OCILRP2/CLEC2i: Products

OCILRP2 (Osteoclast Inhibitory Lectin Related Protein 2), also known as CLRG (C-type lectin related g) and CLEC2i (C-type lectin domain family 2, member i), is a type II transmembrane receptor. OCILRP2 is expressed on osteoclasts, chondrocytes, and lymphoid cell types. It is a ligand for NKrp1f (KLRB1f), another NK (natural killer) cell receptor. OCILRP2 inhibits osteoclast formation and can affect NK cell functions. The extracellular domain of mouse OCILRP2 shares 79% and 74% amino acid sequence identity with that of mouse OCILRP1 and OCIL, respectively.