Mouse C1qR1/CD93 Antibody Summary
Ala23-Asn572
Accession # O89103
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: C1qR1/CD93
C1q R1, also known as C1q Rp, CD93, Cell Surface Antigen AA4 and lymphocyte antigen 68, is a type I transmembrane protein. It contains a C-type lectin family domain and five EGF-like domains in its extracellular region, as well as a tyrosine kinase-recognition motif in its cytoplasmic region. It is most abundantly expressed on endothelial cells and platelets and is also expressed in neutrophils, glial cells and monocytes. C1q R1 is a marker for early multipotent hematopoietic cells and may participate in C1q/MBL/SPA-mediated enhancement of phagocytic function by monocytes.
Product Datasheets
Citations for Mouse C1qR1/CD93 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 7
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A novel CD93 polymorphism in non-obese diabetic (NOD) and NZB/W F1 mice is linked to a CD4+ iNKT cell deficient state
Authors: Ghazal Zekavat, Raha Mozaffari, Vanessa J. Arias, Susan Y. Rostami, Armen Badkerhanian, Andrea J. Tenner et al.
Immunogenetics
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Significance of Soluble CD93 in Type 2 Diabetes as a Biomarker for Diabetic Nephropathy: Integrated Results from Human and Rodent Studies
Authors: M Lee, HS Park, MY Choi, HZ Kim, SJ Moon, JY Ha, A Choi, YW Park, JS Park, EC Shin, CW Ahn, S Kang
J Clin Med, 2020-05-08;9(5):.
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SproutAngio: an open-source bioimage informatics tool for quantitative analysis of sprouting angiogenesis and lumen space
Authors: Beter, M;Abdollahzadeh, A;Pulkkinen, HH;Huang, H;Orsenigo, F;Magnusson, PU;Yl�-Herttuala, S;Tohka, J;Laakkonen, JP;
Scientific reports
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
CD93 promotes ?1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis
Authors: R Lugano, K Vemuri, D Yu, M Bergqvist, A Smits, M Essand, S Johansson, E Dejana, A Dimberg
J. Clin. Invest., 2018-06-25;128(8):3280-3297.
Species: Human, Mouse
Sample Types: Whole Tissue
Applications: IHC -
Membrane-associated CD93 regulates leukocyte migration and C1q-hemolytic activity during murine peritonitis.
Authors: Greenlee-Wacker MC, Briseno C, Galvan M, Moriel G, Velazquez P, Bohlson SS
J. Immunol., 2011-08-17;187(6):3353-61.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
Applications: ELISA Development -
Discovery and validation of biomarkers that respond to treatment with brivanib alaninate, a small-molecule VEGFR-2/FGFR-1 antagonist.
Authors: Ayers M, Fargnoli J, Lewin A, Wu Q, Platero JS
Cancer Res., 2007-07-15;67(14):6899-906.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
Mapping endothelial-cell diversity in cerebral cavernous malformations at single-cell resolution
Authors: Fabrizio Orsenigo, Lei Liu Conze, Suvi Jauhiainen, Monica Corada, Francesca Lazzaroni, Matteo Malinverno et al.
eLife
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