Mouse/Rat Neuropilin-1 APC-conjugated Antibody Summary
Phe22-Ala810 (Lys811Arg), Ser829-Asp854
Accession # Q9QWJ9
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of Neuropilin‑1 in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Goat Anti-Mouse/Rat Neuropilin-1 APC-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB566A, filled histogram) or isotype control antibody (Catalog # IC108A, open histogram). View our protocol for Staining Membrane-associated Proteins.
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Detection of Neuropilin‑1 in PC‑12 Rat Cell Line by Flow Cytometry. PC-12 rat adrenal pheochromocytoma cell line was stained with Goat Anti-Mouse/Rat Neuropilin-1 APC-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB566A, filled histogram) or isotype control antibody (Catalog # IC108A, open histogram). View our protocol for Staining Membrane-associated Proteins.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Neuropilin-1
Neuropilin-1 is a type I transmembrane protein that is expressed in the developing nervous system and by endothelial and tumor cells. Neuropilin-1 binds members of the class III secreted semaphorin subfamily as well as some isoforms of VEGF family proteins. The amino acid sequence of rat Neuropilin-1 extracellular domain is 98% and 93% identical to that of mouse and human Neuropilin-1, respectively.
Product Datasheets
Product Specific Notices
* This product or the use of this product is covered by U.S. Patents owned by The Regents of the University of California. This product is for research use only and is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic, therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for such purposes, contact The Regents of the University of California.
U.S. Patent # 6,054,293, 6,623,738, and other U.S. and international patents pending.
Citations for Mouse/Rat Neuropilin-1 APC-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Neuropilin-1 cooperates with PD-1 in CD8+ T cells predicting outcomes in melanoma patients treated with anti-PD1
Authors: Julien Rossignol, Zakia Belaid, Guillemette Fouquet, Flavia Guillem, Rachel Rignault, Pierre Milpied et al.
iScience
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A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells
Authors: Frédéric Van Gool, Michelle L.T. Nguyen, Maxwell R. Mumbach, Ansuman T. Satpathy, Wendy L. Rosenthal, Simone Giacometti et al.
Immunity
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Neuropilin-1 Mediated Arterial Differentiation of Murine Pluripotent Stem Cells
Authors: D Kim, V Lee, T Dorsey, L Niklason, L Gui, G Dai
Stem Cells Dev., 2018-03-13;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Regulation of Effector Treg Cells in Murine Lupus
Authors: Uma Chandrasekaran, Woelsung Yi, Sanjay Gupta, Chien-Huan Weng, Eugenia Giannopoulou, Yurii Chinenov et al.
Arthritis & Rheumatology
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FOXP3+ Tregs require WASP to restrain Th2-mediated food allergy
J Clin Invest, 2016-09-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation
Authors: Agnieszka M Kabat, Oliver J Harrison, Thomas Riffelmacher, Amin E Moghaddam, Claire F Pearson, Adam Laing et al.
eLife
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CD137 Agonist Therapy Can Reprogram Regulatory T Cells into Cytotoxic CD4+ T Cells with Antitumor Activity
Authors: Ilseyar Akhmetzyanova, Gennadiy Zelinskyy, Elisabeth Littwitz-Salomon, Anna Malyshkina, Kirsten K. Dietze, Hendrik Streeck et al.
The Journal of Immunology
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An increase in tolerogenic dendritic cell and natural regulatory T cell numbers during experimental autoimmune encephalomyelitis in Rras-/- mice results in attenuated disease.
Authors: Ray A, Basu S, Miller N, Chan A, Dittel B
J Immunol, 2014-04-25;192(11):5109-17.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Identifying Gut Microbe–Host Phenotype Relationships Using Combinatorial Communities in Gnotobiotic Mice
Authors: Jeremiah J. Faith, Philip P. Ahern, Vanessa K. Ridaura, Jiye Cheng, Jeffrey I. Gordon
Science Translational Medicine
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IL-2–Independent and TNF-alpha –Dependent Expansion of V beta 5+ Natural Regulatory T Cells during Retrovirus Infection
Authors: Lara Myers, Jara J. Joedicke, Aaron B. Carmody, Ronald J. Messer, George Kassiotis, Jaquelin P. Dudley et al.
The Journal of Immunology
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Endothelial-specific expression of WNK1 kinase is essential for angiogenesis and heart development in mice.
Authors: Xie J, Wu T, Xu K, Huang IK, Cleaver O, Huang CL
Am. J. Pathol., 2009-07-30;175(3):1315-27.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr
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