Human/Mouse TSG-6 Antibody Summary
Trp18-Leu277
Accession # P98066
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: TSG-6
TSG-6 is a secreted hyaluronan-binding protein composed of a link domain and Cub domain. It is induced in many cell types by inflammatory mediators. Via its link domain, TSG-6 is a potent inhibitor of polymorphonuclear leukocyte migration. TSG-6 forms a stable complex with the serine protease inhibitor Inter-alpha -Inhibitor (I alpha I) and potentiates the anti-plasmin activity of I alpha I.
Product Datasheets
Citations for Human/Mouse TSG-6 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 5
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Prostaglandin E2 Indicates Therapeutic Efficacy Of Mesenchymal Stem Cells In Experimental Traumatic Brain Injury
Authors: DJ Kota, KS Prabhakara, N Toledano-F, D Bhattarai, Q Chen, B DiCarlo, P Smith, F Triolo, PL Wenzel, CS Cox, SD Olson
Stem Cells, 2017-03-16;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
TNF?-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury
Proc. Natl. Acad. Sci. U.S.A., 2016-11-28;113(50):E8151-E8158.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
Endogenous mesenchymal stromal cells in bone marrow are required to preserve muscle function in mdx mice.
Authors: Fujita R, Tamai K, Aikawa E, Nimura K, Ishino S, Kikuchi Y, Kaneda Y
Stem Cells, 2015-03-01;33(3):962-75.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Constitutive expression of inter-alpha-inhibitor (IalphaI) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex.
Authors: Zhang S, He H, Day AJ, Tseng SC
J. Biol. Chem., 2012-02-20;287(15):12433-44.
Species: Human
Sample Types: Tissue Homogenates, Whole Tissue
Applications: IHC-Fr, Western Blot -
Biochemical characterization and function of complexes formed by hyaluronan and the heavy chains of inter-alpha-inhibitor (HC*HA) purified from extracts of human amniotic membrane.
Authors: He H, Li W, Tseng DY, Zhang S, Chen SY, Day AJ, Tseng SC
J. Biol. Chem., 2009-06-02;284(30):20136-46.
Species: Human
Sample Types: Tissue Homogenates
Applications: Western Blot
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Average Rating: 4.1 (Based on 8 Reviews)
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this antibody was detected in the mouse cortex at different timepoint. It works very good with very clear band.
Western Blot with diff concentration
