Mouse VE-Statin Isoform 1 Biotinylated Antibody

Catalog #: BAF3089 Datasheet / COA / SDS

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BAF3089

All VE-Statin Antibodies

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Mouse VE-Statin Isoform 1 Biotinylated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse VE‑Statin Isoform 1 in Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human VE‑Statin is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant mouse VE‑Statin Isoform 1
Thr21-Leu275
Accession # Q9QXT5

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse VE-Statin Isoform 1

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: VE-Statin

VE-Statin, also known as epidermal growth factor-like domain 7 (EGFL7), is a secreted endothelial-specific protein that is a marker for progenitor, embryonic and adult endothelial cells. Mature soluble VE-Statin is a 30‑32 kDa protein containing an N-terminal cysteine-rich EMI domain, followed by two EGF-like domains and a coiled‑coil region. Two isoforms of mouse VE-Statin have been reported. Isoform 2 shows a deletion of 13 amino acid residues between residues 236 to 248 of isoform 1. VE-Statin inhibits PDGF-BB-induced smooth muscle cell migration. The amino acid sequence of mouse VE-Statin is 76% and 80% identical to that of canine and human VE-Statin, respectively.

Long Name

Vascular Endothelial Statin/EGF-like Domain, Multiple 7

Entrez Gene IDs

51162 (Human)

Alternate Names

EGFL7; EGF-like protein 7; EGF-like-domain, multiple 7; epidermal growth factor-like protein 7; MEGF7; MGC111117; Multiple EGF-like domains protein 7; Multiple epidermal growth factor-like domains protein 7; NEU1 protein; NOTCH4-like protein; RP11-251M1.2; Vascular endothelial statin; VEStatin; VE-Statin; ZNEU1