Mouse Exostosin-like 2/EXTL2 Antibody

Catalog #: MAB2536 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB2536
MAB2536-SP

Product Details

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse Exostosin-like 2/EXTL2 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Exostosin-like 2/EXTL2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse EXTL1, recombinant human (rh) Exostosin-like 2/EXTL2, or rhEXTL3 is observed.

Source

Monoclonal Rat IgG_2A Clone # 339509

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Exostosin-like 2/EXTL2
Asn43-Met330
Accession # Q9ES89

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Mouse Exostosin-like 2/EXTL2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Exostosin-like 2/EXTL2

Exostosin-like 2/EXTL2 is a type II Golgi membrane protein with a C-terminal lumenal region that contains the catalytic domain. It is a glycosyl transferase that is required for the biosynthesis of heparan sulfate. The amino acid sequence of the mouse EXTL2 is 93%, 90%, 87% and 81% identical to that of rat, canine, human and chicken.

Entrez Gene IDs

2135 (Human); 58193 (Mouse)

Alternate Names

Alpha-1,4-N-acetylhexosaminyltransferase EXTL2; alpha-1,4-N-acteylhexosaminyltransferase; Alpha-GalNAcT EXTL2; EC 2.4.1.223; exostoses (multiple)-like 2; Exostosin like 2; Exostosin-like 2; EXTL2; EXTR2; EXT-related protein 2; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; processed exostosin-like 2