Human C1qR1/CD93 Biotinylated Antibody

Catalog #: BAF2379
1 Citation Datasheet / COA / SDS

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BAF2379

All C1qR1/CD93 Antibodies

Product Details

Citations (1)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human C1qR1/CD93 Biotinylated Antibody Summary

Species Reactivity

Human

Specificity

Detects human C1q R1/CD93 in Western blots. In Western blots, less than 5% cross-reactivity with recombinant mouse C1q R1 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human C1q R1/CD93
Ala24-Lys580
Accession # Q9NPY3

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human C1q R1/CD93

Flow Cytometry

2.5 µg/10⁶ cells

Human peripheral blood monocytes

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: C1qR1/CD93

C1q R1, also known as CD93, C1q R, and C1q RP, is a single chain glycoprotein expressed on cells of myeloid origin, endothelial cells, and hematopoietic progenitor cells. In vitro, this molecule may mediate the enhancement of phagocytosis upon interaction with soluble defense collagens (1, 2).

References

Kim, T.S. et al. (2000) Mol. Immunol. 37:377.
Dean, Y.D. and P. Gasque (2001) Eur. J. Immunol. 31:1370.

Long Name

Complement Component C1q Receptor

Entrez Gene IDs

22918 (Human); 17064 (Mouse); 84398 (Rat)

Alternate Names

AA4 Antigen; C1q R1; C1q receptor 1; C1q Rp; C1q/MBL/SPA receptor; C1qR(P); C1qR1; C1qRp; CD93 antigenC1qR; CD93 molecule; CD93; CDw93C1QR1; Collectin Receptor; Complement component 1 q subcomponent receptor 1; complement component 1, q subcomponent, receptor 1; complement component C1q receptor; dJ737E23.1; ECSM3; Ly68; Matrix-remodeling-associated protein 4; matrix-remodelling associated 4; MXRA4

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Human C1qR1/CD93 Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Plasma CD93 concentration is a potential novel biomarker for coronary artery disease.
Authors: Malarstig A, Silveira A, Wagsater D, Ohrvik J, Backlund A, Samnegard A, Khademi M, Hellenius ML, Leander K, Olsson T, Uhlen M, de Faire U, Eriksson P, Hamsten A
J. Intern. Med., 2011-03-21;270(0):229-36.
Species: Human
Sample Types: Plasma
Applications: ELISA Development