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LRIG3: Products
LRIG3 is a type I transmembrane glycoprotein that belongs to the LRIG gene family. It has a large extracellular domain (ECD) that contains 17 LRRs and three C2-type Ig-like domains. These two domain types on LRIG1 may participate in EGF R binding. At least two alternate splice forms exist. LRIG3 is found on both intra- and extracellular membranes. Human LRIG3 ECD is 91% and 95% aa identical to the ECDs of mouse and bovine LRIG3, respectively.
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