Human delta-Sarcoglycan Antibody

Catalog #: AF2778 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF2778
AF2778-SP

Product Details

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human delta-Sarcoglycan Antibody Summary

Specificity

Detects human δ-Sarcoglycan in direct ELISAs and Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human δ-Sarcoglycan isoform 1
Met1-Glu232
Accession # Q92629

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human δ-Sarcoglycan

Immunohistochemistry

5-15 µg/mL

Immersion fixed frozen sections of human fetal brain

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: delta-Sarcoglycan

Delta-sarcoglycan is one of six known sarcoglycans, which are type I ( alpha - and epsilon -) or type II ( beta -, gamma -, δ- or zeta -) transmembrane glycoproteins. Sarcoglycans associate in different combinations in a tissue-specific manner, to form heterotetrameric, pentameric and hexameric membrane glycoprotein complexes (SGC). SGC interacts laterally with the dystroglycan complex, and both complexes are components of the dystrophin-associated glycoprotein complex (DGC), which forms a link between the cytoskeleton and the extracellular matrix. Mutations in sarcoglycans are associated with recessive autosomally inherited muscular dystrophy.

Entrez Gene IDs

6444 (Human)

Alternate Names

35 kDa dystrophin-associated glycoprotein; 35DAG; 35kD dystrophin-associated glycoprotein; CMD1L; CMD1LSG-delta; DAGD; deltaSarcoglycan; delta-Sarcoglycan; delta-SG; dystrophin associated glycoprotein, delta sarcoglycan; LGMD2F; MGC22567; placental delta sarcoglycan; sarcoglycan, delta (35kD dystrophin-associated glycoprotein); sarcoglycan, delta (35kDa dystrophin-associated glycoprotein); SGCD; SGCDP; SGD