Human PTP beta / zeta /PTPRZ Antibody Summary
Gly302-Asn754
Accession # P23471
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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PTP beta / zeta /PTPRZ in Human Brain. PTP beta /zeta/PTPRZ was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using Rat Anti-Human PTP beta /zeta/PTPRZ Monoclonal Antibody (Catalog # MAB26881) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS017) and counterstained with hematoxylin (blue). Specific staining was localized to neuronal cell bodies. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: PTP beta/zeta/PTPRZ
PTPRZ, also known as Protein tyrosine phosphatase beta/zeta (PTP beta / zeta ), is a member of the receptor-type protein-tyrosine phosphatase family. This phosphatase is involved in the regulation of specific developmental processes in the central nervous system. A protein of 2,307 amino acids, PTPRZ is membrane-spanning with two cytoplasmic protein tyrosine phosphatase domains and an extracellular domain.
Product Datasheets
Citations for Human PTP beta / zeta /PTPRZ Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 2
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Reduced length of nodes of Ranvier and altered proteoglycan immunoreactivity in prefrontal white matter in major depressive disorder and chronically stressed rats
Authors: José Javier Miguel-Hidalgo, Erik Hearn, Mohadetheh Moulana, Khunsa Saleem, Austin Clark, Maggie Holmes et al.
Sci Rep
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Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth
Authors: Y Shi, YF Ping, W Zhou, ZC He, C Chen, BS Bian, L Zhang, L Chen, X Lan, XC Zhang, K Zhou, Q Liu, H Long, TW Fu, XN Zhang, MF Cao, Z Huang, X Fang, X Wang, H Feng, XH Yao, SC Yu, YH Cui, X Zhang, JN Rich, S Bao, XW Bian
Nat Commun, 2017-06-01;8(0):15080.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry, Functional Assay
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