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8-oxo-dG Antibody

Catalog #: 4354-MC-050
71 Citations 4 Reviews Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4354-MC-050
Detection of Rat 8-oxo-dG by Immunocytochemistry/ Immunofluorescence
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Product Details
Citations (71)
FAQs
Supplemental Products
Reviews (4)
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

8-oxo-dG Antibody Summary

Specificity
This mouse monoclonal antibody specifically binds to 8-hydroxy-2'- deoxyguanosine within DNA in H2O2-treated cells.
Source
Monoclonal Mouse IgG2B Clone # 15A3
Purification
Protein A or G purified from ascites
Immunogen
8-oxo-dG-conjugated-KLH
Formulation
This antibody is provided as purified immunoglobulin from mouse ascites at 0.5 mg/ml in 1X PBS containing 0.1% sodium azide, 50% glycerol.
Label
Unconjugated

Applications

Recommended Concentration
Sample
ELISA
Empirical determination will be required for optimal results.
 
Immunohistochemistry
1:250 dilution
Paraffin embedded rat thymus tissue
Immunocytochemistry
1:250 dilution

H2O2 treated MCF 10A human breast epithelial cell line

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunocytochemistry/ Immunofluorescence Detection of Rat 8-oxo-dG by Immunocytochemistry/ Immunofluorescence View Larger

Detection of Rat 8-oxo-dG by Immunocytochemistry/ Immunofluorescence Expression of apoptotic factors in denervated muscle 2 weeks after denervation.(A) Expression of Bcl-2, Bad, and Bax in denervated muscle subjected to different treatment (B) Quantitative analysis of apoptotic markers in different treatment groups (C) The expression of 8-oxo-dG in normal, control, ES, and AFS group. (D) The representative of western blot analysis of 8-oxo-dG related to different treatment (n = 2) (F) Quantitative analysis of caspase-3 in different treatment groups Bar length = 100 μm. R = right, L = left, N = 6 for each group, * p<0.05 and **p<0.01indicated a statistical difference compared to the control group; # p<0.05 indicated a statistical difference as compared to the ES group. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/25945496), licensed under a CC-BY license. Not internally tested by R&D Systems.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: 8-oxo-dG

The production of 8-Hydroxyguanine (8-oxo-dG) is almost exclusively elicited by oxidative stress. Polymerases preferentially insert adenine opposite 8-oxo-dG. Therefore, oxidatively damaged adducts, without repair, are susceptible to G to T transitions.

Long Name
8-Hydroxyguanine
Alternate Names
8-OHG; 8oxodG; 8-oxo-dG

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Citations for 8-oxo-dG Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

71 Citations: Showing 1 - 10
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  1. Spermidine rescues the deregulated autophagic response to oxidative stress of osteoarthritic chondrocytes
    Authors: D'Adamo S, Cetrullo S, Guidotti S et al.
    Free Radic. Biol. Med.
  2. SIRT6 promotes metastasis and relapse in HER2-positive breast cancer
    Authors: Andreani, C;Bartolacci, C;Persico, G;Casciaro, F;Amatori, S;Fanelli, M;Giorgio, M;Galié, M;Tomassoni, D;Wang, J;Zhang, X;Bick, G;Coppari, R;Marchini, C;Amici, A;
    Scientific reports
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  3. G6PD Maintains Redox Homeostasis and Biosynthesis in LKB1-Deficient KRAS-Driven Lung Cancer
    Authors: Lan, T;Arastu, S;Wang, S;Lam, J;Wang, W;Bhatt, V;Lopes, EC;Hu, Z;Sun, M;Luo, X;Ghergurovich, JM;Li, C;Su, X;Rabinowitz, JD;White, E;Guo, JY;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  4. Selective effects of estradiol on human corneal endothelial cells
    Authors: Han, S;Mueller, C;Wuebbolt, C;Kilcullen, S;Nayyar, V;Calle Gonzalez, B;Mahdavi Fard, A;Floss, JC;Morales, MJ;Patel, SP;
    Scientific reports
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  5. Individual cell types in C. elegans age differently and activate distinct cell-protective responses
    Authors: Roux, AE;Yuan, H;Podshivalova, K;Hendrickson, D;Kerr, R;Kenyon, C;Kelley, D;
    Cell reports
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  6. An immunomodulating peptide to counteract solar radiation-induced immunosuppression and DNA damage
    Authors: Agrez, M;Rybchyn, MS;De Silva, WGM;Mason, RS;Chandler, C;Piva, TJ;Thurecht, K;Fletcher, N;Liu, F;Subramaniam, G;Howard, CB;Blyth, B;Parker, S;Turner, D;Rzepecka, J;Knox, G;Nika, A;Hall, A;Gooding, H;Gallagher, L;
    Scientific reports
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  7. Selective effects of estradiol on human corneal endothelial cells
    Authors: Han, S;Mueller, C;Wuebbolt, C;Kilcullen, S;Nayyar, V;Calle Gonzalez, B;Mahdavi Fard, A;Floss, JC;Morales, MJ;Patel, SP;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Upregulation of NADH/NADPH oxidase 4 by angiotensin II induces podocyte apoptosis
    Authors: Tae-Sun Ha, Su-Bin Seong, Dong-Soo Ha, Seung Jung Kim
    Kidney Research and Clinical Practice
  9. LMP1 mediates tumorigenesis through persistent epigenetic modifications and PGC1? upregulation
    Authors: Chen S, Zhang P, Feng J et al.
    Oncology reports
  10. Neutral amino acid transporter SLC38A2 protects renal medulla from hyperosmolarity-induced ferroptosis
    Authors: Du C, Xu H, Cao C et al.
    eLife
  11. Inhibitors of Keap1-Nrf2 protein-protein interaction reduce estrogen responsive gene expression and oxidative stress in estrogen receptor-positive breast cancer
    Authors: T Xie, H Zahid, AR Ali, R Joyce, G Yang, C Winz, Y Le, R Zhou, P Furmanski, L Hu, N Suh
    Toxicology and Applied Pharmacology, 2023-01-09;460(0):116375.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  12. Artificial gravity partially protects space-induced neurological deficits in Drosophila melanogaster
    Authors: SD Mhatre, J Iyer, J Petereit, RM Dolling-Bo, A Tyryshkina, AM Paul, R Gilbert, M Jensen, RJ Woolsey, S Anand, MB Sowa, DR Quilici, SV Costes, S Girirajan, S Bhattachar
    Cell Reports, 2022-09-06;40(10):111279.
    Species: Drosophila
    Sample Types: Whole Tissue
    Applications: IHC
  13. Downregulating Mitochondrial DNA Polymerase gamma in the Muscle Stimulated Autophagy, Apoptosis, and Muscle Aging-Related Phenotypes in Drosophila Adults
    Authors: M Ozaki, TD Le, YH Inoue
    Biomolecules, 2022-08-11;12(8):.
    Species: Drosophila
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  14. Interplay between H3K36me3, methyltransferase SETD2, and mismatch recognition protein MutSalpha facilitates processing of oxidative DNA damage in human cells
    Authors: S Guo, J Fang, W Xu, J Ortega, CY Liu, L Gu, Z Chang, GM Li
    The Journal of Biological Chemistry, 2022-06-03;298(7):102102.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  15. Tumor suppressor PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7/autophagy to suppress neurodegeneration
    Authors: Y Huo, A Sawant, Y Tan, AH Mahdi, T Li, H Ma, V Bhatt, R Yan, J Coleman, CF Dreyfus, JY Guo, MM Mouradian, E White, B Xia
    PloS Genetics, 2022-04-11;18(4):e1010138.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  16. Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair proteins
    Authors: N Kumar, AF Theil, V Roginskaya, Y Ali, M Calderon, SC Watkins, RP Barnes, PL Opresko, A Pines, H Lans, W Vermeulen, B Van Houten
    Nature Communications, 2022-02-21;13(1):974.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  17. Oxidative DNA Damage and Cisplatin Neurotoxicity Is Exacerbated by Inhibition of OGG1 Glycosylase Activity and APE1 Endonuclease Activity in Sensory Neurons
    Authors: A Behrouzi, H Xia, EL Thompson, MR Kelley, JC Fehrenbach
    International Journal of Molecular Sciences, 2022-02-08;23(3):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  18. Maternal diabetes-mediated RORA suppression in mice contributes to autism-like offspring through inhibition of aromatase
    Authors: Hong Yu, Yanbin Niu, Guohua Jia, Yujie Liang, Baolin Chen, Ruoyu Sun et al.
    Communications Biology
  19. Sonlicromanol improves neuronal network dysfunction and transcriptome changes linked to m.3243A>G heteroplasmy in iPSC-derived neurons
    Authors: Teun M. Klein Gunnewiek, Anouk H.A. Verboven, Iris Pelgrim, Mark Hogeweg, Chantal Schoenmaker, Herma Renkema et al.
    Stem Cell Reports
  20. Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders
    Authors: K Linda, EI Lewerissa, AHA Verboven, M Gabriele, M Frega, TM Klein Gunn, L Devilee, E Ulferts, M Hommersom, A Oudakker, C Schoenmake, H van Bokhov, D Schubert, G Testa, DA Koolen, BBA de Vries, N Nadif Kasr
    Autophagy, 2021-07-21;0(0):20-Jan.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  21. Glutaminase inhibition with telaglenastat (CB-839) improves treatment response in combination with ionizing radiation in head and neck squamous cell carcinoma models
    Authors: Christina A. Wicker, Brian G. Hunt, Sunil Krishnan, Kathryn Aziz, Shobha Parajuli, Sarah Palackdharry et al.
    Cancer Letters
  22. Pterostilbene accelerates wound healing by modulating diabetes-induced estrogen receptor beta suppression in hematopoietic stem cells
    Authors: Weiguo Xie, Xueqing Zhou, Weigang Hu, Zhigang Chu, Qiongfang Ruan, Haimou Zhang et al.
    Burns & Trauma
  23. Maternal Diabetes-Induced Suppression of Oxytocin Receptor Contributes to Social Deficits in Offspring
    Authors: Jianbo Liu, Yujie Liang, Xing Jiang, Jianchang Xu, Yumeng Sun, Zichen Wang et al.
    Frontiers in Neuroscience
  24. Bixin Attenuates High-Fat Diet-Caused Liver Steatosis and Inflammatory Injury through Nrf2/PPAR&alpha Signals
    Authors: S Tao, Y Yang, J Li, H Wang, Y Ma
    Oxidative Medicine and Cellular Longevity, 2021-02-02;2021(0):6610124.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  25. Detection of genetic variation and base modifications at base-pair resolution on both DNA and RNA
    Authors: Zhen Wang, Jérôme Maluenda, Laurène Giraut, Thibault Vieille, Andréas Lefevre, David Salthouse et al.
    Communications Biology
  26. Oxidative Damage and Antioxidant Response in Frontal Cortex of Demented and Nondemented Individuals with Alzheimer's Neuropathology
    Authors: Anna Fracassi, Michela Marcatti, Olga Zolochevska, Natalie Tabor, Randall Woltjer, Sandra Moreno et al.
    The Journal of Neuroscience
  27. The ubiquitin E3 ligase TRIM21 promotes hepatocarcinogenesis by suppressing the p62-Keap1-Nrf2 antioxidant pathway
    Authors: F Wang, Y Zhang, J Shen, B Yang, W Dai, J Yan, S Maimouni, HQ Daguplo, S Coppola, Y Gao, Y Wang, Z Du, K Peng, H Liu, Q Zhang, F Tang, P Wang, S Gao, Y Wang, WX Ding, G Guo, F Wang, WX Zong
    Cellular and Molecular Gastroenterology and Hepatology, 2021-01-19;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  28. Deletion of KLF10 Leads to Stress-Induced Liver Fibrosis upon High Sucrose Feeding
    Authors: J Lee, AR Oh, HY Lee, YA Moon, HJ Lee, JY Cha
    International Journal of Molecular Sciences, 2020-12-30;22(1):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  29. Betulinic Acid Inhibits Endometriosis Through Suppression of Estrogen Receptor beta Signaling Pathway
    Authors: Dongfang Xiang, Min Zhao, Xiaofan Cai, Yongxia Wang, Lei Zhang, Helen Yao et al.
    Front Endocrinol (Lausanne)
  30. Targeted DNA oxidation by LSD1-SMAD2/3 primes TGF-&beta1/ EMT genes for activation or repression
    Authors: A Pezone, ML Taddei, A Tramontano, J Dolcini, FL Boffo, M De Rosa, M Parri, S Stinziani, G Comito, A Porcellini, G Raugei, D Gackowski, E Zarakowska, R Olinski, A Gabrielli, P Chiarugi, EV Avvediment
    Nucleic Acids Res., 2020-09-18;0(0):.
  31. Maternal Diabetes Induces Immune Dysfunction in Autistic Offspring Through Oxidative Stress in Hematopoietic Stem Cells
    Authors: Jianping Lu, Meifang Xiao, Xiaoling Guo, Yujie Liang, Min Wang, Jianchang Xu et al.
    Frontiers in Psychiatry
  32. Ligand-induced gene activation is associated with oxidative genome damage whose repair is required for transcription
    Authors: S Sengupta, H Wang, C Yang, B Szczesny, ML Hegde, S Mitra
    Proc. Natl. Acad. Sci. U.S.A., 2020-08-21;0(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP, Co-Immunoprecipitation
  33. BRAF Mutant Melanoma Adjusts to BRAF/MEK Inhibitors via Dependence on Increased Antioxidant SOD2 and Increased Reactive Oxygen Species Levels
    Authors: L Yuan, R Mishra, H Patel, S Alanazi, X Wei, Z Ma, JT Garrett
    Cancers (Basel), 2020-06-23;12(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  34. DNA damage induced during mitosis undergoes DNA repair synthesis
    Authors: V Gomez Godi, S Kabbara, A Sherman, T Wu, S Cohen, X Kong, JL Maravillas, Z Shi, D Preece, K Yokomori, MW Berns
    PLoS ONE, 2020-04-28;15(4):e0227849.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  35. Berberine Ameliorates Prenatal Dihydrotestosterone Exposure-Induced Autism-Like Behavior by Suppression of Androgen Receptor
    Authors: Dongfang Xiang, Jianping Lu, Chongxia Wei, Xiaofan Cai, Yongxia Wang, Yujie Liang et al.
    Frontiers in Cellular Neuroscience
  36. Cardiovascular Changes Related to Metabolic Syndrome: Evidence in Obese Zucker Rats
    Authors: I Martinelli, D Tomassoni, M Moruzzi, P Roy, C Cifani, F Amenta, SK Tayebati
    Int J Mol Sci, 2020-03-16;21(6):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  37. Lamin A/C promotes DNA base excision repair
    Authors: S Maynard, G Keijzers, M Akbari, MB Ezra, A Hall, M Morevati, M Scheibye-K, S Gonzalo, J Bartek, VA Bohr
    Nucleic Acids Res., 2019-12-16;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  38. IL-4 and IL-17A Cooperatively Promote Hydrogen Peroxide Production, Oxidative DNA Damage, and Upregulation of Dual Oxidase 2 in Human Colon and Pancreatic Cancer Cells
    Authors: Y Wu, MM Konaté, J Lu, H Makhlouf, R Chuaqui, S Antony, JL Meitzler, MJ Difilippan, H Liu, A Juhasz, G Jiang, I Dahan, K Roy, JH Doroshow
    J. Immunol., 2019-09-23;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  39. PRMT5 Modulates Splicing for Genome Integrity and Preserves Proteostasis of Hematopoietic Stem Cells
    Authors: DQ Tan, Y Li, C Yang, J Li, SH Tan, DWL Chin, A Nakamura-I, H Yang, T Suda
    Cell Rep, 2019-02-26;26(9):2316-2328.e6.
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: ICC
  40. PPAR? Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis
    Authors: CG Li, C Mahon, NM Sweeney, E Verschuere, V Kantamani, D Li, JK Hennigs, DP Marciano, I Diebold, O Abu-Halawa, M Elliott, S Sa, F Guo, L Wang, A Cao, C Guignabert, J Sollier, NP Nickel, M Kaschwich, KA Cimprich, M Rabinovitc
    Cell Rep, 2019-01-29;26(5):1333-1343.e7.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  41. SIRT1 activation promotes angiogenesis in diabetic wounds by protecting endothelial cells against oxidative stress
    Authors: X Li, G Wu, F Han, K Wang, X Bai, Y Jia, Z Li, W Cai, W Zhang, L Su, D Hu
    Arch. Biochem. Biophys., 2018-11-17;661(0):117-124.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  42. Degraded melanocores are incompetent to protect epidermal keratinocytes against UV damage
    Authors: WJ Yi, MY Su, Y Shi, S Jiang, SZ Xu, TC Lei
    Cell Cycle, 2018-04-25;0(0):1-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  43. Trajectory of Parvalbumin Cell Impairment and Loss of Cortical Inhibition in Traumatic Brain Injury.
    Authors: Hsieh T, Lee H, Hameed M, Pascual-Leone A, Hensch T, Rotenberg A
    Cereb Cortex, 2017-12-01;27(12):5509-5524.
  44. Human mesenchymal stem cells with enhanced telomerase activity acquire resistance against oxidative stress-induced genomic damage.
    Authors: Trachana V, Petrakis S, Fotiadis Z, Siska E, Balis V, Gonos E, Kaloyianni M, Koliakos G
    Cytotherapy, 2017-04-25;19(7):808-820.
  45. Endogenous catalase delays high-fat diet-induced liver injury in mice.
    Authors: Piao L, Choi J, Kwon G, Ha H
    Korean J Physiol Pharmacol, 2017-04-21;21(3):317-325.
  46. Prevention of Axonal Degeneration by Perineurium Injection of Mitochondria in a Sciatic Nerve Crush Injury Model
    Authors: CC Kuo, HL Su, TL Chang, CY Chiang, ML Sheu, FC Cheng, CJ Chen, J Sheehan, HC Pan
    Neurosurgery, 2017-03-01;80(3):475-488.
    Species: Rat
    Sample Types: Cell Lysates, Whole Cells
    Applications: ICC, Western Blot
  47. Delayed treatment with fenofibrate protects against high-fat diet-induced kidney injury in mice: the possible role of AMPK autophagy.
    Authors: Sohn M, Kim K, Uddin M, Lee G, Hwang I, Kang H, Kim H, Lee J, Ha H
    Am J Physiol Renal Physiol, 2016-07-27;312(2):F323-F334.
  48. Endothelin Receptor A Antagonism Prevents Damage to Glycogen-Rich Placental Cells Following Uterine Ischemia-Reperfusion in the Rat.
    Authors: Thaete L, Khan S, Neerhof M
    Reprod Sci, 2016-04-28;23(11):1518-1525.
  49. L-Lactate-Mediated Neuroprotection against Glutamate-Induced Excitotoxicity Requires ARALAR/AGC1.
    Authors: Llorente-Folch I, Rueda C, Perez-Liebana I, Satrustegui J, Pardo B
    J Neurosci, 2016-04-20;36(16):4443-56.
  50. Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes.
    Authors: Polyzos A, Holt A, Brown C, Cosme C, Wipf P, Gomez-Marin A, Castro M, Ayala-Pena S, McMurray C
    Hum Mol Genet, 2016-02-21;25(9):1792-802.
  51. Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice.
    Authors: Pillai V, Bindu S, Sharp W, Fang Y, Kim G, Gupta M, Samant S, Gupta M
    Am J Physiol Heart Circ Physiol, 2016-02-12;310(8):H962-72.
  52. An Essential Role of NRF2 in Diabetic Wound Healing.
    Authors: Long M, Rojo de la Vega M, Wen Q, Bharara M, Jiang T, Zhang R, Zhou S, Wong P, Wondrak G, Zheng H, Zhang D
    Diabetes, 2015-12-30;65(3):780-93.
  53. hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway.
    Authors: Paquet N, Adams M, Leong V, Ashton N, Touma C, Gamsjaeger R, Cubeddu L, Beard S, Burgess J, Bolderson E, O'Byrne K, Richard D
    Nucleic Acids Res, 2015-08-10;43(18):8817-29.
  54. Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities.
    Authors: Chen Y, Harris R, Hatahet Z, Chou K
    Proc Natl Acad Sci U S A, 2015-08-03;112(33):E4556-64.
  55. Improved neurological outcome by intramuscular injection of human amniotic fluid derived stem cells in a muscle denervation model.
    Authors: Chen C, Cheng F, Su H, Sheu M, Lu Z, Chiang C, Yang D, Sheehan J, Pan H
    PLoS ONE, 2015-05-06;10(5):e0124624.
    Species: Rat
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: IHC, Western Blot
  56. Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde.
    Authors: Long M, Tao S, Rojo de la Vega M, Jiang T, Wen Q, Park S, Zhang D, Wondrak G
    Cancer Prev Res (Phila), 2015-02-23;8(5):444-54.
  57. Atg7 Overcomes Senescence and Promotes Growth of BrafV600E-Driven Melanoma.
    Authors: Xie X, Koh J, Price S, White E, Mehnert J
    Cancer Discov, 2015-02-11;5(4):410-23.
  58. Nicotinamide enhances repair of arsenic and ultraviolet radiation-induced DNA damage in HaCaT keratinocytes and ex vivo human skin.
    Authors: Thompson B, Halliday G, Damian D
    PLoS ONE, 2015-02-06;10(2):e0117491.
  59. DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair.
    Authors: Abdou I, Poirier G, Hendzel M, Weinfeld M
    Nucleic Acids Res, 2014-12-24;43(2):875-92.
  60. Radiation-Induced Impairment in Lung Lymphatic Vasculature
    Authors: Ye Cui, Julie Wilder, Cecilia Rietz, Andrew Gigliotti, Xiaomeng Tang, Yuanyuan Shi et al.
    Lymphatic Research and Biology
  61. Oncogenic KRAS confers chemoresistance by upregulating NRF2.
    Authors: Tao S, Wang S, Moghaddam S, Ooi A, Chapman E, Wong P, Zhang D
    Cancer Res, 2014-10-22;74(24):7430-41.
  62. Diabetes-induced oxidative DNA damage alters p53-p21CIP1/Waf1 signaling in the rat testis.
    Authors: Kilarkaje N, Al-Bader M
    Reprod Sci, 2014-05-14;22(1):102-12.
  63. Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis.
    Authors: Wu T, Zhao F, Gao B, Tan C, Yagishita N, Nakajima T, Wong P, Chapman E, Fang D, Zhang D
    Genes Dev, 2014-03-17;28(7):708-22.
  64. Mitochondrial oxidative stress-induced epigenetic modifications in pancreatic epithelial cells.
    Authors: Mishra P, Raghuram G, Jain D, Jain S, Khare N, Pathak N
    Int J Toxicol, 2014-02-20;33(2):116-29.
  65. Hydroquinone increases 5-hydroxymethylcytosine formation through ten eleven translocation 1 (TET1) 5-methylcytosine dioxygenase.
    Authors: Coulter J, O'Driscoll C, Bressler J
    J Biol Chem, 2013-08-12;288(40):28792-800.
  66. Omega-3 polyunsaturated fatty acids selectively inhibit growth in neoplastic oral keratinocytes by differentially activating ERK1/2.
    Authors: Nikolakopoulou Z, Nteliopoulos G, Michael-Titus A, Parkinson E
    Carcinogenesis, 2013-07-26;34(12):2716-25.
  67. Progression of genotype-specific oral cancer leads to senescence of cancer-associated fibroblasts and is mediated by oxidative stress and TGF-beta.
    Authors: Hassona Y, Cirillo N, Lim K, Herman A, Mellone M, Thomas G, Pitiyage G, Parkinson E, Prime S
    Carcinogenesis, 2013-01-27;34(6):1286-95.
  68. Nicotinamide enhances repair of ultraviolet radiation-induced DNA damage in human keratinocytes and ex vivo skin.
    Authors: Surjana D, Halliday G, Damian D
    Carcinogenesis, 2013-01-24;34(5):1144-9.
  69. Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc.
    Authors: Bock F, Shahzad K, Wang H, Stoyanov S, Wolter J, Dong W, Pelicci P, Kashif M, Ranjan S, Schmidt S, Ritzel R, Schwenger V, Reymann K, Esmon C, Madhusudhan T, Nawroth P, Isermann B
    Proc Natl Acad Sci U S A, 2012-12-24;110(2):648-53.
  70. Oxidative damage increases and antioxidant gene expression decreases with aging in the mouse ovary.
    Authors: Lim J, Luderer U
    Biol. Reprod., 2010-12-08;84(4):775-82.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  71. The interaction of aging and oxidative stress contributes to pathogenesis in mouse and human Huntington disease neurons
    Authors: Machiela E, Jeloka R, Caron NS et al.
    Front Aging Neurosci

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8-oxo-dG Antibody
By Anonymous on 01/03/2022
Application: IHC Sample Tested: Stomach tissue Species: Mouse
Immunohistochemistry 8-oxo-dG Antibody 4354-MC-050
8-oxo-dG Antibody
By Anonymous on 10/28/2021
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Lung tissue Species: Mouse

Blue- DAPI; Green:8-oxo-dG

Immunocytochemistry/Immunofluorescence 8-oxo-dG Antibody 4354-MC-050
8-oxo-dG Antibody
By Anonymous on 08/11/2021
Application: IHC Sample Tested: prostate carcinoma Species: Human
Immunohistochemistry 8-oxo-dG Antibody 4354-MC-050
8-oxo-dG Antibody
By Anonymous on 12/28/2017
Application: IHC Sample Tested: Skin tissue Species: Human
Immunohistochemistry 8-oxo-dG Antibody 4354-MC-050