Nogo-C: Products

Nogo-C is the smallest isoform of Nogo, a member of the reticulon family of transmembrane proteins. This family is characterized by the presence of a nonsignal sequence- containing N-terminus, a topologically conserved 200 amino acid C-terminus that contains two transmembrane domains, and an ER-retention motif. It has punctate intracellular distribution within the ER that is reminescent of a reticulum.