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Selective fatty acid desaturase 2 inhibitor
Cell permeable inhibitor of SREBP activation
Diacylglycerol lipase inhibitor
Selective non-lipid inhibitor of sphingosine kinase
Potent fatty acid synthase inhibitor; proapoptotic
Competitive inhibitor of SREBP site 1 protease
2,3-Oxidosqualene cyclase (OSC) inhibitor; blocks cholesterol synthesis
Inhibitor of phosphatidylcholine transfer protein (PC-TP)
Potent acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor
Potent human fatty acid synthase (hFASN) inhibitor
Potent and reversible fatty acid desaturase 1 inhibitor; orally bioavailable
Potent microsomal triglyceride transfer protein (MTP) inhibitor