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Human RAR beta /NR1B2 Antibody

Catalog #: PP-H4338-00
1 Citation Datasheet / COA / SDS
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PP-H4338-00
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Citations (1)
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Human RAR beta /NR1B2 Antibody Summary

Species Reactivity
Human
Specificity
This antibody specifically recognizes human RAR beta and does not cross-react with human RAR alpha or RAR gamma. Not yet tested in other species.
Source
Monoclonal Mouse IgG2A Clone # H4338
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Recombinant human RAR beta/NR1B2
aa 2-79
Formulation
A liquid formulation in physiologic saline with 0.1% NaN3.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
This antibody can be used at 1 μg/mL under reducingconditions with the appropriate secondary reagents to detect human RAR beta.
 
Immunoprecipitation
Optimal dilutions should be determined by eachlaboratory.
 
Direct ELISA
This antibody can be used at 0.2 μg/mL with the appropriatesecondary reagents to detect human RAR beta.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Background: RAR beta/NR1B2

Retinoic Acid Receptor beta (RAR beta, hap; NR1B2) is closely related to the Thyroid hormone Receptor (TR). RARs bind to two retinoids, all-trans retinoic acid and 9-cis retinoic acid. RAR beta is expressed in the ovary, uterus, mammary cell lines, and adult and fetal spleen. RARs have been associated with several diseases, among which cancer is one of the most important. RAR beta takes part in apoptosis.

Long Name
Retinoic Acid Receptor, beta
Entrez Gene IDs
5915 (Human)
Alternate Names
beta polypeptide; HAP; HBV-activated protein; NR1B2; RAR beta; RARB; retinoic acid receptor, beta; RRB2

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Citation for Human RAR beta /NR1B2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. RAR?/RXR Synergism Potentiates Retinoid Responsiveness in Cutaneous T Cell Lymphoma Cell Lines
    Authors: L Wang, SS DeMarco, MS Peaks, AL Maiorana-B, J Chen, MJ Crouch, BM Shewchuk, SR Shaikh, CM Phillips, LC Bridges
    Exp. Dermatol., 2017-07-03;0(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot

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