Mouse Integrin alpha E/CD103 Antibody

Catalog #: MAB1990
1 Citation Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB1990-SP
MAB1990-100

Product Details

Citations (1)

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse Integrin alpha E/CD103 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Integrin alpha E/CD103 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse Integrin alpha 2, alpha 3, alpha 4, alpha 5, alpha M, alpha X, or recombinant human Integrin alpha 5 is observed.

Source

Monoclonal Rat IgG₁ Clone # 262523

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Integrin alpha E/CD103
Phe20-Asn1113 (Ser453Gly)
Accession # Q60677

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Mouse Integrin alpha E/CD103

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Integrin alpha E/CD103

The alpha E subunit, also known as CD103, forms a non-covalent heterodimer with Integrin beta 7. Integrin alpha E/ beta 7 is a receptor for E-Cadherin. Integrin alpha E is expressed on intra-epithelial lymphocytes and mediates adhesion of intra-epithelial lymphocytes to epithelial cell monolayers.

Entrez Gene IDs

3682 (Human); 16407 (Mouse); 83577 (Rat)

Alternate Names

antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; CD103 antigen; CD103; HML-1 antigen; HUMINAE; Integrin alpha E; integrin alpha-E; Integrin alpha-IEL; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alphapolypeptide); ITGAE; MGC141996; Mucosal lymphocyte 1 antigen

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Mouse Integrin alpha E/CD103 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b(high)Gr1(low) macrophages.
Authors: Schiechl G, Bauer B, Fuss I, Lang SA, Moser C, Ruemmele P, Rose-John S, Neurath MF, Geissler EK, Schlitt HJ, Strober W, Fichtner-Feigl S
J. Clin. Invest., 2011-04-25;121(5):1692-708.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry