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Human TL1A/TNFSF15 Antibody

Catalog #: MAB7441
3 Citations 2 Reviews Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
MAB7441
MAB7441-SP
Product Details
Citations (3)
FAQs
Supplemental Products
Reviews (2)
Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human TL1A/TNFSF15 Antibody Summary

Species Reactivity
Human
Specificity
Detects recombinant human TL1A in Western Blot and Neutralization
Source
Monoclonal Rat IgG1 Clone # 293327
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant mouse TL1A/TNFSF15
Ile94-Leu270
Accession # NP_796345.3
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details.
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human TL1A/TNFSF15 (Catalog # 1319-TL)

Neutralization
Reichwald, K. et al. (2014) PLoS ONE. 9:e85793.
Reichwald, K. et al. (2014) PLoS ONE. 9:e105627.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TL1A/TNFSF15

TL1A is a type II transmembrane protein belonging to the TNF superfamily and has been designated TNFSF15. It is expressed predominantly in endothelial cells, and its expression is inducible by TNF-alpha and IL-1 alpha. TL1A binds with high affinity to DR3/TNFRSF25 on activated T cells.

Long Name
TNF-like 1
Entrez Gene IDs
9966 (Human); 326623 (Mouse)
Alternate Names
MGC129934; MGC129935; TL1A; TL1Vascular endothelial cell growth inhibitor; TNF superfamily ligand TL1A; TNFSF15; tumor necrosis factor (ligand) superfamily, member 15; tumor necrosis factor ligand superfamily member 15; vascular endothelial growth inhibitor-192A; VEGI; VEGI192A; VEGITNF ligand-related molecule 1

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Citations for Human TL1A/TNFSF15 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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  1. The TL1A-DR3 Axis Selectively Drives Effector Functions in Human MAIT Cells
    Authors: A Sattler, LG Thiel, AH Ruhm, N Souidi, M Seifert, G Herberth, K Kotsch
    J. Immunol., 2019-10-18;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  2. ROR?-expressing T regulatory cells restrain allergic skin inflammation
    Authors: N Malhotra, JM Leyva-Cast, U Jadhav, O Barreiro, C Kam, NK O'Neill, F Meylan, P Chambon, UH von Andria, RM Siegel, EC Wang, R Shivdasani, RS Geha
    Sci Immunol, 2018-03-02;3(21):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  3. TL1A induces TCR independent IL-6 and TNF-alpha production and growth of PLZF(+) leukocytes.
    Authors: Reichwald K, Jorgensen T, Tougaard P, Skov S
    PLoS ONE, 2014-01-08;9(1):e85793.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization

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Reviews for Human TL1A/TNFSF15 Antibody

Average Rating: 3.5 (Based on 2 Reviews)

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Human/Mouse TL1A/TNFSF15 Antibody
By Anonymous on 11/15/2017
Application: ELISA Sample Tested: HEK293 human embryonic kidney cell line Species: Human
ELISA Human/Mouse TL1A/TNFSF15 Antibody MAB7441
Human/Mouse TL1A/TNFSF15 Antibody
By Anonymous on 07/17/2017
Application: WB Sample Tested: Recombinant protein Species: Human

Use for detection of TL1A in a sandwich ELISA (2.5ug/mL concentration), and for detection of recombinant TL1A in Western blots at a 1:1000 dilution, followed by a Licor secondary antibody.

Western Blot Human/Mouse TL1A/TNFSF15 Antibody MAB7441