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Mature human, mouse, and rat Noggin share 99% aa sequence identity.

Entrez Gene IDs

9241 (Human); 18121 (Mouse)

Alternate Names

NOG; Noggin; SYM1; symphalangism 1 (proximal); synostoses (multiple) syndrome 1; SYNS1; SYNS1A