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ML 382

Catalog #: 5738 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5738/10
5738/50
ML 382 | CAS No. 1646499-97-9 | Mas-Related G Protein Coupled Receptor Modulators
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Description: MRGPRX1 positive allosteric modulator

Chemical Name: 2-[(Cyclopropylsulfonyl)amino]-N-(2-ethoxyphenyl)benzamide

Purity: ≥98%

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Biological Activity

ML 382 is a selective MRGPRX1 positive allosteric modulator (EC50 = 190 nM). Exhibits selectivity for MrgX1 over MrgX2, MrgC11 and a panel of 68 other GPCRs, ion channels and transporters. Enhances BAM (8-22) potency at MRGPRX1 by 7-fold.

Technical Data

M.Wt:
360.43
Formula:
C18H20N2O4S
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol with gentle warming
Purity:
≥98%
Storage:
Store at RT
CAS No:
1646499-97-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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