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Pep 2-8

Catalog #: 6423 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6423/1
Pep 2-8
1 Image
Description: Potent PCSK9 inhibitor

Purity: ≥95%

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Biological Activity

Pep 2-8 is a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.

Technical Data

M.Wt:
1715.88
Formula:
C83H110N16O24
Sequence:
TVFTSWEEYLDWV

(Modifications: Thr-1 = N-terminal Ac, Val-13 = C-terminal amide)

Solubility:
Soluble to 2 mg/ml in PBS (pH 7.4)
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
1541011-97-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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