SCGF/CLEC11a: Products

Stem Cell Growth Factor Beta (SCGF) is a secreted sulfated glycoprotein that belongs to the C-type lectin superfamily and is expressed primarily in hematopoietic tissues. It functions as a growth factor for primitive hematopoietic progenitor cells. SCGF-beta is a truncated variant of SCGF that has a 78 amino acid residue deletion and lacks a functional calcium-dependent carbohydrate-recognition domain. The amino acid sequence of human SCGF is 85% identical to mouse and rat SCGF.