Human STAMP2/STEAP4 Alexa Fluor® 405-conjugated Antibody

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FAB4626V-100UG
R&D Systems Antibodies
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Human STAMP2/STEAP4 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human STAMP2-transfected NS0 cells but not irrelevant transfectants in flow cytometry.
Source
Monoclonal Mouse IgG2b Clone # 418714
Immunogen
NS0 mouse myeloma cell line transfected with human STAMP2
Met1-His459
Accession # EAW76907
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
Human STAMP2 transfected HEK293 human cell line

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: STAMP2/STEAP4

Human STAMP2, also called Steap4 or TIARP (TNF-alpha -induced adipose-related protein), is a 55 kDa, 459 aa, 6-transmembrane (TM) member of the Steap family of metalloreductases. It is induced by androgens in androgen-regulated prostate cells, and is up‑regulated during adipocyte differentiation by TNF-alpha. Full-length human and mouse STAMP2 share 80% aa identity. A 283 aa variant lacks a portion of the oxidoreductase domain and three TM domains. STAMP2 is present in the Golgi complex and early endosomes in addition to the cell surface.

Long Name
Six Transmembrane Protein of Prostate 2
Entrez Gene IDs
79689 (Human); 117167 (Mouse)
Alternate Names
EC 1.16.1; EC 1.16.1.-; FLJ23153; Six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; STAMP2; STAMP2DKFZp666D049; STEAP family member 4; STEAP4; TIARP; TIARPsix transmembrane prostate protein 2; TNFAIP9; Tumor necrosis factor, alpha-induced protein 9metalloreductase STEAP4; tumor necrosis-alpha-induced adipose-related protein

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Product Specific Notices


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

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