Human MMP‑25/MT6-MMP Hemopexin Domain Antibody Summary
NS0‑expressed recombinant human MMP-25.
Pro314-Cys508
Accession # Q9NPA2
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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MMP‑25/MT6‑MMP in Human Lung. MMP-25/MT6-MMP was detected in immersion fixed paraffin-embedded sections of human lung using Mouse Anti-Human MMP-25/MT6-MMP Hemopexin Domain Monoclonal Antibody (Catalog # MAB11421) at 8 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counter-stained with hematoxylin (blue). Specific labeling was localized to the cytoplasm of epithelial cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: MMP-25/MT6-MMP
Matrix Metalloproteinase 25 (MMP-25), also known as MT6-MMP or Leukolysin, is a GPI-linked protease expressed by neutrophils. The extracellular domain of MMP-25 consists of a pro region, a catalytic domain and a hemopexin domain. MMP-25 cleaves collagen type 4, gelatin, fibronectin and fibrin.
Product Datasheets
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