Human RXR gamma /NR2B3 Antibody

Catalog #: PP-H3210-00 Datasheet / COA / SDS

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PP-H3210-00

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human RXR gamma /NR2B3 Antibody Summary

Species Reactivity

Human

Specificity

This antibody specifically recognizes human RXR gamma and does not cross-react with human RXR alpha or human RXR beta. Not yet tested in other species.

Source

Monoclonal Mouse IgG_2A Clone # H3210

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Recombinant human RXR gamma/NR2B3
aa 2-137

Formulation

A liquid formulation in physiologic saline with 0.1% NaN₃.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

This antibody can be used at 1 μg/mL under reducingconditions and at 3 μg/mL under non-reducing conditions with the appropriatesecondary reagents to detect human RXR gamma.

Immunoprecipitation

This antibody can be used at 0.3 μg/mL with the appropriatesecondary reagents to detect human RXR gamma.

Direct ELISA

This antibody can be used at 0.3 μg/mL with the appropriatesecondary reagents to detect human RXR gamma.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Background: RXR gamma/NR2B3

Retinoid X Receptor gamma (RXR gamma ; NR2B3) is a member of the Orphan Nuclear Receptor superfamily. 9-cis retinoic acid can bind to RXR. RXR gamma is expressed in the brain and pituitary. Along with other members of the RXR family, RXR gamma plays roles in a variety of processes including embryonic patterning and organogenesis, cell proliferation and cell differentiation. RXRs commonly function as heterodimers with other members of the Nuclear Receptor superfamily. Two N-terminally different isoforms of RXR gamma with different expression patterns exist, RXR gamma 1 and RXR gamma 2.

Long Name

Retinoid X Receptor, gamma

Entrez Gene IDs

6258 (Human)

Alternate Names

NR2B3; NR2B3retinoid X receptor-gamma; Nuclear receptor subfamily 2 group B member 3; retinoic acid receptor RXR-gamma; Retinoid X receptor gamma; retinoid X receptor, gamma; RXR gamma; RXRC; RXRG