Mouse Vitronectin Antibody Summary
Asp20-Lys478
Accession # AAH12690
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Vitronectin
Vitronectin is a 71 kDa secreted glycoprotein produced by the liver and tumor cells. In blood, Vitronectin is called serum spreading factor. In the extracellular matrix, its function is determined by binding partners such as PAI-1, complement factors, integrins (notably alpha v beta 3) and thrombin. The 459 aa mature mouse Vitronectin shows 74% amino acid identity with human Vitronectin and contains somatomedin B-like and hemopexin-like domains, an RGD motif, a basic heparin-binding domain and sulfated tyrosines. Unbound Vitronectin is a monomer that may be cleaved to form a dimer of 65 kDa and 10 kDa components.
Product Datasheets
Citations for Mouse Vitronectin Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Proteomics reveals Rictor as a noncanonical TGF-beta signaling target during aneurysm progression in Marfan mice
Authors: Sarah J. Parker, Aleksandr Stotland, Elena MacFarlane, Nicole Wilson, Amanda Orosco, Vidya Venkatraman et al.
American Journal of Physiology-Heart and Circulatory Physiology
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Plasminogen activator inhibitor‐1 regulates the vascular expression of vitronectin
Authors: M. Luo, Y. Ji, Y. Luo, R. Li, W. P. Fay, J. Wu
Journal of Thrombosis and Haemostasis
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