Human FPRL2/FPR3 Antibody

Name: Human FPRL2/FPR3 Antibody
Brand: R&D Systems
SKU: MAB3896
Rating: 3 (1 reviews)

Catalog #: MAB3896
3 Citations 1 Review Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB3896
MAB3896-SP

All FPRL2/FPR3 Antibodies

Product Details

Citations (3)

FAQs

Supplemental Products

Reviews (1)

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human FPRL2/FPR3 Antibody Summary

Specificity

Detects human FPRL2. Stains human FPRL2 transfectants but not irrelevant transfectants.

Source

Monoclonal Mouse IgG_2B Clone # 374822

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

HEK293 human embryonic kidney cell line transfected with human FPRL2
Met1-Met352
Accession # P25089

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Endotoxin Level

<0.10 EU per 1 μg of the antibody by the LAL method.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Flow Cytometry

0.25 µg/10⁶ cells

NS0 mouse myeloma cell line transfected with human FPRL2

CyTOF-ready

Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: FPRL2/FPR3

FPRL2, also known as FMLP receptor-like 2, is a 40 kDa 7TM protein that is expressed on monocytes and dendritic cells. It interacts with formyl and acetyl peptides to attract these cells to sites of infection. FPRL2 signaling also inhibits DC maturation. Human FPRL2 shares 63% and 62% amino acid sequence identity with mouse and rat FPRL2, respectively.

Long Name

Formyl Peptide Receptor-like 2

Entrez Gene IDs

2359 (Human); 14294 (Mouse)

Alternate Names

FMLP-R-II; FMLPY; formyl peptide receptor 3; Formyl peptide receptor-like 2FMLP-related receptor II; FPR3; FPRH1; FPRH1FPRH2; FPRH2; FPRL2; FPRL2FML2_HUMAN; N-formyl peptide receptor 3; RMLP-R-I

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Human FPRL2/FPR3 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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Amyloid beta and its naturally occurring N-terminal variants are potent activators of human and mouse formyl peptide receptor 1
Authors: L Busch, Z Al Taleb, YL Tsai, VTT Nguyen, Q Lu, CV Synatschke, K Endres, B Bufe
The Journal of Biological Chemistry, 2022-10-27;0(0):102642.
Species: Human
Sample Types: Whole Cells
Applications: ICC
Intracellular formyl peptide receptor regulates naï¿½ve CD4 T cell migration
Authors: HY Lee, YS Jeong, M Lee, HS Kweon, YH Huh, JS Park, JE Hwang, K Kim, YS Bae
Biochem. Biophys. Res. Commun., 2018-02-08;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis.
Authors: Prevete N, Liotti F, Visciano C, Marone G, Melillo R, de Paulis A
Oncogene, 2014-09-29;34(29):3826-38.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry