o-3M3FBS
Chemical Name: 2,4,6-Trimethyl-N-[2-(trifluoromethyl)phenyl]benzenesulfonamide
Purity: ≥99%
Biological Activity
o-3M3FBS is an inactive analog of m-3M3FBS. Used as a negative control.Active Analog also available.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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The Complement System Component C5a Produces Thermal Hyperalgesia via Macrophage-to-Nociceptor Signaling That Requires NGF and TRPV1
J Neurosci, 2016;36(18):5055-70. -
Identification of a compound that directly stimulates phospholipase C activity.
Bae et al.
Mol.Pharmacol., 2003;63:1043
Product Datasheets
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Citations for o-3M3FBS
The citations listed below are publications that use Tocris products. Selected citations for o-3M3FBS include:
6 Citations: Showing 1 - 6
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IPIP27 Coordinates PtdIns(4,5)P2 Homeostasis for Successful Cytokinesis.
Authors: Carim Et al.
Curr Biol 2019;29:775
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Activation of phospholipase C mimics the phase shifting effects of light on melatonin rhythms in retinal photoreceptors.
Authors: Semple-Rowland Et al.
PLoS One 2014;8:e83378
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Increases in intracellular calcium via activation of potentially multiple phospholipase C isozymes in mouse olfactory neurons.
Authors: Szebenyi Et al.
Front Cell Neurosci 2014;8:336
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Diacylglycerol mediates regulation of TASK potassium channels by Gq-coupled receptors.
Authors: Wilke Et al.
Nat Commun 2014;5:5540
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Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current.
Authors: Horowitz Et al.
PLoS One 2005;126:243
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Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation.
Authors: Krjukova Et al.
Br J Pharmacol 2004;143:3
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