Bropirimine
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Description: Immunomodulatory and antitumor compound
Chemical Name: 2-Amino-5-bromo-6-phenyl-4(3H)-pyrimidone
Purity: ≥99%
Biological Activity
Bropirimine is a immunomodulatory and antitumor compound. Induces interferon (IFN)-α/β production; augments natural killer (NK) cell activity. Orally active.Technical Data
M.Wt:
266.09
Formula:
C10H8BrN3O
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
56741-95-8
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Antitumor effects of oral administration of an IF.-inducing pyrimidinone, Bropirimine, on murine renal-cell carcinoma.
Fujioka et al.
Cancer Chemother.Pharmacol., 1995;36:7 -
In vitro antitumor activity of bropirimine against urinary bladder tumor cells.
Tei et al.
Anticancer Res., 2002;22:1667
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