Mouse Exostosin-like 1/EXTL1 Antibody

Catalog #: MAB4214
2 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB4214
MAB4214-SP

Product Details

Citations (2)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse Exostosin-like 1/EXTL1 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Exostosin-like 1/EXTL1 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) EXTL1, rhEXTL2, rhEXTL3, or recombinant mouse EXTL2 is observed.

Source

Monoclonal Rat IgG_2A Clone # 353713

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Exostosin-like 1/EXTL1
Ala30-Pro669
Accession # Q9JKV7

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Mouse Exostosin-like 1/EXTL1

Immunoprecipitation

25 µg/mL

Conditioned cell culture medium spiked with Recombinant Mouse Exostosin-like 1/EXTL1, see our available Western blot detection antibodies

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Exostosin-like 1/EXTL1

Exostosin-like 1 (EXTL1) is a type II Golgi membrane protein and a glycosyl transferase that is required for the biosynthesis of heparan sulfate. The amino acid sequence of mouse EXTL1 is 92%, 76%, 75% and 74% identical to that of rat, chimpanzee, human and canine.

Entrez Gene IDs

2134 (Human); 56219 (Mouse); 313610 (Rat)

Alternate Names

alpha-N-acetylglucosaminyltransferase II; EC 2.4.1.224; exostoses (multiple)-like 1; Exostosin like 1; Exostosin-L; Exostosin-like 1; EXTL1; EXTLexostosin-like 1; glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Glucuronosyl-N-acetylglucosaminyl-proteoglycan4-alpha-N-acetylglucosaminyltransferase; glucuronyl-N-acetylglucosaminylproteoglycan alpha-1,4-N-acetylglucosaminyltransferase; MGC70794; Multiple exostosis-like protein

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Mouse Exostosin-like 1/EXTL1 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity
Authors: J Liu, Y Cheng, X Zhang, Y Chen, H Zhu, K Chen, S Liu, Z Li, X Cao
Cell Reports, 2023-01-18;42(1):111991.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry
Glycotranscriptome study reveals an enzymatic switch modulating glycosaminoglycan synthesis during B-cell development and activation.
Authors: Duchez S, Pascal V, Cogne N, Jayat-Vignoles C, Julien R, Cogne M
Eur. J. Immunol., 2011-11-10;41(12):3632-44.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA Development