Human/Rat SOX10 NorthernLights™ NL557-conjugated Antibody

Catalog #: NL2864R
2 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
NL2864R

All SOX10 Antibodies

Product Details

Citations (2)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Rat SOX10 NorthernLights™ NL557-conjugated Antibody Summary

Species Reactivity

Human, Rat

Specificity

Detects human and rat SOX10. Epitope-mapping experiments indicated that clone 20B7 recognizes a determinant in the first 65 amino acids, which contains sequences unique to SOX10 (1).

Source

Monoclonal Mouse IgG1 Clone # 20B7

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

NL557 (Excitation= 557 nm, Emission= 574 nm)

Applications

Recommended Concentration

Sample

Immunocytochemistry

Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: SOX10

SOX10 belongs to the SOX family of transcription factors which display diverse roles during development. In the central nervous system, SOX10 is required for the terminal differentiation of oligodendrocytes and myelination. In the peripheral nervous system, SOX10 maintains pluripotency of neural crest stem cells and suppresses neuronal differentiation.

References

Lo, L. et al. (2002) Development 129:1553.

Long Name

Transcription Factor SOX10

Entrez Gene IDs

6663 (Human)

Alternate Names

DOM; MGC15649; PCWH; SOX10; SRY (sex determining region Y)-box 10; SRY-related HMG-box gene 10; transcription factor SOX-10; WS4; WS4C; WS4mouse, human homolog of

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Human/Rat SOX10 NorthernLights™ NL557-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types
Authors: G Shireby, EL Dempster, S Policicchi, RG Smith, E Pishva, B Chioza, JP Davies, J Burrage, K Lunnon, D Seiler Vel, S Love, A Thomas, K Brookes, K Morgan, P Francis, E Hannon, J Mill
Nature Communications, 2022-09-24;13(1):5620.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPK alpha Activity
Authors: Qinjie Weng, Jiajia Wang, Jiaying Wang, Biqin Tan, Jing Wang, Haibo Wang et al.
Scientific Reports