Human TREML1/TLT-1 Alexa Fluor® 488-conjugated Antibody Summary
Gln16-Ser160
Accession # Q86YW5
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of TREML1/TLT‑1 in Human Platelets by Flow Cytometry. Human peripheral blood platelets were stained with Mouse Anti-Human Integrin alpha 2b/CD41 APC-conjugated Monoclonal Antibody (Catalog # FAB7616A) and either (A) Rat Anti-Human TREML1/TLT-1 Alexa Fluor® 488 Monoclonal Antibody (Catalog # FAB2934G) or (B) Rat IgG2B Isotype Control (Catalog # IC013G). View our protocol for Staining Membrane-associated Proteins.
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Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: TREML1/TLT-1
TREML1 is an inhibitory type I transmembrane protein that has two cytoplasmic ITIMs (Immunoreceptor Tyrosine-based Inhibition Motif). A splice variant lacking ITIMs in its cytoplasmic domain also exists. TREML1 is found only in platelets and megakaryocytes.
Product Datasheets
Product Specific Notices
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Citation for Human TREML1/TLT-1 Alexa Fluor® 488-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
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The Toll-Like Receptor 2 Ligand Pam2CSK4 Activates Platelet Nuclear Factor-kappa B and Bruton’s Tyrosine Kinase Signaling to Promote Platelet-Endothelial Cell Interactions
Authors: Iván Parra-Izquierdo, Hari Hara Sudhan Lakshmanan, Alexander R. Melrose, Jiaqing Pang, Tony J. Zheng, Kelley R. Jordan et al.
Frontiers in Immunology
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