Human Opticin Antibody

Catalog #: MAB3148 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB3148
MAB3148-SP

All Opticin Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Opticin Antibody Summary

Specificity

Detects human Opticin in direct ELISAs and Western blots. In direct ELIAs and Western blots, no cross-reactivity with recombinant mouse Opticin is observed.

Source

Monoclonal Rat IgG_2A Clone # 361328

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Opticin
Ala20-Thr332
Accession # Q9UBM4

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Purity

Protein A or G purified from hybridoma culture supernatant

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human Opticin

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Opticin

Opticin (Oculoglycan) is a member of the small leucine-rich proteoglycan (SLRP) family with homology to class III extracellular matrix family members Epiphycan and Mimecan. It forms a 90 kDa noncovalent dimer that is a component of vitreous collagen fibrils in the eye and is also expressed in the retina, iris, ligaments and skin. Mature human Opticin shares 73% and 65% aa identity with mouse and rat, respectively. Mutations of Opticin have been associated with age-related macular degeneration.

Entrez Gene IDs

26254 (Human); 269120 (Mouse)

Alternate Names

oculoglycan; Oculogylcan; OPT; OPTC; Opticin