Mouse IL-16 Antibody

Catalog # Availability Size / Price Qty
MAB1727
MAB1727-SP
Product Details
Citations (2)
FAQs
Supplemental Products
Reviews

Mouse IL-16 Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse IL-16 in direct ELISAs and Western blots. Shows approximately 50% cross‑reactivity with recombinant human (rh) IL-16 and no cross-reactivity with rmC-10, rhI-309, rhHCC-4, or rhHCC-1.
Source
Monoclonal Rat IgG2B Clone # 228109
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL-16
Ser1205-Ser1322
Accession # O54824
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Mouse IL‑16

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
Loading...
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IL-16

Interleukin 16 (IL-16), also known as lymphocyte chemoattractant factor (LCF), refers to the C-terminal peptide of pro-IL-16 isoform 1, which is a nuclear and cytoplasmic PDZ-containing protein. The C-terminus of pro-IL-16 is cleaved by Caspase-3, resulting in the release of secreted IL-16. Mature IL-16 has been shown to bind the cell surface receptor CD4 and functions as an immunomodulatory cytokine.

Long Name
Interleukin 16
Entrez Gene IDs
3603 (Human); 16170 (Mouse)
Alternate Names
FLJ16806; FLJ42735; FLJ44234; HsT19289; IL16; IL-16; interleukin 16 (lymphocyte chemoattractant factor); LCF; LCFprIL-16; lymphocyte chemoattractant factor; neuronal interleukin 16; NIL16; PRIL16; prointerleukin 16; pro-interleukin-16

Product Datasheets

You must select a language.

x

Citations for Mouse IL-16 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
Filter your results:

Filter by:

  1. Synovial Fluid Interleukin-16 Contributes to Osteoclast Activation and Bone Loss through the JNK/NFATc1 Signaling Cascade in Patients with Periprosthetic Joint Infection
    Authors: Y Chang, YM Hsiao, CC Hu, CH Chang, CY Li, SWN Ueng, MF Chen
    Int J Mol Sci, 2020-04-21;21(8):.
  2. Interleukin-16 Promotes Cardiac Fibrosis and Myocardial Stiffening in Heart Failure with Preserved Ejection Fraction
    Authors: Shunsuke Tamaki, Toshiaki Mano, Yasushi Sakata, Tomohito Ohtani, Yasuharu Takeda, Daisuke Kamimura et al.
    PLoS ONE

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs
Loading...

Reviews for Mouse IL-16 Antibody

There are currently no reviews for this product. Be the first to review Mouse IL-16 Antibody and earn rewards!

Have you used Mouse IL-16 Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review