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Human SOX17 NorthernLights™ NL557-conjugated Antibody

Catalog #: NL1924R
15 Citations Datasheet / COA / SDS
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NL1924R
Product Details
Citations (15)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human SOX17 NorthernLights™ NL557-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human SOX17 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) SOX2, rhSOX6, and rhSOX15 is observed.
Source
Polyclonal Goat IgG
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
NL557 (Excitation= 557 nm, Emission= 574 nm)

Applications

Recommended Concentration
Sample
Immunocytochemistry
Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: SOX17

SOX17 is a member of the SOX family of transcription factors that bind DNA via a high mobility group (HMG) domain. SOX17 is suggested to play an important role in endoderm development (1, 2). In Western blot, AF1924 detects a 60 kDa band of endogenous SOX17 which is higher than predicted molecular weight but consistent with the current literature (3).

 

References
  1. Kanai-Azuma, M. et al. (2002) Development 129:2367.
  2. Katoh, M. et al. (2002) Int. J. Mol. Med. 9:153.
  3. Sohn, J. et al. (2006) J. Neuroscience 26:9722.
Long Name
Transcription Factor SOX17
Entrez Gene IDs
64321 (Human)
Alternate Names
FLJ22252; SOX17; SRY (sex determining region Y)-box 17; SRY-related HMG-box transcription factor SOX17; transcription factor SOX-17; VUR3

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Citations for Human SOX17 NorthernLights™ NL557-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

15 Citations: Showing 1 - 10
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  1. Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism
    Authors: Collin de l'Hortet A, Takeishi K, Guzman-Lepe J et al.
    Cell Metab.
  2. Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells
    Authors: K Takeishi, A Collin de, Y Wang, K Handa, J Guzman-Lep, K Matsubara, K Morita, S Jang, N Haep, RM Florentino, F Yuan, K Fukumitsu, K Tobita, W Sun, J Franks, ER Delgado, EM Shapiro, NA Fraunhoffe, AW Duncan, H Yagi, T Mashimo, IJ Fox, A Soto-Gutie
    Cell Rep, 2020-06-02;31(9):107711.
  3. Biofabrication of synthetic human liver tissue with advanced programmable functions
    Authors: Rodrigo M. Florentino, Kazutoyo Morita, Nils Haep, Takashi Motomura, Ricardo Diaz-Aragon, Lanuza A.P. Faccioli et al.
    iScience
  4. Derivation and characterization of the induced pluripotent stem cell line CUIMCi004-A from a patient with a novel frameshift variant in exon 18a of OCRL
    Authors: G Iannello, A Patel, D Sirabella, B Corneo, VV Thaker
    Stem Cell Research, 2021-12-23;59(0):102635.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  5. Generation of the iPSC line CUIMCi003-A derived from a patient with severe early onset obesity
    Authors: G Iannello, A Patel, D Sirabella, B Corneo, V Thaker
    Stem Cell Research, 2021-06-21;54(0):102432.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  6. Generation of an induced pluripotent stem cell line (FRIMOi007-A) derived from an incomplete achromatopsia patient carrying a novel homozygous mutation in PDE6C gene
    Authors: J Domingo-Pr, V Abad-Moral, M Riera, R Navarro, B Corcostegu, E Pomares
    Stem Cell Res, 2019-09-04;40(0):101569.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  7. Generation of Best disease-derived induced pluripotent stem cell line (FRIMOi006-A) carrying a novel dominant mutation in BEST1 gene
    Authors: J Domingo-Pr, M Riera, V Abad-Moral, S Ruiz-Nogal, B Corcostegu, E Pomares
    Stem Cell Res, 2019-09-04;40(0):101570.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  8. Establishment of an induced pluripotent stem cell line (FRIMOi005-A) derived from a retinitis pigmentosa patient carrying a dominant mutation in RHO gene
    Authors: J Domingo-Pr, M Riera, A Burés-Jels, B Corcostegu, E Pomares
    Stem Cell Res, 2019-05-22;38(0):101468.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  9. Generation of two iPS cell lines (FRIMOi003-A and FRIMOi004-A) derived from Stargardt patients carrying ABCA4 compound heterozygous mutations
    Authors: M Riera, A Patel, A Burés-Jels, B Corcostegu, S Chang, E Pomares, B Corneo, JR Sparrow
    Stem Cell Res, 2019-02-13;36(0):101389.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  10. No evidence of involvement of E-cadherin in cell fate specification or the segregation of Epi and PrE in mouse blastocysts
    Authors: K Filimonow, N Saiz, A Suwi?ska, T Wyszomirsk, JB Grabarek, E Ferretti, A Piliszek, B Plusa, M Maleszewsk
    PLoS ONE, 2019-02-08;14(2):e0212109.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  11. Generation of an induced pluripotent stem cell line (FRIMOi002-A) from a retinitis pigmentosa patient carrying compound heterozygous mutations in USH2A gene
    Authors: M Riera, A Patel, B Corcostegu, S Chang, B Corneo, JR Sparrow, E Pomares
    Stem Cell Res, 2019-01-17;35(0):101386.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  12. Establishment and characterization of an iPSC line (FRIMOi001-A) derived from a retinitis pigmentosa patient carrying PDE6A mutations
    Authors: M Riera, A Patel, B Corcostegu, S Chang, JR Sparrow, E Pomares, B Corneo
    Stem Cell Res, 2019-01-17;35(0):101385.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  13. Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration
    Authors: JS Saini, B Corneo, JD Miller, TR Kiehl, Q Wang, NC Boles, TA Blenkinsop, JH Stern, S Temple
    Cell Stem Cell, 2017-01-26;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  14. CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development
    Authors: Kun Zhang, Jocelyn M. Haversat, Jesse Mager
    Developmental Biology
  15. Oct4 kinetics predict cell lineage patterning in the early mammalian embryo.
    Authors: Plachta N, Bollenbach T, Pease S
    Nat. Cell Biol., 2011-01-23;13(2):117-23.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr

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