Human CD31/PECAM-1 APC-conjugated Antibody Summary
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of CD31/PECAM‑1 in Human Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CD31/PECAM-1 APC-conjugated Monoclonal Antibody (Catalog # FAB3567A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.
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Detection of CD31/PECAM-1 in THP-1 Human Cell Line by Flow Cytometry. THP-1 human acute monocytic leukemia cell line was stained with Mouse Anti-Human CD31/PECAM-1 APC-conjugated Monoclonal Antibody (Catalog # FAB3567A, filled histogram) or isotype control antibody (IC002A, open histogram). Staining was performed using our Membrane-Associated Staining protocol.
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CD31/PECAM-1 Specificity is Shown by Flow Cytometry in Knockout Cell Line. CD31/PECAM-1 knockout THP-1 human acute monocytic leukemia cell line was stained with Mouse Anti-Human CD31/PECAM-1 APC-conjugated Monoclonal Antibody (Catalog # FAB3567A, filled histogram) or isotype control antibody (IC002A, open histogram). No staining in the CD31/PECAM-1 knockout THP-1 cell line was observed. Staining was performed using our Staining Membrane-associated Proteins protocol.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CD31/PECAM-1
The CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions and on T cell subsets, and to a lesser extent on platelets and most other leukocytes such as monocytes and neutrophils. CD31 binds to itself homotypically, and also to the leukocyte integrin alpha v beta 3 heterotypically. CD31 is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells. CD31 has been found in human plasma, and the presence of this circulating isoform is suggested to modulate the transendothelial migration of leukocytes.
Product Datasheets
Citations for Human CD31/PECAM-1 APC-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
9
Citations: Showing 1 - 9
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Tumor-Derived cGAMP Regulates Activation of the Vasculature
Authors: Marco Campisi, Shriram K. Sundararaman, Sarah E. Shelton, Erik H. Knelson, Navin R. Mahadevan, Ryohei Yoshida et al.
Frontiers in Immunology
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Proteomic Profiling of Native Unpassaged and Culture‐Expanded Mesenchymal Stromal Cells (MSC)
Authors: Erika Moravcikova, E. Michael Michael Meyer, Mirko Corselli, Vera S. Donnenberg, Albert D. Donnenberg
Cytometry Part A
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Highly elastic and bioactive bone biomimetic scaffolds based on platelet lysate and biomineralized cellulose nanocrystals
Authors: JP Ribeiro, RMA Domingues, PS Babo, LP Nogueira, JE Reseland, RL Reis, M Gomez-Flor, ME Gomes
Carbohydrate polymers, 2022-05-20;292(0):119638.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Engagement of the CXCL12-CXCR4 Axis in the Interaction of Endothelial Progenitor Cell and Smooth Muscle Cell to Promote Phenotype Control and Guard Vascular Homeostasis
Authors: SF Mause, E Ritzel, A Deck, F Vogt, EA Liehn
International Journal of Molecular Sciences, 2022-01-14;23(2):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Characterization of gene expression changes in human neural stem cells and endothelial cells modeling a neurovascular microenvironment
Authors: CH Chou, M Modo
Brain Res. Bull., 2020-02-21;158(0):9-19.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Monocytes as Endothelial Progenitor Cells (EPCs), Another Brick in the Wall to Disentangle Tumor Angiogenesis
Authors: F Lopes-Coel, F Silva, S Gouveia-Fe, C Martins, N Lopes, G Domingues, C Brito, AM Almeida, SA Pereira, J Serpa
Cells, 2020-01-01;9(1):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Donor lymphocyte count and thymic activity predict lymphocyte recovery and outcomes after matched-sibling hematopoietic stem cell transplant.
Authors: McIver Z, Melenhorst J, Wu C, Grim A, Ito S, Cho I, Hensel N, Battiwalla M, Barrett A
Haematologica, 2012-10-12;98(3):346-52.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Human hepatocellular carcinoma tumor-derived endothelial cells manifest increased angiogenesis capability and drug resistance compared with normal endothelial cells.
Authors: Xiong YQ, Sun HC, Zhang W
Clin. Cancer Res., 2009-07-28;15(15):4838-46.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Regenerative Therapy and Cancer: In Vitro and In Vivo Studies of the Interaction Between Adipose-Derived Stem Cells and Breast Cancer Cells from Clinical Isolates
Authors: Ludovic Zimmerlin, Albert D. Donnenberg, J. Peter Rubin, Per Basse, Rodney J. Landreneau, Vera S. Donnenberg
Tissue Engineering Part A
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