Mouse IL-31 Biotinylated Antibody

Catalog # Availability Size / Price Qty
BAF3028
Product Details
Citations (1)
FAQs
Supplemental Products
Reviews (1)

Mouse IL-31 Biotinylated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse IL-31 in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human IL-31 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant mouse IL-31
Thr24-Cys163
Accession # Q6EAL8
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Label
Biotin

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse IL‑31

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IL-31

IL-31 is a 25 kDa, unique member of the short chain group of alpha -helical cytokines. It is produced by activated T cells, particularly the Th2 CD4+ phenotype. Mouse IL‑31 cDNA encodes a 163 amino acid (aa) precursor that contains a 22 aa signal sequence and a 141 aa mature region. IL-31 signals through a receptor complex composed of IL-31 receptor A and Oncostatin M receptor. Mature mouse IL‑31 shares 25% aa sequence identity with mature human IL-31 and 44% aa sequence identity with a rat IL-31-like protein.

Long Name
Interleukin 31
Entrez Gene IDs
386653 (Human); 76399 (Mouse)
Alternate Names
IL31; IL-31; IL-31interleukin-31; interleukin 31

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Citation for Mouse IL-31 Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. IL-31 is crucial for induction of pruritus, but not inflammation, in contact hypersensitivity
    Authors: A Takamori, A Nambu, K Sato, S Yamaguchi, K Matsuda, T Numata, T Sugawara, T Yoshizaki, K Arae, H Morita, K Matsumoto, K Sudo, K Okumura, J Kitaura, H Matsuda, S Nakae
    Sci Rep, 2018-04-27;8(1):6639.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC

FAQs

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Reviews for Mouse IL-31 Biotinylated Antibody

Average Rating: 5 (Based on 1 Review)

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Mouse IL-31 Biotinylated Antibody
By Katie Myers on 11/14/2022
Application: ELISA Sample Tested: Serum Species: Mouse

This was a fairly sensitive detection antibody. It worked well in our Mouse Assay.