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Human/Mouse/Rat Olig2 Antibody

Catalog #: AF2418
190 Citations 4 Reviews Datasheet / COA / SDS
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AF2418
AF2418-SP
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Olig2 and Oligodendrocyte Marker O4 in Rat Cortical Stem Cells.
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Citations (190)
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Human/Mouse/Rat Olig2 Antibody Summary

Species Reactivity
Human, Mouse, Rat
Specificity
Detects human Olig2 in direct ELISAs and Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human Olig2
Met1-Lys323
Accession # Q13516
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details.
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human Olig2
Immunohistochemistry
5-15 µg/mL
See below
Chromatin Immunoprecipitation (ChIP)
5 µg/5 x 106 cells
See below
Dual RNAscope ISH-IHC
5-15 µg/mL
Immersion fixed paraffin-embedded sections of human cortex
Immunocytochemistry
5-15 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunocytochemistry Olig2 and Oligodendrocyte Marker O4 antibody in Rat Cortical Stem Cells by Immunocytochemistry (ICC). View Larger

Olig2 and Oligodendrocyte Marker O4 in Rat Cortical Stem Cells. Olig2 and Oligodendrocyte Marker O4 were detected in 7 day differentiated rat cortical stem cells using 10 µg/mL Goat Anti-Human/Mouse/Rat Olig2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2418) and 10 µg/mL Goat Anti-Human/Mouse/Rat/Chicken O4 Monoclonal Antibody (Catalog # MAB1326). Cells were incubated with primary antibodies for 3 hours at room temperature. Cells were stained for Olig2 using the NorthernLights™ 637-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL002), and stained for O4 using an anti-mouse IgM secondary antibody (pseudo-stained green). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Chromatin Immunoprecipitation (ChIP) Detection of Olig2-regulated Genes antibody by Chromatin Immunoprecipitation. View Larger

Detection of Olig2-regulated Genes by Chromatin Immunoprecipitation. A172 human glioblastoma cell line were fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. Olig2/DNA complexes were immunoprecipitated using 5 µg Goat Anti-Human/Mouse/Rat Olig2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2418) or control antibody (Catalog # AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (Catalog # BAF109). Immunocomplexes were captured using 50 µL of MagCellect Streptavidin Ferrofluid (Catalog # MAG999) and DNA was purified using chelating resin solution. Thep21promoter was detected by standard PCR.

Immunohistochemistry Olig2 antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr). View Larger

Olig2 in Mouse Embryo. Olig2 was detected in immersion fixed frozen sections of mouse embryo (13 d.p.c.) using Goat Anti-Human/Mouse/Rat Olig2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2418) at 8 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to developing brain. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Immunohistochemistry View Larger

Olig2 in Human Brain. Olig2 was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using Goat Anti-Human/Mouse/Rat Olig2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2418) at 10 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell nuclei. Staining was performed using our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Immunohistochemistry View Larger

Olig2 in Rat Midbrain. Olig2 was detected in immersion fixed paraffin-embedded sections of rat midbrain using Goat Anti-Human/Mouse/Rat Olig2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2418) at 10 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell nuclei. Staining was performed using our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Immunocytochemistry/ Immunofluorescence Detection of Mouse Olig2 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse Olig2 by Immunocytochemistry/Immunofluorescence Pathological analysis of l2hgdh-/- mice.The figure compares the histological and ultrastructural appearance of the brain of l2hgdh+/+ (left panels: A, B, E, G, H, K, L) and l2hgdh-/- mice (right panels: C, D, F, I, J, M, N). Hematoxylin and eosin staining shows low-magnification of the lateral part of the brain (A, C) at the level of the lateral ventricle (LV), the caudate putamen (striatum; CPu) and the anterior commissure, anterior part (aca). Higher magnification of pencils of Wilson are shown in panels B and D. Notice the satellite oligodendrocyte at B (arrow). Luxol fast blue staining of myelin is shown in E and F, highlighting the predominant presence of vacuoles in the pencils of Wilson of the striatum of the l2hgdh-/- mouse. Panels G-J are microphotographs from the junction between cortex and white matter in the vicinity of corpus callosum. Immunostaining of NeuN (G and I) shows that most vacuoles in the l2hgdh-/- mice are at distance from the nucleus of neurons (notice the abundance of vacuoles in the lower part of panel I, devoid of neurons) although a few vacuoles indent the nucleus of some neurons (arrowheads). However, the nucleus of satellite oligodendrocytes is also present in close contact to the vacuole indenting the nucleus of some neurons (arrows), preventing to identify clearly which cell type actually contains the peri-neuronal vacuole. In contrast, immunostaining of Olig2 (H and J) clearly shows that most vacuoles are in close contact to the nucleus of oligodendrocytes in the l2hgdh-/- mouse brain. Notice the small size of the nucleus of oligodendrocytes compared to the nucleus of neurons. Panels K-N are Transmission Electron Microscopy photographs of striatum tissue. Ultrastructural analysis (K-N) shows many empty-looking cell processes (asterisks in panels M and N), containing dilated cytoplasmic organelles, in the glia of l2hgdh-/- mice. The myelin sheath of many axons appears focally altered or disrupted (arrows at M and N), sometimes at the vicinity of empty-looking spaces. C, capillary lumen. The length of the scale bar is indicated in each panel. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25763823), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Rat Olig2 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Rat Olig2 by Immunocytochemistry/Immunofluorescence alpha -Syn PFF exposure to immature OLGs during differentiation-induced abnormal oligodendrogenesis. a Confocal images of oligodendroglial cells on day 4 after differentiation induction showing the colocalization of alpha -syn immunoreactivity and cleaved caspase-9 expression. The cells were incubated with 1 μM alpha -syn PFFs for 24 h (day 3–4) before fixation. White arrowheads indicate intracellular inclusions. The regions marked by dotted squares are highlighted in the magnified views. Scale bar = 5 μm. b Scheme showing the experimental protocols of 3 μM alpha -syn PFF exposure to oligodendroglial cells during two different phases (day 0–1, or day 3–4) of differentiation. c Cell viability analysis (WST assay) of day 8 OLGs, which were obtained through different protocols of alpha -syn PFF exposure during differentiation (no exposure, exposure on day 0–1, or exposure on days 3–4). N = 5, respectively, independent culture, Kruskal–Wallis, p* < 0.05. d Immunoblot analysis of day 8 OLGs obtained via different protocols of alpha -syn PFF exposure during differentiation (no exposure, exposure on day 0–1, or exposure on days 3–4), showing the protein expression levels of oligodendroglial cell markers. e, f Quantification of the relative protein expression levels of MBP (e) and BCAS1 (f) in day 8 OLGs obtained using the above-mentioned protocols. The differences between the no exposure group and day 0–1 group in (E) (p = 0.0636) and in (F) (p = 0.1980) were not statistically significant. N = 5, respectively, independent culture, Kruskal–Wallis, p* < 0.05, p** < 0.01. g Graphical representation of in vitro analysis showing two patterns of alpha -syn PFF-induced maturation inhibition. alpha -Syn PFF exposure to differentiating OLGs during the BCAS1(+) cell-dominant phase resulted in decreased cell viability (left), while exposure during the OPC-dominant phase resulted in abnormal protein expression levels of OLG markers (right) Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32727582), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse Olig2 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse Olig2 by Immunocytochemistry/Immunofluorescence Early onset of oligodendrocyte differentiation in Ptprz-deficient mice.A, Immunohistochemistry of cultured oligodendrocyte precursor cells (OPCs, NG2-postive cells, red) and oligodendrocytes (OLs, MBP-postive cells, green) from Ptprz-deficient mice and wild-type mice. Scale bars, 100 µm. The percentages of OPCs and OLs among total cells (DAPI-positive nuclei, blue) are shown at the right of each panel. Data are the mean ± SEM from five independent experiments. *p<0.05 and **p<0.01 (Student's t-test). B, Morphological assessment of cultured OLs at DIV6. The MBP-postive cells were classified into four categories. Representative images are shown in lower panels; Stage 1, three or less primary processes longer than a cell body with minimal development of secondary and tertiary processes; Stage 2, three or more primary processess with moderate secondary and tertiary processes; Stage 3, five or more primary processes with extensive secondry and teriary processes; Stage 4, extending myelin-like membrane structures and branched processes. Scale bars, 50 µm. Data are the mean ± SEM from three independent experiments. *p<0.05 (Mann-Whitney U-test). C, Ptprz expression in oligodendrocyte lineage cells. Cultured cells at DIV10 were triple stained with anti-RPTP beta (specific for Ptprz receptor isoforms, green), anti-Olig2 (red), and DAPI (blue). Scale bars, 50 µm. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0048797), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse Olig2 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse Olig2 by Immunocytochemistry/Immunofluorescence Pathological analysis of l2hgdh-/- mice.The figure compares the histological and ultrastructural appearance of the brain of l2hgdh+/+ (left panels: A, B, E, G, H, K, L) and l2hgdh-/- mice (right panels: C, D, F, I, J, M, N). Hematoxylin and eosin staining shows low-magnification of the lateral part of the brain (A, C) at the level of the lateral ventricle (LV), the caudate putamen (striatum; CPu) and the anterior commissure, anterior part (aca). Higher magnification of pencils of Wilson are shown in panels B and D. Notice the satellite oligodendrocyte at B (arrow). Luxol fast blue staining of myelin is shown in E and F, highlighting the predominant presence of vacuoles in the pencils of Wilson of the striatum of the l2hgdh-/- mouse. Panels G-J are microphotographs from the junction between cortex and white matter in the vicinity of corpus callosum. Immunostaining of NeuN (G and I) shows that most vacuoles in the l2hgdh-/- mice are at distance from the nucleus of neurons (notice the abundance of vacuoles in the lower part of panel I, devoid of neurons) although a few vacuoles indent the nucleus of some neurons (arrowheads). However, the nucleus of satellite oligodendrocytes is also present in close contact to the vacuole indenting the nucleus of some neurons (arrows), preventing to identify clearly which cell type actually contains the peri-neuronal vacuole. In contrast, immunostaining of Olig2 (H and J) clearly shows that most vacuoles are in close contact to the nucleus of oligodendrocytes in the l2hgdh-/- mouse brain. Notice the small size of the nucleus of oligodendrocytes compared to the nucleus of neurons. Panels K-N are Transmission Electron Microscopy photographs of striatum tissue. Ultrastructural analysis (K-N) shows many empty-looking cell processes (asterisks in panels M and N), containing dilated cytoplasmic organelles, in the glia of l2hgdh-/- mice. The myelin sheath of many axons appears focally altered or disrupted (arrows at M and N), sometimes at the vicinity of empty-looking spaces. C, capillary lumen. The length of the scale bar is indicated in each panel. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25763823), licensed under a CC-BY license. Not internally tested by R&D Systems.

In-situ Hybridization View Larger

Detection of Olig2 in Human Cortex. Formalin-fixed paraffin-embedded tissue sections of human cerebral cortex were probed for Olig2 mRNA (ACD RNAScope Probe, catalog #424198; Fast Red chromogen, ACD catalog # 322750). Adjacent tissue section was processed for immunohistochemistry using goat anti-human Olig2 polyclonal antibody (R&D Systems catalog # AF2418) at 3ug/mL with overnight incubation at 4 degrees Celsius followed by incubation with anti-goat IgG VisUCyte HRP Polymer Antibody (Catalog # VC004) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to glial cells.

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Preparation and Storage

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Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Olig2

Olig1 and Olig2 are basic-helix-loop-helix (bHLH) transcription factors expressed in the motor neuron progenitor (pMN) domain of the spinal cord that generates motor neurons and oligodendrocytes. Olig1 is involved in the development and maturation of oligodendrocytes. Olig2 is required for oligodendrocyte and motor neuron specification in the spinal cord.

Long Name
Oligodendrocyte Lineage Transcription Factor 2
Entrez Gene IDs
10215 (Human)
Alternate Names
BHLHB1; BHLHE19; Class B basic helix-loop-helix protein 1; Class E basic helix-loop-helix protein 19; human protein kinase C-binding protein RACK17; Olig2; OLIGO2; oligodendrocyte lineage transcription factor 2; oligodendrocyte transcription factor 2; oligodendrocyte-specific bHLH transcription factor 2; PRKCBP2; protein kinase C binding protein 2; Protein kinase C-binding protein 2; Protein kinase C-binding protein RACK17; RACK17; RACK17helix-loop-helix protein, class B, 1

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Citations for Human/Mouse/Rat Olig2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

190 Citations: Showing 1 - 10
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  1. G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD
    Authors: Coyne AN, Zaepfel BL, Hayes L et al.
    Neuron
  2. Oligodendroglia are particularly vulnerable to oxidative damage after neurotrauma in vivo
    Authors: MK Giacci, CA Bartlett, NM Smith, KS Iyer, LM Toomey, H Jiang, P Guagliardo, MR Kilburn, M Fitzgerald
    J. Neurosci., 2018-06-18;0(0):.
  3. Regulation of toll-like receptor 1 and -2 in neonatal mice brains after hypoxia-ischemia.
    Authors: Stridh L, Smith PL, Naylor AS et al.
    J Neuroinflammation.
  4. The Stem Cell Factor Sox2 Is a Positive Timer of Oligodendrocyte Development in the Postnatal Murine Spinal Cord.
    Authors: Zhang S, RaSai A, Wang Y et al.
    Mol. Neurobiol.
  5. Single cell transcriptomics reveals lineage trajectory of retinal ganglion cells in wild-type and Atoh7-null retinas
    Authors: Wu F, Bard JE, Kann J et al.
    Nature communications
  6. Hypoxia-induced release, nuclear translocation, and signaling activity of a DLK1 intracellular fragment in glioma
    Authors: ES Grassi, V Pantazopou, A Pietras
    Oncogene, 2020-03-24;0(0):.
  7. Arsenic Trioxide and (-)-Gossypol Synergistically Target Glioma Stem-Like Cells via Inhibition of Hedgehog and Notch Signaling
    Authors: Linder B, Wehle A, Hehlgans S et al.
    Cancers (Basel)
  8. Changes in arginase isoforms in a murine model of neonatal brain hypoxia-ischemia.
    Authors: Mike, J K, Pathipati, P Et al.
    Pediatr Res
  9. BRAF-V600E immunohistochemistry in a large series of glial and glial-neuronal tumors.
    Authors: Breton Q, Plouhinec H, Prunier-Mirebeau D et al.
    Brain Behav.
  10. Benchmark of cellular deconvolution methods using a multi-assay reference dataset from postmortem human prefrontal cortex
    Authors: Huuki-Myers, LA;Montgomery, KD;Kwon, SH;Cinquemani, S;Maden, SK;Eagles, NJ;Kleinman, JE;Hyde, TM;Hicks, SC;Maynard, KR;Collado-Torres, L;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  11. Stabilization of Pin1 by USP34 promotes Ubc9 isomerization and protein sumoylation in glioma stem cells
    Authors: Zhu, Q;Liang, P;Meng, H;Li, F;Miao, W;Chu, C;Wang, W;Li, D;Chen, C;Shi, Y;Yu, X;Ping, Y;Niu, C;Wu, HB;Zhang, A;Bian, XW;Zhou, W;
    Nature communications
    Species: Human, Xenograft
    Sample Types: Whole Tissue
    Applications: IHC
  12. Proteomic Analysis of Human iPSC-Derived Neural Stem Cells and Motor Neurons Identifies Proteasome Structural Alterations
    Authors: Álvarez, I;Tirado-Herranz, A;Alvarez-Palomo, B;Osete, JR;Edel, MJ;
    Cells
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  13. Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia
    Authors: Garza, R;Sharma, Y;Atacho, DAM;Thiruvalluvan, A;Abu Hamdeh, S;Jönsson, ME;Horvath, V;Adami, A;Ingelsson, M;Jern, P;Hammell, MG;Englund, E;Kirkeby, A;Jakobsson, J;Marklund, N;
    Cell reports
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  14. Truncated radial glia as a common precursor in the late corticogenesis of gyrencephalic mammals
    Authors: Bilgic, M;Wu, Q;Suetsugu, T;Shitamukai, A;Tsunekawa, Y;Shimogori, T;Kadota, M;Nishimura, O;Kuraku, S;Kiyonari, H;Matsuzaki, F;
    eLife
    Species: Ferret
    Sample Types: Whole Tissue
    Applications: IHC
  15. Erythropoietin regulates developmental myelination in the brain stimulating postnatal oligodendrocyte maturation
    Authors: Muttathukunnel, P;Wälti, M;Aboouf, MA;Köster-Hegmann, C;Haenggi, T;Gassmann, M;Pannzanelli, P;Fritschy, JM;Schneider Gasser, EM;
    Scientific reports
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  16. HMGB1 induces hepcidin upregulation in astrocytes and causes an acute iron surge and subsequent ferroptosis in the postischemic brain
    Authors: Davaanyam, D;Lee, H;Seol, SI;Oh, SA;Kim, SW;Lee, JK;
    Experimental & molecular medicine
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  17. Effects of Gestational and Lactational Lead Exposure and High Fat Diet Feeding on Cerebellar Development of Postnatal Rat Offspring
    Authors: Seo, JS;Lee, SH;Won, HS;Yang, M;Nahm, SS;Nam, SM;
    Nutrients
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  18. hGFAP-mediated GLI2 overexpression leads to early death and severe cerebellar malformations with rare tumor formation
    Authors: Judith Niesen, Irm Hermans-Borgmeyer, Christina Krüger, Melanie Schoof, Franziska Modemann, Ulrich Schüller
    iScience
  19. Targeted mechanical stimulation via magnetic nanoparticles guides in vitro tissue development
    Authors: Abdel Fattah, AR;Kolaitis, N;Van Daele, K;Daza, B;Rustandi, AG;Ranga, A;
    Nature communications
    Species: Mouse
    Sample Types: Organoids
    Applications: IHC
  20. The Single-Dose Application of Interleukin-4 Ameliorates Secondary Brain Damage in the Early Phase after Moderate Experimental Traumatic Brain Injury in Mice
    Authors: Walter, J;Mende, J;Hutagalung, S;Alhalabi, OT;Grutza, M;Zheng, G;Skutella, T;Unterberg, A;Zweckberger, K;Younsi, A;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  21. Deciphering the Action of Neuraminidase in Glioblastoma Models
    Authors: Baeza-Kallee, N;Bergès, R;Hein, V;Cabaret, S;Garcia, J;Gros, A;Tabouret, E;Tchoghandjian, A;Colin, C;Figarella-Branger, D;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  22. Progranulin deficiency results in sex-dependent alterations in microglia in response to demyelination
    Authors: Zhang T, Feng T, Wu K et al.
    Acta Neuropathologica
  23. Two different isoforms of osteopontin modulate myelination and axonal integrity
    Authors: Nilsson G, Mottahedin A, Zelco A et al.
    FASEB BioAdvances
  24. Age-appropriate potassium clearance from perinatal cerebrospinal fluid depends on choroid plexus NKCC1
    Authors: Ryann M. Fame, Huixin Xu, Aja Pragana, Maria Lehtinen
    Fluids and Barriers of the CNS
  25. Cell Type Specific CAG Repeat Expansions and Toxicity of Mutant Huntingtin in Human Striatum and Cerebellum
    Authors: Mätlik, K;Baffuto, M;Kus, L;Deshmukh, AL;Davis, DA;Paul, MR;Carroll, TS;Caron, MC;Masson, JY;Pearson, CE;Heintz, N;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Nuclei, Tissue Homogenates
    Applications: Flow Cytometry, Western Blot
  26. Brain matters: unveiling the distinct contributions of region, age, and sex to glia diversity and�CNS function
    Authors: Seeker, LA;Bestard-Cuche, N;J�kel, S;Kazakou, NL;B�strand, SMK;Wagstaff, LJ;Cholewa-Waclaw, J;Kilpatrick, AM;Van Bruggen, D;Kabbe, M;Baldivia Pohl, F;Moslehi, Z;Henderson, NC;Vallejos, CA;La Manno, G;Castelo-Branco, G;Williams, A;
    Acta neuropathologica communications
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  27. Free fatty acids support oligodendrocyte survival in a mouse model of amyotrophic lateral sclerosis
    Authors: Maruyama, T;Tanabe, S;Uyeda, A;Suzuki, T;Muramatsu, R;
    Frontiers in cellular neuroscience
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  28. Expression patterns of NKCC1 in neurons and non-neuronal cells during cortico-hippocampal development
    Authors: Samu N Kurki, Pavel Uvarov, Alexey S Pospelov, Kalevi Trontti, Antje K Hübner, Rakenduvadhana Srinivasan et al.
    Cerebral Cortex
  29. TMEM106B regulates microglial proliferation and survival in response to demyelination
    Authors: Zhang, T;Pang, W;Feng, T;Guo, J;Wu, K;Nunez Santos, M;Arthanarisami, A;Nana, AL;Nguyen, Q;Kim, PJ;Jankowsky, JL;Seeley, WW;Hu, F;
    Science advances
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  30. Layer 5a Corticostriatal Projection Neurons are Selectively Vulnerable in Huntington's Disease
    Authors: Pressl, C;M�tlik, K;Kus, L;Darnell, P;Luo, JD;Weiss, AR;Liguore, W;Carroll, TS;Davis, DA;McBride, J;Heintz, N;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Nuclei
    Applications: ICC
  31. Regulatory T cells alleviate myelin loss and cognitive dysfunction by regulating neuroinflammation and microglial pyroptosis via TLR4/MyD88/NF-kappaB pathway in LPC-induced demyelination
    Authors: Y Wang, D Sadike, B Huang, P Li, Q Wu, N Jiang, Y Fang, G Song, L Xu, W Wang, M Xie
    Journal of Neuroinflammation, 2023-02-18;20(1):41.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  32. IFN-?-STAT1-mediated CD8+ T-cell-neural stem cell cross talk controls astrogliogenesis after spinal cord injury
    Authors: Wang J, Xu L, Peng D et al.
    Inflammation and regeneration
  33. Single-cell RNA-sequencing identifies disease-associated oligodendrocytes in male APP NL-G-F and 5XFAD mice
    Authors: H Park, B Cho, H Kim, T Saito, TC Saido, KJ Won, J Kim
    Nature Communications, 2023-02-13;14(1):802.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  34. Technique of flat-mount immunostaining for mapping the olfactory epithelium and counting the olfactory sensory neurons
    Authors: Marie Gavid, Louise Coulomb, Justin Thomas, Inès Aouimeur, Paul Verhoeven, Marielle Mentek et al.
    PLOS ONE
  35. Early Permissiveness of Central Nervous System Cells to Measles Virus Infection Is Determined by Hyperfusogenicity and Interferon Pressure
    Authors: M Ferren, A Lalande, M Iampietro, L Canus, D Decimo, D Gerlier, M Porotto, C Mathieu
    Viruses, 2023-01-13;15(1):.
    Species: Hamster - Mesocricetus auratus (Golden Hamster)
    Sample Types: Whole Tissue
    Applications: Bioassay
  36. Astrocyte heterogeneity within white matter tracts and a unique subpopulation of optic nerve head astrocytes
    Authors: Arpan G. Mazumder, Amélie M. Julé, Paul F. Cullen, Daniel Sun
    iScience
  37. Neurogenesis potential of oligodendrocyte precursor cells from oligospheres and injured spinal cord
    Authors: Qing Zhao, Yanjing Zhu, Yilong Ren, Shuai Yin, Liqun Yu, Ruiqi Huang et al.
    Frontiers in Cellular Neuroscience
  38. Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer's disease
    Authors: S Chen, Y Chang, L Li, D Acosta, Y Li, Q Guo, C Wang, E Turkes, C Morrison, D Julian, ME Hester, DW Scharre, C Santiskulv, SX Song, JT Plummer, GE Serrano, TG Beach, KE Duff, Q Ma, H Fu
    Acta neuropathologica communications, 2022-12-21;10(1):188.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  39. An atlas of late prenatal human neurodevelopment resolved by single-nucleus transcriptomics
    Authors: SI Ramos, ZM Mussa, EN Falk, B Pai, B Giotti, K Allette, P Cai, F Dekio, R Sebra, KG Beaumont, AM Tsankov, NM Tsankova
    Nature Communications, 2022-12-12;13(1):7671.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC/IF
  40. CHRDL1 Regulates Stemness in Glioma Stem-like Cells
    Authors: I Berglar, S Hehlgans, A Wehle, C Roth, C Herold-Men, F Rödel, D Kögel, B Linder
    Cells, 2022-12-03;11(23):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  41. Oligodendrocyte lineage is severely affected in human alcohol-exposed foetuses
    Authors: Florent Marguet, Mélanie Brosolo, Gaëlle Friocourt, Fanny Sauvestre, Pascale Marcorelles, Céline Lesueur et al.
    Acta Neuropathologica Communications
  42. Phloretin enhances remyelination by stimulating oligodendrocyte precursor cell differentiation
    Authors: T Dierckx, S Vanherle, M Haidar, E Grajchen, F Mingneau, P Gervois, E Wolfs, D Bylemans, A Voet, T Nguyen, I Hamad, M Kleinewiet, JFJ Bogie, JJA Hendriks
    Proceedings of the National Academy of Sciences of the United States of America, 2022-11-07;119(46):e2120393119.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  43. A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan
    Authors: Y Su, Y Zhou, ML Bennett, S Li, M Carceles-C, L Lu, S Huh, D Jimenez-Cy, BC Kennedy, SK Kessler, AN Viaene, I Helbig, X Gu, JE Kleinman, TM Hyde, DR Weinberger, DW Nauen, H Song, GL Ming
    Cell Stem Cell, 2022-11-03;29(11):1594-1610.e8.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  44. Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice
    Authors: T Zhou, Y Li, X Li, F Zeng, Y Rao, Y He, Y Wang, M Liu, D Li, Z Xu, X Zhou, S Du, F Niu, J Peng, X Mei, SJ Ji, Y Shu, W Lu, F Guo, T Wu, TF Yuan, Y Mao, B Peng
    Nature Communications, 2022-10-24;13(1):6233.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  45. High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy
    Authors: B Pai, J Tome-Garci, WS Cheng, G Nudelman, KG Beaumont, S Ghatan, F Panov, E Caballero, K Sarpong, L Marcuse, J Yoo, Y Jiang, A Schaefer, S Akbarian, R Sebra, D Pinto, E Zaslavsky, NM Tsankova
    Acta neuropathologica communications, 2022-10-23;10(1):149.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  46. Guidance landscapes unveiled by quantitative proteomics to control reinnervation in adult visual system
    Authors: N Vilallongu, J Schaeffer, AM Hesse, C Delpech, B Blot, A Paccard, E Plissonnie, B Excoffier, Y Couté, S Belin, H Nawabi
    Nature Communications, 2022-10-13;13(1):6040.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  47. Single-cell transcriptomics reveals functionally specialized vascular endothelium in brain
    Authors: Hyun-Woo Jeong, Rodrigo Diéguez-Hurtado, Hendrik Arf, Jian Song, Hongryeol Park, Kai Kruse et al.
    eLife
  48. The alarmin interleukin-1? triggers secondary degeneration through reactive astrocytes and endothelium after spinal cord injury
    Authors: Bretheau F, Castellanos-Molina A, B�langer D et al.
    Nature Communications
  49. A TCF7L2-responsive suppression of both homeostatic and compensatory remyelination in Huntington disease mice
    Authors: A Benraiss, JN Mariani, A Tate, PM Madsen, KM Clark, KA Welle, R Solly, L Capellano, K Bentley, D Chandler-M, SA Goldman
    Cell Reports, 2022-08-30;40(9):111291.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  50. DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential
    Authors: Bruno Frederico, Isaura Martins, Diana Chapela, Francesca Gasparrini, Probir Chakravarty, Tobias Ackels et al.
    Developmental Cell
  51. Expression of antioxidant enzymes in lesions of multiple sclerosis and its models
    Authors: D Moezzi, Y Dong, RW Jain, BM Lozinski, S Ghorbani, C D'Mello, V Wee Yong
    Scientific Reports, 2022-07-26;12(1):12761.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  52. Molecular landscapes of human hippocampal immature neurons across lifespan
    Authors: Y Zhou, Y Su, S Li, BC Kennedy, DY Zhang, AM Bond, Y Sun, F Jacob, L Lu, P Hu, AN Viaene, I Helbig, SK Kessler, T Lucas, RD Salinas, X Gu, HI Chen, H Wu, JE Kleinman, TM Hyde, DW Nauen, DR Weinberger, GL Ming, H Song
    Nature, 2022-07-06;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  53. Apelin alleviated neuroinflammation and promoted endogenous neural stem cell proliferation and differentiation after spinal cord injury in rats
    Authors: Q Liu, S Zhou, X Wang, C Gu, Q Guo, X Li, C Zhang, N Zhang, L Zhang, F Huang
    Journal of Neuroinflammation, 2022-06-20;19(1):160.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  54. Telomere Attrition in Induced Pluripotent Stem Cell-Derived Neurons From ALS/FTD-Related C9ORF72 Repeat Expansion Carriers
    Authors: Hayley Robinson, Sk Imran Ali, Martha Elena Diaz-Hernandez, Rodrigo Lopez-Gonzalez
    Frontiers in Cell and Developmental Biology
  55. A timeline of oligodendrocyte death and proliferation following experimental subarachnoid hemorrhage
    Authors: Kang Peng, Sravanthi Koduri, Fenghui Ye, Jinting Yang, Richard F. Keep, Guohua Xi et al.
    CNS Neuroscience & Therapeutics
  56. Cerebrospinal fluid of progressive multiple sclerosis patients reduces differentiation and immune functions of oligodendrocyte progenitor cells
    Authors: Omri Zveik, Nina Fainstein, Ariel Rechtman, Nitzan Haham, Tal Ganz, Iris Lavon et al.
    Glia
  57. Defining Longer-Term Outcomes in an Ovine Model of Moderate Perinatal Hypoxia-Ischemia
    Authors: Mike JK, Wu KY, White Y et al.
    Developmental Neuroscience
  58. Developmental window of vulnerability to white matter injury driven by sublethal intermittent hypoxemia
    Authors: Sergey A. Sosunov, Zoya V. Niatsetskaya, Anna A. Stepanova, Alexander S. Galkin, Courtney E. Juliano, Veniamin I. Ratner et al.
    Pediatric Research
  59. High-Throughput Analysis of Astrocyte Cultures Shows Prevention of Reactive Astrogliosis by the Multi-Nutrient Combination Fortasyn Connect
    Authors: A Badia-Sote, J de Vries, W Dykstra, LM Broersen, JM Verkuyl, AB Smit, MHG Verheijen
    Cells, 2022-04-22;11(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  60. Bu Shen Yi Sui Capsules Promote Remyelination by Regulating MicroRNA-219 and MicroRNA-338 in Exosomes to Promote Oligodendrocyte Precursor Cell Differentiation
    Authors: Jing Ji, Ya-Qin Sun, Zheng Zha, Bing Xue, Jun-Ling Li, Liang-Yun Jin et al.
    Evidence-Based Complementary and Alternative Medicine
  61. Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties
    Authors: C Azevedo, G Teku, Y Pomeshchik, JF Reyes, M Chumarina, K Russ, E Savchenko, A Hammarberg, NJ Lamas, A Collin, GK Gouras, O Klementiev, M Hallbeck, R Taipa, M Vihinen, L Roybon
    Proceedings of the National Academy of Sciences of the United States of America, 2022-03-16;119(12):e2111405119.
    Species: Human
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  62. TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss
    Authors: T Feng, L Luan, II Katz, M Ullah, VM Van Deerli, JQ Trojanowsk, EB Lee, F Hu
    Acta neuropathologica communications, 2022-03-14;10(1):33.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  63. The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development
    Authors: W Wang, H Cho, JW Lee, SK Lee
    Nature Communications, 2022-02-17;13(1):958.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  64. Multiple therapeutic effects of human neural stem cells derived from induced pluripotent stem cells in a rat model of post-traumatic syringomyelia
    Authors: T Xu, X Li, Y Guo, E Uhlin, L Holmberg, S Mitra, D Winn, A Falk, E Sundström
    EBioMedicine, 2022-02-16;77(0):103882.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  65. BMP10 expression in the adult rat central nervous system
    Authors: C Ogawa, S Mikawa, S Li, Y Hayashi, K Masumoto, K Sato
    Journal of chemical neuroanatomy, 2022-02-16;121(0):102084.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  66. A gut-derived metabolite alters brain activity and anxiety behaviour in mice
    Authors: BD Needham, M Funabashi, MD Adame, Z Wang, JC Boktor, J Haney, WL Wu, C Rabut, MS Ladinsky, SJ Hwang, Y Guo, Q Zhu, JA Griffiths, R Knight, PJ Bjorkman, MG Shapiro, DH Geschwind, DP Holschneid, MA Fischbach, SK Mazmanian
    Nature, 2022-02-14;602(7898):647-653.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  67. Ponesimod inhibits astrocyte‐mediated neuroinflammation and protects against cingulum demyelination via S1P 1 ‐selective modulation
    Authors: Yasuyuki Kihara, Deepa Jonnalagadda, Yunjiao Zhu, Manisha Ray, Tony Ngo, Carter Palmer et al.
    The FASEB Journal
  68. Selective translation of epigenetic modifiers affects the temporal pattern and differentiation of neural stem cells
    Authors: Q Wu, Y Shichino, T Abe, T Suetsugu, A Omori, H Kiyonari, S Iwasaki, F Matsuzaki
    Nature Communications, 2022-01-25;13(1):470.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  69. Extracellular Vesicles Derived from Young Neural Cultures Attenuate Astrocytic Reactivity In Vitro
    Authors: D Almansa, H Peinado, R García-Rod, Á Casadomé-P, CG Dotti, FX Guix
    International Journal of Molecular Sciences, 2022-01-25;23(3):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  70. Profiling Glioblastoma Cases with an Expression of DCX, OLIG2 and NES
    Authors: Adrian Odrzywolski, Bożena Jarosz, Michał Kiełbus, Ilona Telejko, Dominik Ziemianek, Sebastian Knaga et al.
    International Journal of Molecular Sciences
  71. A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation
    Authors: Jiayang Chen, Mary E. Lambo, Xia Ge, Joshua T. Dearborn, Yating Liu, Katherine B. McCullough et al.
    Neuron
  72. Evidence for glutamine synthetase function in mouse spinal cord oligodendrocytes
    Authors: Lucile Ben Ben Haim, Lucas Schirmer, Amel Zulji, Khalida Sabeur, Brice Tiret, Matthieu Ribon et al.
    Glia
  73. A Novel Vitronectin Peptide Facilitates Differentiation of Oligodendrocytes from Human Pluripotent Stem Cells (Synthetic ECM for Oligodendrocyte Differentiation)
    Authors: WU Park, GB Yeon, MS Yu, HG Goo, SH Hwang, D Na, DS Kim
    Biology, 2021-12-01;10(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  74. Studying the microglia response to oxidized phosphatidylcholine in primary mouse neuron culture and mouse spinal cord
    Authors: Yifei Dong, Brian M. Lozinski, Claudia Silva, V. Wee Yong
    STAR Protocols
  75. Cuprizone feed formulation influences the extent of demyelinating disease pathology
    Authors: LM Toomey, M Papini, B Lins, AJ Wright, A Warnock, T McGonigle, SC Hellewell, CA Bartlett, C Anyaegbu, M Fitzgerald
    Scientific Reports, 2021-11-19;11(1):22594.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  76. IL-33 induces orofacial neuropathic pain through Fyn-dependent phosphorylation of GluN2B in the trigeminal spinal nucleus caudalis
    Authors: Y Kimura, Y Hayashi, S Hitomi, D Ikutame, K Urata, I Shibuta, A Sakai, J Ni, K Iwata, M Tonogi, M Shinoda
    Brain, Behavior, and Immunity, 2021-10-26;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  77. Highly efficient manipulation of nervous system gene expression with NEPTUNE
    Authors: Katrin Mangold, Jan Mašek, Jingyan He, Urban Lendahl, Elaine Fuchs, Emma R. Andersson
    Cell Reports Methods
  78. Plasticity-Enhancing Effects of Levodopa Treatment after Stroke
    Authors: Daniela Talhada, Niklas Marklund, Tadeusz Wieloch, Enida Kuric, Karsten Ruscher
    International Journal of Molecular Sciences
  79. Microglial ASD-related genes are involved in oligodendrocyte differentiation
    Authors: Y Takanezawa, S Tanabe, D Kato, R Ozeki, M Komoda, T Suzuki, H Baba, R Muramatsu
    Scientific Reports, 2021-09-08;11(1):17825.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  80. Transplantable human motor networks as a neuron-directed strategy for spinal cord injury
    Authors: Zachary T. Olmsted, Cinzia Stigliano, Annalisa Scimemi, Tatiana Wolfe, Jose Cibelli, Philip J. Horner et al.
    iScience
  81. Maternal high-fat diet modifies myelin organization, microglial interactions, and results in social memory and sensorimotor gating deficits in adolescent mouse offspring
    Authors: Maude Bordeleau, Lourdes Fernández de Cossío, Chloé Lacabanne, Julie C. Savage, Nathalie Vernoux, Mallar Chakravarty et al.
    Brain, Behavior, & Immunity - Health
  82. Single-cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human-specific features
    Authors: Teresa Rayon, Rory J. Maizels, Christopher Barrington, James Briscoe
    Development
  83. A Novel Mutation in Cse1l Disrupts Brain and Eye Development with Specific Effects on Pax6 Expression
    Authors: LE Blizzard, C Menke, SD Patel, RR Waclaw, SA Lachke, RW Stottmann
    Journal of developmental biology, 2021-07-07;9(3):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  84. Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus
    Authors: Betsaida Ojeda-Pérez, José A. Campos-Sandoval, María García-Bonilla, Casimiro Cárdenas-García, Patricia Páez-González, Antonio J. Jiménez
    Fluids and Barriers of the CNS
  85. Nanoparticulate matter exposure results in white matter damage and an inflammatory microglial response in an experimental murine model
    Authors: M Connor, K Lamorie-Fo, Q Liu, K Shkirkova, H Baertsch, C Sioutas, TE Morgan, CE Finch, WJ Mack
    PLoS ONE, 2021-07-02;16(7):e0253766.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  86. Generation of excitatory and inhibitory neurons from common progenitors via Notch signaling in the cerebellum
    Authors: T Zhang, T Liu, N Mora, J Guegan, M Bertrand, X Contreras, AH Hansen, C Streicher, M Anderle, N Danda, L Tiberi, S Hippenmeye, BA Hassan
    Cell Reports, 2021-06-08;35(10):109208.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  87. CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity
    Authors: P Filppu, JT Ramanathan, KJ Granberg, E Gucciardo, H Haapasalo, K Lehti, M Nykter, V Le Joncour, P Laakkonen
    JCI Insight, 2021-05-10;6(9):.
    Species: Human
    Sample Types: Cell Lysates, Whole Tissue
    Applications: Co-Immunoprecipitation, IHC, Western Blot
  88. Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice
    Authors: W Mu, S Li, J Xu, X Guo, H Wu, Z Chen, L Qiao, G Helfer, F Lu, C Liu, QF Wu
    Nature Communications, 2021-04-16;12(1):2288.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  89. Olig2 regulates p53-mediated apoptosis, migration and invasion of melanoma cells
    Authors: JE Lee, S Ahn, H Jeong, S An, CH Myung, JA Lee, SC Hong, YJ Kim, JY Kim, JH Ryu, M Noh, KT Nam, JS Hwang
    Scientific Reports, 2021-04-08;11(1):7778.
    Species: Human
    Sample Types: Cell Lysates, Whole Tissue
    Applications: IHC, Western Blot
  90. Bu Shen Yi Sui Capsule Alleviates Neuroinflammation and Demyelination by Promoting Microglia toward M2 Polarization, Which Correlates with Changes in miR-124 and miR-155 in Experimental Autoimmune Encephalomyelitis
    Authors: Zheng Zha, Yan-Fang Gao, Jing Ji, Ya-Qin Sun, Jun-Ling Li, Fang Qi et al.
    Oxidative Medicine and Cellular Longevity
  91. Liproxstatin-1 is an effective inhibitor of oligodendrocyte ferroptosis induced by inhibition of glutathione peroxidase 4
    Authors: BY Fan, YL Pang, WX Li, CX Zhao, Y Zhang, X Wang, GZ Ning, XH Kong, C Liu, X Yao, SQ Feng
    Neural regeneration research, 2021-03-01;16(3):561-566.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  92. Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia
    Authors: Y Dong, C D'Mello, W Pinsky, BM Lozinski, DK Kaushik, S Ghorbani, D Moezzi, D Brown, FC Melo, S Zandee, T Vo, A Prat, SN Whitehead, VW Yong
    Nature Neuroscience, 2021-02-18;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  93. Precision of tissue patterning is controlled by dynamical properties of gene regulatory networks
    Authors: Katherine Exelby, Edgar Herrera-Delgado, Lorena Garcia Perez, Ruben Perez-Carrasco, Andreas Sagner, Vicki Metzis et al.
    Development
  94. BMP9 expression in the adult rat brain
    Authors: C Ogawa, S Mikawa, Y Hayashi, K Masumoto, F Katou, K Sato
    Journal of chemical neuroanatomy, 2021-02-11;113(0):101933.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  95. AIM2 inflammasome mediates hallmark neuropathological alterations and cognitive impairment in a mouse model of vascular dementia
    Authors: L Poh, DY Fann, P Wong, HM Lim, SL Foo, SW Kang, V Rajeev, S Selvaraji, VR Iyer, N Parathy, MB Khan, DC Hess, DG Jo, GR Drummond, CG Sobey, MKP Lai, CL Chen, LHK Lim, TV Arumugam
    Molecular Psychiatry, 2020-12-09;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  96. Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury
    Authors: Manideep Chavali, Maria José Ulloa-Navas, Pedro Pérez-Borredá, Jose Manuel Garcia-Verdugo, Patrick S. McQuillen, Eric J. Huang et al.
    Neuron
  97. Multimodal single-cell analysis reveals distinct radioresistant stem-like and progenitor cell populations in murine glioma
    Authors: Jes Alexander, Quincey C. LaPlant, Siobhan S. Pattwell, Frank Szulzewsky, Patrick J. Cimino, Francesca P. Caruso et al.
    Glia
  98. SATB2 drives glioblastoma growth by recruiting CBP to promote FOXM1 expression in glioma stem cells
    Authors: W Tao, A Zhang, K Zhai, Z Huang, H Huang, W Zhou, Q Huang, X Fang, BC Prager, X Wang, Q Wu, AE Sloan, MS Ahluwalia, JD Lathia, JS Yu, JN Rich, S Bao
    EMBO Mol Med, 2020-10-30;0(0):e12291.
    Species: Human, Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  99. Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts
    Authors: AL Koessinger, D Koessinger, K Stevenson, C Cloix, L Mitchell, C Nixon, N Gomez-Roma, AJ Chalmers, JC Norman, SWG Tait
    Scientific Reports, 2020-09-21;10(1):15361.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  100. PRC2 Acts as a Critical Timer That Drives Oligodendrocyte Fate over Astrocyte Identity by Repressing the Notch Pathway
    Authors: W Wang, H Cho, D Kim, Y Park, JH Moon, SJ Lim, SM Yoon, M McCane, SA Aicher, S Kim, B Emery, JW Lee, S Lee, Y Park, SK Lee
    Cell Rep, 2020-09-15;32(11):108147.
    Species: Chicken, Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  101. Cyclophilin D–dependent oligodendrocyte mitochondrial ion leak contributes to neonatal white matter injury
    Authors: Zoya Niatsetskaya, Sergey Sosunov, Anna Stepanova, James Goldman, Alexander Galkin, Maria Neginskaya et al.
    Journal of Clinical Investigation
  102. Single-Cell Profiling Shows Murine Forebrain Neural Stem Cells Reacquire a Developmental State when Activated for Adult Neurogenesis
    Authors: MJ Borrett, BT Innes, D Jeong, N Tahmasian, MA Storer, GD Bader, DR Kaplan, FD Miller
    Cell Rep, 2020-08-11;32(6):108022.
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: FISH, IHC
  103. Origins and Proliferative States of Human Oligodendrocyte Precursor Cells
    Authors: Wei Huang, Aparna Bhaduri, Dmitry Velmeshev, Shaohui Wang, Li Wang, Catherine A. Rottkamp et al.
    Cell
  104. BCAS1-positive immature oligodendrocytes are affected by the &alpha-synuclein-induced pathology of multiple system atrophy
    Authors: S Kaji, T Maki, J Ueda, T Ishimoto, Y Inoue, K Yasuda, M Sawamura, R Hikawa, T Ayaki, H Yamakado, R Takahashi
    Acta Neuropathol Commun, 2020-07-29;8(1):120.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  105. EEF1A1 deacetylation enables transcriptional activation of remyelination
    Authors: M Duman, A Vaquié, G Nocera, M Heller, M Stumpe, D Siva Sanka, J Dengjel, D Meijer, T Yamaguchi, P Matthias, T Zeis, N Schaeren-W, A Hayoz, S Ruff, C Jacob
    Nat Commun, 2020-07-09;11(1):3420.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  106. Spontaneous Local Calcium Transients Regulate Oligodendrocyte Development in Culture through Store-Operated Ca2+ Entry and Release
    Authors: Yanfang Rui, Stephanie L. Pollitt, Kenneth R. Myers, Yue Feng, James Q. Zheng
    eNeuro
  107. Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex–mediated STAT1 downregulation
    Authors: Xiaoyan Zhan, Saisai Guo, Yuanyuan Li, Haowen Ran, Haohao Huang, Lanjuan Mi et al.
    Journal of Experimental Medicine
  108. Ginseng gintonin alleviates neurological symptoms in the G93A-SOD1 transgenic mouse model of amyotrophic lateral sclerosis through lysophosphatidic acid 1 receptor
    Authors: SM Nam, JH Choi, SH Choi, HJ Cho, YJ Cho, H Rhim, HC Kim, IH Cho, DG Kim, SY Nah
    Journal of Ginseng Research, 2020-05-01;45(3):390-400.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  109. A Matter of Choice: Inhibition of c-Rel Shifts Neuronal to Oligodendroglial Fate in Human Stem Cells
    Authors: LM Ruiz-Perer, JFW Greiner, C Kaltschmid, B Kaltschmid
    Cells, 2020-04-22;9(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  110. An ocular glymphatic clearance system removes beta -amyloid from the rodent eye
    Authors: Xiaowei Wang, Nanhong Lou, Allison Eberhardt, Yujia Yang, Peter Kusk, Qiwu Xu et al.
    Science Translational Medicine
  111. Spatiotemporal Decline of BMP Signaling Activity in Neural Progenitors Mediates Fate Transition and Safeguards Neurogenesis
    Authors: TC Ma, KI Vong, KM Kwan
    Cell Rep, 2020-03-17;30(11):3616-3624.e4.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  112. Pathological modeling of TBEV infection reveals differential innate immune responses in human neurons and astrocytes that correlate with their susceptibility to infection
    Authors: M Fares, M Cochet-Ber, G Gonzalez, CN Montero-Me, O Blanchet, A Benchoua, C Boissart, S Lecollinet, J Richardson, N Haddad, M Coulpier
    J Neuroinflammation, 2020-03-03;17(1):76.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  113. Ginseng Gintonin Attenuates Lead-Induced Rat Cerebellar Impairments during Gestation and Lactation
    Authors: SM Nam, SH Choi, HJ Cho, JS Seo, M Choi, SS Nahm, BJ Chang, SY Nah
    Biomolecules, 2020-03-02;10(3):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  114. Pericyte-Mediated Tissue Repair through PDGFR beta Promotes Peri-Infarct Astrogliosis, Oligodendrogenesis, and Functional Recovery after Acute Ischemic Stroke
    Authors: Tomoya Shibahara, Tetsuro Ago, Kuniyuki Nakamura, Masaki Tachibana, Yoji Yoshikawa, Motohiro Komori et al.
    eNeuro
  115. Follistatin expression in the central nervous system of the adult rat
    Authors: C Ogawa, S Mikawa, K Yamashita, Y Hayashi, K Masumoto, F Katou, K Sato
    J. Chem. Neuroanat., 2020-01-31;105(0):101753.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  116. Motor function deficits in the estrogen receptor beta knockout mouse: Role on excitatory neurotransmission and myelination in the motor cortex.
    Authors: Mukesh V, Nancy Y, Shintaro K et al.
    Neuroendocrinology.
  117. Protein corona formation moderates the release kinetics of ion channel antagonists from transferrin-functionalized polymeric nanoparticles†
    Authors: Priya S. R. Naidu, Eleanor Denham, Carole A. Bartlett, Terry McGonigle, Nicolas L. Taylor, Marck Norret et al.
    RSC Advances
  118. Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease
    Authors: Y Zhou, WM Song, PS Andhey, A Swain, T Levy, KR Miller, PL Poliani, M Cominelli, S Grover, S Gilfillan, M Cella, TK Ulland, K Zaitsev, A Miyashita, T Ikeuchi, M Sainouchi, A Kakita, DA Bennett, JA Schneider, MR Nichols, SA Beausoleil, JD Ulrich, DM Holtzman, MN Artyomov, M Colonna
    Nat. Med., 2020-01-13;26(1):131-142.
    Species: Mouse
    Sample Types: Tissue
    Applications: IHC
  119. Chromosome Translocation t(14;21)(q11;q22) Activates Both OLIG1 and OLIG2 in Pediatric T-cell Lymphoblastic Malignancies and May Signify Adverse Prognosis
    Authors: IOANNIS PANAGOPOULOS, LUDMILA GORUNOVA, INGA MARIA RINVOLL JOHANNSDOTTIR, KRISTIN ANDERSEN, ARILD HOLTH, KLAUS BEISKE et al.
    Cancer Genomics - Proteomics
  120. Cortical astrocytes develop in a plastic manner at both clonal and cellular levels
    Authors: S Clavreul, L Abdeladim, E Hernández-, D Niculescu, J Durand, SH Ieng, R Barry, G Bonvento, E Beaurepair, J Livet, K Loulier
    Nat Commun, 2019-10-25;10(1):4884.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  121. Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection
    Authors: LM Toomey, CA Bartlett, N Gavriel, T McGonigle, M Majimbi, G Gopalasing, J Rodger, M Fitzgerald
    Sci Rep, 2019-10-25;9(1):15297.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  122. Precocious myelination in a mouse model of autism
    Authors: Maryam Khanbabaei, Elizabeth Hughes, Jacob Ellegood, Lily R. Qiu, Raven Yip, Jenna Dobry et al.
    Translational Psychiatry
  123. Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements
    Authors: Gi Bum Kim, David Rincon Fernandez Rincon Fernandez Pacheco, David Saxon, Amy Yang, Sara Sabet, Marina Dutra-Clarke et al.
    Cell
  124. Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells
    Authors: Zachary J. Reitman, Brenton R. Paolella, Guillaume Bergthold, Kristine Pelton, Sarah Becker, Robert Jones et al.
    Nature Communications
  125. Chronic disturbance in the thalamus following cranial irradiation to the developing mouse brain
    Authors: M Boström, Y Eriksson, J Danial, T Björk-Erik, M Kalm
    Sci Rep, 2019-07-03;9(1):9588.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  126. Transforming growth factor‐beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitors
    Authors: Roey Baror, Björn Neumann, Michael Segel, Kevin J. Chalut, Stephen P. J. Fancy, Dorothy P. Schafer et al.
    Glia
  127. The effects of a combination of ion channel inhibitors on pathology in a model of demyelinating disease
    Authors: G Gopalasing, CA Bartlett, T McGonigle, M Majimbi, A Warnock, A Ford, A Gough, LM Toomey, M Fitzgerald
    Mult Scler Relat Disord, 2019-06-08;34(0):1-8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  128. Circulating transforming growth factor-beta 1 facilitates remyelination in the adult central nervous system
    Authors: Machika Hamaguchi, Rieko Muramatsu, Harutoshi Fujimura, Hideki Mochizuki, Hirotoshi Kataoka, Toshihide Yamashita
    eLife
  129. CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes
    Authors: Penelope Dimas, Laura Montani, Jorge A Pereira, Daniel Moreno, Martin Trötzmüller, Joanne Gerber et al.
    eLife
  130. BMP6 expression in the adult rat central nervous system
    Authors: Y Hayashi, S Mikawa, C Ogawa, K Masumoto, F Katou, K Sato
    J. Chem. Neuroanat., 2019-03-27;0(0):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  131. Altered human oligodendrocyte heterogeneity in multiple sclerosis
    Authors: Sarah Jäkel, Eneritz Agirre, Ana Mendanha Mendanha Falcão, David van Bruggen, Ka Wai Lee, Irene Knuesel et al.
    Nature
  132. Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury
    Authors: V Bellver-La, F Bretheau, B Mailhot, N Vallières, M Lessard, ME Janelle, N Vernoux, MÈ Tremblay, T Fuehrmann, MS Shoichet, S Lacroix
    Nat Commun, 2019-01-31;10(1):518.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  133. A New Patient-Derived Metastatic Glioblastoma Cell Line: Characterisation and Response to Sodium Selenite Anticancer Agent
    Authors: Sylvie Berthier, Louis Larrouquère, Pierre Champelovier, Edwige Col, Christine Lefebvre, Cécile Cottet-Rouselle et al.
    Cancers (Basel)
  134. Human ESC-Derived Chimeric Mouse Models of Huntington's Disease Reveal Cell-Intrinsic Defects in Glial Progenitor Cell Differentiation
    Authors: M Osipovitch, A Asenjo Mar, JN Mariani, A Cornwell, S Dhaliwal, L Zou, D Chandler-M, S Wang, X Li, SJ Benraiss, R Agate, A Lampp, A Benraiss, MS Windrem, SA Goldman
    Cell Stem Cell, 2018-12-13;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  135. Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis
    Authors: AM Falcão, D van Brugge, S Marques, M Meijer, S Jäkel, E Agirre, Samudyata, EM Floriddia, DP Vanichkina, C Ffrench-Co, A Williams, AO Guerreiro-, G Castelo-Br
    Nat. Med., 2018-11-12;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  136. NF-?B p65 directs sex-specific neuroprotection in human neurons
    Authors: LM Ruiz-Perer, L Schneider, BA Windmöller, J Müller, JFW Greiner, C Kaltschmid, B Kaltschmid
    Sci Rep, 2018-10-30;8(1):16012.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  137. Myostatin expression in the adult rat central nervous system
    Authors: Y Hayashi, S Mikawa, C Ogawa, K Masumoto, F Katou, K Sato
    J. Chem. Neuroanat., 2018-10-24;0(0):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  138. Species and cell-type properties of classically defined human and rodent neurons and glia
    Authors: Xiao Xu, Elitsa I Stoyanova, Agata E Lemiesz, Jie Xing, Deborah C Mash, Nathaniel Heintz
    eLife
  139. Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate
    Authors: Q Chen, J Wu, Q Ye, F Ma, Q Zhu, Y Wu, C Shan, X Xie, D Li, X Zhan, C Li, XF Li, X Qin, T Zhao, H Wu, PY Shi, J Man, CF Qin
    MBio, 2018-09-18;9(5):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  140. Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity
    Authors: Lucas Schirmer, Wiebke Möbius, Chao Zhao, Andrés Cruz-Herranz, Lucile Ben Haim, Christian Cordano et al.
    eLife
  141. Oligodendrocyte gene expression is reduced by and influences effects of chronic social stress in mice
    Authors: F Cathomas, D Azzinnari, G Bergamini, H Sigrist, M Buerge, V Hoop, B Wicki, L Goetze, S Soares, D Kukelova, E Seifritz, S Goebbels, KA Nave, M Said Ghand, C Seoighe, T Hildebrand, G Leparc, H Klein, E Stupka, B Hengerer, CR Pryce
    Genes Brain Behav., 2018-04-17;0(0):e12475.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  142. A TLR/AKT/FoxO3 immune tolerance-like pathway disrupts the repair capacity of oligodendrocyte progenitors
    Authors: T Srivastava, P Diba, JM Dean, F Banine, D Shaver, M Hagen, X Gong, W Su, B Emery, DL Marks, EN Harris, B Baggenstos, PH Weigel, LS Sherman, SA Back
    J. Clin. Invest., 2018-04-16;0(0):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  143. Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner
    Authors: M Datta, O Staszewski, E Raschi, M Frosch, N Hagemeyer, TL Tay, T Blank, M Kreutzfeld, D Merkler, S Ziegler-Wa, P Matthias, M Meyer-Lueh, M Prinz
    Immunity, 2018-03-13;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  144. Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma
    Authors: Ryan L. O’Hare Doig, Wissam Chiha, Marcus K. Giacci, Nathanael J. Yates, Carole A. Bartlett, Nicole M. Smith et al.
    BMC Neuroscience
  145. Targeting Glioma Stem Cell-Derived Pericytes Disrupts the Blood-Tumor Barrier and Improves Chemotherapeutic Efficacy
    Authors: W Zhou, C Chen, Y Shi, Q Wu, RC Gimple, X Fang, Z Huang, K Zhai, SQ Ke, YF Ping, H Feng, JN Rich, JS Yu, S Bao, XW Bian
    Cell Stem Cell, 2017-11-02;21(5):591-603.e4.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  146. Targeting glioma stem cells through combined BMI1 and EZH2 inhibition
    Authors: Xun Jin, Leo J. Y. Kim, Qiulian Wu, Lisa C. Wallace, Briana C. Prager, Tanwarat Sanvoranart et al.
    Nature Medicine
  147. The doublesex-related Dmrta2 safeguards neural progenitor maintenance involving transcriptional regulation of Hes1
    Authors: FI Young, M Keruzore, X Nan, N Gennet, EJ Bellefroid, M Li
    Proc. Natl. Acad. Sci. U.S.A., 2017-06-27;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  148. Adeno-Associated Viral Vectors Serotype 8 for Cell-Specific Delivery of Therapeutic Genes in the Central Nervous System
    Authors: Diego Pignataro, Diego Sucunza, Lucia Vanrell, Esperanza Lopez-Franco, Iria G. Dopeso-Reyes, Africa Vales et al.
    Frontiers in Neuroanatomy
  149. Delayed treatment of secondary degeneration following acute optic nerve transection using a combination of ion channel inhibitors
    Authors: NJ Yates, MK Giacci, RL O'Hare Doi, W Chiha, BE Ashworth, J Kenna, CA Bartlett, M Fitzgerald
    Neural Regen Res, 2017-02-01;12(2):307-316.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  150. Brain tissue banking for stem cells for our future
    Sci Rep, 2016-12-19;6(0):39394.
    Species: Human
    Sample Types: Tissue Homogenates
    Applications: IHC
  151. The intellectual disability protein PAK3 regulates oligodendrocyte precursor cell differentiation
    Authors: Majistor Raj Luxman Maglo Renkilaraj
    Neurobiol. Dis, 2016-12-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  152. Patched1 and Patched2 inhibit Smoothened non-cell autonomously
    Elife, 2016-08-23;5(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  153. A cord blood monocyte-derived cell therapy product accelerates brain remyelination
    JCI Insight, 2016-08-18;1(13):e86667.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  154. RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation
    Authors: Qi Xie
    J Clin Invest, 2016-06-20;126(7):2757-2772.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  155. Olig2 is expressed late in human eosinophil development and controls Siglec-8 expression
    J Leukoc Biol, 2016-05-06;0(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP
  156. Treatment Outcome and Prognostic Molecular Markers of Supratentorial Primitive Neuroectodermal Tumors
    Authors: SH Choi, SH Kim, KW Shim, JW Han, J Choi, DS Kim, CJ Lyu, JW Kim, CO Suh, J Cho
    PLoS ONE, 2016-04-13;11(4):e0153443.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  157. Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma
    Authors: Saverio Tardito, Anaïs Oudin, Shafiq U. Ahmed, Fred Fack, Olivier Keunen, Liang Zheng et al.
    Nature Cell Biology
  158. BDNF Pretreatment of Human Embryonic-Derived Neural Stem Cells Improves Cell Survival and Functional Recovery after Transplantation in Hypoxic–Ischemic Stroke
    Authors: Sahar Rosenblum, Tenille N. Smith, Nancy Wang, Joshua Y. Chua, Erick Westbroek, Kendrick Wang et al.
    Cell Transplantation
  159. Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug
    Authors: Julia Marschallinger, Iris Schäffner, Barbara Klein, Renate Gelfert, Francisco J. Rivera, Sebastian Illes et al.
    Nature Communications
  160. Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors
    Authors: Hélène O. B. Gautier, Kimberley A. Evans, Katrin Volbracht, Rachel James, Sergey Sitnikov, Iben Lundgaard et al.
    Nature Communications
  161. Connective-Tissue Growth Factor (CTGF/CCN2) Induces Astrogenesis and Fibronectin Expression of Embryonic Neural Cells In Vitro.
    Authors: Mendes F, Coelho Aguiar J, Kahn S, Reis A, Dubois L, Romao L, Ferreira L, Chneiweiss H, Moura Neto V, Abreu J
    PLoS ONE, 2015-08-04;10(8):e0133689.
    Species: Human
    Sample Types: Cell Lysates
  162. A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair.
    Authors: Rzem R, Achouri Y, Marbaix E, Schakman O, Wiame E, Marie S, Gailly P, Vincent M, Veiga-da-Cunha M, Van Schaftingen E
    PLoS ONE, 2015-03-12;10(3):e0119540.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  163. Mitochondrial control by DRP1 in brain tumor initiating cells.
    Authors: Xie Q, Wu Q, Horbinski C, Flavahan W, Yang K, Zhou W, Dombrowski S, Huang Z, Fang X, Shi Y, Ferguson A, Kashatus D, Bao S, Rich J
    Nat Neurosci, 2015-03-02;18(4):501-10.
    Species: Human
    Sample Types: Cell Lysates, Whole Tissue
    Applications: IHC, Western Blot
  164. Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth
    Authors: Wenchao Zhou, Susan Q. Ke, Zhi Huang, William Flavahan, Xiaoguang Fang, Jeremy Paul et al.
    Nature Cell Biology
  165. Notch signaling regulates motor neuron differentiation of human embryonic stem cells.
    Authors: Ben-Shushan E, Feldman E, Reubinoff B
    Stem Cells, 2015-02-01;33(2):403-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  166. Characterization of Np95 expression in mouse brain from embryo to adult: A novel marker for proliferating neural stem/precursor cells
    Authors: Naoya Murao, Taito Matsuda, Hirofumi Noguchi, Haruhiko Koseki, Masakazu Namihira, Kinichi Nakashima
    Neurogenesis (Austin)
  167. Distribution and phenotype of TrkB oligodendrocyte lineage cells in the adult rat spinal cord
    Authors: Aminata P. Coulibaly, Matthew R. Deer, Lori G. Isaacson
    Brain Research
  168. Nitric oxide-induced neuronal to glial lineage fate-change depends on NRSF/REST function in neural progenitor cells.
    Authors: Bergsland M, Covacu R, Perez Estrada C, Svensson M, Brundin L
    Stem Cells, 2014-09-01;32(9):2539-49.
    Species: Rat
    Sample Types: Whole Cells
    Applications: IHC
  169. CD133-enriched Xeno-Free human embryonic-derived neural stem cells expand rapidly in culture and do not form teratomas in immunodeficient mice
    Authors: Daniel L. Haus, Hal X. Nguyen, Eric M. Gold, Noriko Kamei, Harvey Perez, Harry D. Moore et al.
    Stem Cell Research
  170. Phage display discovery of novel molecular targets in glioblastoma-initiating cells.
    Authors: Liu, J K, Lubelski, D, Schonberg, D L, Wu, Q, Hale, J S, Flavahan, W A, Mulkearns-Hubert, E E, Man, J, Hjelmeland, A B, Yu, J, Lathia, J D, Rich, J N
    Cell Death Differ, 2014-05-16;21(8):1325-39.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells, Whole Tissue
    Applications: ICC, IHC, Western Blot
  171. Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy.
    Authors: Yan K, Wu Q, Yan D, Lee C, Rahim N, Tritschler I, DeVecchio J, Kalady M, Hjelmeland A, Rich J
    Genes Dev, 2014-05-01;28(10):1085-100.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  172. Temporal identity transition from Purkinje cell progenitors to GABAergic interneuron progenitors in the cerebellum.
    Authors: Seto Y, Nakatani T, Masuyama N, Taya S, Kumai M, Minaki Y, Hamaguchi A, Inoue Y, Inoue T, Miyashita S, Fujiyama T, Yamada M, Chapman H, Campbell K, Magnuson M, Wright C, Kawaguchi Y, Ikenaka K, Takebayashi H, Ishiwata S, Ono Y, Hoshino M
    Nat Commun, 2014-01-01;5(0):3337.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  173. BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells.
    Authors: Srikanth, Maya, Kim, Juno, Das, Sunit, Kessler, John A
    Mol Cancer Res, 2013-11-22;12(2):283-94.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  174. Safety of epicenter versus intact parenchyma as a transplantation site for human neural stem cells for spinal cord injury therapy.
    Authors: Piltti K, Salazar D, Uchida N, Cummings B, Anderson A
    Stem Cells Transl Med, 2013-02-14;2(3):204-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  175. Protein tyrosine phosphatase receptor type z negatively regulates oligodendrocyte differentiation and myelination.
    Authors: Kuboyama, Kazuya, Fujikawa, Akihiro, Masumura, Makoto, Suzuki, Ryoko, Matsumoto, Masahito, Noda, Masaharu
    PLoS ONE, 2012-11-07;7(11):e48797.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  176. The reactivity, distribution and abundance of Non-astrocytic Inner Retinal Glial (NIRG) cells are regulated by microglia, acute damage, and IGF1.
    Authors: Zelinka C, Scott M, Volkov L, Fischer A
    PLoS ONE, 2012-09-04;7(9):e44477.
    Species: Chicken
    Sample Types: Whole Tissue
    Applications: IHC
  177. N-Myc and GCN5 regulate significantly overlapping transcriptional programs in neural stem cells.
    Authors: Martinez-Cerdeno V, Lemen JM, Chan V, Wey A, Lin W, Dent SR, Knoepfler PS
    PLoS ONE, 2012-06-26;7(6):e39456.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  178. Timing of Intra-Arterial Neural Stem Cell Transplantation After Hypoxia–Ischemia Influences Cell Engraftment, Survival, and Differentiation
    Authors: Sahar Rosenblum, Nancy Wang, Tenille N. Smith, Arjun V. Pendharkar, Joshua Y. Chua, Harjus Birk et al.
    Stroke
  179. The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network
    Authors: M Fareh, L Turchi, V Virolle, D Debruyne, F Almairac, S de-la-Forest Divonne et al.
    Cell Death & Differentiation
  180. Human neural stem cells differentiate and promote locomotor recovery in an early chronic spinal cord injury NOD-scid mouse model.
    Authors: Salazar DL, Uchida N, Hamers FP, Cummings BJ, Anderson AJ
    PLoS ONE, 2010-08-18;5(8):e12272.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  181. Characterization of progenitor domains in the developing mouse thalamus.
    Authors: Vue TY, Aaker J, Taniguchi A
    J. Comp. Neurol., 2007-11-01;505(1):73-91.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  182. Increased neurogenesis and astrogenesis from neural progenitor cells grafted in the hippocampus of GFAP-/- Vim-/- mice.
    Authors: Widestrand A, Faijerson J, Wilhelmsson U, Smith PL, Li L, Sihlbom C, Eriksson PS, Pekny M
    Stem Cells, 2007-07-12;25(10):2619-27.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  183. Leukemia inhibitory factor promotes neural stem cell self-renewal in the adult brain.
    Authors: Bauer S, Patterson PH
    J. Neurosci., 2006-11-15;26(46):12089-99.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  184. STLV-1 Commonly Targets Neurons in the Brain of Asymptomatic Non-Human Primates
    Authors: B Rocamonde, S Alais, R Pelissier, V Moulin, B Rimbaud, R Lacoste, N Aurine, C Baquerre, B Pain, Y Tanaka, C Mathieu, H Dutartre
    MBio, 2023-02-21;0(0):e0352622.
  185. Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling
    Authors: Liu Z, Yan M, Lei W et al.
    The Journal of clinical investigation
  186. Niche-derived soluble DLK1 promotes glioma growth
    Authors: Grassi E, Jeannot P, Pantazopoulou V et al.
    Neoplasia
  187. PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells
    Authors: Huang T, Yang Y, Song X et al.
    Molecular cell
  188. Sox2 is essential for oligodendroglial proliferation and differentiation during postnatal brain myelination and CNS remyelination
    Authors: S Zhang, X Zhu, X Gui, C Croteau, L Song, J Xu, A Wang, P Bannerman, F Guo
    J. Neurosci., 2018-01-15;0(0):.
  189. Estrogen Inhibits LDL (Low-Density Lipoprotein) Transcytosis by Human Coronary Artery Endothelial Cells via GPER (G-Protein-Coupled Estrogen Receptor) and SR-BI (Scavenger Receptor Class B Type 1).
    Authors: Ghaffari S, Naderi Nabi F et al.
    Arterioscler Thromb Vasc Biol

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Human/Mouse/Rat Olig2 Antibody
By Anonymous on 07/09/2019
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Spinal cord Species: Mouse

This antibody worked nicely 1:500 or 1:1000 of mouse spinal cord perfused with 4% PFA.

Immunocytochemistry/Immunofluorescence Human/Mouse/Rat Olig2 Antibody AF2418
Human/Mouse/Rat Olig2 Antibody
By Anonymous on 06/20/2018
Application: IHC Sample Tested: Adult brain Species: Mouse

This antibody worked beautifully at 1:2000 in 30um free-floating sections of adult (P25) mouse brain perfused with 4% PFA and cryoprotected. Region imaged: corpus callosum above hippocampus.

Protocol:
1. Antigen Retrieval: 100mM Sodium Citrate pH6.0, 0.05% Tween, in microwave
2. Rinse sections PBS once
3. Block in 5% NDS in PBSTx 1% RT for 1 hour
4. Primary Antibody (1:2000) in 1% NDS in PBSTx 0.3% (Incubate RT overnight on shaker)
5. Wash 3x 10 min PBS
6. Secondary Antibody (1:600) in 1% NDS in PBSTx 0.3% (Incubate RT 2h on shaker)
7. Wash 3x 10 min PBS
8. Mount on slides in water and let dry
9. Coverslip using Prolong Gold

Immunohistochemistry Human/Mouse/Rat Olig2 Antibody AF2418
Human Olig2 Antibody
By Anonymous on 01/04/2018
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Glioma Species: Human

Glioma xenografted in NOD SCID mice -> olig2 in red

Immunocytochemistry/Immunofluorescence Human Olig2 Antibody AF2418
Human Olig2 Antibody
By Anonymous on 12/07/2015
Application: Affinity Purification Sample Tested: Brain sections Species: Rat Sprague Dawley

Dilution 1:500